-7.8 | | Rasd2 | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-7.3 | | Rasd2 | 'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
5.9 | | Rasd2 | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
5.2 | | Rasd2 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-5 | | Rasd2 | 'SMRT shRNA' vs 'none' in 'none' at '0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
4.9 | | Rasd2 | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
4.7 | | Rasd2 | 'neuronal stem cell; positive staining for GFP and prominin' vs 'astrocyte; positive staining for GFP' | cell type, phenotype | Transcription profiling by array of adult neural stem cells (hGFAP-GFP+/prominin1+ cells) compared to parenchymal astrocytes that are not neurogenic (hGFAP-GFP+ cells from the diencephalon) |
-4.4 | | Rasd2 | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
4 | | Rasd2 | 'Albumin Cre+/-;Hnf4a fl/fl' vs 'wild type genotype' | genotype | Transcription profiling by array of liver-specific Hnf4alpha knock-out mice |
-4 | | Rasd2 | 'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-3.7 | | Rasd2 | 'CpG; 6 hour' vs 'none; 0 hour' in 'none' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
3.6 | | Rasd2 | "muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP negative" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
-3.6 | | Rasd2 | 'SMRT shRNA' vs 'none' in 'CpG' at '6 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-3.6 | | Rasd2 | 'clear cell sarcoma; Rosa26CreER' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-3.5 | | Rasd2 | 'RA839; Nrf2 knockout' vs 'RA839; wild type genotype' | RNA interference, compound, genotype | Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling |
-3.4 | | Rasd2 | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-3.4 | | Rasd2 | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
3.3 | | Rasd2 | 'Abcc8-/-' vs 'wild type genotype' in 'normal; female' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
3.2 | | Rasd2 | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
3.2 | | Rasd2 | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
3.1 | | Rasd2 | 'AAV9-Ccnt1;Myh6-cre;LSL-R26CAG-c-MycERT2/+' vs 'AAV9-Ccnt1;LSL-R26CAG-c-MycERT2/+' | genotype | RNA-seq of purified cardiomocytes from adult mice (+/- AAV-CCNT1) 4 hours post MycER activation compared controls. |
3.1 | | Rasd2 | 'c-Myc activation' vs 'wild type' | phenotype | RNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls. |
-3.1 | | Rasd2 | 'lung carcinoma' vs 'normal' in 'lung cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-3 | | Rasd2 | 'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
-3 | | Rasd2 | 'neuron' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
2.8 | | Rasd2 | 'wild type genoytpe; siRNA Keap1-2' vs 'wild type genotype; scrambled shRNA' | RNA interference, compound, genotype | Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling |
2.7 | | Rasd2 | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
2.6 | | Rasd2 | 'Cnot3 knockout' vs 'wild type' | phenotype | RNA-seq of mouse islets from Ins1-cre driven Cnot3 KO and control islets |
-2.6 | | Rasd2 | 'Debaryomyces hansenii' at '24 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
2.6 | | Rasd2 | 'H-Ras expression; c-Myc activation' vs 'wild type' | phenotype | RNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls. |
2.6 | | Rasd2 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
2.6 | | Rasd2 | 'wild type genoytpe; siRNA Keap1-1' vs 'wild type genotype; scrambled shRNA' | RNA interference, compound, genotype | Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling |
-2.5 | | Rasd2 | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-2.5 | | Rasd2 | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
2.5 | | Rasd2 | 'AZD7507; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-2.5 | | Rasd2 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
2.4 | | Rasd2 | 'Abcc8 knockout' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of pancreatic beta cells from wild type and Abcc8 knockout mice |
2.4 | | Rasd2 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
2.4 | | Rasd2 | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
-2.3 | | Rasd2 | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-2.3 | | Rasd2 | 'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
2.3 | | Rasd2 | 'carboplatin; 30 milligram per kilogram' vs 'none' in '14 week; none' | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
2.2 | | Rasd2 | 'Abcc8-/-' vs 'wild type genotype' in 'high fat; female' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
2.2 | | Rasd2 | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
2.2 | | Rasd2 | "muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP positive" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
2.2 | | Rasd2 | 'normal skin; PKC alpha-/-' vs 'normal skin; wild type genotype' | clinical history, genotype | Altered dermal architecture in PKCα-/- skin |
2.2 | | Rasd2 | 'RA839; wild type genotype' vs 'vehicle control; wild type genotype' | RNA interference, compound, genotype | Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling |
2.2 | | Rasd2 | 'soticlestat; 30 milligram per kilogram' vs 'none' in 'astrocyte; none' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
2.2 | | Rasd2 | 'spontaneous lung tumor' vs 'normal' | disease state, disease | Transcription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer |
2.2 | | Rasd2 | 'liver-specific Cnot3 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
-2.2 | | Rasd2 | 'Runx3 knockout' vs 'wild type genotype' in 'IL-2' | compound, genotype | Runx3 function in splenic NK cells (IL-2 or IL-15) |
-2.2 | | Rasd2 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-2.2 | | Rasd2 | 'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.1 | | Rasd2 | 'AMPK double knockout; floxed AMPK alpha 1 and 2 with Ins1-Cre' vs 'floxed AMPK without Ins1-Cre; wild type' | genotype, phenotype | Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice |
2.1 | | Rasd2 | 'Lmp7-/-Mecl1-/-' vs 'wild type' | genotype | Effect of LMP7 and MECL1-immunoproteasome subunits deficiency on the transcriptome of mouse bone marrow-derived dendritic cells |
2.1 | | Rasd2 | 'Abcc8-/-' vs 'wild type genotype' in 'normal; male' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
-2.1 | | Rasd2 | 'R6/2 transgenic' vs 'wild type' in '12 week; striatum' | age, genotype, organism part | Transcription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks. |
-2.1 | | Rasd2 | 'carotid body' vs 'adrenal medulla' | organism part | Expression profile of mouse carotid body and adrenal medulla [RNA-Seq] |
2.1 | | Rasd2 | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
-2.1 | | Rasd2 | 'synovial sarcoma' vs 'normal' | disease | Transcription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice |
-2 | | Rasd2 | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
-2 | | Rasd2 | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
2 | | Rasd2 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-2 | | Rasd2 | 'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
1.9 | | Rasd2 | 'Ffar3 knockout' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of pancreatic islets isolated from free fatty acid receptor 3 knockout (Ffar3 KO) and wild type (Ffar3 WT) male mice |
-1.9 | | Rasd2 | 'Lkb1 -/- Pten-/-' vs 'wild type' | genotype | Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells |
-1.9 | | Rasd2 | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Transcription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa |
-1.9 | | Rasd2 | 'status epilepticus' vs 'none' in 'astrocyte; soticlestat; 30 milligram per kilogram' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
-1.8 | | Rasd2 | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
-1.8 | | Rasd2 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.8 | | Rasd2 | 'dexamethasone; 1 micromolar' vs 'none' | compound | RNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS |
1.8 | | Rasd2 | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
-1.8 | | Rasd2 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.8 | | Rasd2 | 'transgenic humanSODG93A' vs 'wild type' in 'gastrocnemius' | clinical treatment, genotype, organism part | Gene expression profiling of muscles from transgenic humanSODG93A mice at symptomatic stage |
-1.7 | | Rasd2 | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
1.7 | | Rasd2 | 'MeCP2TG' vs 'wild type' | genotype | Expression data of Myh6-MeCP2 transgenic mice |
-1.7 | | Rasd2 | 'sciatic nerves at the midtight level crushed by compression' vs 'none' in 'wild type; gastrocnemius' | clinical treatment, genotype, organism part | Gene expression profiling of muscles from transgenic humanSODG93A mice at symptomatic stage |
1.7 | | Rasd2 | 'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'separate' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
-1.7 | | Rasd2 | 'cSix1 KO' vs 'wild type' | genotype | Six homeoproteins and a linc-RNA cooperate at the fast MYH locus to lock terminal fast myofibre phenotype |
-1.7 | | Rasd2 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1.7 | | Rasd2 | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'inguinal fat pad' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
1.6 | | Rasd2 | 'anti-CD3/CSA' vs 'anti-CD3' in 'cyclosporine-sensitive' | phenotype, treatment | Activating CD8 T cell clones via the T cell receptor complex in the absence and presence of cyclosporine A |
-1.6 | | Rasd2 | 'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-1.6 | | Rasd2 | 'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1.6 | | Rasd2 | 'epithelium-specific mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1.6 | | Rasd2 | 'Notch 1 and 2 null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
1.6 | | Rasd2 | '1810027O10Rik knockout; gonad adipose tissue' vs 'wild type genotype; gonad adipose tissue' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
-1.6 | | Rasd2 | 'AMPK double knockout; floxed AMPK alpha 1 and 2 with RIP-Cre' vs 'floxed AMPK without RIP-Cre; wild type' | genotype, phenotype | Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice |
1.6 | | Rasd2 | 'BAG6 homozygous knockout' vs 'wild type genotype' | genotype | Transcription profiling of B16V mouse melanoma cells after BAG6 knockout to study impacts on extracellular vesicle mRNA cargo |
-1.6 | | Rasd2 | 'dexamethasone (1 μM) and GW7647 (0.5 μM)' vs 'none' | compound | RNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS |
-1.6 | | Rasd2 | '6 day' vs '0 day' | time | Transcription profiling by array of mouse colon tissues under dextran sodium sulphate induction for 2, 4 and 6 days against uninduced controls at day 0 |
1.6 | | Rasd2 | 'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
1.5 | | Rasd2 | 'Mettl6 knockout clone D1' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
-1.5 | | Rasd2 | 'induced neuronal cell' vs 'pluripotent embryonic stem cell' | phenotype | Transcription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells |
-1.5 | | Rasd2 | 'Drosha -/-' vs 'wild type genotype' | genotype | RNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs |
-1.5 | | Rasd2 | 'tamoxifen; autosomal dominant polycystic kidney disease' vs 'none; normal' | compound, disease, time | Expression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC |
-1.5 | | Rasd2 | 'LKB1 knockout; floxed LKB1 with RIP-Cre' vs 'floxed LKB1 without RIP-Cre; wild type' | genotype, phenotype | Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice |
-1.5 | | Rasd2 | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
-1.5 | | Rasd2 | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-1.5 | | Rasd2 | 'dextran sodium sulfate' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion |
-1.5 | | Rasd2 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.5 | | Rasd2 | 'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
1.5 | | Rasd2 | 'interferon gamma; 1 nanogram per milliliter' vs 'none' | stimulus | Analysis of transcriptomes in intestinal stem cells in response to Interferon gamma |
1.4 | | Rasd2 | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
-1.4 | | Rasd2 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.4 | | Rasd2 | 'seizure-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle' | clinical treatment | Transcription profiling by array of mice with epileptic tolerance |
-1.4 | | Rasd2 | 'PGC-1 beta knock in' vs 'wild type' | genotype | Transcription profiling by array of skeletal muscle from PGC-1 beta transgenic mice |
1.4 | | Rasd2 | 'Aire knockout' vs 'wild type' in 'cTEC' | genotype, phenotype | Transcription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice |
-1.4 | | Rasd2 | 'acute DSS-induced colitis; 1x DSS, no recovery' vs 'none; none' | clinical treatment, disease | Transcription profiling by array of colon tissues isolated from mice with acute and chronic dextran sodium sulphate (DSS)-induced colitis |
-1.4 | | Rasd2 | 'proliferating progenitor' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
-1.4 | | Rasd2 | 'ductus arteriosis' vs 'aorta' | organism part | Gene Profiling in Mouse Fetal Ductus Arteriosus |
1.3 | | Rasd2 | 'high fat' vs 'normal' in 'wild type genotype; female' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
-1.3 | | Rasd2 | 'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype' | genotype | Transcription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy |
1.3 | | Rasd2 | 'transgenic hepatic growth hormone' vs 'wild type genotype' in '12 week' | age, genotype | Hepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice |
-1.3 | | Rasd2 | 'Xist-/-' vs 'wild type genotype' in 'gastrointestinal polyp' | genotype, organism part | RNA-seq of Xist deletion mouse models |
-1.3 | | Rasd2 | 'Stat5abfl/fl;MMTV-Cre' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
-1.3 | | Rasd2 | 'SARS coronavirus MA15' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1.3 | | Rasd2 | 'vehicle control; Nrf2 knockout' vs 'vehicle control; wild type genotype' | RNA interference, compound, genotype | Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling |
-1.3 | | Rasd2 | 'ulcer' vs 'distant normal tissue' in 'Bmp4 overexpression' | genotype, sampling site, time | Intestinal ulcers from biopsy-wounded wild-type and Bmp4-overexpressing mice |
-1.3 | | Rasd2 | 'Mycobacterium tuberculosis H37Rv' vs 'none' | infect | The global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice |
1.3 | | Rasd2 | 'stabilization-competent' vs 'stabilization-incompetent' in '27 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
-1.3 | | Rasd2 | 'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
-1.3 | | Rasd2 | 'recombinant human interleukin-2; 100 unit per milliliter; 2 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
1.3 | | Rasd2 | 'high fat diet' vs 'normal' in 'wild type' | diet, genotype | Transcription profiling by array of pancreatic islets from Sgpp2 knockout mice after high fat diet |
1.2 | | Rasd2 | 'high fat' vs 'normal' in 'wild type genotype; male' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
-1.2 | | Rasd2 | '6 week' vs '0 week' | time | Transcription profiling by array of mouse colon tissues with T cell transfer-induced colitis at week 0, 2, 4 and 6 post-transfer |
-1.2 | | Rasd2 | 'PR knockout' vs 'control' | genotype | Expression data from progesterone receptor knockout versus heterozygous mouse oviducts |
1.2 | | Rasd2 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-1.2 | | Rasd2 | 'Yin Yang 1 (YY1) knockout' vs 'wild type' | genotype | Expression data from mouse skeletal muscle |
1.2 | | Rasd2 | 'V6.5; embryonic stem cell’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
-1.2 | | Rasd2 | 'organoid culture without Noggin (ER medium)' vs 'organoid culture (ENR medium)' in 'intestinal smooth muscle culture supernatant' | growth condition, stimulus | RNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant |
-1.2 | | Rasd2 | 'Adjuvant System 03' vs 'PBS' in 'lymph node' at '6 hour' | organism part, stimulus, time | Expression data from draining lymph node and muscle of mice immunised with AS03 or PBS |
-1.2 | | Rasd2 | 'masseter muscle' vs 'tibialis anterior' | organism part | Transcription profiling of mouse masseter and tibialis anterior muscles to determine expression differences between muscle groups |
1.2 | | Rasd2 | 'doxycycline; 200 nanogram per milliliter; neoplasm; 12 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.2 | | Rasd2 | 'co-culture' vs 'separate' in 'Ink4a/Arf-/-; EGFRvIII' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
1.2 | | Rasd2 | 'damaged by neuropathy' vs 'control' | sampling site | Transcriptional profiling of damaged and adjacent but intact dorsal root ganglia neurons against DRG cells from contralacteral control regions from mice with neuropathy |
-1.2 | | Rasd2 | 'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
1.1 | | Rasd2 | 'Mettl6 knockout clone G6' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
-1.1 | | Rasd2 | 'Zbtb2 -/-' vs 'wild type genotype' in 'EpiLC' at '2 day' | genotype, growth condition, time | RNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions. |
1.1 | | Rasd2 | 'IL17A homozygous knockout' vs 'wild type genotype' in 'ascending colon' | genotype, organism part | RNAseq analysis of colon and ileum tissue from naive wild type, MR1-/- and IL-17A-/- mice |
1.1 | | Rasd2 | 'shear stressing' vs 'none' | stimulus | RNA seq of fluid shear stress treated mouse Pkd1-/- renal epithelial cells |
-1.1 | | Rasd2 | 'epithelium-specific Bcl9; Bcl9l knockout and mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-1.1 | | Rasd2 | 'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day' | compound, genotype, time | Transcription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin |
1.1 | | Rasd2 | 'AZD8835; 50 milligram per kilogram' vs 'none' at '14 day' | compound, time | RNAseq of tumor samples from CT26 syngeneic mouse treated with a PI3Ka/d inhibitor (AZD8835) |
-1.1 | | Rasd2 | 'AhCre Apc Floxed Cited1 knockout' vs 'control' | genotype | Cited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis |
-1.1 | | Rasd2 | 'Influenza A virus (A/Scotland/20/1974(H3N2))' vs 'none' | infect | RNA-seq of mouse colon to investigate how influenza infection leads to intestinal disorders |
1.1 | | Rasd2 | 'Hnf1a knock out' vs 'wild type' | genotype | Transcription profiling of pancreatic islets from Hnf1a-deficient and wild type mice |
-1.1 | | Rasd2 | 'AhCre Apc Floxed' vs 'control' | genotype | Cited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis |
-1.1 | | Rasd2 | 'SARS coronavirus MA15 E protein mutant Δ5' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1.1 | | Rasd2 | 'SARS coronavirus MA15; 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.1 | | Rasd2 | 'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
1.1 | | Rasd2 | 'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype' | genotype | Antibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq |
1.1 | | Rasd2 | 'Bmi1-overexpressing lentiviral vector' vs 'empty vector control' | genotype | Control and Bmi1-overexpressing adult murine neural stem cells |
1 | | Rasd2 | 'Trim24 knockdown' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of mouse embryonic stem cells following Trim24 and/or p53 knockdown |
1 | | Rasd2 | 'Trim24,Trp53 double knockdown' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of mouse embryonic stem cells following Trim24 and/or p53 knockdown |
1 | | Rasd2 | '2 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-1 | | Rasd2 | 'Med1 knockout' vs 'wild type' in 'lateral prostate' | genotype, organism part | Changes in gene expression caused by loss of Med1 in the mouse prostate |
-1 | | Rasd2 | 'colitis' at '12 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-1 | | Rasd2 | '4 week' vs '0 week' | time | Transcription profiling by array of mouse colon tissues with T cell transfer-induced colitis at week 0, 2, 4 and 6 post-transfer |
-1 | | Rasd2 | 'missense mutation (T2996C) in Mucin 2 (Muc2)' vs 'wild type genotype' | genotype | Transcription profiling of mouse intestine in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress |
-1 | | Rasd2 | 'interferon gamma; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1 | | Rasd2 | 'mock inoculated' at '150 day' vs 'none' at '0 day' | infect, time | Transcription profiling by array of brains from mice infected with scrapie ME7 |
1 | | Rasd2 | 'Dcrfx/fx;MisCre' vs 'wild type' in '5 day' | age, genotype | Transcription profiling of testis from wild type mice and mice with a Sertoli-specific ablation of Dicer |
-1 | | Rasd2 | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1 | | Rasd2 | 'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
1 | | Rasd2 | '25 month, normal diet' vs '5 month, normal diet' | age, diet | Transcription profiling of skeletal muscles from young, old, and old calorie restricted C57BL/6NHsd mice to investigate age-related changes in the transcriptional profile |
-1 | | Rasd2 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Rasd2 | 'dominant-negative Brg1' vs 'wild type' | genotype | Transcription profiling by array of lens tissue from mice expressing a dnBrg1 transgenic construct |
-1 | | Rasd2 | 'none; ; CHIP knockout' vs 'none; ; wild type' | compound, genotype | Expression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5 |
1 | | Rasd2 | 'AZD8835; 50 milligram per kilogram' vs 'none' at '7 day' | compound, time | RNAseq of tumor samples from CT26 syngeneic mouse treated with a PI3Ka/d inhibitor (AZD8835) |
-1 | | Rasd2 | 'IEC-specific HDAC3 deletion' vs 'floxed HDAC3 (wild type)' | genotype | Transcription profiling by array of intestinal epithelial cells (IECs) in germ-free conditions from mice with IEC-specific HDAC3 deletion against wild type controls |