8.4 | | Lif | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
8.2 | | Lif | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
7.9 | | Lif | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
7.1 | | Lif | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
7.1 | | Lif | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
6.1 | | Lif | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
6 | | Lif | 'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
5.9 | | Lif | 'Porphyromonas gingivalis; normal' vs 'normal' | infect, phenotype | hyperlipidemia impaired innate response |
5.5 | | Lif | 'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
5.5 | | Lif | 'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'wild type' | compound, genotype | Inhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2) |
5.3 | | Lif | 'Porphyromonas gingivalis; hyperlipidemia' vs 'normal' | infect, phenotype | hyperlipidemia impaired innate response |
4.7 | | Lif | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
4.7 | | Lif | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
4.6 | | Lif | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
4.6 | | Lif | 'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
4.6 | | Lif | 'ulcer' vs 'distant normal tissue' in 'Bmp4 overexpression' | genotype, sampling site, time | Intestinal ulcers from biopsy-wounded wild-type and Bmp4-overexpressing mice |
4.5 | | Lif | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
4.5 | | Lif | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
4.4 | | Lif | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
4.4 | | Lif | 'Pkhd1Cre; Pkd2 F/F; miR-21null' vs 'wild type' | genotype | Next Generation Sequencing of PKD2 mutant mice kidneys |
4.4 | | Lif | 'trans-tympanically injected with Hemophilus influenza' vs 'control' | treatment | Otitis Media Impact on Middle Ear |
4.3 | | Lif | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
4.3 | | Lif | 'Pkhd1Cre; Pkd2 F/F' vs 'wild type' | genotype | Next Generation Sequencing of PKD2 mutant mice kidneys |
4.2 | | Lif | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
4.1 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
4.1 | | Lif | 'Adjuvant System 03' vs 'PBS' in 'lymph node' at '4 hour' | organism part, stimulus, time | Expression data from draining lymph node and muscle of mice immunised with AS03 or PBS |
4 | | Lif | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
4 | | Lif | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.9 | | Lif | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
3.9 | | Lif | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.9 | | Lif | 'neural progenitor cell' vs 'niche cell' | cell type | Transcription profiling by high throughput sequencing of three populations of primary dentate gyrus cells |
3.8 | | Lif | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
3.8 | | Lif | 'Staphylococcus aureus cutaneous infection' vs 'none' in 'wild type' | disease, genotype | Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice |
3.6 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.6 | | Lif | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
3.6 | | Lif | 'MEF2A knockout' vs 'wild type genotype' in 'Hoxb8-FL; lipopolysaccharide; 10 nanogram per milliliter' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
3.6 | | Lif | 'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-' | compound, genotype | Inhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2) |
3.5 | | Lif | 'SMRT shRNA' vs 'none' in 'CpG' at '6 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
3.4 | | Lif | 'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
3.4 | | Lif | 'sham-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle' | clinical treatment | Transcription profiling by array of mice with epileptic tolerance |
3.4 | | Lif | 'Adjuvant System 03' vs 'PBS' in 'lymph node' at '6 hour' | organism part, stimulus, time | Expression data from draining lymph node and muscle of mice immunised with AS03 or PBS |
3.4 | | Lif | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
3.3 | | Lif | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2-GFP knockin; Egr2-GFP high' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
3.3 | | Lif | 'lipopolysaccharide' vs 'none' in 'bone marrow; wild type' | cell type, compound, genotype | Transcription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice |
3.3 | | Lif | 'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
3.3 | | Lif | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
3.2 | | Lif | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
3.2 | | Lif | 'trans-tympanically injected with Hemophilus influenza' vs 'control' | treatment | Otitis Media Impact on Inner Ear |
3.2 | | Lif | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.2 | | Lif | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
3.1 | | Lif | 'interleukin-36 gamma; 30 microgram per liter' vs 'none; ' | compound | Transcriptional profiling of colonic mouse fibroblasts stimulated with interleukin-36 gamma |
3.1 | | Lif | 'Gata6 knockout' vs 'wild type' | phenotype | Global gene expression in the adult Gata6 null mouse pancreas |
3 | | Lif | "tunicamycin; 2 microgram per milliliter" vs "DMSO" in "PWK/PhJ" | compound, strain | Transcription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress |
3 | | Lif | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
3 | | Lif | 'liver-specific Cnot3 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
2.9 | | Lif | 'seizure-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle' | clinical treatment | Transcription profiling by array of mice with epileptic tolerance |
2.8 | | Lif | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
2.8 | | Lif | 'expanded on HUVEC and m5GF in the presence of mD1R for 7 days' vs 'control' | treatment | Expression data from cultured c-Kit+Sca-1+Lin- (KSL)cells |
2.7 | | Lif | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
2.7 | | Lif | 'Adjuvant System 03' at '4 hour' vs 'none' | compound, time | RNA-Seq of RAW 264.7 cells stimulated with the AS03 adjuvant after 4 and 8 hours |
2.7 | | Lif | 'liver-specific Cnot1 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
2.7 | | Lif | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.7 | | Lif | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.6 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.6 | | Lif | 'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
2.6 | | Lif | 'Adjuvant System 03' at '8 hour' vs 'none' | compound, time | RNA-Seq of RAW 264.7 cells stimulated with the AS03 adjuvant after 4 and 8 hours |
2.6 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2.6 | | Lif | 'glioma' vs 'normal' | disease | Gene expression profile between glioma associated macrophages and normal brain tissue associated macrophages |
2.5 | | Lif | 'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.5 | | Lif | 'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
2.5 | | Lif | 'acute myeloid leukemia' vs 'myeloproliferative disorder' | disease | Transcription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm |
2.4 | | Lif | 'Ts1Rhr; KRASG12D' vs 'wild type genotype' | genotype | RNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D |
2.4 | | Lif | "tunicamycin; 2 microgram per milliliter" vs "DMSO" in "A/J" | compound, strain | Transcription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress |
2.4 | | Lif | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
2.4 | | Lif | 'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
2.4 | | Lif | 'carcinoma' vs 'normal' | disease | Expression data from (mouse) normal lung fibroblasts and carcinoma-associated fibroblasts |
2.3 | | Lif | 'KRASG12D' vs 'wild type genotype' | genotype | RNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D |
2.3 | | Lif | 'CD36 knockout' vs 'wild type genotype' in 'oxidized low density lipoprotein; 25 microgram per milliliter' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
-2.3 | | Lif | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '10 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
2.2 | | Lif | "tunicamycin; 2 microgram per milliliter" vs "DMSO" in "C57BL/6J x 129S1Sv/ImJ F1 cross" | compound, strain | Transcription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress |
2.2 | | Lif | 'SMRT shRNA' vs 'none' in 'none' at '0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
2.2 | | Lif | 'BAG6 homozygous knockout' vs 'wild type genotype' | genotype | Transcription profiling of B16V mouse melanoma cells after BAG6 knockout to study impacts on extracellular vesicle mRNA cargo |
-2.2 | | Lif | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD8-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
2.2 | | Lif | 'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-2.2 | | Lif | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '14 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
2.2 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.2 | | Lif | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2.2 | | Lif | 'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; STI571 treated' vs 'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; untreated' | cell type, treatment | Gene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice |
2.2 | | Lif | 'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
2.2 | | Lif | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-2.2 | | Lif | 'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
2.1 | | Lif | 'S-(1,2-dichlorovinyl)-L-cysteine; 15 milligram per kilogram; renal injury; 1 week' vs 'none; normal' | compound, disease, time | Expression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC |
2.1 | | Lif | 'Plasmodium berghei ANKA' at '7 day' vs 'none' at '0 day' in 'none' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
-2.1 | | Lif | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
2.1 | | Lif | 'NeuroD1 conditional knockout' vs 'control' in 'retina' at 'Zeitgeber time 20' | genotype, organism part, sampling time point | Gene expression profile of retina and pineal gland of NeuroD1 conditional knockout mice |
2.1 | | Lif | 'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
-2 | | Lif | 'MHC II overexpression'vs 'empty retroviral vector' | phenotype | Effect of MHC II expression in pro-B cells: F6 leukaemic cell line |
2 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2 | | Lif | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
2 | | Lif | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2; Il22-/-' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
-2 | | Lif | 'dexamethasone (1 μM) and GW7647 (0.5 μM)' vs 'none' | compound | RNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS |
2 | | Lif | 'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
2 | | Lif | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
2 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2 | | Lif | 'Bcl6 -/- BCR-ABL1-transformed B cell precursors; STI571 treated' vs 'Bcl6 -/- BCR-ABL1-transformed B cell precursors; untreated' | cell type, treatment | Gene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice |
2 | | Lif | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2 | | Lif | 'Macrophage of F4/80+, CD11b+, CD11c-+; obese leptin-deficient' vs 'Macrophage of F4/80+, CD11b+, CD11c-+; control' | cell type, genotype | Expression data from mouse adipose tissue macrophage |
2 | | Lif | 'Staphylococcus aureus cutaneous infection' vs 'none' in 'IL-1R knockout' | disease, genotype | Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice |
-1.9 | | Lif | '129S1 allele at SNP rs50454566' vs 'wild type genotype' | genotype | RNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene |
-1.9 | | Lif | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
1.9 | | Lif | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
1.9 | | Lif | 'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-1.9 | | Lif | 'mutant MyoD expression' at '12 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
1.9 | | Lif | 'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.9 | | Lif | 'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.9 | | Lif | 'diphtheria toxin; 30 nanogram per gram' vs 'none' | stimulus | RNA-seq of mouse brain tissue repopulating microglia in response to traumatic brain injury |
-1.9 | | Lif | 'myeloid progenitor cell; FoxO1/3/4 triple knockout' vs 'myeloid progenitor cell; wild type genotype' | cell type, genotype | Transcription profiling of bone marrow hematopoietic stem cells and myeloid progenitors from mice with conditional deletion of Forkhead O (FoxO) family of transcription factors |
-1.9 | | Lif | 'FusΔNLS/+' vs 'wild type genotype' at '12 hour' | genotype, time | Mutant FUS triggers age-dependent synaptic impairment in presymptomatic ALS-FUS mice (RNA-seq part2) |
1.8 | | Lif | "tunicamycin; 2 microgram per milliliter" vs "DMSO" in "C57BL/6J x NZO/H1LtJ F1 cross" | compound, strain | Transcription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress |
1.8 | | Lif | '0.45 micromolar; 5-fluourouracil' vs 'none' at '24 hour' | compound, time | Transcription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid |
1.8 | | Lif | 'TNFα' vs 'none' in 'IRAK1BP1 KO' | genotype, treatment | Identification of TNFα-induced genes that are IRAK1BP1 dependent |
-1.8 | | Lif | 'mutant MyoD expression' at '24 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
1.8 | | Lif | 'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.8 | | Lif | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
1.8 | | Lif | 'NeuroD1 conditional knockout' vs 'control' in 'retina' at 'Zeitgeber time 6' | genotype, organism part, sampling time point | Gene expression profile of retina and pineal gland of NeuroD1 conditional knockout mice |
1.8 | | Lif | 'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '30 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
1.8 | | Lif | 'AAV9-Ccnt1;Myh6-cre;LSL-R26CAG-c-MycERT2/+' vs 'AAV9-Ccnt1;LSL-R26CAG-c-MycERT2/+' | genotype | RNA-seq of purified cardiomocytes from adult mice (+/- AAV-CCNT1) 4 hours post MycER activation compared controls. |
1.8 | | Lif | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.8 | | Lif | 'Fhl1 knockdown by siRNA' vs 'wild type' at '3 day' | phenotype, time | 3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1 |
1.8 | | Lif | 'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; lipopolysaccharide; 10 nanogram per milliliter' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.8 | | Lif | 'Trp53 Arg178Asp' vs 'wild type genotype' in 'Nutlin-3a; 10 micromolar' | compound, phenotype | Residual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy |
-1.8 | | Lif | 'Trp53 knockout' vs 'wild type genotype' in 'Nutlin-3a; 10 micromolar' | compound, phenotype | Residual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy |
1.8 | | Lif | 'liver specific SMARCB1 knockout' vs 'wild type' | phenotype | TP53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors |
-1.8 | | Lif | 'IL-1R knockout' vs 'wild type' in 'Staphylococcus aureus cutaneous infection' | disease, genotype | Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice |
1.8 | | Lif | 'interleukin-22' vs 'phosphate buffered saline' in 'Influenza A virus' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
1.7 | | Lif | '6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
1.7 | | Lif | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1.7 | | Lif | 'ATF3 -/-' vs 'wild type' in '10 nanogram per milliliter; lipopolysaccharide' at '1 hour' | compound, genotype, time | Transcription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide |
-1.7 | | Lif | 'dexamethasone; 1 micromolar' vs 'none' | compound | RNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS |
1.7 | | Lif | 'cut nerve; 7 day' vs 'none' | injury, protocol, time | Changes in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury |
-1.7 | | Lif | 'mutant MyoD expression' at '6 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
1.7 | | Lif | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
1.7 | | Lif | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
-1.7 | | Lif | 'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control' | phenotype | Temporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice |
1.7 | | Lif | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.6 | | Lif | "tunicamycin; 2 microgram per milliliter" vs "DMSO" in "C57BL/6J x WSB/EiJ F1 cross" | compound, strain | Transcription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress |
1.6 | | Lif | 'Aatf homozygous knockout' vs 'wild type genotype' | genotype | RNA-seq experiment to investigate the effect of inactivating the Apoptosis Antagonizing Transcription Factor (Aatf) |
1.6 | | Lif | 'Sall4 homozygous knockout' vs 'wild type genotype' | genotype | RNA-Seq of Sall4 mutants in mouse embryonic stem cells |
-1.6 | | Lif | 'induced neural stem cell' vs 'mouse embryonic fibroblast cell' | cell type | Gene expression profile of mouse induced neural stem cells |
-1.6 | | Lif | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '60 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.6 | | Lif | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
1.6 | | Lif | 'unilateral ureteral obstruction' vs 'sham' in 'wild type' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
1.6 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NZO/HILtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.6 | | Lif | 'Influenza A virus' vs 'mock' in 'interleukin-22' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
1.6 | | Lif | 'LDB1 knock-down' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
1.5 | | Lif | 'shear stressing' vs 'none' | stimulus | RNA seq of fluid shear stress treated mouse renal epithelial cells |
-1.5 | | Lif | 'Irx3 knockout' vs 'control' at '7 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
-1.5 | | Lif | 'Duchenne muscular dystrophy' vs 'normal' | disease | RNA-seq comparison of immortalised myoblasts from dystrophic and WT mice |
1.5 | | Lif | 'TGFβ, 5 nanogram per milliliter' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
1.5 | | Lif | 'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
1.5 | | Lif | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
1.5 | | Lif | 'anti-CD3/anti-CD28' vs 'none' in 'FOXP3 overexpression' | genotype, stimulus | Transcription profiling by array of FOXP3 overexpression in resting and activated mouse CD4+ T cells |
1.5 | | Lif | 'West Nile virus; late stage encephalitis' vs 'mock infection' | infect, time | Transcriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection |
-1.5 | | Lif | 'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
-1.5 | | Lif | 'induced neural stem cell' vs 'neural stem cell' | cell type | Gene expression profile of mouse induced neural stem cells |
-1.5 | | Lif | 'CpG; 6 hour' vs 'none; 0 hour' in 'none' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
1.5 | | Lif | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
1.5 | | Lif | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-1.5 | | Lif | 'cycloheximide and 100 unit per milliliter interferon gamma' vs 'DMSO' | compound | Dissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression |
1.5 | | Lif | 'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.5 | | Lif | '3 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
1.5 | | Lif | '4 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
1.5 | | Lif | 'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week' | age, genotype | Prevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA |
1.5 | | Lif | 'Metarhizium anisopliae crude antigen' vs 'vehicle' at '3 hour' | compound, time | Transcription profiling of mouse lungs following exposure to agents of high or low allergenicity |
1.5 | | Lif | 'H-Ras expression; c-Myc activation' vs 'wild type' | phenotype | RNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls. |
-1.5 | | Lif | 'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1.4 | | Lif | 'shear stressing' vs 'none' | stimulus | RNA seq of fluid shear stress treated mouse Pkd1-/- renal epithelial cells |
1.4 | | Lif | 'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.4 | | Lif | '6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
1.4 | | Lif | 'West Nile virus; late stage encephalitis' vs 'early stage encephalitis' | infect, time | Transcriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection |
1.4 | | Lif | 'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.4 | | Lif | 'Gprc5a knockout' vs 'control' | genotype | Gene expression profile of lung epithelial cells cultured from normal tracheas of Gprc5a knockout and wild-type mice |
1.4 | | Lif | 'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.4 | | Lif | 'TGF-beta; 15 nanogram per milliliter' vs 'control' | compound | TGF beta Dosage Experiment |
1.4 | | Lif | 'TNFα' vs 'none' in 'wild type' | genotype, treatment | Identification of TNFα-induced genes that are IRAK1BP1 dependent |
1.4 | | Lif | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.4 | | Lif | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.4 | | Lif | 'inhibition of BRD4 with JQ1' vs 'DMSO' | treatment | Expression Data For BRD4 Inhibition |
1.4 | | Lif | 'SARS coronavirus MA15; 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.4 | | Lif | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1.4 | | Lif | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1.4 | | Lif | 'tristetrapolin knockout' vs 'wild type' in 'none' at '0 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
-1.4 | | Lif | 'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
1.4 | | Lif | 'wild type; mature luminal' vs 'wild type; MaSC/basal' | cell type, genotype | Expression data from sorted control and Pygo2-null mouse mammary stem/basal cells |
1.3 | | Lif | 'Debaryomyces hansenii' at '2 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
-1.3 | | Lif | 'XBP1s overexpression' vs 'wild type genotype' in 'none' | compound, genotype | Overexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment |
1.3 | | Lif | 'anti-CD3/anti-CD28' vs 'none' in 'empty vector' | genotype, stimulus | Transcription profiling by array of FOXP3 overexpression in resting and activated mouse CD4+ T cells |
1.3 | | Lif | '4-hydroxytamoxifen-mediated deletion of Prmt5' vs 'wild type' in 'mouse neural progenitor cell' | cell type, phenotype | Transcription profiling by high throughput sequencing of murine neural stem/progenitor cells lacking PRMT5 over control |
-1.3 | | Lif | '7 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-1.3 | | Lif | 'interleukin-3 and interleukin-33' vs 'interleukin-3' | growth condition | Stem cell factor programs the mast cell activation phenotype |
1.3 | | Lif | '5-aza-2'-deoxycytidine; 5 micromolar' vs 'none' | compound | Transcription profiling by array of mouse primary dermal fibroblasts after treatment with 5-aza-2'-deoxycytidine |
-1.3 | | Lif | 'Debaryomyces hansenii' at '24 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
1.3 | | Lif | '500 micromolar palmitate' vs '1 volume percent bovine serum albumin' | compound | Transcription profiling of mouse C2C12 myotubes treated overnight with 500 uM palmitate or 1% bovine serum albumin control to identify mediators of obesity-linked reductions in PGC-1 |
-1.3 | | Lif | '7-ketocholesterol' vs 'vehicle (cyclodextrin)' | compound, time | Array results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol |
-1.3 | | Lif | '5,9-endoperoxy-cholest-7-en-3β,6α-diol' vs 'vehicle (cyclodextrin)' | compound, time | Array results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol |
1.3 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.3 | | Lif | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.3 | | Lif | '48 hour after induction of differentiation' vs 'induction of differentiation' | compound, sampling time point | Expression Profiling of Early Myogenesis - Affymetrix Dataset |
1.3 | | Lif | 'hyperoxia' vs 'control' in 'female' | sex, stimulus | Transcription profiling by array of lung tissues from wild-type male and female C56BL/6J mice either maintained in room air or exposed to hyperoxia (FiO2>95%) for 48 hours |
1.3 | | Lif | 'RBPjk null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
1.3 | | Lif | 'recombinant human interleukin-2; 100 unit per milliliter; 8 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
1.3 | | Lif | 'recombinant human interleukin-2; 100 unit per milliliter; 10 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
1.3 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NZO/HILtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.3 | | Lif | 'anti-mPDL1; anti-mCTLA4; 10 milligram per kilogram' vs 'none' at '7 day' | compound, time | RNAseq of tumor samples from CT26 syngeneic mouse treated with a PD-L1 and CTLA-4 immunotherapy combination |
1.3 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.3 | | Lif | 'oscillating fluid flow' vs 'sham' at '2 hour' | time, treatment | Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways |
1.3 | | Lif | 'K-ras mutant/Wt1-null' vs 'wild type' | genotype | Transcription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts |
-1.2 | | Lif | '6 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-1.2 | | Lif | '5 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-1.2 | | Lif | 'PUGKO' vs 'wild type' | genotype | Expression profiling of the uteri of progesterone induced uterine gland knockout mice |
-1.2 | | Lif | 'cholesterol' vs 'vehicle (cyclodextrin)' | compound, time | Array results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol |
-1.2 | | Lif | '4 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
1.2 | | Lif | '4-oxoretinoic acid; 5 micromolar' vs 'none' in 'wild type phenotype' | compound, phenotype | RNA Seq of control and Cyp26b1KO HSCs after 24h of in vitro culture and treatment |
1.2 | | Lif | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1.2 | | Lif | 'RBM20 antisense oligonucleotide' vs 'none' in 'wild type genotype' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |
1.2 | | Lif | '6 hour' vs '3 hour' in 'fetal bovine serum; 1 percent' | growth condition, time | Transcriptomic changes in C3H10T1/2 cells exposed to lipid deprivation |
1.2 | | Lif | 'K14-Cre-ERT2 / CK1α fl/fl; 4-hydroxytamoxifen; none; 14 day' vs 'K14-Cre-ERT2; none; none' | genotype, irradiate, time | Ablation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin |
1.2 | | Lif | 'interleukin-28A; 1000 nanogram per milliliter' vs 'none' | compound | Transcription profiling by high throughput sequencing of murine small intestinal epithelial cells stimulated with interleukin-28A |
1.2 | | Lif | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
1.2 | | Lif | 'CD36 knockout' vs 'wild type genotype' in 'none' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
1.2 | | Lif | 'hyperoxia' vs 'control' in 'male' | sex, stimulus | Transcription profiling by array of lung tissues from wild-type male and female C56BL/6J mice either maintained in room air or exposed to hyperoxia (FiO2>95%) for 48 hours |
1.2 | | Lif | 'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.2 | | Lif | '6 hour' vs '1 hour' in 'fetal bovine serum; 10 percent' | growth condition, time | Transcriptomic changes in C3H10T1/2 cells exposed to lipid deprivation |
1.2 | | Lif | '2 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
1.2 | | Lif | 'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector' | genotype | RNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice |
1.2 | | Lif | 'colitis' at '12 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
1.2 | | Lif | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.2 | | Lif | 'co-culture' vs 'separate' in 'wild type genotype' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
1.1 | | Lif | 'Cd1d homozyous knockout' vs 'wild type genotype' in 'α-GalCer; 2 microgram' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
1.1 | | Lif | 'interferon gamma; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1.1 | | Lif | 'induce erythroid differentiation' vs 'none' in 'wild type' | genotype, stimulus | Transcription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor |
-1.1 | | Lif | '3 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-1.1 | | Lif | 'osteoblast culture 9 day' vs '0 day' | time | Transcription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation |
-1.1 | | Lif | 'Runx1 knockdown; none' vs 'wild type; none' | genotype, stimulus | Transcription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor |
1.1 | | Lif | '5 nanogram per milliliter; TGFbeta1' vs 'none' at '24 hour' | compound, time | Transcription profiling by array of mouse hepatocytes following treatment with growth factor beta 1 in a time series |
1.1 | | Lif | 'recombinant human interleukin-2; 100 unit per milliliter; 12 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
1.1 | | Lif | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.1 | | Lif | 'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '12 month' | age, genotype | ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression] |
1.1 | | Lif | 'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
1.1 | | Lif | 'colitis' at '19 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
1.1 | | Lif | 'Kras G12D' vs 'wild type' | genotype | Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells |
-1.1 | | Lif | 'epithelial cell; E2' vs 'epithelial cell; vehicle' | cell type, treatment | Affymetrix gene chip analysis for the whole mouse genome transcripts of epithelial and stromal cells from mouse uterine primary co-culture treated with either vehicle or E2 |
1.1 | | Lif | 'Lin- CD44+ CD25+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44+ CD25+ thymocyte progenitor cell; adult' | cell type, developmental stage | Transcription profiling of mouse adult and fetal T cell progenitors |
1.1 | | Lif | 'Ffar3 knockout' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of pancreatic islets isolated from free fatty acid receptor 3 knockout (Ffar3 KO) and wild type (Ffar3 WT) male mice |
1.1 | | Lif | 'co-culture' vs 'separate' in 'Ink4a/Arf-/-; EGFRvIII' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
1.1 | | Lif | 'Hnf4a-pKO;Hnf1aHET double mutant' vs 'wild type genotype' | genotype | Transcription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice |
-1 | | Lif | 'MG132; 1 micromolar' vs 'DMSO' in 'wild type' | compound, genotype | Microarray to find ATF5 dependent genes in response to proteasome inhibition |
1 | | Lif | 'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1 | | Lif | 'IRAK1BP1 KO' vs 'wild type' in 'TNFα' | genotype, treatment | Identification of TNFα-induced genes that are IRAK1BP1 dependent |
1 | | Lif | 'Lactobacillus acidophilus NCFM and Bifidobacterium bifidum Z9' vs 'control' | infect | Transcription profiling by array of mouse dendritic cells after infection with Bifidobacterium bifidum and Lactobacillus acidophilus |
-1 | | Lif | 'pkd1 knockout' vs 'wild type' in 'presence of fluid flow' | genotype, stimulus | Transcription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow |
1 | | Lif | 'Mettl6 knockout clone D1' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
1 | | Lif | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Lif | 'Foxd3 knockout' vs 'control' | phenotype | Expression data from embryonic stem cells differentiation |
1 | | Lif | 'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1 | | Lif | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram; Plasmodium berghei ANKA; 7 day' vs 'none; none; 0 day' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1 | | Lif | '144 hour after induction of differentiation' vs 'induction of differentiation' | compound, sampling time point | Expression Profiling of Early Myogenesis - Affymetrix Dataset |
1 | | Lif | '4 week' vs '0 week' | time | Transcription profiling by array of mouse colon tissues with T cell transfer-induced colitis at week 0, 2, 4 and 6 post-transfer |
-1 | | Lif | 'STAT5 double knocked in' vs 'wild type' in 'interleukin-2' at '6 hour' | compound, genotype, time | Gene expression profile of splenic T cells from STAT5 double knocked in mice treated with IL-2 |
1 | | Lif | '96 hour after induction of differentiation' vs 'induction of differentiation' | compound, sampling time point | Expression Profiling of Early Myogenesis - Affymetrix Dataset |
1 | | Lif | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
1 | | Lif | 'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; adult' | cell type, developmental stage | Transcription profiling of mouse adult and fetal T cell progenitors |
1 | | Lif | 'Adjuvant System 03' vs 'PBS' in 'hindlimb muscle' at '4 hour' | organism part, stimulus, time | Expression data from draining lymph node and muscle of mice immunised with AS03 or PBS |
1 | | Lif | '3 hour' vs '1 hour' in 'fetal bovine serum; 10 percent' | growth condition, time | Transcriptomic changes in C3H10T1/2 cells exposed to lipid deprivation |
-1 | | Lif | 'AhCre Cited1 knockout' vs 'control' | genotype | Cited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis |
-1 | | Lif | 'STAT5 double knocked in' vs 'wild type' in 'interleukin-2' at '2 hour' | compound, genotype, time | Gene expression profile of splenic T cells from STAT5 double knocked in mice treated with IL-2 |
1 | | Lif | 'interleukin-36 alpha and beta and gamma' vs 'none' | stimulus | Transcriptional profiling of long-term stimulated primary murine intestinal fibroblasts with interleukin-36. |
1 | | Lif | 'ATF3 -/-' vs 'wild type' in '10 nanogram per milliliter; lipopolysaccharide' at '2 hour' | compound, genotype, time | Transcription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide |
-1 | | Lif | 'pre-B acute lymphoblastic leukemia Bin2; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia Bin2; nilotinib; 0 day' | cell type, compound, time | Drug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs |
1 | | Lif | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Lif | 'Influenza A virus' vs 'none' | infect | RNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals |
-1 | | Lif | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
1 | | Lif | 'fetal bovine serum; 10 percent' vs 'fetal bovine serum; 1 percent' at '3 hour' | growth condition, time | Transcriptomic changes in C3H10T1/2 cells exposed to lipid deprivation |
1 | | Lif | 'Macrophage of F4/80+, CD11b+, CD11c-; obese leptin-deficient' vs 'Macrophage of F4/80+, CD11b+, CD11c-; control' | cell type, genotype | Expression data from mouse adipose tissue macrophage |
1 | | Lif | 'adult exposure to second-hand smoke' vs 'adult exposure to air' in 'in utero exposure to air' | environmental stress, growth condition | Expression data from mouse lungs exposed in-utero and/or as an adult to second-hand smoke (SHS) |
1 | | Lif | 'smoke; 1500 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |