ENSMUSG00000039007 (Cpq)

mus musculus

carboxypeptidase Q

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
5.3503 × 10-11-7.6
Cpq'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
4.0795 × 10-54-5.3
Cpq'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.0378 × 10-54.8
Cpq'old neuronal stem cells' vs 'young neuronal stem cells'ageA mechanism for the segregation of age in mammalian neural stem cells
Adjusted p-valueLog2-fold change
1.0575 × 10-217-4.7
Cpq'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
5.2096 × 10-604.7
Cpq'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
2.6945 × 10-804.3
Cpq'Influenza A virus' vs 'none'infectRNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals
Adjusted p-valueLog2-fold change
1.4689 × 10-8-4.3
Cpq'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
6.1398 × 10-413.9
Cpq'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
6.4321 × 10-53.8
Cpq'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.9315 × 10-43.8
Cpq'untreated; Csf2rb-/-' vs 'untreated; wild type'clinical history, genotypeMouse GM-CSF-related alveolar macrophage genome-wide expression data
Adjusted p-valueLog2-fold change
5.5294 × 10-103.6
Cpq'interleukin-3 and interleukin-33' vs 'interleukin-3'growth conditionStem cell factor programs the mast cell activation phenotype
Adjusted p-valueLog2-fold change
2.0496 × 10-9-3.5
Cpq'BCL6 knockout and inducible BACH2 overexpression' vs 'wild type and inducible BACH2 overexpression'genotypeGene expression profile of BCR-ABL1 transformed pre-B mouse cells from BCL6 knockout after inducible overexpression of Bach2
Adjusted p-valueLog2-fold change
1.2662 × 10-8-3.5
Cpq'granulocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
6.799 × 10-139-3.4
Cpq'LDB1 knock-down with full-length Ldb1 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
4.6398 × 10-82-3.4
Cpq'LDB1 knock-down' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
8.3434 × 10-183.2
Cpq'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
9.0872 × 10-113.1
Cpq'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
9.3798 × 10-113.1
Cpq'3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
8.0437 × 10-5-3
Cpq'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
2.7376 × 10-4-3
Cpq'V6.5; embryonic stem cell’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
3.0773 × 10-3-3
Cpq'one year after pulmonary macrophage transplantation; Csf2rb-/-' vs 'untreated; Csf2rb-/-'clinical history, genotypeMouse GM-CSF-related alveolar macrophage genome-wide expression data
Adjusted p-valueLog2-fold change
3.7551 × 10-82.9
Cpq'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
3.2539 × 10-102.7
Cpq'6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
4.1814 × 10-92.7
Cpq'3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
9.9266 × 10-7-2.7
Cpq'myelocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
9.48 × 10-6-2.7
Cpq'renin-expression' vs 'control'phenotypeExpression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein.
Adjusted p-valueLog2-fold change
7.8955 × 10-7-2.6
Cpq'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
4.8347 × 10-42.6
Cpq'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.7044 × 10-102.5
Cpq'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.5499 × 10-8-2.5
Cpq'induced neural stem cell' vs 'mouse embryonic fibroblast cell'cell typeGene expression profile of mouse induced neural stem cells
Adjusted p-valueLog2-fold change
4.3527 × 10-62.5
Cpq'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
4.2804 × 10-72.4
Cpq'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
6.2775 × 10-7-2.4
Cpq'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.024 × 10-42.4
Cpq'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.6768 × 10-3-2.4
Cpq'Rb^{lox/lox}; p130^{lox/lox}; p107+/-' vs 'wild type'genotypeTranscription profiling by array of livers from the mouse model of human hepatocellular carcinoma
Adjusted p-valueLog2-fold change
2.3028 × 10-22-2.3
Cpq'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
8.4936 × 10-92.3
Cpq'6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
4.3171 × 10-6-2.3
Cpq'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
2.9362 × 10-5-2.3
Cpq'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
3.173 × 10-4-2.3
Cpq'Lin- CD44+ CD25+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44+ CD25+ thymocyte progenitor cell; adult'cell type, developmental stageTranscription profiling of mouse adult and fetal T cell progenitors
Adjusted p-valueLog2-fold change
1.156 × 10-22.3
Cpq'miR-155 overexpression' vs 'wild type genotype'genotypeExpression analysis of eu-miR-155 transgenic mice B-cells.
Adjusted p-valueLog2-fold change
1.8437 × 10-15-2.2
Cpq'Tumor Necrosis Factor' vs 'none'stimulusTranscription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor
Adjusted p-valueLog2-fold change
5.4444 × 10-92.2
Cpq'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
1.3021 × 10-52.2
Cpq'5XFAD transgenic' vs 'wild type'genotypeTranscription profiling by array of microglia purified from wild type and TREM2 deficient microglia in a mouse model of Alzheimer's disease
Adjusted p-valueLog2-fold change
2.087 × 10-4-2.2
Cpq'B140H; cytosine arabinoside resistant' vs 'B140P; cytosine arabinosine sensitive'cell line, phenotypeGene expression profile of two Ara-C-resistant cell lines
Adjusted p-valueLog2-fold change
3.5725 × 10-4-2.2
Cpq'24 hour before induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
5.3191 × 10-4-2.2
Cpq'Lkb1 -/- Pten-/-' vs 'wild type'genotypeLoss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells
Adjusted p-valueLog2-fold change
1.8603 × 10-3-2.2
Cpq'neuronal stem cell; positive staining for GFP and prominin' vs 'astrocyte; positive staining for GFP'cell type, phenotypeTranscription profiling by array of adult neural stem cells (hGFAP-GFP+/prominin1+ cells) compared to parenchymal astrocytes that are not neurogenic (hGFAP-GFP+ cells from the diencephalon)
Adjusted p-valueLog2-fold change
2.6238 × 10-2-2.2
Cpq'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
6.0277 × 10-122.1
Cpq'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.4431 × 10-62.1
Cpq'osteoblast culture 9 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
2.7495 × 10-6-2.1
Cpq'side population cells' vs 'main population cells' in 'muscle'cell type, organism partGene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow
Adjusted p-valueLog2-fold change
1.5016 × 10-52.1
Cpq'Foxd3 knockout' vs 'control'phenotypeExpression data from embryonic stem cells differentiation
Adjusted p-valueLog2-fold change
4.0533 × 10-52.1
Cpq'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
6.0801 × 10-5-2.1
Cpq'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
4.2477 × 10-3-2.1
Cpq'inh-alpha/Tag transgenic' vs 'wild type' in 'none'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Adjusted p-valueLog2-fold change
2.9108 × 10-2-2.1
Cpq'30 month' vs '5 month' in 'male'age, block, sexExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Adjusted p-valueLog2-fold change
1.3876 × 10-92
Cpq'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.0406 × 10-72
Cpq'Id2_Id3_double knockout' vs 'wild type' in 'CD4+TCRb+CD8– cell; thymus'cell type, genotype, organism partTranscription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells
Adjusted p-valueLog2-fold change
2.7944 × 10-4-2
Cpq'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
5.1312 × 10-42
Cpq'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
4.6323 × 10-32
Cpq'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Adjusted p-valueLog2-fold change
4.2853 × 10-91.9
Cpq'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.068 × 10-6-1.9
Cpq'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.8536 × 10-5-1.9
Cpq'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha'genotype, stimulusRNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment
Adjusted p-valueLog2-fold change
1.8982 × 10-5-1.9
Cpq'erythroblast' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
5.098 × 10-31.9
Cpq'Tfc knockout; normal' vs 'control'disease, genotypeGene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor.
Adjusted p-valueLog2-fold change
1.9908 × 10-10-1.8
Cpq'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
4.8655 × 10-7-1.8
Cpq'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
6.8847 × 10-71.8
Cpq'7 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
7.276 × 10-71.8
Cpq'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.8521 × 10-6-1.8
Cpq'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
4.9052 × 10-51.8
Cpq'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
7.8347 × 10-5-1.8
Cpq'Rb;E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.9733 × 10-41.8
Cpq'chemical hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo.
Adjusted p-valueLog2-fold change
1.9949 × 10-41.8
Cpq'wild type; treated with angiotensin II and a combination of hydralazine and hydrochlorothiazide' vs 'wild type; vehicle'genotype, treatmentEffect of Hypertension of Dendritic Cell Gene Expression
Adjusted p-valueLog2-fold change
1.0806 × 10-3-1.8
Cpq'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; adult'cell type, developmental stageTranscription profiling of mouse adult and fetal T cell progenitors
Adjusted p-valueLog2-fold change
2.2203 × 10-31.8
Cpq'Lsd1fl/fl Mx1Cre' vs 'Lsd1fl/fl'genotypeGene expression data of Lsd1fl/fl and Lsd1fl/fl Mx1Cre Gr1dim Mac1 granulocytic progenitor cells.
Adjusted p-valueLog2-fold change
3.1099 × 10-3-1.8
Cpq'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
4.172 × 10-21.8
Cpq'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
4.7404 × 10-2-1.8
Cpq'bone marrow macrophage; co-cultured with breast cancer cell line 4T1.2' vs 'bone marrow macrophage; control'cell type, growth conditionTranscription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line
Adjusted p-valueLog2-fold change
2.816 × 10-17-1.7
Cpq'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.6599 × 10-8-1.7
Cpq'MHC II overexpression'vs 'empty retroviral vector'phenotypeEffect of MHC II expression in pro-B cells: F6 leukaemic cell line
Adjusted p-valueLog2-fold change
1.7889 × 10-8-1.7
Cpq'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
3.9166 × 10-6-1.7
Cpq'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
1.595 × 10-51.7
Cpq'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
7.7535 × 10-31.7
Cpq'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.9202 × 10-21.7
Cpq"Evi1-GFP positive" vs "Evi1-GFP negative"phenotypeWhole genome expression profiling of Evi1-GFP positive and negative murine hematopoietic stem cell sub-populations.
Adjusted p-valueLog2-fold change
4.9717 × 10-11-1.6
Cpq'organoid culture without Noggin (ER medium)' vs 'organoid culture (ENR medium)' in 'none'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
1.1168 × 10-91.6
Cpq'12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
3.3926 × 10-8-1.6
Cpq'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
6.8087 × 10-81.6
Cpq'12 day' vs '3 day'timeTranscription profiling time series of mouse embryonic chondrocyte differentiation
Adjusted p-valueLog2-fold change
1.0959 × 10-61.6
Cpq'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.4224 × 10-5-1.6
Cpq'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
2.1359 × 10-5-1.6
Cpq'10 nanogram per milliliter; TGF-beta1' vs 'none' in 'common dendritic progenitor' at '24 hour'cell type, compound, timeDynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors
Adjusted p-valueLog2-fold change
8.5446 × 10-5-1.6
Cpq'M-27; over-expressing IGF-IR' vs 'M-27; wild type'cell line, genotypeTranscription profiling of wild_type and IGF-I receptor over-expressing mouse lung carcinoma cells identifies a type I insulin like growth factor receptor regulated gene expression profile associated with an altered site-specificity of metastasis.
Adjusted p-valueLog2-fold change
8.8084 × 10-4-1.6
Cpq'Lin- CD44- CD25+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44- CD25+ thymocyte progenitor cell; adult'cell type, developmental stageTranscription profiling of mouse adult and fetal T cell progenitors
Adjusted p-valueLog2-fold change
1.2419 × 10-3-1.6
Cpq'IEC-specific HDAC3 deletion' vs 'floxed HDAC3 (wild type)'genotypeTranscription profiling by array of intestinal epithelial cells (IECs) from mice with IEC-specific HDAC3 deletion against wild type controls
Adjusted p-valueLog2-fold change
5.8835 × 10-511.5
Cpq'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
5.7767 × 10-191.5
Cpq'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
2.868 × 10-10-1.5
Cpq'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.6903 × 10-9-1.5
Cpq'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD8-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
2.8102 × 10-8-1.5
Cpq'MEF; transduced with MyoD lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
2.147 × 10-61.5
Cpq'15 day' vs '3 day'timeTranscription profiling time series of mouse embryonic chondrocyte differentiation
Adjusted p-valueLog2-fold change
1.7368 × 10-5-1.5
Cpq'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
4.8459 × 10-3-1.5
Cpq'Rb1 mutant' vs 'wild type'genotypeA retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene targeted mice
Adjusted p-valueLog2-fold change
3.1701 × 10-21.5
Cpq'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
3.69 × 10-27-1.4
Cpq'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
2.3379 × 10-25-1.4
Cpq'CpG; 6 hour' vs 'none; 0 hour' in 'none'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
3.256 × 10-71.4
Cpq'9 day' vs '3 day'timeTranscription profiling time series of mouse embryonic chondrocyte differentiation
Adjusted p-valueLog2-fold change
4.9729 × 10-7-1.4
Cpq'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
5.0778 × 10-71.4
Cpq'6 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.8893 × 10-41.4
Cpq'MFP2 knockout' vs 'wild type'genotypeDefining the microglia transcriptome in multifunctional protein-2 deficient mice
Adjusted p-valueLog2-fold change
4.3611 × 10-4-1.4
Cpq'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
4.9751 × 10-4-1.4
Cpq'STAT1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '9 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
7.1349 × 10-31.4
Cpq'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
9.4042 × 10-3-1.4
Cpq'cardiotoxin; 10 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq comparison of fibro-adipogenic progenitors (FAPs) from wild type, mdx and cardiotoxin-injured mice
Adjusted p-valueLog2-fold change
1.2037 × 10-2-1.4
Cpq'Nr4a1 Nr4a3 double knockout' vs 'wild type genotype'genotypeExpression data of mouse hematopoietic cells, Nr4a1/3 wild type and double mutant
Adjusted p-valueLog2-fold change
1.3455 × 10-21.4
Cpq'fl-CBP/Foxp3cre' vs 'wild type'genotypeTwo Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3+ T-regulatory Cell Development and Function
Adjusted p-valueLog2-fold change
1.4046 × 10-21.4
Cpq'fl-p300/Foxp3cre' vs 'wild type'genotypeTwo Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3+ T-regulatory Cell Development and Function
Adjusted p-valueLog2-fold change
2.1059 × 10-21.4
Cpq'Ubc9 overexpression' vs 'wild type genotype' in 'undifferentiated; none'genotype, growth condition, stimulusSUMOylation promotes survival and integration of neural stem cell grafts in stroke
Adjusted p-valueLog2-fold change
2.4578 × 10-21.4
Cpq'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.0095 × 10-8-1.3
Cpq'IRAK1BP1 KO' vs 'wild type' in 'none'genotype, treatmentIdentification of TNFα-induced genes that are IRAK1BP1 dependent
Adjusted p-valueLog2-fold change
5.557 × 10-81.3
Cpq'chronic pancreatitis' vs 'control'diseasePancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
Adjusted p-valueLog2-fold change
4.9672 × 10-7-1.3
Cpq'IRAK1BP1 KO' vs 'wild type' in 'TNFα'genotype, treatmentIdentification of TNFα-induced genes that are IRAK1BP1 dependent
Adjusted p-valueLog2-fold change
8.0275 × 10-71.3
Cpq'10 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
1.1207 × 10-61.3
Cpq'14 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.8669 × 10-6-1.3
Cpq'induced neural stem cell' vs 'neural stem cell'cell typeGene expression profile of mouse induced neural stem cells
Adjusted p-valueLog2-fold change
3.7636 × 10-6-1.3
Cpq'Rel -/-; Nfkb1-/-; CD4Cre Rela fx/fx' vs 'wild type genotype'genotypeRNA-seq of CD8 single positive thymocytes from WT and Rela fx/fx CD4Cre Nfkb1KO RelKO mice.
Adjusted p-valueLog2-fold change
2.4069 × 10-5-1.3
Cpq'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
6.7595 × 10-41.3
Cpq'Mist1 knockout' vs 'wild type genotype'genotypeTranscription profiling by array of pancreatic tissues from wild-type mice, Mist1 knockout mice and Mist1 knockout mice with induced (rescued) MIST1 expression
Adjusted p-valueLog2-fold change
1.2917 × 10-21.3
Cpq'K-ras mutant/Wt1-null' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
2.2693 × 10-2-1.3
Cpq'19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
2.7567 × 10-2-1.3
Cpq'normal skin; PKC alpha-/-' vs 'normal skin; wild type genotype'clinical history, genotypeAltered dermal architecture in PKCα-/- skin
Adjusted p-valueLog2-fold change
3.241 × 10-21.3
Cpq'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
4.9491 × 10-21.3
Cpq'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'BALB/cByJ'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.0959 × 10-201.2
Cpq'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
2.9223 × 10-19-1.2
Cpq'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
2.7499 × 10-151.2
Cpq'KRas siRNA' vs 'non-targeting siRNA'RNA interferenceRNA-SEQ analysis of KMC murine pancreatic ductal adenocarcinoma (PDAC) cell line upon siRNA depletion of MYC, KRas or Miz1 (aka Zbtb17)
Adjusted p-valueLog2-fold change
6.9835 × 10-14-1.2
Cpq'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
4.3421 × 10-81.2
Cpq'Zbtb10 knockdown' vs 'control' at '6 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
9.2021 × 10-71.2
Cpq"YFP positive" vs "YFP negative" in "lamina propria of small intestine"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
2.9082 × 10-61.2
Cpq"muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP negative"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
3.077 × 10-61.2
Cpq'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
4.485 × 10-5-1.2
Cpq'T-cell depleted bone marrow transplant' vs 'none' in 'normal'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
9.11 × 10-5-1.2
Cpq'conditional UPF2 knockout; before partial hepatechtomy' vs 'control; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
1.052 × 10-3-1.2
Cpq'Fhl1 knockdown by siRNA' vs 'wild type' at '3 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
1.1913 × 10-3-1.2
Cpq'acute oropharyngeal candidiasis wild type mice'; female' vs 'healthy wild type genotype mice'compound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
4.0692 × 10-3-1.2
Cpq'Lmna G609G/G609G knock in' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Lmna Gly609Gly knock in
Adjusted p-valueLog2-fold change
6.481 × 10-31.2
Cpq'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
6.8872 × 10-3-1.2
Cpq'IEC-specific HDAC3 deletion' vs 'floxed HDAC3 (wild type)'genotypeTranscription profiling by array of intestinal epithelial cells (IECs) in germ-free conditions from mice with IEC-specific HDAC3 deletion against wild type controls
Adjusted p-valueLog2-fold change
7.3123 × 10-31.2
Cpq'Sall4 -/-' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells in response to changes in Sall4
Adjusted p-valueLog2-fold change
1.2628 × 10-21.2
Cpq'12 week' vs '4 week'ageDifferential gene expression in the Lacrimal gland during development and onset of xerostomia in Sjogren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse.
Adjusted p-valueLog2-fold change
1.4888 × 10-2-1.2
Cpq'Escherichia coli O18:K1:H7; 6 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.8946 × 10-21.2
Cpq'Wt1-null' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
2.3642 × 10-2-1.2
Cpq'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
3.7861 × 10-21.2
Cpq'induction of polymicrobial sepsis' vs 'control' at '72 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
6.7848 × 10-101.1
Cpq'Col1a1-tetO-MLL/ENL' vs 'wild type' in 'hematopoietic stem cell'cell type, genotypeTranscription profiling by high throughput sequencing of hematopoietic stem cells from a conditional-inducible mouse model of the MLL-ENL fusion oncogene
Adjusted p-valueLog2-fold change
2.6609 × 10-7-1.1
Cpq'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
1.8594 × 10-61.1
Cpq'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
3.0067 × 10-61.1
Cpq'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
7.4024 × 10-6-1.1
Cpq'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.106 × 10-5-1.1
Cpq'TUT4 deficiency; TUT7 knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
1.3738 × 10-51.1
Cpq'Mkl1-RFP with a deletion of the SAP domain' vs 'full length Mkl1-RFP'genotypeTranscription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1)
Adjusted p-valueLog2-fold change
1.8009 × 10-51.1
Cpq'transgenic' vs 'wild type' in '121 day; 129Sv'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
3.3552 × 10-5-1.1
Cpq'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'co-culture'genotype, growth conditionRNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions
Adjusted p-valueLog2-fold change
4.4672 × 10-5-1.1
Cpq'chronic cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
6.3071 × 10-5-1.1
Cpq'mutant MyoD expression' at '24 hour' vs 'control' at '24 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
3.7559 × 10-4-1.1
Cpq'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
5.0808 × 10-41.1
Cpq'calorie restricted diet' vs 'normal diet' at '15 month'age, dietTranscription profiling by array of cochleae from mice fed a calorie-restricted diet
Adjusted p-valueLog2-fold change
5.7223 × 10-4-1.1
Cpq'extensive self renewing erythroblast' vs 'restrictive self renewing erythroblast'cell typeRestrictive and extensively self-renewing erythroblast
Adjusted p-valueLog2-fold change
1.7662 × 10-3-1.1
Cpq'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'non-classical monocyte'cell type, genotypeRNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice
Adjusted p-valueLog2-fold change
2.9656 × 10-3-1.1
Cpq'conditional UPF2 knockout' vs 'control' in 'embryonic day 18.5'developmental stage, genotypeTranscription profiling of fetal livers of UPF2 null mice
Adjusted p-valueLog2-fold change
3.9589 × 10-31.1
Cpq'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
5.6265 × 10-31.1
Cpq'Sall1 deficient microglia' vs 'wild type microglia'genotype, phenotypeRNA sequencing of microglia sorted form tamoxifen treated Sall1CreER/fl and control Sall1fl/fl mice
Adjusted p-valueLog2-fold change
6.8888 × 10-31.1
Cpq'Mist1 knockout with induced Mist1 expression' vs 'wild type genotype'genotypeTranscription profiling by array of pancreatic tissues from wild-type mice, Mist1 knockout mice and Mist1 knockout mice with induced (rescued) MIST1 expression
Adjusted p-valueLog2-fold change
1.0719 × 10-21.1
Cpq'Cbs knockout' vs 'wild type'genotypeGene expression profile of CD4-positive T cells from mouse Cbs knockout
Adjusted p-valueLog2-fold change
1.7373 × 10-2-1.1
Cpq'SARS coronavirus MA15 E protein mutant Δ3' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
2.039 × 10-2-1.1
Cpq'Escherichia coli O18:K1:H7; 2 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.2153 × 10-21.1
Cpq'16 week' vs '4 week'ageDifferential gene expression in the Lacrimal gland during development and onset of xerostomia in Sjogren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse.
Adjusted p-valueLog2-fold change
3.1102 × 10-21.1
Cpq'H9; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
1.2184 × 10-20-1
Cpq'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
8.2695 × 10-111
Cpq'3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
1.4222 × 10-101
Cpq'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
1.7206 × 10-7-1
Cpq'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
2.8745 × 10-61
Cpq'21 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.5445 × 10-51
Cpq'6 day' vs '3 day'timeTranscription profiling time series of mouse embryonic chondrocyte differentiation
Adjusted p-valueLog2-fold change
1.5598 × 10-5-1
Cpq'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.2051 × 10-5-1
Cpq'TUT4; TUT7 double knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
2.3705 × 10-51
Cpq'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.7729 × 10-5-1
Cpq'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
5.3236 × 10-51
Cpq'7 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
6.7481 × 10-5-1
Cpq'Ercc1 knock out' vs 'wild type'genotypeTranscription profiling by array of liver from mice mutant for Ercc1
Adjusted p-valueLog2-fold change
3.9075 × 10-41
Cpq'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
4.2058 × 10-41
Cpq'Ubc9 overexpression' vs 'wild type genotype' in 'undifferentiated; oxygen/glucose-deprivation followed by restoration of oxygen/glucose'genotype, growth condition, stimulusSUMOylation promotes survival and integration of neural stem cell grafts in stroke
Adjusted p-valueLog2-fold change
7.3542 × 10-41
Cpq'7 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
1.3238 × 10-3-1
Cpq'E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.5143 × 10-3-1
Cpq'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'control; 36 hour after partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
1.808 × 10-3-1
Cpq'lung carcinoma' vs 'normal' in 'lung cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
2.2465 × 10-31
Cpq'mir181a1/b1 Knockout' vs 'wild type'genotypeMouse CD4+/CD8+ thymocytes from miR-181a1/b1 KO vs WT
Adjusted p-valueLog2-fold change
2.7878 × 10-31
Cpq'glioblastoma multiforme' vs 'normal'diseaseAnalysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus.
Adjusted p-valueLog2-fold change
3.1782 × 10-3-1
Cpq'Fhl1 knockdown by siRNA' vs 'wild type' at '1 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
6.0655 × 10-31
Cpq'olfactomedin 4 knockout' vs 'wild type'genotypeTranscription profiling by array of Olfm4-deficient murine prostate.
Adjusted p-valueLog2-fold change
7.0965 × 10-3-1
Cpq'Mxd1 knockdown by siRNA' vs 'wild type' at '3 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
7.6369 × 10-3-1
Cpq'Tetrafluororethane; 50000 part per million; air' vs 'none; ; air'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
9.1196 × 10-31
Cpq'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
2.1213 × 10-2-1
Cpq'Trp53 Arg178Asp' vs 'wild type genotype' in 'Nutlin-3a; 10 micromolar'compound, phenotypeResidual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy