ENSMUSG00000037440 (Vnn1)

mus musculus

vanin 1

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Experimental variables
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
00
Log2-fold change
7.5
Vnn1'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
4.6834 × 10-125.5
Vnn1'neural progenitor cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
1.104 × 10-6-5.4
Vnn1'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
4.6526 × 10-13-5.2
Vnn1'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
6.2579 × 10-64.4
Vnn1'smoke; 3000 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
3.193 × 10-44.4
Vnn1'L-Pex5 knock-out' vs 'wild type'genotypeTranscription profiling by array of liver from L-Pex5 knock-out mice
Adjusted p-valueLog2-fold change
8.1674 × 10-1424.2
Vnn1'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
8.8411 × 10-6-4.1
Vnn1'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
3.4389 × 10-164
Vnn1'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.0488 × 10-54
Vnn1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
4.5061 × 10-5-4
Vnn1'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
1.2935 × 10-63.9
Vnn1'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
9.0507 × 10-273.8
Vnn1'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.8102 × 10-63.8
Vnn1'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
4.3577 × 10-53.8
Vnn1'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.2357 × 10-43.8
Vnn1'smoke; 1500 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
3.582 × 10-53.7
Vnn1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 15 days post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
3.5157 × 10-2-3.6
Vnn1'V6.5; embryonic stem cell’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
7.3766 × 10-63.5
Vnn1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 2 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
2.5843 × 10-43.5
Vnn1'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.3532 × 10-743.4
Vnn1'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.6278 × 10-8-3.4
Vnn1'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.2691 × 10-6-3.4
Vnn1'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
3.1238 × 10-63.4
Vnn1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 2 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.2909 × 10-53.4
Vnn1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
6.7343 × 10-53.4
Vnn1'p150 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA'RNA interferenceRNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells
Adjusted p-valueLog2-fold change
4.9678 × 10-33.4
Vnn1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 15 days post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.831 × 10-2-3.4
Vnn1'overexpression of SRC-2' vs 'control'phenotypeA pivotal role of SRC-2 in Metastatic and Castration Resistant Prostate Cancer
Adjusted p-valueLog2-fold change
4.1771 × 10-10-3.3
Vnn1'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'inguinal fat pad'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
1.3491 × 10-53.3
Vnn1'smoke; 1500 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
6.0147 × 10-33.3
Vnn1'neuronal stem cell; positive staining for GFP and prominin' vs 'astrocyte; positive staining for GFP'cell type, phenotypeTranscription profiling by array of adult neural stem cells (hGFAP-GFP+/prominin1+ cells) compared to parenchymal astrocytes that are not neurogenic (hGFAP-GFP+ cells from the diencephalon)
Adjusted p-valueLog2-fold change
1.6289 × 10-583.2
Vnn1'3D culture' vs '2D culture'growth conditionmRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture
Adjusted p-valueLog2-fold change
1.1358 × 10-503.2
Vnn1'intestinal smooth muscle culture supernatant' vs 'none' in 'organoid culture without Noggin (ER medium)'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
1.1418 × 10-53.2
Vnn1'smoke; 3000 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
2.0223 × 10-33.2
Vnn1'human fast food diet' vs 'control diet'dietTranscription profiling by array of mice fed on human cafeteria diet, human fast food diet, or chimpanzee diet
Adjusted p-valueLog2-fold change
3.2609 × 10-23.2
Vnn1'liver-specific Gp130 knockout mice [Gp130delta(hepa)]; cecal ligation and puncture' vs 'liver-specific Gp130 knockout mice [Gp130delta(hepa)]; control'genotype, treatmentHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Adjusted p-valueLog2-fold change
2.4046 × 10-193.1
Vnn1'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.601 × 10-53.1
Vnn1'high fat diet' vs 'regular chow diet' in 'wild type genotype'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
6.7138 × 10-53.1
Vnn1'smoke; 1500 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
8.9857 × 10-53.1
Vnn1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
2.5632 × 10-33.1
Vnn1'Er1F/-' vs 'wild type genotype'genotypeRNA-Seq profiling of ERCC1-XPF DNA repair defect (Er1F/-) versus wild type (Er1F/+) macrophages
Adjusted p-valueLog2-fold change
4.4497 × 10-12-3
Vnn1'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
8.4476 × 10-53
Vnn1'p48-Cre;KrasG12D;Ela-Tgfa' vs 'wild type'genotypeTranscription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice
Adjusted p-valueLog2-fold change
4.728 × 10-43
Vnn1'p60 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA'RNA interferenceRNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells
Adjusted p-valueLog2-fold change
6.4712 × 10-4-3
Vnn1'Lmna G609G/G609G knock in' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Lmna Gly609Gly knock in
Adjusted p-valueLog2-fold change
1.5982 × 10-602.9
Vnn1'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
8.4589 × 10-4-2.9
Vnn1'Nr4a1 Nr4a3 double knockout' vs 'wild type genotype'genotypeExpression data of mouse hematopoietic cells, Nr4a1/3 wild type and double mutant
Adjusted p-valueLog2-fold change
5.007 × 10-24-2.8
Vnn1'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
4.2049 × 10-122.8
Vnn1'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
3.4779 × 10-6-2.8
Vnn1'swimming exercised for 6 weeks' vs 'sedentary control'treatmentMicroarray results from atrial tissue isolated from 6-week swimming exercised mice compared to sedentary controls
Adjusted p-valueLog2-fold change
2.5639 × 10-32.8
Vnn1'chimpanzee diet' vs 'control diet'dietTranscription profiling by array of mice fed on human cafeteria diet, human fast food diet, or chimpanzee diet
Adjusted p-valueLog2-fold change
1.203 × 10-2-2.8
Vnn1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
5.0804 × 10-25-2.7
Vnn1'129S1 allele at SNP rs50454566' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene
Adjusted p-valueLog2-fold change
1.4766 × 10-82.7
Vnn1'perfluorooctanoic acid; 5 milligram per kilogram per day' vs 'none' in 'liver'block, compound, organism partTranscription profiling of lung and liver from low and high dose Perfluorooctanoic Acid exposed fetuses
Adjusted p-valueLog2-fold change
1.0727 × 10-52.7
Vnn1'hematopoietic stem cell and hematopoietic multipotent progenitor cell' vs 'common myeloid progenitor'cell typeTranscription profiling by high throughput sequencing between multipotent hematopoietic stem progenitor cells LS+K) and myeloid committed cells (LS−K) of the mouse bone marrow
Adjusted p-valueLog2-fold change
1.1255 × 10-42.7
Vnn1'smoke; 1500 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
3.117 × 10-4-2.7
Vnn1'wild type; mature luminal' vs 'wild type; MaSC/basal'cell type, genotypeExpression data from sorted control and Pygo2-null mouse mammary stem/basal cells
Adjusted p-valueLog2-fold change
5.8254 × 10-4-2.7
Vnn1'Hepatic RXR_alpha-Knockout' vs 'wild type' in 'RA-treated'genotype, treatmentGene expression data of untreated and RA-treated wild type and RXRα-deficient mice liver
Adjusted p-valueLog2-fold change
7.6917 × 10-3-2.7
Vnn1'Yin Yang 1 adipose tissue specific deletion' vs 'wild type phenotype'phenotypeBrown fat-specific YY1 deficiency effect on subcutaneous white adipose tissue
Adjusted p-valueLog2-fold change
4.9876 × 10-192.6
Vnn1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.5562 × 10-82.6
Vnn1'perfluorooctanoic acid; 3 milligram per kilogram per day' vs 'none' in 'liver'block, compound, organism partTranscription profiling of lung and liver from low and high dose Perfluorooctanoic Acid exposed fetuses
Adjusted p-valueLog2-fold change
3.3168 × 10-72.6
Vnn1'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
5.7168 × 10-52.6
Vnn1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
2.8005 × 10-32.6
Vnn1'Gata6 knockout' vs 'wild type'phenotypeGlobal gene expression in the adult Gata6 null mouse pancreas
Adjusted p-valueLog2-fold change
9.4232 × 10-3-2.6
Vnn1'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '12 month'age, genotypeErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression]
Adjusted p-valueLog2-fold change
1.6448 × 10-22.6
Vnn1'CAR deficient; ethanol and trans-resveratrol' vs 'wild type; ethanol and trans-resveratrol'genotype, treatmentNuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages
Adjusted p-valueLog2-fold change
1.7686 × 10-472.5
Vnn1'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
1.9339 × 10-82.5
Vnn1'5-aza-2'-deoxycytidine; 5 micromolar' vs 'none'compoundTranscription profiling by array of mouse primary dermal fibroblasts after treatment with 5-aza-2'-deoxycytidine
Adjusted p-valueLog2-fold change
5.9529 × 10-52.5
Vnn1'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
2.611 × 10-3-2.5
Vnn1'hypomorphic Cpr (Cpr low)' vs 'Cpr-lox control'genotypeTranscription profiling of mouse models with liver-specific deletion or global hypomorphic expression of the NADPH-cytochrome P450 reductase gene to study molecular mechanisms for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.
Adjusted p-valueLog2-fold change
2.8011 × 10-22.5
Vnn1'Ghrh-KO' vs 'wild type'genotypeGene expression in liver tissue from Ghrh-KO and normal (wild-type) mice
Adjusted p-valueLog2-fold change
4.1063 × 10-2-2.5
Vnn1'30 month' vs '5 month' in 'male'age, block, sexExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Adjusted p-valueLog2-fold change
1.4921 × 10-72.4
Vnn1'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.017 × 10-72.4
Vnn1'perfluorooctanoic acid; 10 milligram per kilogram per day' vs 'none' in 'liver'block, compound, organism partTranscription profiling of lung and liver from low and high dose Perfluorooctanoic Acid exposed fetuses
Adjusted p-valueLog2-fold change
6.5577 × 10-72.4
Vnn1'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.2005 × 10-5-2.4
Vnn1'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.4588 × 10-4-2.4
Vnn1'wild type; ethanol and trans-resveratrol' vs 'wild type; control'genotype, treatmentNuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages
Adjusted p-valueLog2-fold change
9.2276 × 10-32.4
Vnn1"Evi1-GFP positive" vs "Evi1-GFP negative"phenotypeWhole genome expression profiling of Evi1-GFP positive and negative murine hematopoietic stem cell sub-populations.
Adjusted p-valueLog2-fold change
1.3485 × 10-282.3
Vnn1'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.4917 × 10-9-2.3
Vnn1'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
2.0194 × 10-72.3
Vnn1'perfluorooctanoic acid; 1 milligram per kilogram per day' vs 'none' in 'liver'block, compound, organism partTranscription profiling of lung and liver from low and high dose Perfluorooctanoic Acid exposed fetuses
Adjusted p-valueLog2-fold change
2.2663 × 10-62.3
Vnn1'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
5.3936 × 10-62.3
Vnn1'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.5465 × 10-62.3
Vnn1'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
6.916 × 10-52.3
Vnn1'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
6.1596 × 10-392.2
Vnn1'9V/null' vs 'wild type' in 'saline; lung'compound, genotype, organism partGaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase [RNA-Seq]
Adjusted p-valueLog2-fold change
5.4873 × 10-182.2
Vnn1'high fat' vs 'chow' in 'NZO/HILtJ'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
2.1148 × 10-102.2
Vnn1'336 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
9.5571 × 10-102.2
Vnn1'fenofibrate diet' vs 'control diet'dietComparative transcriptomics and metabolomic analysis of fenofibrate and fish oil treatments in mice
Adjusted p-valueLog2-fold change
3.7602 × 10-8-2.2
Vnn1'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
6.0923 × 10-72.2
Vnn1'chronic cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
1.2104 × 10-52.2
Vnn1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
4.2261 × 10-52.2
Vnn1'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
4.8308 × 10-322.1
Vnn1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.4875 × 10-92.1
Vnn1'6 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
2.0732 × 10-72.1
Vnn1'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
4.8237 × 10-62.1
Vnn1'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.1027 × 10-5-2.1
Vnn1'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.1004 × 10-42.1
Vnn1'high fat diet' vs 'regular chow diet' in 'liver-specific Pit1 knockout'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
6.806 × 10-42.1
Vnn1'upf3 knockout' vs 'wild type' in 'testis'cell type, genotypeUPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs
Adjusted p-valueLog2-fold change
6.1944 × 10-3-2.1
Vnn1'6 month; RXRa hepatic deficiency; male' vs '6 month; wild type; male'age, genotype, sexTranscription profiling of liver from wild type and RXR-alpha deficient matured and aged mcie
Adjusted p-valueLog2-fold change
3.1523 × 10-22.1
Vnn1'human cafeteria diet' vs 'control diet'dietTranscription profiling by array of mice fed on human cafeteria diet, human fast food diet, or chimpanzee diet
Adjusted p-valueLog2-fold change
1.6306 × 10-22-2
Vnn1'15 degree celsius' vs '20 to 22 degree celsius' in 'Adrb1, Adrb2 and Adrb3 knockout'genotype, temperatureRNA-seq of cold-induced transcriptome changes in subcutaneous adipose tissue of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
2.7768 × 10-82
Vnn1'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
4.2621 × 10-42
Vnn1'overexpression of CA-NFATc3' vs 'control'phenotypeExpression data from embryonic stem cells differentiation
Adjusted p-valueLog2-fold change
3.2609 × 10-2-2
Vnn1'Kaiso knockout' vs 'wild type phenotype'phenotypeGene expression microarray analysis of whole intestine from Kaiso-/- mice
Adjusted p-valueLog2-fold change
4.634 × 10-25-1.9
Vnn1'dexamethasone; 1 micromolar' vs 'none'compoundRNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS
Adjusted p-valueLog2-fold change
1.5684 × 10-231.9
Vnn1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.9276 × 10-161.9
Vnn1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.1374 × 10-61.9
Vnn1'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 70 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
3.8583 × 10-51.9
Vnn1'Gabpa miRNA' vs 'control miRNA' in 'wild type genotype; fasted'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.0097 × 10-4-1.9
Vnn1'missense mutation (T2996C) in Mucin 2 (Muc2)' vs 'wild type genotype'genotypeTranscription profiling of mouse intestine in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
Adjusted p-valueLog2-fold change
1.8592 × 10-41.9
Vnn1'IEC-specific HDAC3 deletion' vs 'floxed HDAC3 (wild type)'genotypeTranscription profiling by array of intestinal epithelial cells (IECs) in germ-free conditions from mice with IEC-specific HDAC3 deletion against wild type controls
Adjusted p-valueLog2-fold change
4.5845 × 10-41.9
Vnn1'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.1019 × 10-31.9
Vnn1'spontaneous lung tumor' vs 'normal'disease state, diseaseTranscription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer
Adjusted p-valueLog2-fold change
1.2247 × 10-31.9
Vnn1'Sendai virus infected' vs 'UV-inactivated Sendai virus infected'infectAirway Epithelial Cell Response to Sendai virus infection
Adjusted p-valueLog2-fold change
3.2567 × 10-3-1.9
Vnn1'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; adult'cell type, developmental stageTranscription profiling of mouse adult and fetal T cell progenitors
Adjusted p-valueLog2-fold change
3.4052 × 10-31.9
Vnn1'CD2314 and BIO' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
4.2438 × 10-3-1.9
Vnn1'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
1.0111 × 10-2-1.9
Vnn1'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
1.1529 × 10-2-1.9
Vnn1'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
3.0885 × 10-21.9
Vnn1'Yin Yang 1 adipose tissue specific deletion' vs 'wild type phenotype'phenotypeBrown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity [IWAT]
Adjusted p-valueLog2-fold change
2.1058 × 10-1711.8
Vnn1'Miz1 siRNA' vs 'non-targeting siRNA'RNA interferenceRNA-SEQ analysis of KMC murine pancreatic ductal adenocarcinoma (PDAC) cell line upon siRNA depletion of MYC, KRas or Miz1 (aka Zbtb17)
Adjusted p-valueLog2-fold change
1.9374 × 10-121.8
Vnn1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.9234 × 10-91.8
Vnn1'trans-tympanically injected with Hemophilus influenza' vs 'control'treatmentOtitis Media Impact on Middle Ear
Adjusted p-valueLog2-fold change
8.4588 × 10-9-1.8
Vnn1'Ngn3-expressing cell' vs 'Ngn3-null cell'cell typeTranscriptional profiling of Ngn3-dependent pancreatic endocrine differentiation at E15.5
Adjusted p-valueLog2-fold change
1.0117 × 10-81.8
Vnn1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.4265 × 10-61.8
Vnn1'osteoblast culture 9 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
1.2355 × 10-51.8
Vnn1'Mycobacterium tuberculosis; DBA/2J congenic; 30 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
3.3364 × 10-51.8
Vnn1'Ela-Tgfa' vs 'wild type'genotypeTranscription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice
Adjusted p-valueLog2-fold change
2.1591 × 10-4-1.8
Vnn1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
2.5056 × 10-41.8
Vnn1'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.7619 × 10-4-1.8
Vnn1'5 nanogram per milliliter; TGFbeta1' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse hepatocytes following treatment with growth factor beta 1 in a time series
Adjusted p-valueLog2-fold change
4.191 × 10-31.8
Vnn1'K-ras mutant/Wt1-null' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
2.415 × 10-2-1.8
Vnn1'aire knock out' vs 'wild type'genotypeTranscription profiling by array of mice mutant for aire
Adjusted p-valueLog2-fold change
4.5885 × 10-21.8
Vnn1'BIO' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
4.9186 × 10-28-1.7
Vnn1'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
2.9238 × 10-17-1.7
Vnn1'Adrb1, Adrb2 and Adrb3 knockout' vs 'wild type genotype' in '15 degree celsius'genotype, temperatureRNA-seq of cold-induced transcriptome changes in subcutaneous adipose tissue of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
1.4273 × 10-10-1.7
Vnn1'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.8404 × 10-101.7
Vnn1'intestinal smooth muscle culture supernatant' vs 'none' in 'organoid culture (ENR medium)'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
1.8221 × 10-81.7
Vnn1'Stat5abfl/fl;MMTV-Cre' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
4.2872 × 10-61.7
Vnn1'Apc and Msx1 knockout in Villin1 positive cells' vs 'wild type'phenotypeTranscription profiling by array of Apc-deficient proximal colonic epithelium upon Msx1 transcription factor depletion
Adjusted p-valueLog2-fold change
4.3414 × 10-61.7
Vnn1'336 hour' vs '0 hour' on 'Affymetrix MOE430B Array'timeTranscription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
3.22 × 10-51.7
Vnn1'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 30 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.9803 × 10-4-1.7
Vnn1'beta(3)-adrenergic agonist Cl316,243' vs 'none' at '10 week'age, stimulusRNA-seq of age-associated transcriptome changes in brown adipose tissue
Adjusted p-valueLog2-fold change
3.1282 × 10-4-1.7
Vnn1'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
9.9459 × 10-41.7
Vnn1'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.7072 × 10-31.7
Vnn1'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.2888 × 10-2-1.7
Vnn1'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.0883 × 10-2-1.7
Vnn1'Pcl2 knockdown' vs 'control'genotypeGene expression profile in mouse embryonic stem cells in which endogenous Pcl2 expression was stably knocked down using short hairpin RNA
Adjusted p-valueLog2-fold change
1.2285 × 10-42-1.6
Vnn1'CEBPa K159Q/K298Q expression' vs 'wild type CEBPa expression'genotypeTranscriptome profiling of wild type, K159/298Q- and K159/298R- C/EBPα expressing mouse cells
Adjusted p-valueLog2-fold change
3.8061 × 10-101.6
Vnn1'Mycobacterium tuberculosis H37Rv' vs 'none' in 'wild type'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
8.3946 × 10-9-1.6
Vnn1'PPARalpha knockout' vs 'wild type genotype' in 'diet with PPAR-alpha ligand WY14,643'diet, genotypeTranscription profiling of mouse small intestine from wild-type (129S1/SvImJ) and PPAR-alpha-null (129S4/SvJae) animals treated with the synthetic PPAR-alpha ligand WY14,643 (0.1% w/w) for 5 days
Adjusted p-valueLog2-fold change
3.8674 × 10-81.6
Vnn1'5 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.1356 × 10-71.6
Vnn1'336 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
4.3455 × 10-71.6
Vnn1'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.9924 × 10-7-1.6
Vnn1'CHOP-/-' vs 'wild type' in 'DMSO'compound, genotypeMicroarray to find CHOP dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
2.6828 × 10-6-1.6
Vnn1'Aire knock out' vs 'wild type'genotypeTranscription profiling by array of mouse thymic medullary epithelial cells mutant for Aire
Adjusted p-valueLog2-fold change
6.7623 × 10-6-1.6
Vnn1'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.3182 × 10-5-1.6
Vnn1'TGF-beta; 15 nanogram per milliliter' vs 'control'compoundTGF beta Dosage Experiment
Adjusted p-valueLog2-fold change
2.6952 × 10-41.6
Vnn1'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
6.2423 × 10-41.6
Vnn1'Crx knockout' vs 'control' at '6 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
8.5304 × 10-31.6
Vnn1'PgrCre/+ Foxa2flox/flox' vs 'wild type'genotypeIdentification of candidate FOXA2-regulated genes in the adult mouse uterus
Adjusted p-valueLog2-fold change
1.1264 × 10-2-1.6
Vnn1'wild type; ethanol' vs 'wild type; control'genotype, treatmentNuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages
Adjusted p-valueLog2-fold change
1.2718 × 10-2-1.6
Vnn1'hematopoietic stem cell; FoxO1/3/4 triple knockout' vs 'hematopoietic stem cell; wild type genotype'cell type, genotypeTranscription profiling of bone marrow hematopoietic stem cells and myeloid progenitors from mice with conditional deletion of Forkhead O (FoxO) family of transcription factors
Adjusted p-valueLog2-fold change
4.569 × 10-2-1.6
Vnn1'undernutrition during pregnancy and suckling' vs 'ad libitum chow during pregnancy and suckling'environmental historyTranscription profiling by array of mice after in utero undernutrition and/or undernutrition during suckling
Adjusted p-valueLog2-fold change
1.1619 × 10-151.5
Vnn1'Adrb1, Adrb2 and Adrb3 knockout' vs 'wild type genotype' in '20 to 22 degree celsius'genotype, temperatureRNA-seq of cold-induced transcriptome changes in subcutaneous adipose tissue of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
2.5489 × 10-91.5
Vnn1'216 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
5.0478 × 10-9-1.5
Vnn1'mutant (Pdgfc-/-; Pdgfra GFP/+)' vs 'control'genotypeCerebral gene expression changes in Pdgfc and Pdgfra mutant
Adjusted p-valueLog2-fold change
1.2791 × 10-71.5
Vnn1'7 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
5.1878 × 10-61.5
Vnn1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.4077 × 10-41.5
Vnn1'10 microgram; ovalbumin' vs 'none' in 'wild type'compound, genotypeTranscription profiling by array of lungs from mice mutant for RAG after challenge with ovalbumin
Adjusted p-valueLog2-fold change
3.6432 × 10-4-1.5
Vnn1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
2.4754 × 10-31.5
Vnn1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.9896 × 10-3-1.5
Vnn1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.1863 × 10-2-1.5
Vnn1'transgenic C3(1)-SV40Tag; 16 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
1.5956 × 10-2-1.5
Vnn1'Hepatic RXR_alpha-Knockout' vs 'wild type' in 'control'genotype, treatmentGene expression data of untreated and RA-treated wild type and RXRα-deficient mice liver
Adjusted p-valueLog2-fold change
2.5355 × 10-21.5
Vnn1'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
4.6558 × 10-21.5
Vnn1'ulcer' vs 'distant normal tissue' in 'Bmp4 overexpression'genotype, sampling site, timeIntestinal ulcers from biopsy-wounded wild-type and Bmp4-overexpressing mice
Adjusted p-valueLog2-fold change
3.0864 × 10-131.4
Vnn1'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.4498 × 10-71.4
Vnn1'SARS coronavirus MA15; 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
7.7332 × 10-71.4
Vnn1'Chikungunya virus; late stage encephalitis' vs 'early stage encephalitis'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
8.004 × 10-7-1.4
Vnn1'organoid culture without Noggin (ER medium)' vs 'organoid culture (ENR medium)' in 'none'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
1.7753 × 10-5-1.4
Vnn1'induced neural stem cell' vs 'mouse embryonic fibroblast cell'cell typeGene expression profile of mouse induced neural stem cells
Adjusted p-valueLog2-fold change
2.608 × 10-5-1.4
Vnn1'Mst1/2 knockout' vs 'control'genotypeMicroarray of Mst1/2 deleted epithelial cells from E18.5 mouse lungs
Adjusted p-valueLog2-fold change
2.977 × 10-41.4
Vnn1'db/db' vs 'wild type genotype' in 'control miRNA; fasted'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.0366 × 10-31.4
Vnn1'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
1.5845 × 10-2-1.4
Vnn1'miR-34a overexpression' vs 'control'phenotypeTranscriptional profiling of lung cancer cells over-expression miR-34a.
Adjusted p-valueLog2-fold change
1.9007 × 10-2-1.4
Vnn1'missense mutation (G9492A) in Mucin 2 (Muc2)' vs 'wild type genotype'genotypeTranscription profiling of mouse intestine in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
Adjusted p-valueLog2-fold change
2.0909 × 10-2-1.4
Vnn1'TLR4 mutant' vs 'wild type genotype' in 'CCl4 and diethylnitrosamine'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
2.6961 × 10-21.4
Vnn1'low-protein/high-carbohydrate diet' vs 'western diet'dietGene expression analysis of subcutaneous adipose tissue in mice fed with a low-protein/high carbohydrate diet
Adjusted p-valueLog2-fold change
2.9642 × 10-21.4
Vnn1'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
4.029 × 10-2-1.4
Vnn1'Chromogranin A knockout' vs 'wild type genotype'genotypeTranscription profiling by array of adreanal gland samples from chromogranin A knockout mice vs wild-type controls
Adjusted p-valueLog2-fold change
4.5466 × 10-2-1.4
Vnn1'transgenic C3(1)-SV40Tag' vs 'wild type' in '8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
2.3176 × 10-17-1.3
Vnn1'interleukin-22 (Mus Musculus); 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
1.661 × 10-111.3
Vnn1'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
4.9664 × 10-91.3
Vnn1'high fat' vs 'chow' in 'A/J'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
4.3656 × 10-81.3
Vnn1'Chikungunya virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
1.223 × 10-61.3
Vnn1'diet with PPAR-alpha ligand WY14,643' vs 'control diet' in 'wild type genotype'diet, genotypeTranscription profiling of mouse small intestine from wild-type (129S1/SvImJ) and PPAR-alpha-null (129S4/SvJae) animals treated with the synthetic PPAR-alpha ligand WY14,643 (0.1% w/w) for 5 days
Adjusted p-valueLog2-fold change
3.7749 × 10-61.3
Vnn1'chronic pancreatitis' vs 'control'diseasePancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
Adjusted p-valueLog2-fold change
8.0931 × 10-51.3
Vnn1'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
5.0094 × 10-41.3
Vnn1'IEC-specific HDAC3 deletion' vs 'floxed HDAC3 (wild type)'genotypeTranscription profiling by array of intestinal epithelial cells (IECs) from mice with IEC-specific HDAC3 deletion against wild type controls
Adjusted p-valueLog2-fold change
9.0526 × 10-4-1.3
Vnn1'wild type; ethanol and ellagic acid' vs 'wild type; control'genotype, treatmentNuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages
Adjusted p-valueLog2-fold change
9.947 × 10-41.3
Vnn1'high fat diet' vs 'control'dietTranscription profiling by array of liver from mice fed a high fat diet
Adjusted p-valueLog2-fold change
1.684 × 10-31.3
Vnn1'conditional UPF2 knockout' vs 'control' in 'embryonic day 16.5'developmental stage, genotypeTranscription profiling of fetal livers of UPF2 null mice
Adjusted p-valueLog2-fold change
2.511 × 10-3-1.3
Vnn1'collagen sandwich' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.2034 × 10-3-1.3
Vnn1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '30 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
3.6094 × 10-3-1.3
Vnn1'acute graft vs. host disease' vs 'normal'compound, diseaseTranscription profiling by array of murine thymus medulla in the absence and presence of acute graft-versus-host disease
Adjusted p-valueLog2-fold change
7.636 × 10-31.3
Vnn1'control mice [Gp130f/f]; cecal ligation and puncture' vs 'control mice [Gp130f/f]; control'genotype, treatmentHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Adjusted p-valueLog2-fold change
8.7535 × 10-3-1.3
Vnn1'10 month' vs '2 month'ageRNA-seq of adipocyte progenitor cells derived from old and young mice to investigate the molecular signature of aging
Adjusted p-valueLog2-fold change
1.0122 × 10-21.3
Vnn1'14M1.4; Leishmania donovani infected' at '48 hour' vs '14M1.4; normal' at '48 hour'cell line, infect, timeTranscription profiling of 3 mouse cell lines infected with Leishmania
Adjusted p-valueLog2-fold change
1.751 × 10-2-1.3
Vnn1'inducible deletion of Mll' vs 'control'treatmentMLL regulated genes in LSK/CD48- hematopoietic stem cells
Adjusted p-valueLog2-fold change
2.101 × 10-21.3
Vnn1'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.1075 × 10-2-1.3
Vnn1'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
4.7359 × 10-2-1.3
Vnn1'liver specific SMARCB1 knockout' vs 'wild type'phenotypeTP53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors
Adjusted p-valueLog2-fold change
5.633 × 10-211.2
Vnn1'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
2.5849 × 10-101.2
Vnn1'15 degree celsius' vs '20 to 22 degree celsius' in 'wild type genotype'genotype, temperatureRNA-seq of cold-induced transcriptome changes in subcutaneous adipose tissue of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
1.0568 × 10-91.2
Vnn1'interleukin-28A; 1000 nanogram per milliliter' vs 'none'compoundTranscription profiling by high throughput sequencing of murine small intestinal epithelial cells stimulated with interleukin-28A
Adjusted p-valueLog2-fold change
8.5647 × 10-81.2
Vnn1'Trim24 knockdown' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of mouse embryonic stem cells following Trim24 and/or p53 knockdown
Adjusted p-valueLog2-fold change
4.4921 × 10-71.2
Vnn1'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.6931 × 10-51.2
Vnn1'inhibitor of kappaB kinase beta constitutively active-transgenic' vs 'wild type or single transgenic'genotypeTranscription profiling by array of embryonic mouse heart ventricles with and without cardiomycocyte-specific expression of constitutively active IKK2
Adjusted p-valueLog2-fold change
2.9901 × 10-51.2
Vnn1'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.4323 × 10-51.2
Vnn1'high fat' vs 'chow' in 'C57BL/6J'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
5.5101 × 10-51.2
Vnn1'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.5848 × 10-51.2
Vnn1'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 30 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
1.2223 × 10-41.2
Vnn1'intermittent fasting every 16 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
1.7552 × 10-41.2
Vnn1'KrasG12D extinction' vs 'sustained KrasG12D expression' in 'xenograft tumour'growth condition, phenotypeKras is required for pancreatic tumor maintenance through regulation of hexosamine biosynthesis and the non-oxidative pentose phosphate pathway
Adjusted p-valueLog2-fold change
1.8299 × 10-41.2
Vnn1'fish oil diet' vs 'control diet'dietComparative transcriptomics and metabolomic analysis of fenofibrate and fish oil treatments in mice
Adjusted p-valueLog2-fold change
2.2519 × 10-41.2
Vnn1'Apc knockout in Villin1 positive cells' vs 'wild type'phenotypeTranscription profiling by array of Apc-deficient proximal colonic epithelium upon Msx1 transcription factor depletion
Adjusted p-valueLog2-fold change
1.7133 × 10-3-1.2
Vnn1'PPARg flox/flox; Villin-Cre' vs 'wild type genotype' in 'caloric restriction'diet, genotypeMicroarray for duodenum epithelium of C57Bl6 PPARgVillinCRE and wild type mice submitted to 2 weeks 75% caloric restriction compared to ad libitum fed controls
Adjusted p-valueLog2-fold change
1.7383 × 10-31.2
Vnn1'db/db' vs 'wild type genotype' in 'control miRNA; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.8787 × 10-31.2
Vnn1'30 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.3532 × 10-31.2
Vnn1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.9522 × 10-3-1.2
Vnn1'CCl4; 1.6 gram per kilogram' at '8 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
3.6052 × 10-31.2
Vnn1'non-alcoholic fatty liver disease' vs 'normal' in 'SGLT5 knockout'disease, genotypeTranscription profiling by array of SGLT5 knockout mice under conditions of long-term fructose consumption
Adjusted p-valueLog2-fold change
4.592 × 10-31.2
Vnn1'hyperoxia' vs 'control' in 'male'sex, stimulusTranscription profiling by array of lung tissues from wild-type male and female C56BL/6J mice either maintained in room air or exposed to hyperoxia (FiO2>95%) for 48 hours
Adjusted p-valueLog2-fold change
6.3016 × 10-31.2
Vnn1'Csbm/m/Xpa-/-' vs 'wild type'genotypeTranscription profiling of liver from Csbm/m/Xpa-/- knockout mice to investigate the effect of nucleotide excision repair pathway inactivation
Adjusted p-valueLog2-fold change
3.4924 × 10-2-1.2
Vnn1'3 month; glycogen synthase knockout; liver' vs '3 month; wild type; liver'age, genotype, organism partTranscription profiling of muscles from mice with genetically modified muscle glycogen content to study the impact of glycogen content on gene expression.
Adjusted p-valueLog2-fold change
3.8837 × 10-21.2
Vnn1'liver-specific Pit1 knockout' vs 'wild type genotype' in 'regular chow diet'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
4.5407 × 10-21.2
Vnn1'hepatocyte-specific Pten knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
4.6246 × 10-21.2
Vnn1'Alb-Cre;HIF2dPA' vs 'Alb-Cre'genotypeTranscription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor
Adjusted p-valueLog2-fold change
4.6259 × 10-81.1
Vnn1'14 day' vs '0 day' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine R1 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
3.9137 × 10-71.1
Vnn1'high fat' vs 'chow' in '129S1/SvImJ'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
3.1895 × 10-61.1
Vnn1'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
3.7823 × 10-51.1
Vnn1'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
6.7009 × 10-51.1
Vnn1'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.1017 × 10-41.1
Vnn1'70 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
2.6081 × 10-41.1
Vnn1'Stat5ab+/null' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
4.1289 × 10-41.1
Vnn1'side population cells' vs 'main population cells' in 'bone marrow'cell type, organism partGene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow
Adjusted p-valueLog2-fold change
5.3283 × 10-4-1.1
Vnn1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
5.8419 × 10-41.1
Vnn1'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
6.5605 × 10-41.1
Vnn1'Nr1d1-/-' vs 'wild type genotype'genotypeTranscription profiling by array of liver tissues from wild type and Rev-erb{alpha} knockout (Nr1d1-/-) mice to study direct targets of Nr1d1 in rhythmic (circadian) transcription
Adjusted p-valueLog2-fold change
7.0768 × 10-4-1.1
Vnn1Synacthen vs sodium chloride controlcompoundTranscription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses.
Adjusted p-valueLog2-fold change
9.2606 × 10-41.1
Vnn1'Ercc1 knock-out' vs 'wild type'genotypeTranscription profiling by array of liver from Ercc1 knock-out mice
Adjusted p-valueLog2-fold change
1.6473 × 10-3-1.1
Vnn1'Tbx5;Nkx2-5 knockout' vs 'wild type'genotypeTranscription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse
Adjusted p-valueLog2-fold change
1.9097 × 10-31.1
Vnn1'PH3 homozygous knockout' vs 'wild type phenotype'phenotypePHF3 binds RNA polymerase II via the SPOC domain and regulates transcription of neuronal genes - Mouse Embryonic Stem Cell RNAseq
Adjusted p-valueLog2-fold change
4.8943 × 10-3-1.1
Vnn1'Lkb1 knock out' vs 'wild type'genotypetranscription profiling by array
Adjusted p-valueLog2-fold change
6.7958 × 10-31.1
Vnn1'non-alcoholic fatty liver disease' vs 'normal' in 'wild type'disease, genotypeTranscription profiling by array of SGLT5 knockout mice under conditions of long-term fructose consumption
Adjusted p-valueLog2-fold change
6.9207 × 10-3-1.1
Vnn1'tristetrapolin knockout' vs 'wild type' in 'none' at '0 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
7.6058 × 10-31.1
Vnn1'96 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
9.6714 × 10-31.1
Vnn1'high fat diet' vs 'control' on 'Affymetrix GeneChip Mouse Expression Array MOE430A [MOE430A]'dietTranscription profiling by array of hepatocytes from mice fed a high fat diet
Adjusted p-valueLog2-fold change
1.159 × 10-2-1.1
Vnn1'9 day' vs '0 day'timeTranscription profiling by array of mineralising murine vascular smooth muscle cell cultures over a nine day culture period to identify new regulators of vascular mineralization
Adjusted p-valueLog2-fold change
1.764 × 10-21.1
Vnn1'14M1.4; Leishmania donovani infected' at '12 hour' vs '14M1.4; normal' at '12 hour'cell line, infect, timeTranscription profiling of 3 mouse cell lines infected with Leishmania
Adjusted p-valueLog2-fold change
2.5992 × 10-2-1.1
Vnn1'unilateral ureteral obstruction' vs 'sham' in 'wild type'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
2.6202 × 10-2-1.1
Vnn1'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
3.9668 × 10-21.1
Vnn1'10 microgram; ovalbumin' vs 'none' in 'RAG null mutant'compound, genotypeTranscription profiling by array of lungs from mice mutant for RAG after challenge with ovalbumin
Adjusted p-valueLog2-fold change
4.1812 × 10-21.1
Vnn1'high fat' vs 'normal' in 'apolipoprotein E knockout'diet, genotypeGene expression from epidydimal fat pad
Adjusted p-valueLog2-fold change
4.3222 × 10-2-1.1
Vnn1'Hnf4a conditional knockout' vs 'wild type genotype'genotypeTranscription profiling of mouse conditional intestinal epithelial Hnf4Ialpha knockout to investigate the role of HNF4alpha in the adult colon
Adjusted p-valueLog2-fold change
6.0416 × 10-16-1
Vnn1'CEBPa K159R/K298R expression' vs 'wild type CEBPa expression'genotypeTranscriptome profiling of wild type, K159/298Q- and K159/298R- C/EBPα expressing mouse cells
Adjusted p-valueLog2-fold change
1.8515 × 10-71
Vnn1'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
7.9008 × 10-61
Vnn1'216 hour' vs '0 hour' on 'Affymetrix MOE430B Array'timeTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
1.0029 × 10-5-1
Vnn1'Soulatrolide; 20 milligram per kilogram per day' vs 'control; 'compoundToxicogenomics on mice liver of coumarins from Calophyllum brasiliense
Adjusted p-valueLog2-fold change
1.1002 × 10-51
Vnn1'336 hour' vs '0 hour' on 'Affymetrix MOE430B Array'timeTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
2.2416 × 10-51
Vnn1'9 day' vs '0 day' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine R1 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
6.4342 × 10-51
Vnn1'West Nile virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
1.0711 × 10-4-1
Vnn1'TGF-beta; 1.5 nanogram per milliliter' vs 'control'compoundTGF beta Dosage Experiment
Adjusted p-valueLog2-fold change
1.4202 × 10-41
Vnn1'Trim24,Trp53 double knockdown' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of mouse embryonic stem cells following Trim24 and/or p53 knockdown
Adjusted p-valueLog2-fold change
5.795 × 10-41
Vnn1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.2339 × 10-31
Vnn1'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.289 × 10-31
Vnn1'fasted' vs 're-fed' in 'wild type genotype; Gabpa miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.9316 × 10-31
Vnn1'Reverbα -/-' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
2.9891 × 10-3-1
Vnn1'Sik1 knockout; liver' vs 'wild type genotype; liver'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
3.5606 × 10-31
Vnn1'Metarhizium anisopliae crude antigen' vs 'vehicle' at '3 hour'compound, timeTranscription profiling of mouse lungs following exposure to agents of high or low allergenicity
Adjusted p-valueLog2-fold change
3.6778 × 10-3-1
Vnn1'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.1145 × 10-3-1
Vnn1'myelocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
4.1451 × 10-3-1
Vnn1'PGC-1beta mutant' vs 'wild type genotype' in 'liver'genotype, organism partTranscription profiling by array of mice lacking exons 3 to 4 of the Pgc1beta gene (PGC1beta E3,4-/E3,4- mice) against wild type controls to study the role of PGC1beta in metabolism
Adjusted p-valueLog2-fold change
4.4486 × 10-31
Vnn1'tumor necrosis factor-alpha/interleukin-17 (Mus musculus)' at '4 hour' vs 'control' at '4 hour'stimulus, timeGenome-wide comparison between IL-17 and combined TNF-alpha/ IL-17 induced genes in primary murine hepatocytes
Adjusted p-valueLog2-fold change
6.482 × 10-3-1
Vnn1'trinitrobenzene sulfonic acid' vs 'none' in 'wild type'compound, genotypeChronic TNBS Colitis in the FN14 KO Mouse
Adjusted p-valueLog2-fold change
9.0775 × 10-31
Vnn1'6 day' vs '0 day'timeTranscription profiling by array of mouse colon tissues under dextran sodium sulphate induction for 2, 4 and 6 days against uninduced controls at day 0
Adjusted p-valueLog2-fold change
1.3228 × 10-21
Vnn1'17-beta estradiol; 0.05 milligram; continuous release pellets over 60 days' vs 'none' in 'K14E7 transgenic'compound, genotype, treatmentGENE EXPRESSION PROFILE REGULATED BY THE HPV16-E7 ONCOPROTEIN AND ESTRADIOL IN CERVICAL TISSUE
Adjusted p-valueLog2-fold change
1.4964 × 10-2-1
Vnn1'caloric restriction' vs 'ad libitum' in 'PPARg flox/flox; Villin-Cre'diet, genotypeMicroarray for duodenum epithelium of C57Bl6 PPARgVillinCRE and wild type mice submitted to 2 weeks 75% caloric restriction compared to ad libitum fed controls
Adjusted p-valueLog2-fold change
1.5214 × 10-2-1
Vnn1'low serum IGF-1' vs 'wild type'phenotypeTranscription profiling of livers from female C57BL/6J and B6.C3H-6T mice to study differential gene expression in the two strains.
Adjusted p-valueLog2-fold change
1.7793 × 10-21
Vnn1'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.1927 × 10-2-1
Vnn1'homozygous conditional dicer1 knockout' vs 'wild type genotype' in 'P7 forebrain Aldh1l1-EGFP positive cell'cell type, genotypeTranscription profiling by array of wild-type or homozygous dicer1 conditional knockout forebrain P7 Aldh1l1-EGFP cells and Ald1l1-EGFP positive primary astrocytes
Adjusted p-valueLog2-fold change
2.2044 × 10-21
Vnn1'inducible knockout of Rif1 (Rif1-/-)' vs 'wild type genotype' in '4 days cre induction'genotype, growth conditionGene expression profiles of Rif1 inducible knock-out embryonic stem cells
Adjusted p-valueLog2-fold change
3.3776 × 10-21
Vnn1'CD4-CRE+ (PPAR g null)' vs 'wild type genotype' at '2 day'genotype, timeTranscription profiling by array of mouse Peroxisome proliferator-activated receptor g (PPARg) null CD4+ T cells after treatment with dextran-sodium sulfate for 2 or 7 days to induce colitis
Adjusted p-valueLog2-fold change
3.4652 × 10-2-1
Vnn1'Taf10-/-' vs 'wild type'genotypeTranscription profiling by array of liver from Taf10 knock out mice
Adjusted p-valueLog2-fold change
4.112 × 10-2-1
Vnn1'Runx3 knockout' vs 'wild type genotype' in 'CD27-low, CD11b-high natural killer cell'cell type, genotypeRunx3 function in splenic NK cells activated in vivo by IL-15.
Adjusted p-valueLog2-fold change
4.2268 × 10-2-1
Vnn1'CD2314' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
4.3584 × 10-2-1
Vnn1'CCl4; 1.6 gram per kilogram' at '24 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Synonym
pantetheinase, V-1
Ortholog
CG32750 (Drosophila melanogaster), ENSAPLG00000008759 (Anas platyrhynchos), CG32751 (Drosophila melanogaster), ENSPANG00000007996 (Papio anubis), vnn1 (Xenopus tropicalis), VNN1 (Ornithorhynchus anatinus), VNN1 (Chlorocebus sabaeus), ENSACAG00000010522 (Anolis carolinensis), ENSGALG00000048781 (Gallus gallus), vnn2 (Xenopus tropicalis), Btnd (Drosophila melanogaster), ENSACAG00000039983 (Canis familiaris), VNN1 (Sus scrofa), ENSAPLG00000008745 (Anas platyrhynchos), ENSAPLG00000027089 (Anas platyrhynchos), VNN1 (Pan troglodytes), ENSOARG00020015564 (Pongo abelii), VNN1 (Homo sapiens), ENSOARG00020019343 (Pongo abelii), VNN1 (Gorilla gorilla), VNN1 (Monodelphis domestica), VNN1 (Dasypus novemcinctus), VNN1 (Gallus gallus), Vnn1 (Rattus norvegicus), VNN1 (Bos taurus), VNN1 (Pongo abelii), vanin-like (Drosophila melanogaster), VNN1 (Macaca mulatta)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
5276305, 17232162, 168544_f_at, 4539720, 4918264, 5103223, 1447845_s_at, 5506242, 104165_at, ILMN_2455422, 4432155, 4484555, 4715206, 5542620, 10362138, 4619974, aa212803_at, 1418486_at, 5030936, 5566487
Reactome pathway ID