9.6 | | Npnt | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
6.2 | | Npnt | 'MEF; transduced with MyoD lentivirus' vs 'MEF; control' | cell line, treatment | Genetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling] |
-6.1 | | Npnt | '70 week' vs '6 week' in 'none; none; | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
-5 | | Npnt | 'neural progenitor cell' vs 'niche cell' | cell type | Transcription profiling by high throughput sequencing of three populations of primary dentate gyrus cells |
-4.9 | | Npnt | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
4.8 | | Npnt | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
4.4 | | Npnt | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
4.4 | | Npnt | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
4.2 | | Npnt | 'Sox17.Epi' vs 'Sox17.Endo' | genotype | Transcription profiling by high throughput sequencing of Sox17.Epi and Endo cells from mouse embryos |
4.1 | | Npnt | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
4.1 | | Npnt | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
3.9 | | Npnt | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
3.9 | | Npnt | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
3.7 | | Npnt | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-3.7 | | Npnt | 'BAG6 homozygous knockout' vs 'wild type genotype' | genotype | Transcription profiling of B16V mouse melanoma cells after BAG6 knockout to study impacts on extracellular vesicle mRNA cargo |
3.7 | | Npnt | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-3.7 | | Npnt | 'neural stem cell' vs 'niche cell' | cell type | Transcription profiling by high throughput sequencing of three populations of primary dentate gyrus cells |
3.6 | | Npnt | 'synovial sarcoma' vs 'normal' | disease | Transcription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice |
3.5 | | Npnt | 'liver-specific Cnot3 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
3.4 | | Npnt | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
3.4 | | Npnt | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-3.4 | | Npnt | '90 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
3.4 | | Npnt | 'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha' | genotype, stimulus | RNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment |
3.3 | | Npnt | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
3.3 | | Npnt | 'Lgr6-positive hair follicle/sebaceous gland cell' vs 'Lgr6-positive basal interfollicular epidermis cell' | cell type | Transcription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle |
3.3 | | Npnt | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-3.2 | | Npnt | '365 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-3.2 | | Npnt | '730 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-3.2 | | Npnt | '60 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
3.2 | | Npnt | 'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
-3.1 | | Npnt | '180 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-3.1 | | Npnt | '30 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
3 | | Npnt | 'induced neuronal cell' vs 'pluripotent embryonic stem cell' | phenotype | Transcription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells |
3 | | Npnt | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.9 | | Npnt | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-2.9 | | Npnt | 'Irx3 knockout' vs 'control' at '7 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
2.9 | | Npnt | '10 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-2.9 | | Npnt | 'Trypanosoma brucei TREU927' vs 'uninfected' | infect | Transcription profiling by array of spleens from mice infected with different Trypanosoma brucei strains |
2.9 | | Npnt | 'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
2.8 | | Npnt | 'carotid body' vs 'adrenal medulla' | organism part | Expression profile of mouse carotid body and adrenal medulla [RNA-Seq] |
-2.8 | | Npnt | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-2.7 | | Npnt | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
-2.7 | | Npnt | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.7 | | Npnt | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
2.7 | | Npnt | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-2.7 | | Npnt | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
2.6 | | Npnt | 'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-2.6 | | Npnt | 'ATF5 knockdown' vs 'wild type' in 'DMSO' | compound, genotype | Microarray to find ATF5 dependent genes in response to proteasome inhibition |
-2.6 | | Npnt | '21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
2.6 | | Npnt | '7 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-2.6 | | Npnt | 'Trypanosoma brucei STIB247' vs 'uninfected' | infect | Transcription profiling by array of spleens from mice infected with different Trypanosoma brucei strains |
2.6 | | Npnt | 'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
-2.6 | | Npnt | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
-2.5 | | Npnt | 'Irx3 knockout' vs 'control' at '1 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
2.5 | | Npnt | 'Sall4 homozygous knockout' vs 'wild type genotype' | genotype | RNA-Seq of Sall4 mutants in mouse embryonic stem cells |
2.5 | | Npnt | 'liver-specific Cnot1 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
2.5 | | Npnt | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
2.5 | | Npnt | 'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
2.4 | | Npnt | 'Reverbα -/-' vs 'wild type genotype' | genotype | Antibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq |
2.4 | | Npnt | 'Id2_Id3_double knockout' vs 'wild type' in 'CD4+TCRb+CD8– cell; thymus' | cell type, genotype, organism part | Transcription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells |
-2.3 | | Npnt | 'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
2.3 | | Npnt | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
2.3 | | Npnt | '6 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
2.3 | | Npnt | 'osteoblast culture 9 day' vs '0 day' | time | Transcription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation |
2.3 | | Npnt | 'Yin Yang 1 (YY1) knockout' vs 'wild type' | genotype | Expression data from mouse skeletal muscle |
2.3 | | Npnt | 'colitis' at '12 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
2.3 | | Npnt | 'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-2.3 | | Npnt | 'Hunk knockout' vs 'wild type genotype' | genotype | Transcription profiling by array of mammary gland tissues from Hunk (a novel SNF1/AMPK-related protein kinase) knockout and wild type controls |
2.3 | | Npnt | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
2.3 | | Npnt | 'dorsolateral nucleus motor neuron' vs 'lumbar motor neurons' | cell type | Comparison of gene expression in motor pools with differential vulnerability in ALS |
-2.2 | | Npnt | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-2.2 | | Npnt | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-2.2 | | Npnt | '21 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
2.2 | | Npnt | 'transgenic' vs 'wild type' in '121 day; 129Sv' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
2.2 | | Npnt | 'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
2.2 | | Npnt | 'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '30 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
-2.1 | | Npnt | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
2.1 | | Npnt | 'tristetrapolin knockout' vs 'wild type' in 'none' at '0 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
2.1 | | Npnt | 'overexpression of SRC-2' vs 'control' | phenotype | A pivotal role of SRC-2 in Metastatic and Castration Resistant Prostate Cancer |
2.1 | | Npnt | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-2.1 | | Npnt | 'SARS coronavirus MA15 E protein mutant Δ5' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
2.1 | | Npnt | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-2 | | Npnt | 'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
2 | | Npnt | '5-aza-2'-deoxycytidine; 5 micromolar' vs 'none' | compound | Transcription profiling by array of mouse primary dermal fibroblasts after treatment with 5-aza-2'-deoxycytidine |
-2 | | Npnt | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-2 | | Npnt | 'spontaneous lung tumor' vs 'normal' | disease state, disease | Transcription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer |
-2 | | Npnt | 'SARS coronavirus MA15' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-2 | | Npnt | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
-1.9 | | Npnt | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
1.9 | | Npnt | 'overexpression of alpha- and beta- Hb chains' vs 'control vector' | genotype | Unexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells |
-1.9 | | Npnt | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
-1.9 | | Npnt | '10 week' vs '2 week' | time | Transcription profiling by array of mouse pre-frontal cortex at different time-points after birth |
-1.9 | | Npnt | 'carcinoma' vs 'normal' | disease | Gene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse |
1.9 | | Npnt | 'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 18.5' | cell type, developmental stage | Transcriptional regulation of endocrine cell differentiation by Insm1 |
1.9 | | Npnt | 'osteoblast culture 27 day' vs '0 day' | time | Transcription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation |
-1.9 | | Npnt | 'SARS coronavirus MA15 dORF6' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1.9 | | Npnt | 'high fat diet' vs 'chow diet' in 'SHP knockout' | genotype, growth condition | Transcription profiling of small heterodimer partner deficiency (SHP) knockout mice heart |
-1.9 | | Npnt | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.9 | | Npnt | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.9 | | Npnt | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1.9 | | Npnt | 'K-ras mutant' vs 'wild type' | genotype | Transcription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts |
1.9 | | Npnt | 'Nr1d1 homozygous knockout' vs 'wild type genotype' in 'methyl beta-clodextrin; 1 milligram per kilogram; ZT6' | compound, genotype, time | RNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment |
1.9 | | Npnt | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'inguinal fat pad' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
1.9 | | Npnt | 'Lgr6-positive hair follicle/sebaceous gland cell' vs 'basal keratinocyte' | cell type | Transcription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle |
-1.9 | | Npnt | 'SARS coronavirus MA15 lacking full-length E protein' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1.9 | | Npnt | 'extracellular vesicle; non-stimulated culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-1.8 | | Npnt | 'Duchenne muscular dystrophy' vs 'normal' | disease | RNA-seq comparison of immortalised myoblasts from dystrophic and WT mice |
-1.8 | | Npnt | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.8 | | Npnt | 'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1.8 | | Npnt | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.8 | | Npnt | 'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
-1.8 | | Npnt | 'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.8 | | Npnt | 'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day' | compound, genotype, time | Transcription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin |
1.8 | | Npnt | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
1.8 | | Npnt | 'left ventricle' vs 'right ventricle' in 'embryonic day 18.5' | developmental stage, organism part | Transcriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome |
-1.8 | | Npnt | 'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; lipopolysaccharide; 10 nanogram per milliliter' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.7 | | Npnt | 'interferon gamma; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
1.7 | | Npnt | 'intestinal smooth muscle culture supernatant' vs 'none' in 'organoid culture without Noggin (ER medium)' | growth condition, stimulus | RNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant |
1.7 | | Npnt | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'biliary-derived proliferative ducts (bilDP)' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
-1.7 | | Npnt | 'doxycycline; 200 nanogram per milliliter; neoplasm; 12 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.7 | | Npnt | 'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
1.7 | | Npnt | 'transgenic' vs 'wild type' in '160 day; C57BL/6' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
-1.7 | | Npnt | 'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
1.7 | | Npnt | '11beta-HSD knockout' vs 'wild type' in 'subcutaneous adipose tissue' | genotype, organism part | Transcription profiling of adipose tissue from mesenteric and subcutaneous depots from 11beta-HSD1 knockout and wild type mice |
-1.6 | | Npnt | 'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
1.6 | | Npnt | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
1.6 | | Npnt | 'Meis1; Meis2 conditional knockout' vs 'wild type phenotype' | phenotype | Meis homeobox genes control cell competence within the eye-specified neuroepithelium (RNA-seq) |
-1.6 | | Npnt | 'bevacizumab' vs 'control' | compound | Gene expression profile of U87-EV human glioblastoma xenograft tumours treated with bevacizumab or dibenzazepine |
-1.6 | | Npnt | 'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
-1.6 | | Npnt | 'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
1.6 | | Npnt | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1.6 | | Npnt | 'total RNA; HRasV12 and c-Myc overexpression and Eif4e heterozygous knockout' vs 'total RNA; wild type' | fraction, genotype | Redefining the role of eIF4E dose in development, cancer, and protein synthesis |
1.6 | | Npnt | 'Wt1-null' vs 'wild type' | genotype | Transcription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts |
-1.6 | | Npnt | 'Pcl2 knockdown' vs 'control' | genotype | Gene expression profile in mouse embryonic stem cells in which endogenous Pcl2 expression was stably knocked down using short hairpin RNA |
-1.5 | | Npnt | 'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
-1.5 | | Npnt | 'interleukin-22 (Mus Musculus); 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1.5 | | Npnt | 'reduced expression of miR-25' vs 'wild type' | phenotype | Transcription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice |
1.5 | | Npnt | '0.45 micromolar; 5-fluourouracil' vs 'none' at '24 hour' | compound, time | Transcription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid |
1.5 | | Npnt | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
-1.5 | | Npnt | 'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
-1.5 | | Npnt | 'wild type; SARS MA15; 2 day' vs 'wild type; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
-1.5 | | Npnt | '4 week' vs '2 week' | time | Transcription profiling by array of mouse pre-frontal cortex at different time-points after birth |
-1.5 | | Npnt | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.5 | | Npnt | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-1.5 | | Npnt | 'Influenza A virus' vs 'none' | infect | RNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals |
-1.5 | | Npnt | '14 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-1.5 | | Npnt | 'Mycobacterium tuberculosis; DBA/2J congenic; 30 day' vs 'control; DBA/2J congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.5 | | Npnt | 'Stella knockout' vs 'wild type genotype' in 'oocyte' | developmental stage, genotype | Transcription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development |
1.5 | | Npnt | 'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-1.5 | | Npnt | 'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-1.5 | | Npnt | 'Hnf1a knock out' vs 'wild type' | genotype | Transcription profiling of pancreatic islets from Hnf1a-deficient and wild type mice |
1.5 | | Npnt | 'conditional UPF2 knockout; before partial hepatechtomy' vs 'control; before partial hepatechtomy' | genotype, sampling time | Transcription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy |
1.5 | | Npnt | 'Nutlin-3a; 150 milligram per kilogram per day' vs 'none' in 'p53 heterozygous mutant' | compound, phenotype | RNA-seq of mouse colon to investigate how suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity |
-1.5 | | Npnt | 'ductus arteriosis' vs 'aorta' | organism part | Gene Profiling in Mouse Fetal Ductus Arteriosus |
1.5 | | Npnt | 'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
1.5 | | Npnt | 'oculomotor nucleus motor neurons' vs 'lumbar motor neurons' | cell type | Comparison of gene expression in motor pools with differential vulnerability in ALS |
1.5 | | Npnt | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.5 | | Npnt | 'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 15.5' | cell type, developmental stage | Transcriptional regulation of endocrine cell differentiation by Insm1 |
1.5 | | Npnt | 'K-ras mutant/Wt1-null' vs 'wild type' | genotype | Transcription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts |
1.4 | | Npnt | 'Sip1 knock out' vs 'wild type' | genotype | Sip1 in cortical interneuron migration |
-1.4 | | Npnt | 'KrasG12D' vs 'wild type' | genotype | An oncogenic Kras expression signature identified by cross-species |
-1.4 | | Npnt | '30 days of tuberculosis' vs 'uninfected' | disease, time | Transcription profiling by array of lungs from mice infected with tuberculosis |
1.4 | | Npnt | 'Med1 knockout' vs 'wild type' in 'ventral prostate' | genotype, organism part | Changes in gene expression caused by loss of Med1 in the mouse prostate |
1.4 | | Npnt | 'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'separate' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
-1.4 | | Npnt | '5,9-endoperoxy-cholest-7-en-3β,6α-diol' vs 'vehicle (cyclodextrin)' | compound, time | Array results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol |
-1.4 | | Npnt | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
1.4 | | Npnt | 'wild type; mature luminal' vs 'wild type; MaSC/basal' | cell type, genotype | Expression data from sorted control and Pygo2-null mouse mammary stem/basal cells |
-1.4 | | Npnt | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.4 | | Npnt | 'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
1.4 | | Npnt | 'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype' | genotype | Antibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq |
-1.4 | | Npnt | 'Hnf4a-pKO;Hnf1aHET double mutant' vs 'wild type genotype' | genotype | Transcription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice |
1.4 | | Npnt | 'intermittent fasting every 16 hours' vs 'ad libitum' | diet | Genome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver |
1.4 | | Npnt | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1.4 | | Npnt | 'shRNA mediated depletion of TUNA' vs 'control' at '4 day' | time, treatment | Transcriptome Analysis of LincRNA TUNA Knockdown in Mouse Embryonic Stem Cells |
-1.4 | | Npnt | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1.4 | | Npnt | 'cardiotoxin; 40 microliter' vs 'none' in 'MLC-CnAb1 overexpression' at '12 day' | compound, genotype, time | Transcription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin |
1.4 | | Npnt | 'Fhl1 knockdown by siRNA' vs 'wild type' at '3 day' | phenotype, time | 3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1 |
1.3 | | Npnt | 'Adrb1, Adrb2 and Adrb3 knockout' vs 'wild type genotype' in '20 to 22 degree celsius' | genotype, temperature | RNA-seq of cold-induced transcriptome changes in skeletal muscle of beta-adrenergic receptor knockout mice |
-1.3 | | Npnt | 'Irgm1 knockout' vs 'wild type genotype' in 'bone marrow' | genotype, organism part | RNA-Seq of bone marrow derived macophages (BMDMs) and brain tissue isolated from wild type and Irgm1 knockout mice |
-1.3 | | Npnt | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.3 | | Npnt | 'West Nile virus; late stage encephalitis' vs 'mock infection' | infect, time | Transcriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection |
-1.3 | | Npnt | 'cut nerve; 7 day' vs 'none' | injury, protocol, time | Changes in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury |
-1.3 | | Npnt | 'PPARgamma2 overexpression' vs 'empty vector' at '10 day' | genotype, time | Transcription profiling by array of mouse NIH3T3 cells over-expressing PPARg pr EBF1 over time |
-1.3 | | Npnt | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
-1.3 | | Npnt | 'neuron' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
-1.3 | | Npnt | '3 week' vs '2 week' | time | Transcription profiling by array of mouse pre-frontal cortex at different time-points after birth |
-1.3 | | Npnt | '5 week' vs '2 week' | time | Transcription profiling by array of mouse pre-frontal cortex at different time-points after birth |
-1.3 | | Npnt | 'acute oropharyngeal candidiasis' vs 'healthy' in wild type mice | compound, disease, genotype, sex | Transcription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis |
-1.3 | | Npnt | 'Lkb1 -/- Pten-/-' vs 'wild type' | genotype | Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells |
-1.3 | | Npnt | 'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 30 day' vs 'control; D2.B6-Chr19 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.3 | | Npnt | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1.3 | | Npnt | 'TGFβ, 5 nanogram per milliliter' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-1.3 | | Npnt | 'V6.5; embryonic stem cell’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
-1.3 | | Npnt | 'PAI1 knockout; SARS MA15; 4 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.3 | | Npnt | 'CD2314' vs 'none' at '6 day' | age, compound | Transcription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors |
-1.3 | | Npnt | '30 month' vs '5 month' in 'male' | age, block, sex | Expression data from tail skin in young (5 months) and old (30 months) CB6F1 mice |
-1.3 | | Npnt | 'doxycycline-induced inactivation of ErbB3' vs 'ErbB3 expression' | phenotype | Transcription profiling by array of mouse mammary epithelial organoids after doxycyline-induced repression of ErbB3 expression |
1.3 | | Npnt | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-1.3 | | Npnt | 'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '12 month' | age, genotype | ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression] |
-1.3 | | Npnt | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.2 | | Npnt | 'Drosha -/-' vs 'wild type genotype' | genotype | RNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs |
-1.2 | | Npnt | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.2 | | Npnt | 'R6/2' vs 'wild type genotype' | genotype | Gene expression data from cortex of 15 week old wild type, R6/2, HDAC4het and R6/2::HDAC4het mice |
1.2 | | Npnt | 'Mettl6 knockout clone D1' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
1.2 | | Npnt | 'Adrb1, Adrb2 and Adrb3 knockout' vs 'wild type genotype' in '15 degree celsius' | genotype, temperature | RNA-seq of cold-induced transcriptome changes in skeletal muscle of beta-adrenergic receptor knockout mice |
1.2 | | Npnt | '3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
-1.2 | | Npnt | 'wild type genotype; SARS MA15; 7 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.2 | | Npnt | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.2 | | Npnt | 'MG132; 1 micromolar' vs 'DMSO' in 'CHOP-/-' | compound, genotype | Microarray to find CHOP dependent genes in response to proteasome inhibition |
1.2 | | Npnt | 'Tgfbeta 1 ligand 0.04 nanogram per milliliter' vs 'none' | compound | Expression data from intestinal organoids altered for Tgfbeta signaling |
-1.2 | | Npnt | 'anti mTNF-alpha; 250 microgram' vs 'saline' in 'wild type; Mycobacterium tuberculosis H37Rv' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
1.2 | | Npnt | 'Crx knockout' vs 'control' at '6 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
-1.2 | | Npnt | 'Metarhizium anisopliae crude antigen' vs 'vehicle' at '12 hour' | compound, time | Transcription profiling of mouse lungs following exposure to agents of high or low allergenicity |
-1.2 | | Npnt | 'postnatal day 21; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1.2 | | Npnt | 'Klf5 knockout' vs 'wild type Klf5' | genotype | Expression data from conditional Klf5 knockout Pten-null mouse prostates |
-1.2 | | Npnt | 'GW501516' at '48 hour' vs 'none' | compound, time | PPARd target genes in MEFs |
1.2 | | Npnt | 'aire knock out' vs 'wild type' | genotype | Transcription profiling by array of mice mutant for aire |
-1.2 | | Npnt | 'TIMP1 knockout; SARS MA15; 4 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.2 | | Npnt | 'transgenic' vs 'wild type' in '133 day; C57BL/6' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
1.2 | | Npnt | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
-1.2 | | Npnt | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.2 | | Npnt | 'doxycycline-induced expression of NGN3' vs 'control' at '24 hour' | time, treatment | Transcription profiling by array of mouse embryonic stem cells expressing the transcription factor NGN3 for 12 hours, 24 hours and 48 hours |
-1.2 | | Npnt | 'miR-155 knockout' vs 'wild type' in 'natural killer cell' | cell type, genotype | Context- and cell-type specific function of miR155-Socs1 interaction in immune regulation |
-1.2 | | Npnt | '19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
1.2 | | Npnt | 'InsR, Igf1R double knockout' vs 'wild type' in 'postnatal day 5' | developmental stage, genotype | Transcriptional profiling by array of mouse wild-type and Insulin receptor (InsR)/Igf1 receptor (Igf1R) double knockout mutant Sertoli cells from testis at embryonic day E17.5 and Postnatal day 5 |
1.2 | | Npnt | 'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
-1.1 | | Npnt | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'endothelial cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
1.1 | | Npnt | 'Cnot3 knockout' vs 'wild type' | phenotype | RNA-seq of mouse islets from Ins1-cre driven Cnot3 KO and control islets |
-1.1 | | Npnt | 'N-acetylcysteine; 7 day differentiated; 1 millimolar' vs 'none; 7 day differentiated' | compound, developmental stage | RNA-seq of C17.2 neuronal progenitor cells exposed to cerium oxide nanoparticles during cell differentiation |
-1.1 | | Npnt | 'Mycobacterium tuberculosis H37Rv' vs 'none' | infect | The global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice |
-1.1 | | Npnt | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.1 | | Npnt | 'HDAC4het' vs 'wild type genotype' | genotype | Gene expression data from cortex of 15 week old wild type, R6/2, HDAC4het and R6/2::HDAC4het mice |
-1.1 | | Npnt | 'LKB1 knockout; floxed LKB1 with RIP-Cre' vs 'floxed LKB1 without RIP-Cre; wild type' | genotype, phenotype | Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice |
1.1 | | Npnt | 'Sall4 ZFC4mut' vs 'wild type genotype' | genotype | RNA-Seq of Sall4 mutants in mouse embryonic stem cells |
-1.1 | | Npnt | 'organoid culture without Noggin (ER medium)' vs 'organoid culture (ENR medium)' in 'none' | growth condition, stimulus | RNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant |
-1.1 | | Npnt | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.1 | | Npnt | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.1 | | Npnt | 'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 70 day' vs 'control; D2.B6-Chr7 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
-1.1 | | Npnt | 'R6/2 transgenic' vs 'wild type' in '12 week; brain cortex' | age, genotype, organism part | Transcription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks. |
1.1 | | Npnt | 'Lmna G609G/G609G knock in' vs 'wild type' | genotype | Transcription profiling by array of mouse liver with Lmna Gly609Gly knock in |
-1.1 | | Npnt | '3 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-1.1 | | Npnt | 'Influenza A virus' vs 'mock' in 'interleukin-22' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
-1.1 | | Npnt | 'tumor' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
1.1 | | Npnt | 'CD36 knockout' vs 'wild type genotype' in 'none' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
1.1 | | Npnt | 'mdx' vs 'wild type' in 'postnatal day 23' | developmental stage, genotype | Transcription profiling of mouse hindlimb muscle, comparison of wild type and mdx mice, 7 to 112 Day |
-1.1 | | Npnt | '70 days of tuberculosis' vs 'uninfected' | disease, time | Transcription profiling by array of lungs from mice infected with tuberculosis |
-1.1 | | Npnt | 'E2f1, E2f2, E2f3 triple knockout' vs 'control' at 'neonate' | developmental stage, genotype | Expression data from lenses triply deficient for E2F1, E2F2, and E2F3 transcription factors |
-1.1 | | Npnt | 'acute oropharyngeal candidiasis wild type mice'; female' vs 'healthy wild type genotype mice' | compound, disease, genotype, sex | Transcription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis |
-1.1 | | Npnt | 'early B-cell factor 1 overexpression' vs 'empty vector' at '4 day' | genotype, time | Transcription profiling by array of mouse NIH3T3 cells over-expressing PPARg pr EBF1 over time |
1.1 | | Npnt | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Transcription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa |
-1.1 | | Npnt | 'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-1.1 | | Npnt | 'pkd1 knockout' vs 'wild type' in 'presence of fluid flow' | genotype, stimulus | Transcription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow |
-1.1 | | Npnt | 'H-Ras expression; c-Myc activation' vs 'wild type' | phenotype | RNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls. |
-1.1 | | Npnt | '100 nanomolar endothelin-1' vs 'none' | compound | Transcription profiling by array of mouse primary dermal fibroblasts after treatment with endothelin-1 |
-1.1 | | Npnt | 'endothelin-1' vs 'control' | compound | Transcription profiling of mouse dermal fibroblasts following exposure to endothelin-1 |
-1.1 | | Npnt | 'Nix knock out' vs 'wild type' | genotype | Transcription profiling by array of spleens from mice with Nix knocked out. |
-1.1 | | Npnt | 'fear conditioning' vs 'none' | stimulus | Gene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage |
1.1 | | Npnt | 'untreated; Csf2rb-/-' vs 'untreated; wild type' | clinical history, genotype | Mouse GM-CSF-related alveolar macrophage genome-wide expression data |
1.1 | | Npnt | 'beta(3)-adrenergic agonist Cl316,243' vs 'none' at '10 week' | age, stimulus | RNA-seq of age-associated transcriptome changes in brown adipose tissue |
-1 | | Npnt | 'AMPK double knockout; floxed AMPK alpha 1 and 2 with Ins1-Cre' vs 'floxed AMPK without Ins1-Cre; wild type' | genotype, phenotype | Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice |
-1 | | Npnt | 'K14-Cre-ERT2; none; UVB irradiation; 7 day' vs 'K14-Cre-ERT2; none; none' | genotype, irradiate, time | Ablation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin |
1 | | Npnt | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1 | | Npnt | 'epithelium-specific mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1 | | Npnt | 'anti-CD3/anti-CD28' vs 'none' in 'empty vector' | genotype, stimulus | Transcription profiling by array of FOXP3 overexpression in resting and activated mouse CD4+ T cells |
1 | | Npnt | 'ReverbαFlox2-6AdipoCre+' vs 'ReverbαFlox2-6AdipoCre-' in 'normal chow; 28 week' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
-1 | | Npnt | '10 day' vs '0 day' | age | Transcriptional profiling by array of mouse cerebellar cortex during postnatal development |
-1 | | Npnt | 'MG132; 1 micromolar' vs 'DMSO' in 'wild type' | compound, genotype | Microarray to find CHOP dependent genes in response to proteasome inhibition |
-1 | | Npnt | '24 hour' vs '0 hour' in 'WT1-KTS' | genotype, time | EWS-WT1 Oncogene Activates a Neuronal Reprogramming Factor ASCL1 and Mediates Partial Neural Differentiation |
-1 | | Npnt | 'rosiglitazone; 100 nanomolar' vs 'none' in 'wild type genotype' | compound, genotype | Transcriptional response to Rosiglitazone in adipocyte progenitors isolated from WT and Cited4-KO scWAT |
1 | | Npnt | 'injected with sperm-derived RNA fragments from mice subjected to early life stress (MSUS)' vs 'injected with sperm-derived RNA fragments from control non-stressed mice' | stimulus | Zygotic expression after parental early life stress |
-1 | | Npnt | 'TIMP1 knockout; SARS MA15; 7 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1 | | Npnt | 'rosiglitazone; 100 nanomolar' vs 'none' in 'Cited4-/-' | compound, genotype | Transcriptional response to Rosiglitazone in adipocyte progenitors isolated from WT and Cited4-KO scWAT |
-1 | | Npnt | '7 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-1 | | Npnt | 'shRNA p68/p72 knockdown; differentiated' vs 'control; differentiated' on 'Affymetrix Array MOE430A' | RNA interference, developmental stage | Transcription profiling of p68/72 deficient C2C12 cells to investigate the function of p68/p72 in muscle gene expression and skeletal C2C12 cell differentiation. |
1 | | Npnt | '20 day; Ad-VEGF-A164' vs '0 day; control' | time, treatment | Transcription profiling by array of stromal-based signatures for the classification of gastric cance |
1 | | Npnt | 'adipose tissue specific Trim28 knockout' vs 'wild type genotype' in 'male' | genotype, sex | RNA-seq of gonadal adipose tissue from male and female Trim28-WT and Trim28 adipose specific KO mice |
-1 | | Npnt | '3 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
-1 | | Npnt | 'PGC-1 beta knock in' vs 'wild type' | genotype | Transcription profiling by array of skeletal muscle from PGC-1 beta transgenic mice |
1 | | Npnt | 'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'control; 36 hour after partial hepatechtomy' | genotype, sampling time | Transcription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy |
1 | | Npnt | 'transgenic' vs 'wild type' in '152 day; C57BL/6' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
1 | | Npnt | 'H9; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
1 | | Npnt | 'SARS coronavirus MA15 nsp16 -/-' vs 'SARS coronavirus MA15' at '7 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1 | | Npnt | 'high fat diet' vs 'chow diet' in 'wild type' | genotype, growth condition | Transcription profiling of small heterodimer partner deficiency (SHP) knockout mice heart |
-1 | | Npnt | 'miR-34a overexpression' vs 'control' | phenotype | Transcriptional profiling of lung cancer cells over-expression miR-34a. |
1 | | Npnt | 'high fat' vs 'chow' in 'NZO/HILtJ' | diet, strain | Transcription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ |
-1 | | Npnt | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1 | | Npnt | 'CD4-CRE+ (PPAR g null)' vs 'wild type genotype' at '2 day' | genotype, time | Transcription profiling by array of mouse Peroxisome proliferator-activated receptor g (PPARg) null CD4+ T cells after treatment with dextran-sodium sulfate for 2 or 7 days to induce colitis |