ENSMUSG00000049511 (Htr1b)

mus musculus

5-hydroxytryptamine (serotonin) receptor 1B

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Mus musculus
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Showing 2 experiments:
Created with Highcharts 6.2.0adult CCAP neuronalpha’/beta’ middle Kenyon cellcentrifugal neuron C3distal medullary amacrine neuron Dm10distal medullary amacrine neuron Dm9dopaminergic PAM neuron 6gamma dorsal Kenyon celllamina monopolar neuron L2lobula columnar neuron LC10alobula columnar neuron LC6lobula-lobula plate columnar neuron LLPC1mushroom body output neuronproximal medullary amacrine neuron Pm3transmedullary neuron Tm1transmedullary neuron Tm4adult lamina marginal glial cellalpha/beta posterior Kenyon cellcolumnar neuron T1distal medullary amacrine neuron Dm3dopaminergic PAM neuron 3dopaminergic PAM neuron 9lamina intrinsic neuronlamina monopolar neuron L5lobula columnar neuron LC10dlobula plate tangential neuronmedullary intrinsic neuron Mi4photoreceptor cell R7T neurontransmedullary neuron Tm29
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
2.3686 × 10-15-8
Htr1b'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
5.2912 × 10-66.9
Htr1b'neural stem cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
7.6432 × 10-8-6.7
Htr1b'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
4.2964 × 10-42-6
Htr1b'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
9.814 × 10-42-6
Htr1b'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.3952 × 10-314.9
Htr1b'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
1.4283 × 10-144.9
Htr1b'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
4.2743 × 10-31-4.8
Htr1b'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.0181 × 10-124.1
Htr1b'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
4.516 × 10-224
Htr1b'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
3.8496 × 10-113.8
Htr1b'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.7623 × 10-43.6
Htr1b'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.339 × 10-143.5
Htr1b'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
2.4605 × 10-133.5
Htr1b'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
3.6218 × 10-93.5
Htr1b'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
6.295 × 10-93.5
Htr1b'NOD' vs 'C57BL/6' in 'steady state' at '0 hour'strain, time, treatmentExpression data from NOD and C57BL/6 mouse pancreas CD8α- Dendritic Cells (DCs) under steady-state and after in-vitro LPS stimulation
Adjusted p-valueLog2-fold change
4.8379 × 10-3-3.5
Htr1b'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.8937 × 10-63.4
Htr1b'RAW264.7 macrophage cell line; control' vs 'bone marrow macrophage; control'cell type, growth conditionTranscription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line
Adjusted p-valueLog2-fold change
9.0546 × 10-43.4
Htr1b'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.0015 × 10-3-3.4
Htr1b'total RNA; HRasV12 and c-Myc overexpression and Eif4e wild type' vs 'total RNA; wild type'fraction, genotypeRedefining the role of eIF4E dose in development, cancer, and protein synthesis
Adjusted p-valueLog2-fold change
2.8233 × 10-33.4
Htr1b'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
3.5098 × 10-223.2
Htr1b'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
4.3815 × 10-43.1
Htr1b'acute myeloid leukemia' vs 'myeloproliferative disorder'diseaseTranscription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm
Adjusted p-valueLog2-fold change
1.9024 × 10-33
Htr1b'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
6.6432 × 10-32.9
Htr1b'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
3.5807 × 10-72.8
Htr1b'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
4.7485 × 10-62.8
Htr1b'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.8452 × 10-32.8
Htr1b'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
4.2026 × 10-22.8
Htr1b'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.8524 × 10-162.7
Htr1b'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
9.0699 × 10-7-2.6
Htr1b'inhibition of BRD4 with JQ1' vs 'DMSO'treatmentExpression Data For BRD4 Inhibition
Adjusted p-valueLog2-fold change
1.0446 × 10-3-2.6
Htr1b'3D culture' vs '2D culture'growth conditionmRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture
Adjusted p-valueLog2-fold change
2.3012 × 10-3-2.6
Htr1b'polysomal RNA; HRasV12 and c-Myc overexpression and Eif4e wild type' vs 'polysomal RNA; wild type'fraction, genotypeRedefining the role of eIF4E dose in development, cancer, and protein synthesis
Adjusted p-valueLog2-fold change
1.7866 × 10-22.6
Htr1b'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
2.1901 × 10-302.5
Htr1b'Sall4 -/-' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells in response to changes in Sall4
Adjusted p-valueLog2-fold change
5.8803 × 10-7-2.4
Htr1b'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
1.9512 × 10-42.4
Htr1b'old neuronal stem cells' vs 'young neuronal stem cells'ageA mechanism for the segregation of age in mammalian neural stem cells
Adjusted p-valueLog2-fold change
4.7686 × 10-3-2.4
Htr1b'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.8149 × 10-22.4
Htr1b'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
8.1781 × 10-8-2.3
Htr1b'MyD88 homozygous knockout' vs 'wild type genotype' in 'TLR9 ligand CpG ODN (1826)'genotype, stimulusTranscription profiling by sequencing of murine MyD88 -/- and MyD88 +/+ mTECs stimulated with a TLR9 ligand
Adjusted p-valueLog2-fold change
5.16 × 10-62.3
Htr1b'12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
1.5158 × 10-2-2.3
Htr1b'cut nerve; 7 day' vs 'none'injury, protocol, timeChanges in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury
Adjusted p-valueLog2-fold change
2.2139 × 10-272.2
Htr1b'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
6.5438 × 10-62.2
Htr1b'Mettl6 knockout clone D1' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
1.3136 × 10-3-2.1
Htr1b'total RNA; HRasV12 and c-Myc overexpression and Eif4e heterozygous knockout' vs 'total RNA; wild type'fraction, genotypeRedefining the role of eIF4E dose in development, cancer, and protein synthesis
Adjusted p-valueLog2-fold change
2.0615 × 10-22.1
Htr1b'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
2.1745 × 10-2-2.1
Htr1b'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
9.1652 × 10-8-2
Htr1b'induced neural stem cell' vs 'mouse embryonic fibroblast cell'cell typeGene expression profile of mouse induced neural stem cells
Adjusted p-valueLog2-fold change
1.059 × 10-5-2
Htr1b'shRNA mediated Brd4 knockdown' vs 'control shRNA'treatmentExpression Data For BRD4 Inhibition
Adjusted p-valueLog2-fold change
1.6374 × 10-52
Htr1b'Mettl6 knockout clone G6' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
5.0472 × 10-4-2
Htr1b'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
3.1992 × 10-31.8
Htr1b'lung carcinoma' vs 'normal' in 'lung cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
7.6688 × 10-31.8
Htr1b'fear conditioning' vs 'none'stimulusGene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage
Adjusted p-valueLog2-fold change
1.3326 × 10-21.8
Htr1b'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'white adipose tissue'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
1.5187 × 10-2-1.8
Htr1b'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
4.6486 × 10-21.8
Htr1b'Wt1-null' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
3.4925 × 10-6-1.7
Htr1b'24 hour' vs '0 hour' in 'WT1-KTS'genotype, timeEWS-WT1 Oncogene Activates a Neuronal Reprogramming Factor ASCL1 and Mediates Partial Neural Differentiation
Adjusted p-valueLog2-fold change
5.421 × 10-31.7
Htr1b'Crx knockout' vs 'control' at '20 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
4.1601 × 10-2-1.7
Htr1b'ICG-001' vs 'DMSO'compoundTranscription profiling by array of mammospheres derived from tumors of mice harboring Wnt/Met signaling mutations treated Wnt and MET pathway inhibitors
Adjusted p-valueLog2-fold change
1.415 × 10-281.6
Htr1b'Sall4 ZFC4mut' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
4.155 × 10-5-1.6
Htr1b'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1'cell type, growth condition, phenotypeTranscription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture
Adjusted p-valueLog2-fold change
3.462 × 10-4-1.6
Htr1b'Kras G12D' vs 'wild type'genotypeLoss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells
Adjusted p-valueLog2-fold change
3.5458 × 10-31.6
Htr1b'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
3.8964 × 10-2-1.6
Htr1b'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
4.2525 × 10-41.5
Htr1b'K14-Cre-ERT2; none; UVB irradiation; 7 day' vs 'K14-Cre-ERT2; none; none'genotype, irradiate, timeAblation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin
Adjusted p-valueLog2-fold change
4.4051 × 10-41.5
Htr1b'NOD' vs 'C57BL/6' in 'LPS stimulation' at '18 hour'strain, time, treatmentExpression data from NOD and C57BL/6 mouse pancreas CD8α- Dendritic Cells (DCs) under steady-state and after in-vitro LPS stimulation
Adjusted p-valueLog2-fold change
3.2061 × 10-71.4
Htr1b'IRAK1BP1 KO' vs 'wild type' in 'TNFα'genotype, treatmentIdentification of TNFα-induced genes that are IRAK1BP1 dependent
Adjusted p-valueLog2-fold change
7.3333 × 10-71.4
Htr1b'MEF; transduced with NeuroD2 lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
9.6721 × 10-5-1.4
Htr1b'Lkb1 -/- Pten-/-' vs 'wild type'genotypeLoss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells
Adjusted p-valueLog2-fold change
3.0312 × 10-4-1.4
Htr1b'Trp53 Arg178Asp' vs 'wild type genotype' in 'dimethyl sulfoxide; 0.1 microliter'compound, phenotypeResidual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy
Adjusted p-valueLog2-fold change
3.6186 × 10-41.4
Htr1b'Crx knockout' vs 'control' at '6 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
2.0638 × 10-31.4
Htr1b'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.1798 × 10-31.4
Htr1b'co-culture' vs 'separate' in 'Ink4a/Arf-/-; EGFRvIII'genotype, growth conditionRNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions
Adjusted p-valueLog2-fold change
4.5767 × 10-3-1.4
Htr1b'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
6.492 × 10-31.4
Htr1b'high GLUT1 expression' vs 'low GLUT1 expression' in 'wild type genotype'genotype, phenotypeRNA-seq analysis of normoxic and hypoxic tumor-associated macrophages from wild type or REDD1 knockout mice
Adjusted p-valueLog2-fold change
8.1445 × 10-31.4
Htr1b'Runx3 knockout' vs 'wild type genotype'genotypeRunx3 function in splenic NK cells
Adjusted p-valueLog2-fold change
1.0628 × 10-2-1.4
Htr1b'polysomal RNA; HRasV12 and c-Myc overexpression and Eif4e heterozygous knockout' vs 'polysomal RNA; wild type'fraction, genotypeRedefining the role of eIF4E dose in development, cancer, and protein synthesis
Adjusted p-valueLog2-fold change
1.1634 × 10-21.4
Htr1b'myelocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
1.6971 × 10-4-1.3
Htr1b'PUGKO' vs 'wild type'genotypeExpression profiling of the uteri of progesterone induced uterine gland knockout mice
Adjusted p-valueLog2-fold change
1.9704 × 10-4-1.3
Htr1b'PgrCre/+ Foxa2flox/flox' vs 'wild type'genotypeIdentification of candidate FOXA2-regulated genes in the adult mouse uterus
Adjusted p-valueLog2-fold change
8.724 × 10-4-1.3
Htr1b'Debaryomyces hansenii' at '24 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
3.3263 × 10-3-1.3
Htr1b"98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young"age, phenotypeRNAseq of whole ovarian follicles from young and old mice.
Adjusted p-valueLog2-fold change
1.9584 × 10-2-1.3
Htr1b'Trp53 Arg178Asp' vs 'wild type genotype' in 'Nutlin-3a; 10 micromolar'compound, phenotypeResidual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy
Adjusted p-valueLog2-fold change
2.5117 × 10-5-1.2
Htr1b'7 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
2.4752 × 10-3-1.2
Htr1b'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
2.6434 × 10-3-1.2
Htr1b'interferon gamma' vs 'dexamethasone; 100 nanomolar'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
6.3958 × 10-3-1.2
Htr1b'R6/2 transgenic' vs 'wild type' in '12 week; striatum'age, genotype, organism partTranscription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks.
Adjusted p-valueLog2-fold change
1.3745 × 10-2-1.2
Htr1b'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
2.4931 × 10-71.1
Htr1b'IRAK1BP1 KO' vs 'wild type' in 'none'genotype, treatmentIdentification of TNFα-induced genes that are IRAK1BP1 dependent
Adjusted p-valueLog2-fold change
7.3131 × 10-5-1.1
Htr1b'10 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
3.3095 × 10-2-1.1
Htr1b'stabilization-competent' vs 'stabilization-incompetent' in '22 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
6.8719 × 10-8-1
Htr1b'Sall4 ZFC1-2Δ' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
1.2021 × 10-5-1
Htr1b'Plasmodium berghei ANKA' at '7 day' vs 'none' at '0 day' in 'none'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
2.571 × 10-41
Htr1b'follicle stimulating hormone and epidermal growth factor' vs '293H control medium'growth conditionTranscription profiling by array of mouse cumulus cells after culture with growth differentiation factor 9 or follicle stimulating hormone and epidermal growth factor
Adjusted p-valueLog2-fold change
3.5999 × 10-4-1
Htr1b'4-hydroxytamoxifen-mediated deletion of Prmt5' vs 'wild type' in 'mouse neural progenitor cell'cell type, phenotypeTranscription profiling by high throughput sequencing of murine neural stem/progenitor cells lacking PRMT5 over control
Adjusted p-valueLog2-fold change
6.7079 × 10-3-1
Htr1b'interferon gamma' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
2.6055 × 10-2-1
Htr1b'ductus arteriosis' vs 'aorta'organism partGene Profiling in Mouse Fetal Ductus Arteriosus
Synonym
5-HT1B receptor, 5-HT<1B> receptor, 5HT1B receptor
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4357341, 4803442, A_55_P2290443, 5038156, 5236251, 1422288_at, 4362693, 1442077_at, 99411_at, 10595324, 4520938, ILMN_2628759, 4664074, A_52_P103998, 4858347, 4337464, Msa.1776.0_at, 17529218
Reactome pathway ID