ENSMUSG00000032368 (Zic1)

mus musculus

zinc finger protein of the cerebellum 1

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Mus musculus
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Showing 32 experiments:
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.3248 × 10-127-10.4
Zic1'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
8.3645 × 10-45-10.3
Zic1'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
4.5022 × 10-9-7.2
Zic1'Wnt1Cre Ezh2lox/lox' vs 'control'genotypeExpression data from E11.5 mouse branchial arch 1 (BA1) - comparison between Ezh2lox/lox and Wnt1Cre Ezh2lox/lox embryos
Adjusted p-valueLog2-fold change
1.2504 × 10-31-6.7
Zic1'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
7.7036 × 10-145.9
Zic1'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
1.4756 × 10-565.7
Zic1'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
1.4906 × 10-2-5.1
Zic1'subventicular zone of the lateral ventricle' vs 'cerebellum'organism partExpression data from adult Shh-responding astroglia cells in mice
Adjusted p-valueLog2-fold change
1.7185 × 10-2-4.8
Zic1'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
2.3315 × 10-9-4.6
Zic1'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
8.7025 × 10-64.6
Zic1'Cbfb knockout' vs 'control of Cbfb knockout'genotypeTranscription profiling by array of Mus musculus expressing Cbfb-MYH11
Adjusted p-valueLog2-fold change
3.0856 × 10-2-4.2
Zic1'hippocampus' vs 'cerebellum'organism partExpression data from adult Shh-responding astroglia cells in mice
Adjusted p-valueLog2-fold change
1.9331 × 10-84.1
Zic1'BCL9 HD1/HD2 mutant' vs 'wild type genotype'genotypeRNA-seq experiment of developing mouse forelimbs, comparing Bcl9/9l mutant with control littermates.
Adjusted p-valueLog2-fold change
3.844 × 10-11-3.7
Zic1'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.968 × 10-33.2
Zic1'embryoid body' vs 'embryonic stem cell' on 'Affymetrix GeneChip Array 430A 2.0'developmental stageGene expression profile of J1 embryonic stem cells and J1 embryoid bodies
Adjusted p-valueLog2-fold change
1.6049 × 10-149-3.1
Zic1'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
1.0685 × 10-9-3.1
Zic1'ATF5 knockdown' vs 'wild type' in 'DMSO'compound, genotypeMicroarray to find ATF5 dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
7.8343 × 10-43
Zic1'calorie restricted diet' vs 'normal diet' at '15 month'age, dietTranscription profiling by array of cochleae from mice fed a calorie-restricted diet
Adjusted p-valueLog2-fold change
3.9645 × 10-3-3
Zic1'Bmi1-overexpressing lentiviral vector' vs 'empty vector control'genotypeControl and Bmi1-overexpressing adult murine neural stem cells
Adjusted p-valueLog2-fold change
2.5831 × 10-22.7
Zic1'HoxA11 HoxD11 null' vs 'wild type' in 'metanephric mesenchyme'genotype, organism partTranscription profiling by array of wild type and HoxA11 metenephric mesenchyme and ureteric bud from embryonic day 11.5 mice
Adjusted p-valueLog2-fold change
1.1667 × 10-42.6
Zic1'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.5611 × 10-22.5
Zic1'CD2314' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
2.2946 × 10-22.5
Zic1'Irs gene knockout' vs 'wild type genotype'genotypeTranscription profiling of mouse brown preadipocytes from wild type and IRS knock-out cell lines
Adjusted p-valueLog2-fold change
2.1693 × 10-42.4
Zic1'tumor' vs 'normal' in 'liver'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.3792 × 10-2-2.4
Zic1'30 month' vs '5 month' in 'male'age, block, sexExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Adjusted p-valueLog2-fold change
3.3641 × 10-4-2.3
Zic1'dmrt1 knockout' vs 'wild type' in '129Sv'genotype, strainDmrt1 (doublesex and mab-3 related transcription factor 1) conditional knockout expression analysis of E15.5 testes.
Adjusted p-valueLog2-fold change
3.3822 × 10-152.1
Zic1'12 nanomolar; retinoic acid' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid
Adjusted p-valueLog2-fold change
3.3787 × 10-102.1
Zic1'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
3.5647 × 10-92
Zic1'336 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
4.0286 × 10-32
Zic1'19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
3.2214 × 10-4-1.9
Zic1'96 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
9.5734 × 10-41.9
Zic1'NeoNull (aflox/null); frontal nasal' vs 'wild type; frontal nasal'genotype, organism partTfap2a dependnt cha
Adjusted p-valueLog2-fold change
7.6311 × 10-3-1.9
Zic1'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.7759 × 10-21.9
Zic1'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
1.7945 × 10-21.9
Zic1'CD2314' vs 'none' at '6 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
3.5962 × 10-21.9
Zic1'p150 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA'RNA interferenceRNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells
Adjusted p-valueLog2-fold change
2.6992 × 10-5-1.8
Zic1'bisphenol AF; 10 micromolar' vs 'vehicle'compoundTranscriptomic analyses of 11.5 dpc female germ cell (mouse) exposed or not to Bisphenol A analogues (BPAF and BADGE)
Adjusted p-valueLog2-fold change
1.0909 × 10-31.8
Zic1'HP1g knockdown' vs 'control' in 'embryoid body'developmental stage, genotypeTranscription profiling of mouse embryonic stem cell line CGR8 transfected with control shRNA and shRNA against HP1g in two different developmental stages
Adjusted p-valueLog2-fold change
1.3316 × 10-2-1.8
Zic1'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'separate'genotype, growth conditionRNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions
Adjusted p-valueLog2-fold change
3.7827 × 10-21.7
Zic1'Alk5 fl/fl; Wnt1-Cre' vs 'control'genotypeGene expression profiling of the tongue bud from Alk5 mutant mouse models
Adjusted p-valueLog2-fold change
2.5284 × 10-4-1.6
Zic1'144 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
3.6739 × 10-41.6
Zic1'E2f1, E2f2, E2f3 triple knockout' vs 'control' at 'neonate'developmental stage, genotypeExpression data from lenses triply deficient for E2F1, E2F2, and E2F3 transcription factors
Adjusted p-valueLog2-fold change
3.0392 × 10-2-1.6
Zic1'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
3.7513 × 10-6-1.5
Zic1'MEF; transduced with MyoD lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
3.9394 × 10-41.5
Zic1'Foxd3 knockout' vs 'control'phenotypeExpression data from embryonic stem cells differentiation
Adjusted p-valueLog2-fold change
8.4543 × 10-4-1.5
Zic1'48 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
2.2164 × 10-411.4
Zic1'Meis1; Meis2 conditional knockout' vs 'wild type phenotype'phenotypeMeis homeobox genes control cell competence within the eye-specified neuroepithelium (RNA-seq)
Adjusted p-valueLog2-fold change
7.0209 × 10-26-1.4
Zic1'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
2.088 × 10-21.4
Zic1'NeuroD1 conditional knockout' vs 'control' in 'retina' at 'Zeitgeber time 20'genotype, organism part, sampling time pointGene expression profile of retina and pineal gland of NeuroD1 conditional knockout mice
Adjusted p-valueLog2-fold change
2.8836 × 10-7-1.3
Zic1'5-aza-2'-deoxycytidine; 5 micromolar' vs 'none'compoundTranscription profiling by array of mouse primary dermal fibroblasts after treatment with 5-aza-2'-deoxycytidine
Adjusted p-valueLog2-fold change
3.2103 × 10-7-1.3
Zic1'NrlGFP positive' vs 'NrlGFP negative'phenotypeTranscription profiling by array of photoreceptor precursor cells selected via cell surface antigen expression.
Adjusted p-valueLog2-fold change
2.7071 × 10-4-1.3
Zic1'24 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
2.1804 × 10-21.3
Zic1'left ventricle' vs 'right ventricle' in 'embryonic day 14.5'developmental stage, organism partTranscriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome
Adjusted p-valueLog2-fold change
4.3016 × 10-21.3
Zic1'20 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance
Adjusted p-valueLog2-fold change
3.3072 × 10-31.2
Zic1'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
4.1798 × 10-31.2
Zic1'no limb muscle' vs 'wild type'phenotypeTranscription profiling by array of TS23 humerus tissue from muscle-less mutant (splotch-delayed) mice and control littermates to identify differentially expressed genes between muscle-less and control embryonic (TS23) humerus tissue, in order to determine mechanosensitive genes that impact skeletal development
Adjusted p-valueLog2-fold change
4.2158 × 10-3-1.2
Zic1'side population cells' vs 'main population cells' in 'muscle'cell type, organism partGene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow
Adjusted p-valueLog2-fold change
5.0194 × 10-3-1.2
Zic1'NOD allele at SNP rs50454566' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene
Adjusted p-valueLog2-fold change
1.529 × 10-2-1.2
Zic1'129S1 allele at SNP rs50454566' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene
Adjusted p-valueLog2-fold change
1.6063 × 10-2-1.2
Zic1'rab3a D77G mutant' vs 'wild type genotype' in 'litter 1; hippocampus' on 'Affymetrix MOE430B'generation, genotype, organism partTranscription profiling of mouse Earlybird (rab3a D77G) mutants and knockout of Rab3a on gene expression in the cortex and hippocampus
Adjusted p-valueLog2-fold change
2.3995 × 10-2-1.2
Zic1'normal skin; PKC alpha-/-' vs 'normal skin; wild type genotype'clinical history, genotypeAltered dermal architecture in PKCα-/- skin
Adjusted p-valueLog2-fold change
2.5363 × 10-21.2
Zic1'embryoid body' vs 'embryonic stem cell' on 'Affymetrix GeneChip Array MOE430B'developmental stageGene expression profile of J1 embryonic stem cells and J1 embryoid bodies
Adjusted p-valueLog2-fold change
4.5127 × 10-20-1.1
Zic1'proliferating progenitor' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
6.0338 × 10-41.1
Zic1'transgenic' vs 'wild type' in '121 day; 129Sv'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
1.7074 × 10-31.1
Zic1'Chikungunya virus; early stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
8.0842 × 10-31.1
Zic1'Sall4 -/-' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells in response to changes in Sall4
Adjusted p-valueLog2-fold change
2.1569 × 10-2-1.1
Zic1'21 percent oxygen, 37 degree Celsius, no serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
3.2275 × 10-41
Zic1'Chikungunya virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
5.248 × 10-31
Zic1'dominant active mutant DREAM transgenic' vs 'wild type'genotypeTranscription profiling by array of hippocampus from transgenic mice expressing a Ca2+-insensitive/CREB-independent dominant active mutant DREAM
Adjusted p-valueLog2-fold change
4.8049 × 10-21
Zic1'CD2314 and BIO' vs 'none' at '6 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Synonym
odd-paired homolog
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
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UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
ILMN_2491186, A_52_P428654, 4608317, 5114587, 5409291, 5537692, 1423477_at, A_51_P194230, 5032892, 4606198, 10595695, 5540613, 4942695, 5400972, 104169_at, 1439627_at, 166858_at, 4590275, 5433923, 5302501, D32167_s_at, 4373386, 17529679, A_55_P2009774