7.4 | | Bpifb5 | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Transcription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa |
7.1 | | Bpifb5 | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-5.2 | | Bpifb5 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
4.3 | | Bpifb5 | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
-4.3 | | Bpifb5 | 'Lin- Dapi-EpCAM- CD31+td-tomato+' vs 'Lin- Dapi-EpCAM- CD31+td-tomato-' in 'vascular endothelial cell' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
4.1 | | Bpifb5 | 'soticlestat; 30 milligram per kilogram' vs 'none' in 'astrocyte; none' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
4 | | Bpifb5 | 'hematopoietic stem cell and hematopoietic multipotent progenitor cell' vs 'common myeloid progenitor' | cell type | Transcription profiling by high throughput sequencing between multipotent hematopoietic stem progenitor cells LS+K) and myeloid committed cells (LS−K) of the mouse bone marrow |
-3.4 | | Bpifb5 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-3.2 | | Bpifb5 | 'lung carcinoma' vs 'normal' in 'lung cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
3.2 | | Bpifb5 | 'uterine-specific Tsc2-null' vs 'wild type' in 'intact' | genotype, treatment | Transcription profiling by high throughput sequencing of uterine-specific Tsc2-null mice |
-3.1 | | Bpifb5 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
3.1 | | Bpifb5 | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-2.4 | | Bpifb5 | 'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs' | growth condition | RNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs |
2.3 | | Bpifb5 | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
-2.3 | | Bpifb5 | 'Lkb1 -/- Pten-/-' vs 'wild type' | genotype | Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells |
-2.3 | | Bpifb5 | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-2.2 | | Bpifb5 | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
2.2 | | Bpifb5 | 'acute myeloid leukemia' vs 'myeloproliferative disorder' | disease | Transcription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm |
-2.1 | | Bpifb5 | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-2 | | Bpifb5 | 'SARS coronavirus MA15' vs 'none' at '7 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-2 | | Bpifb5 | 'SARS coronavirus MA15' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
1.9 | | Bpifb5 | 'Col1a1-tetO-MLL/ENL' vs 'wild type' in 'hematopoietic stem cell' | cell type, genotype | Transcription profiling by high throughput sequencing of hematopoietic stem cells from a conditional-inducible mouse model of the MLL-ENL fusion oncogene |
-1.9 | | Bpifb5 | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1.9 | | Bpifb5 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.9 | | Bpifb5 | 'Kras G12D' vs 'wild type' | genotype | Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells |
-1.9 | | Bpifb5 | "98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young" | age, phenotype | RNAseq of whole ovarian follicles from young and old mice. |
1.8 | | Bpifb5 | 'Xist-/-' vs 'wild type genotype' in 'gastrointestinal polyp' | genotype, organism part | RNA-seq of Xist deletion mouse models |
-1.8 | | Bpifb5 | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1.7 | | Bpifb5 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '4 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
-1.7 | | Bpifb5 | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '4 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1.6 | | Bpifb5 | 'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '4 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
-1.6 | | Bpifb5 | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
-1.6 | | Bpifb5 | 'SARS coronavirus MA15 dORF6' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1.6 | | Bpifb5 | 'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-1.5 | | Bpifb5 | 'PAI1 knockout; SARS MA15; 7 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.5 | | Bpifb5 | 'TIMP1 knockout; SARS MA15; 4 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.5 | | Bpifb5 | 'SARS coronavirus MA15' vs 'none' in 'Tnfrsf1a/1b -/-' at '4 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
-1.5 | | Bpifb5 | 'Stat5ab+/null' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
-1.5 | | Bpifb5 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.4 | | Bpifb5 | 'wild type genotype; SARS MA15; 7 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.4 | | Bpifb5 | 'PAI1 knockout; SARS MA15; 4 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.4 | | Bpifb5 | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.4 | | Bpifb5 | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.4 | | Bpifb5 | 'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.4 | | Bpifb5 | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.3 | | Bpifb5 | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.3 | | Bpifb5 | 'TIMP1 knockout; SARS MA15; 7 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.2 | | Bpifb5 | 'developmentally competent embryo conditioned media' vs 'control' | treatment | Developmentally Abnormal Human Embryos Trigger a Maternal ER Stress Response |
-1.2 | | Bpifb5 | 'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
-1.2 | | Bpifb5 | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1.2 | | Bpifb5 | 'Influenza A virus' vs 'mock' in 'interleukin-22' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
-1.2 | | Bpifb5 | 'SARS coronavirus MA15; 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.2 | | Bpifb5 | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.1 | | Bpifb5 | 'wild type; SARS MA15; 7 day' vs 'wild type; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
-1.1 | | Bpifb5 | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.1 | | Bpifb5 | 'dmrt1 knockout' vs 'wild type' in '129Sv' | genotype, strain | Dmrt1 (doublesex and mab-3 related transcription factor 1) conditional knockout expression analysis of E15.5 testes. |
-1.1 | | Bpifb5 | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '7 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1.1 | | Bpifb5 | 'SARS coronavirus MA15' vs 'none' in 'IFNAR1 -/-' at '5 day' | genotype, infect, time | Transcriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds |
1.1 | | Bpifb5 | 'Sall4 homozygous knockout' vs 'wild type genotype' | genotype | RNA-Seq of Sall4 mutants in mouse embryonic stem cells |
-1.1 | | Bpifb5 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Bpifb5 | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
-1 | | Bpifb5 | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
-1 | | Bpifb5 | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '4 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
-1 | | Bpifb5 | 'Mst1/2 knockout' vs 'control' | genotype | Microarray of Mst1/2 deleted epithelial cells from E18.5 mouse lungs |
-1 | | Bpifb5 | 'SARS coronavirus MA15 dORF6' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1 | | Bpifb5 | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1 | | Bpifb5 | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1 | | Bpifb5 | 'Ihhd/d' vs 'wild type' | genotype | Gene expression profiling of conditional ablation of Indian hedgehog in the mouse uterus |
1 | | Bpifb5 | 'SARS coronavirus MA15 nsp16 -/-' vs 'SARS coronavirus MA15' at '7 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
1 | | Bpifb5 | 'upf3 knockout' vs 'wild type' in 'testis' | cell type, genotype | UPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs |