ENSMUSG00000040998 (Npnt)

mus musculus

nephronectin

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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3
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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2
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Duda et al., 2018 - organism part - …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Proteomics
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Transcriptomics
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Experimental variables
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
8.326 × 10-229.6
Npnt'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
2.5767 × 10-126.2
Npnt'MEF; transduced with MyoD lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
2.1172 × 10-7-6.1
Npnt'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
2.1572 × 10-8-5
Npnt'neural progenitor cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
7.0759 × 10-4-4.9
Npnt'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
3.0269 × 10-1294.8
Npnt'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.5983 × 10-884.4
Npnt'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.3916 × 10-244.4
Npnt'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.2784 × 10-114.2
Npnt'Sox17.Epi' vs 'Sox17.Endo'genotypeTranscription profiling by high throughput sequencing of Sox17.Epi and Endo cells from mouse embryos
Adjusted p-valueLog2-fold change
7.0268 × 10-374.1
Npnt'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.2304 × 10-174.1
Npnt'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
4.1599 × 10-423.9
Npnt'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.4338 × 10-73.9
Npnt'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
3.4872 × 10-213.7
Npnt'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
8.8572 × 10-18-3.7
Npnt'BAG6 homozygous knockout' vs 'wild type genotype'genotypeTranscription profiling of B16V mouse melanoma cells after BAG6 knockout to study impacts on extracellular vesicle mRNA cargo
Adjusted p-valueLog2-fold change
4.2649 × 10-143.7
Npnt'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
4.348 × 10-4-3.7
Npnt'neural stem cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
9.5305 × 10-43.6
Npnt'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
3.1979 × 10-253.5
Npnt'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
3.6067 × 10-273.4
Npnt'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
3.0545 × 10-223.4
Npnt'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.0879 × 10-10-3.4
Npnt'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.1547 × 10-53.4
Npnt'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha'genotype, stimulusRNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment
Adjusted p-valueLog2-fold change
4.958 × 10-113.3
Npnt'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.9307 × 10-73.3
Npnt'Lgr6-positive hair follicle/sebaceous gland cell' vs 'Lgr6-positive basal interfollicular epidermis cell'cell typeTranscription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle
Adjusted p-valueLog2-fold change
3.842 × 10-63.3
Npnt'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
8.7027 × 10-11-3.2
Npnt'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
6.8793 × 10-10-3.2
Npnt'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.9947 × 10-9-3.2
Npnt'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.2165 × 10-33.2
Npnt'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Adjusted p-valueLog2-fold change
1.4969 × 10-10-3.1
Npnt'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.4862 × 10-9-3.1
Npnt'30 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
4.0822 × 10-1333
Npnt'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
1.3652 × 10-23
Npnt'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
5.7295 × 10-83-2.9
Npnt'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
7.3183 × 10-80-2.9
Npnt'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.1281 × 10-92.9
Npnt'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
4.7643 × 10-4-2.9
Npnt'Trypanosoma brucei TREU927' vs 'uninfected'infectTranscription profiling by array of spleens from mice infected with different Trypanosoma brucei strains
Adjusted p-valueLog2-fold change
2.3986 × 10-32.9
Npnt'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
6.5958 × 10-72.8
Npnt'carotid body' vs 'adrenal medulla'organism partExpression profile of mouse carotid body and adrenal medulla [RNA-Seq]
Adjusted p-valueLog2-fold change
1.0227 × 10-3-2.8
Npnt'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
6.1417 × 10-43-2.7
Npnt'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
3.3105 × 10-25-2.7
Npnt'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.2249 × 10-92.7
Npnt'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.0855 × 10-72.7
Npnt'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
4.5997 × 10-5-2.7
Npnt'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.8129 × 10-132.6
Npnt'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.2685 × 10-11-2.6
Npnt'ATF5 knockdown' vs 'wild type' in 'DMSO'compound, genotypeMicroarray to find ATF5 dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
4.3404 × 10-10-2.6
Npnt'21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
4.2843 × 10-82.6
Npnt'7 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.7607 × 10-4-2.6
Npnt'Trypanosoma brucei STIB247' vs 'uninfected'infectTranscription profiling by array of spleens from mice infected with different Trypanosoma brucei strains
Adjusted p-valueLog2-fold change
2.0248 × 10-32.6
Npnt'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
3.2237 × 10-3-2.6
Npnt'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
7.6467 × 10-50-2.5
Npnt'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.4753 × 10-382.5
Npnt'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
1.2106 × 10-82.5
Npnt'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
2.311 × 10-82.5
Npnt'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
8.6866 × 10-42.5
Npnt'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
4.0134 × 10-132.4
Npnt'Reverbα -/-' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
2.8894 × 10-42.4
Npnt'Id2_Id3_double knockout' vs 'wild type' in 'CD4+TCRb+CD8– cell; thymus'cell type, genotype, organism partTranscription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells
Adjusted p-valueLog2-fold change
1.3605 × 10-32-2.3
Npnt'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
1.9854 × 10-112.3
Npnt'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
4.8658 × 10-92.3
Npnt'6 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
3.2414 × 10-62.3
Npnt'osteoblast culture 9 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
2.7918 × 10-52.3
Npnt'Yin Yang 1 (YY1) knockout' vs 'wild type'genotypeExpression data from mouse skeletal muscle
Adjusted p-valueLog2-fold change
1.002 × 10-42.3
Npnt'colitis' at '12 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
7.3899 × 10-42.3
Npnt'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
3.6701 × 10-3-2.3
Npnt'Hunk knockout' vs 'wild type genotype'genotypeTranscription profiling by array of mammary gland tissues from Hunk (a novel SNF1/AMPK-related protein kinase) knockout and wild type controls
Adjusted p-valueLog2-fold change
9.2683 × 10-32.3
Npnt'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
4.0014 × 10-22.3
Npnt'dorsolateral nucleus motor neuron' vs 'lumbar motor neurons'cell typeComparison of gene expression in motor pools with differential vulnerability in ALS
Adjusted p-valueLog2-fold change
4.1001 × 10-9-2.2
Npnt'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
9.8008 × 10-9-2.2
Npnt'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.5512 × 10-7-2.2
Npnt'21 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.712 × 10-62.2
Npnt'transgenic' vs 'wild type' in '121 day; 129Sv'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
7.2286 × 10-42.2
Npnt'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
2.1279 × 10-32.2
Npnt'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '30 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
9.1353 × 10-5-2.1
Npnt'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
8.3489 × 10-42.1
Npnt'tristetrapolin knockout' vs 'wild type' in 'none' at '0 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.1205 × 10-32.1
Npnt'overexpression of SRC-2' vs 'control'phenotypeA pivotal role of SRC-2 in Metastatic and Castration Resistant Prostate Cancer
Adjusted p-valueLog2-fold change
6.6827 × 10-32.1
Npnt'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
2.1644 × 10-2-2.1
Npnt'SARS coronavirus MA15 E protein mutant Δ5' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
3.8292 × 10-22.1
Npnt'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.2894 × 10-6-2
Npnt'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
3.3477 × 10-62
Npnt'5-aza-2'-deoxycytidine; 5 micromolar' vs 'none'compoundTranscription profiling by array of mouse primary dermal fibroblasts after treatment with 5-aza-2'-deoxycytidine
Adjusted p-valueLog2-fold change
9.3715 × 10-5-2
Npnt'SARS coronavirus MA15' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
5.2071 × 10-4-2
Npnt'spontaneous lung tumor' vs 'normal'disease state, diseaseTranscription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer
Adjusted p-valueLog2-fold change
6.4989 × 10-3-2
Npnt'SARS coronavirus MA15' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
6.689 × 10-3-2
Npnt'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
2.5896 × 10-8-1.9
Npnt'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
4.0162 × 10-81.9
Npnt'overexpression of alpha- and beta- Hb chains' vs 'control vector'genotypeUnexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells
Adjusted p-valueLog2-fold change
2.4499 × 10-7-1.9
Npnt'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
9.2734 × 10-7-1.9
Npnt'10 week' vs '2 week'timeTranscription profiling by array of mouse pre-frontal cortex at different time-points after birth
Adjusted p-valueLog2-fold change
1.4288 × 10-6-1.9
Npnt'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
2.3871 × 10-61.9
Npnt'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 18.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
9.431 × 10-61.9
Npnt'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
1.7709 × 10-4-1.9
Npnt'SARS coronavirus MA15 dORF6' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
1.592 × 10-3-1.9
Npnt'high fat diet' vs 'chow diet' in 'SHP knockout'genotype, growth conditionTranscription profiling of small heterodimer partner deficiency (SHP) knockout mice heart
Adjusted p-valueLog2-fold change
1.7444 × 10-3-1.9
Npnt'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.7806 × 10-3-1.9
Npnt'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
2.7305 × 10-3-1.9
Npnt'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
3.4408 × 10-31.9
Npnt'K-ras mutant' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
4.9897 × 10-31.9
Npnt'Nr1d1 homozygous knockout' vs 'wild type genotype' in 'methyl beta-clodextrin; 1 milligram per kilogram; ZT6'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
9.814 × 10-31.9
Npnt'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'inguinal fat pad'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
2.7828 × 10-21.9
Npnt'Lgr6-positive hair follicle/sebaceous gland cell' vs 'basal keratinocyte'cell typeTranscription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle
Adjusted p-valueLog2-fold change
3.0749 × 10-2-1.9
Npnt'SARS coronavirus MA15 lacking full-length E protein' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
4.177 × 10-2-1.9
Npnt'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
7.741 × 10-36-1.8
Npnt'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
8.9437 × 10-28-1.8
Npnt'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.8064 × 10-23-1.8
Npnt'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
8.006 × 10-16-1.8
Npnt'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.3029 × 10-6-1.8
Npnt'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
3.6485 × 10-5-1.8
Npnt'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
1.336 × 10-41.8
Npnt'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day'compound, genotype, timeTranscription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin
Adjusted p-valueLog2-fold change
2.3048 × 10-31.8
Npnt'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.0776 × 10-21.8
Npnt'left ventricle' vs 'right ventricle' in 'embryonic day 18.5'developmental stage, organism partTranscriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome
Adjusted p-valueLog2-fold change
3.8434 × 10-2-1.8
Npnt'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; lipopolysaccharide; 10 nanogram per milliliter'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.5197 × 10-22-1.7
Npnt'interferon gamma; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
4.0208 × 10-151.7
Npnt'intestinal smooth muscle culture supernatant' vs 'none' in 'organoid culture without Noggin (ER medium)'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
2.6502 × 10-131.7
Npnt'hepatocyte-derived proliferative ducts (hepPDs)' vs 'biliary-derived proliferative ducts (bilDP)'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
6.2004 × 10-11-1.7
Npnt'doxycycline; 200 nanogram per milliliter; neoplasm; 12 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
2.6731 × 10-5-1.7
Npnt'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
5.2879 × 10-51.7
Npnt'transgenic' vs 'wild type' in '160 day; C57BL/6'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
4.852 × 10-4-1.7
Npnt'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
2.7049 × 10-21.7
Npnt'11beta-HSD knockout' vs 'wild type' in 'subcutaneous adipose tissue'genotype, organism partTranscription profiling of adipose tissue from mesenteric and subcutaneous depots from 11beta-HSD1 knockout and wild type mice
Adjusted p-valueLog2-fold change
2.8183 × 10-38-1.6
Npnt'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
3.3946 × 10-91.6
Npnt'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
9.1465 × 10-71.6
Npnt'Meis1; Meis2 conditional knockout' vs 'wild type phenotype'phenotypeMeis homeobox genes control cell competence within the eye-specified neuroepithelium (RNA-seq)
Adjusted p-valueLog2-fold change
1.4977 × 10-5-1.6
Npnt'bevacizumab' vs 'control'compoundGene expression profile of U87-EV human glioblastoma xenograft tumours treated with bevacizumab or dibenzazepine
Adjusted p-valueLog2-fold change
5.5971 × 10-5-1.6
Npnt'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
7.5546 × 10-5-1.6
Npnt'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
1.3163 × 10-31.6
Npnt'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.6753 × 10-2-1.6
Npnt'total RNA; HRasV12 and c-Myc overexpression and Eif4e heterozygous knockout' vs 'total RNA; wild type'fraction, genotypeRedefining the role of eIF4E dose in development, cancer, and protein synthesis
Adjusted p-valueLog2-fold change
1.9217 × 10-21.6
Npnt'Wt1-null' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
2.5732 × 10-2-1.6
Npnt'Pcl2 knockdown' vs 'control'genotypeGene expression profile in mouse embryonic stem cells in which endogenous Pcl2 expression was stably knocked down using short hairpin RNA
Adjusted p-valueLog2-fold change
1.3062 × 10-29-1.5
Npnt'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
7.0132 × 10-18-1.5
Npnt'interleukin-22 (Mus Musculus); 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
5.3985 × 10-14-1.5
Npnt'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
4.942 × 10-131.5
Npnt'0.45 micromolar; 5-fluourouracil' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid
Adjusted p-valueLog2-fold change
4.4123 × 10-81.5
Npnt'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
8.3711 × 10-7-1.5
Npnt'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
9.4776 × 10-7-1.5
Npnt'wild type; SARS MA15; 2 day' vs 'wild type; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
2.2838 × 10-6-1.5
Npnt'4 week' vs '2 week'timeTranscription profiling by array of mouse pre-frontal cortex at different time-points after birth
Adjusted p-valueLog2-fold change
6.4891 × 10-6-1.5
Npnt'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
9.1847 × 10-6-1.5
Npnt'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.9701 × 10-5-1.5
Npnt'Influenza A virus' vs 'none'infectRNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals
Adjusted p-valueLog2-fold change
6.1749 × 10-5-1.5
Npnt'14 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
4.5653 × 10-4-1.5
Npnt'Mycobacterium tuberculosis; DBA/2J congenic; 30 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
1.3702 × 10-31.5
Npnt'Stella knockout' vs 'wild type genotype' in 'oocyte'developmental stage, genotypeTranscription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development
Adjusted p-valueLog2-fold change
6.8906 × 10-31.5
Npnt'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
7.5073 × 10-3-1.5
Npnt'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
9.1435 × 10-3-1.5
Npnt'Hnf1a knock out' vs 'wild type'genotypeTranscription profiling of pancreatic islets from Hnf1a-deficient and wild type mice
Adjusted p-valueLog2-fold change
1.1469 × 10-21.5
Npnt'conditional UPF2 knockout; before partial hepatechtomy' vs 'control; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
1.1601 × 10-21.5
Npnt'Nutlin-3a; 150 milligram per kilogram per day' vs 'none' in 'p53 heterozygous mutant'compound, phenotypeRNA-seq of mouse colon to investigate how suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity
Adjusted p-valueLog2-fold change
1.2599 × 10-2-1.5
Npnt'ductus arteriosis' vs 'aorta'organism partGene Profiling in Mouse Fetal Ductus Arteriosus
Adjusted p-valueLog2-fold change
1.4374 × 10-21.5
Npnt'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
2.0026 × 10-21.5
Npnt'oculomotor nucleus motor neurons' vs 'lumbar motor neurons'cell typeComparison of gene expression in motor pools with differential vulnerability in ALS
Adjusted p-valueLog2-fold change
2.7228 × 10-21.5
Npnt'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
3.2646 × 10-21.5
Npnt'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 15.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
3.7784 × 10-21.5
Npnt'K-ras mutant/Wt1-null' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
7.921 × 10-181.4
Npnt'Sip1 knock out' vs 'wild type'genotypeSip1 in cortical interneuron migration
Adjusted p-valueLog2-fold change
7.0709 × 10-12-1.4
Npnt'KrasG12D' vs 'wild type'genotypeAn oncogenic Kras expression signature identified by cross-species
Adjusted p-valueLog2-fold change
4.686 × 10-5-1.4
Npnt'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
5.9454 × 10-51.4
Npnt'Med1 knockout' vs 'wild type' in 'ventral prostate'genotype, organism partChanges in gene expression caused by loss of Med1 in the mouse prostate
Adjusted p-valueLog2-fold change
3.2998 × 10-41.4
Npnt'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'separate'genotype, growth conditionRNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions
Adjusted p-valueLog2-fold change
3.9392 × 10-4-1.4
Npnt'5,9-endoperoxy-cholest-7-en-3β,6α-diol' vs 'vehicle (cyclodextrin)'compound, timeArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
Adjusted p-valueLog2-fold change
5.5616 × 10-4-1.4
Npnt'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, and PLAT knock-out mice
Adjusted p-valueLog2-fold change
8.8347 × 10-41.4
Npnt'wild type; mature luminal' vs 'wild type; MaSC/basal'cell type, genotypeExpression data from sorted control and Pygo2-null mouse mammary stem/basal cells
Adjusted p-valueLog2-fold change
1.9402 × 10-3-1.4
Npnt'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.9827 × 10-31.4
Npnt'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
2.8258 × 10-31.4
Npnt'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
6.3364 × 10-3-1.4
Npnt'Hnf4a-pKO;Hnf1aHET double mutant' vs 'wild type genotype'genotypeTranscription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice
Adjusted p-valueLog2-fold change
8.9392 × 10-31.4
Npnt'intermittent fasting every 16 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
1.249 × 10-21.4
Npnt'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.7323 × 10-21.4
Npnt'shRNA mediated depletion of TUNA' vs 'control' at '4 day'time, treatmentTranscriptome Analysis of LincRNA TUNA Knockdown in Mouse Embryonic Stem Cells
Adjusted p-valueLog2-fold change
2.6571 × 10-2-1.4
Npnt'SARS coronavirus MA15' vs 'none' at '4 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
3.4465 × 10-21.4
Npnt'cardiotoxin; 40 microliter' vs 'none' in 'MLC-CnAb1 overexpression' at '12 day'compound, genotype, timeTranscription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin
Adjusted p-valueLog2-fold change
3.806 × 10-21.4
Npnt'Fhl1 knockdown by siRNA' vs 'wild type' at '3 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
4.235 × 10-101.3
Npnt'Adrb1, Adrb2 and Adrb3 knockout' vs 'wild type genotype' in '20 to 22 degree celsius'genotype, temperatureRNA-seq of cold-induced transcriptome changes in skeletal muscle of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
1.2164 × 10-8-1.3
Npnt'Irgm1 knockout' vs 'wild type genotype' in 'bone marrow'genotype, organism partRNA-Seq of bone marrow derived macophages (BMDMs) and brain tissue isolated from wild type and Irgm1 knockout mice
Adjusted p-valueLog2-fold change
2.772 × 10-7-1.3
Npnt'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.1185 × 10-7-1.3
Npnt'West Nile virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
2.2692 × 10-6-1.3
Npnt'cut nerve; 7 day' vs 'none'injury, protocol, timeChanges in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury
Adjusted p-valueLog2-fold change
3.4008 × 10-6-1.3
Npnt'PPARgamma2 overexpression' vs 'empty vector' at '10 day'genotype, timeTranscription profiling by array of mouse NIH3T3 cells over-expressing PPARg pr EBF1 over time
Adjusted p-valueLog2-fold change
5.3865 × 10-6-1.3
Npnt'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
7.6493 × 10-6-1.3
Npnt'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
1.2958 × 10-5-1.3
Npnt'3 week' vs '2 week'timeTranscription profiling by array of mouse pre-frontal cortex at different time-points after birth
Adjusted p-valueLog2-fold change
9.5488 × 10-5-1.3
Npnt'5 week' vs '2 week'timeTranscription profiling by array of mouse pre-frontal cortex at different time-points after birth
Adjusted p-valueLog2-fold change
1.4342 × 10-4-1.3
Npnt'acute oropharyngeal candidiasis' vs 'healthy' in wild type micecompound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
2.9948 × 10-4-1.3
Npnt'Lkb1 -/- Pten-/-' vs 'wild type'genotypeLoss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells
Adjusted p-valueLog2-fold change
3.3512 × 10-4-1.3
Npnt'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 30 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
7.6381 × 10-41.3
Npnt'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
3.2649 × 10-3-1.3
Npnt'TGFβ, 5 nanogram per milliliter' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
5.7273 × 10-3-1.3
Npnt'V6.5; embryonic stem cell’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
8.6528 × 10-3-1.3
Npnt'PAI1 knockout; SARS MA15; 4 day' vs 'PAI1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
1.0265 × 10-21.3
Npnt'CD2314' vs 'none' at '6 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
2.1078 × 10-2-1.3
Npnt'30 month' vs '5 month' in 'male'age, block, sexExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Adjusted p-valueLog2-fold change
2.3321 × 10-2-1.3
Npnt'doxycycline-induced inactivation of ErbB3' vs 'ErbB3 expression'phenotypeTranscription profiling by array of mouse mammary epithelial organoids after doxycyline-induced repression of ErbB3 expression
Adjusted p-valueLog2-fold change
2.559 × 10-21.3
Npnt'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
2.6388 × 10-2-1.3
Npnt'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '12 month'age, genotypeErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression]
Adjusted p-valueLog2-fold change
4.1833 × 10-2-1.3
Npnt'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.3568 × 10-131.2
Npnt'Drosha -/-' vs 'wild type genotype'genotypeRNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs
Adjusted p-valueLog2-fold change
2.7328 × 10-10-1.2
Npnt'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.5549 × 10-9-1.2
Npnt'R6/2' vs 'wild type genotype'genotypeGene expression data from cortex of 15 week old wild type, R6/2, HDAC4het and R6/2::HDAC4het mice
Adjusted p-valueLog2-fold change
1.6866 × 10-81.2
Npnt'Mettl6 knockout clone D1' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
1.127 × 10-71.2
Npnt'Adrb1, Adrb2 and Adrb3 knockout' vs 'wild type genotype' in '15 degree celsius'genotype, temperatureRNA-seq of cold-induced transcriptome changes in skeletal muscle of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
3.296 × 10-71.2
Npnt'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
3.8641 × 10-7-1.2
Npnt'wild type genotype; SARS MA15; 7 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
1.4127 × 10-6-1.2
Npnt'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.8959 × 10-6-1.2
Npnt'MG132; 1 micromolar' vs 'DMSO' in 'CHOP-/-'compound, genotypeMicroarray to find CHOP dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
3.026 × 10-51.2
Npnt'Tgfbeta 1 ligand 0.04 nanogram per milliliter' vs 'none'compoundExpression data from intestinal organoids altered for Tgfbeta signaling
Adjusted p-valueLog2-fold change
4.2655 × 10-5-1.2
Npnt'anti mTNF-alpha; 250 microgram' vs 'saline' in 'wild type; Mycobacterium tuberculosis H37Rv'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
2.066 × 10-41.2
Npnt'Crx knockout' vs 'control' at '6 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
5.4588 × 10-4-1.2
Npnt'Metarhizium anisopliae crude antigen' vs 'vehicle' at '12 hour'compound, timeTranscription profiling of mouse lungs following exposure to agents of high or low allergenicity
Adjusted p-valueLog2-fold change
8.6788 × 10-4-1.2
Npnt'postnatal day 21; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
1.8457 × 10-3-1.2
Npnt'Klf5 knockout' vs 'wild type Klf5'genotypeExpression data from conditional Klf5 knockout Pten-null mouse prostates
Adjusted p-valueLog2-fold change
4.645 × 10-3-1.2
Npnt'GW501516' at '48 hour' vs 'none'compound, timePPARd target genes in MEFs
Adjusted p-valueLog2-fold change
5.7566 × 10-31.2
Npnt'aire knock out' vs 'wild type'genotypeTranscription profiling by array of mice mutant for aire
Adjusted p-valueLog2-fold change
1.0553 × 10-2-1.2
Npnt'TIMP1 knockout; SARS MA15; 4 day' vs 'TIMP1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
1.0815 × 10-21.2
Npnt'transgenic' vs 'wild type' in '133 day; C57BL/6'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
1.4093 × 10-21.2
Npnt'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
1.7954 × 10-2-1.2
Npnt'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '7 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.8828 × 10-2-1.2
Npnt'doxycycline-induced expression of NGN3' vs 'control' at '24 hour'time, treatmentTranscription profiling by array of mouse embryonic stem cells expressing the transcription factor NGN3 for 12 hours, 24 hours and 48 hours
Adjusted p-valueLog2-fold change
1.9716 × 10-2-1.2
Npnt'miR-155 knockout' vs 'wild type' in 'natural killer cell'cell type, genotypeContext- and cell-type specific function of miR155-Socs1 interaction in immune regulation
Adjusted p-valueLog2-fold change
2.6066 × 10-2-1.2
Npnt'19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
3.7834 × 10-21.2
Npnt'InsR, Igf1R double knockout' vs 'wild type' in 'postnatal day 5'developmental stage, genotypeTranscriptional profiling by array of mouse wild-type and Insulin receptor (InsR)/Igf1 receptor (Igf1R) double knockout mutant Sertoli cells from testis at embryonic day E17.5 and Postnatal day 5
Adjusted p-valueLog2-fold change
4.9187 × 10-21.2
Npnt'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
4.6171 × 10-52-1.1
Npnt'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'endothelial cell; expressing AKT1'cell type, growth condition, phenotypeTranscription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture
Adjusted p-valueLog2-fold change
7.9183 × 10-111.1
Npnt'Cnot3 knockout' vs 'wild type'phenotypeRNA-seq of mouse islets from Ins1-cre driven Cnot3 KO and control islets
Adjusted p-valueLog2-fold change
4.9943 × 10-9-1.1
Npnt'N-acetylcysteine; 7 day differentiated; 1 millimolar' vs 'none; 7 day differentiated'compound, developmental stageRNA-seq of C17.2 neuronal progenitor cells exposed to cerium oxide nanoparticles during cell differentiation
Adjusted p-valueLog2-fold change
2.5339 × 10-8-1.1
Npnt'Mycobacterium tuberculosis H37Rv' vs 'none'infectThe global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice
Adjusted p-valueLog2-fold change
6.434 × 10-8-1.1
Npnt'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
5.5888 × 10-7-1.1
Npnt'HDAC4het' vs 'wild type genotype'genotypeGene expression data from cortex of 15 week old wild type, R6/2, HDAC4het and R6/2::HDAC4het mice
Adjusted p-valueLog2-fold change
1.9048 × 10-6-1.1
Npnt'LKB1 knockout; floxed LKB1 with RIP-Cre' vs 'floxed LKB1 without RIP-Cre; wild type'genotype, phenotypeTranscription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice
Adjusted p-valueLog2-fold change
2.3343 × 10-61.1
Npnt'Sall4 ZFC4mut' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
4.9878 × 10-6-1.1
Npnt'organoid culture without Noggin (ER medium)' vs 'organoid culture (ENR medium)' in 'none'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
5.0361 × 10-6-1.1
Npnt'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.216 × 10-6-1.1
Npnt'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.8268 × 10-5-1.1
Npnt'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 70 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
5.417 × 10-5-1.1
Npnt'R6/2 transgenic' vs 'wild type' in '12 week; brain cortex'age, genotype, organism partTranscription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks.
Adjusted p-valueLog2-fold change
8.1876 × 10-51.1
Npnt'Lmna G609G/G609G knock in' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Lmna Gly609Gly knock in
Adjusted p-valueLog2-fold change
1.7179 × 10-4-1.1
Npnt'3 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
2.7086 × 10-4-1.1
Npnt'Influenza A virus' vs 'mock' in 'interleukin-22'infect, stimulusTranscription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza
Adjusted p-valueLog2-fold change
4.3063 × 10-4-1.1
Npnt'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.0519 × 10-31.1
Npnt'CD36 knockout' vs 'wild type genotype' in 'none'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
1.0635 × 10-31.1
Npnt'mdx' vs 'wild type' in 'postnatal day 23'developmental stage, genotypeTranscription profiling of mouse hindlimb muscle, comparison of wild type and mdx mice, 7 to 112 Day
Adjusted p-valueLog2-fold change
1.3361 × 10-3-1.1
Npnt'70 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
2.7442 × 10-3-1.1
Npnt'E2f1, E2f2, E2f3 triple knockout' vs 'control' at 'neonate'developmental stage, genotypeExpression data from lenses triply deficient for E2F1, E2F2, and E2F3 transcription factors
Adjusted p-valueLog2-fold change
2.8336 × 10-3-1.1
Npnt'acute oropharyngeal candidiasis wild type mice'; female' vs 'healthy wild type genotype mice'compound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
3.2213 × 10-3-1.1
Npnt'early B-cell factor 1 overexpression' vs 'empty vector' at '4 day'genotype, timeTranscription profiling by array of mouse NIH3T3 cells over-expressing PPARg pr EBF1 over time
Adjusted p-valueLog2-fold change
3.399 × 10-31.1
Npnt'neoplasm' vs 'normal tissue adjacent to neoplasm'sampling siteTranscription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa
Adjusted p-valueLog2-fold change
3.5269 × 10-3-1.1
Npnt'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
9.1587 × 10-3-1.1
Npnt'pkd1 knockout' vs 'wild type' in 'presence of fluid flow'genotype, stimulusTranscription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow
Adjusted p-valueLog2-fold change
1.1964 × 10-2-1.1
Npnt'H-Ras expression; c-Myc activation' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
1.6672 × 10-2-1.1
Npnt'100 nanomolar endothelin-1' vs 'none'compoundTranscription profiling by array of mouse primary dermal fibroblasts after treatment with endothelin-1
Adjusted p-valueLog2-fold change
1.6672 × 10-2-1.1
Npnt'endothelin-1' vs 'control'compoundTranscription profiling of mouse dermal fibroblasts following exposure to endothelin-1
Adjusted p-valueLog2-fold change
2.1668 × 10-2-1.1
Npnt'Nix knock out' vs 'wild type'genotypeTranscription profiling by array of spleens from mice with Nix knocked out.
Adjusted p-valueLog2-fold change
2.6891 × 10-2-1.1
Npnt'fear conditioning' vs 'none'stimulusGene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage
Adjusted p-valueLog2-fold change
4.3041 × 10-21.1
Npnt'untreated; Csf2rb-/-' vs 'untreated; wild type'clinical history, genotypeMouse GM-CSF-related alveolar macrophage genome-wide expression data
Adjusted p-valueLog2-fold change
4.9746 × 10-21.1
Npnt'beta(3)-adrenergic agonist Cl316,243' vs 'none' at '10 week'age, stimulusRNA-seq of age-associated transcriptome changes in brown adipose tissue
Adjusted p-valueLog2-fold change
2.1878 × 10-11-1
Npnt'AMPK double knockout; floxed AMPK alpha 1 and 2 with Ins1-Cre' vs 'floxed AMPK without Ins1-Cre; wild type'genotype, phenotypeTranscription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice
Adjusted p-valueLog2-fold change
2.3045 × 10-11-1
Npnt'K14-Cre-ERT2; none; UVB irradiation; 7 day' vs 'K14-Cre-ERT2; none; none'genotype, irradiate, timeAblation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin
Adjusted p-valueLog2-fold change
5.9542 × 10-111
Npnt'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
1.2325 × 10-10-1
Npnt'epithelium-specific mutant beta-catenin expression' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
2.2639 × 10-61
Npnt'anti-CD3/anti-CD28' vs 'none' in 'empty vector'genotype, stimulusTranscription profiling by array of FOXP3 overexpression in resting and activated mouse CD4+ T cells
Adjusted p-valueLog2-fold change
1.5927 × 10-51
Npnt'ReverbαFlox2-6AdipoCre+' vs 'ReverbαFlox2-6AdipoCre-' in 'normal chow; 28 week'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
2.6507 × 10-5-1
Npnt'10 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
3.6002 × 10-5-1
Npnt'MG132; 1 micromolar' vs 'DMSO' in 'wild type'compound, genotypeMicroarray to find CHOP dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
3.6079 × 10-5-1
Npnt'24 hour' vs '0 hour' in 'WT1-KTS'genotype, timeEWS-WT1 Oncogene Activates a Neuronal Reprogramming Factor ASCL1 and Mediates Partial Neural Differentiation
Adjusted p-valueLog2-fold change
2.9137 × 10-4-1
Npnt'rosiglitazone; 100 nanomolar' vs 'none' in 'wild type genotype'compound, genotypeTranscriptional response to Rosiglitazone in adipocyte progenitors isolated from WT and Cited4-KO scWAT
Adjusted p-valueLog2-fold change
4.7777 × 10-41
Npnt'injected with sperm-derived RNA fragments from mice subjected to early life stress (MSUS)' vs 'injected with sperm-derived RNA fragments from control non-stressed mice'stimulusZygotic expression after parental early life stress
Adjusted p-valueLog2-fold change
9.5595 × 10-4-1
Npnt'TIMP1 knockout; SARS MA15; 7 day' vs 'TIMP1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
1.6214 × 10-3-1
Npnt'rosiglitazone; 100 nanomolar' vs 'none' in 'Cited4-/-'compound, genotypeTranscriptional response to Rosiglitazone in adipocyte progenitors isolated from WT and Cited4-KO scWAT
Adjusted p-valueLog2-fold change
2.1446 × 10-3-1
Npnt'7 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.1544 × 10-3-1
Npnt'shRNA p68/p72 knockdown; differentiated' vs 'control; differentiated' on 'Affymetrix Array MOE430A'RNA interference, developmental stageTranscription profiling of p68/72 deficient C2C12 cells to investigate the function of p68/p72 in muscle gene expression and skeletal C2C12 cell differentiation.
Adjusted p-valueLog2-fold change
4.6144 × 10-31
Npnt'20 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance
Adjusted p-valueLog2-fold change
4.6163 × 10-31
Npnt'adipose tissue specific Trim28 knockout' vs 'wild type genotype' in 'male'genotype, sexRNA-seq of gonadal adipose tissue from male and female Trim28-WT and Trim28 adipose specific KO mice
Adjusted p-valueLog2-fold change
4.8275 × 10-3-1
Npnt'3 day' vs '1 day' in 'influenza A infected DBA/2J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
6.6108 × 10-3-1
Npnt'PGC-1 beta knock in' vs 'wild type'genotypeTranscription profiling by array of skeletal muscle from PGC-1 beta transgenic mice
Adjusted p-valueLog2-fold change
7.1819 × 10-31
Npnt'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'control; 36 hour after partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
8.2921 × 10-31
Npnt'transgenic' vs 'wild type' in '152 day; C57BL/6'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
1.0225 × 10-21
Npnt'H9; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
1.3335 × 10-21
Npnt'SARS coronavirus MA15 nsp16 -/-' vs 'SARS coronavirus MA15' at '7 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
1.7069 × 10-2-1
Npnt'high fat diet' vs 'chow diet' in 'wild type'genotype, growth conditionTranscription profiling of small heterodimer partner deficiency (SHP) knockout mice heart
Adjusted p-valueLog2-fold change
1.9033 × 10-2-1
Npnt'miR-34a overexpression' vs 'control'phenotypeTranscriptional profiling of lung cancer cells over-expression miR-34a.
Adjusted p-valueLog2-fold change
1.9765 × 10-21
Npnt'high fat' vs 'chow' in 'NZO/HILtJ'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
2.3634 × 10-2-1
Npnt'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
3.3017 × 10-21
Npnt'CD4-CRE+ (PPAR g null)' vs 'wild type genotype' at '2 day'genotype, timeTranscription profiling by array of mouse Peroxisome proliferator-activated receptor g (PPARg) null CD4+ T cells after treatment with dextran-sodium sulfate for 2 or 7 days to induce colitis
Synonym
POEM, 1110009H02Rik
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4735051, 4616920, 5525204, 10502240, 4623480, ILMN_1252248, 4605033, aa223007_s_at, A_52_P382785, A_52_P598895, 1426561_a_at, 5103539, A_51_P289889, 4524747, 5529664, 17410435, 1452106_at, 5470759, 4388326, 5382376, 5031842, 5062408, 116126_at, 4517167, 4839644, 1421429_a_at, 1452107_s_at, ILMN_3154279, 103721_at, 1426560_a_at, A_55_P1993549, 5047176, 5064650, 5003174