ENSMUSG00000055116 (Arntl)

mus musculus

aryl hydrocarbon receptor nuclear translocator-like

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Duda et al., 2018 - organism part - …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Proteomics
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Transcriptomics
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Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.5788 × 10-25-4.9
Arntl'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.9858 × 10-53.5
Arntl'Lmna G609G/G609G knock in' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Lmna Gly609Gly knock in
Adjusted p-valueLog2-fold change
3.7174 × 10-253.1
Arntl'intermittent fasting every 16 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
7.666 × 10-4-3
Arntl'diet restriction' vs 'control'dietLiver mRNA microarray study for mice treated with various diets
Adjusted p-valueLog2-fold change
8.669 × 10-152.9
Arntl'ZT18' vs 'ZT6' in 'methyl beta-clodextrin; 1 milligram per kilogram; wild type genotype'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
2.5605 × 10-83-2.8
Arntl'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.8634 × 10-142.8
Arntl'ZT18' vs 'ZT6' in 'dexamethasome; 1 milligram per kilogram; wild type genotype'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
1.0192 × 10-82.7
Arntl'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
1.2167 × 10-22.7
Arntl'Gata6 knockout' vs 'wild type'phenotypeGlobal gene expression in the adult Gata6 null mouse pancreas
Adjusted p-valueLog2-fold change
1.5265 × 10-159-2.6
Arntl'IL17A homozygous knockout' vs 'wild type genotype' in 'ascending colon'genotype, organism partRNAseq analysis of colon and ileum tissue from naive wild type, MR1-/- and IL-17A-/- mice
Adjusted p-valueLog2-fold change
2.5502 × 10-62.5
Arntl'Nr1d1 homozygous knockout' vs 'wild type genotype' in 'methyl beta-clodextrin; 1 milligram per kilogram; ZT6'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
8.2838 × 10-52.5
Arntl'5 Gray; X-radiation' vs 'none' at '30 week'irradiate, timeSenescence gene signature of radiation fibrosis
Adjusted p-valueLog2-fold change
3.047 × 10-2-2.5
Arntl'mature cerebellum' vs 'developing cerebellum'organism partGlobal gene expression in individual Bergmann glia from developing (P6) and mature (P30) mouse cerebellum
Adjusted p-valueLog2-fold change
8.191 × 10-49-2.4
Arntl'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
3.5982 × 10-462.4
Arntl'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
7.1197 × 10-362.4
Arntl'Reverbα-/- global knockout' vs 'Reverbα wild type' in 'not applicable; 13 week'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
5.047 × 10-7-2.4
Arntl'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.8528 × 10-7-2.4
Arntl'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
7.7414 × 10-7-2.4
Arntl'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
9.6474 × 10-7-2.4
Arntl'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.3613 × 10-6-2.4
Arntl'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.2963 × 10-70-2.3
Arntl'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.6764 × 10-262.3
Arntl'Reverbα -/-' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
5.534 × 10-22-2.2
Arntl'21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
2.8977 × 10-5-2.2
Arntl'control; streptozotocin-induced diabetes' vs 'control; control'diet, phenotypeHepatic gene expression in streptozotocin-induced diabetic mice fed a phloridzin diet
Adjusted p-valueLog2-fold change
3.9855 × 10-52.2
Arntl'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
2.3862 × 10-32.2
Arntl'high fat diet' vs 'chow diet' in 'wild type'genotype, growth conditionTranscription profiling of small heterodimer partner deficiency (SHP) knockout mice heart
Adjusted p-valueLog2-fold change
1.2832 × 10-62.1
Arntl'Nr1d1-/-' vs 'wild type genotype'genotypeTranscription profiling by array of liver tissues from wild type and Rev-erb{alpha} knockout (Nr1d1-/-) mice to study direct targets of Nr1d1 in rhythmic (circadian) transcription
Adjusted p-valueLog2-fold change
3.8244 × 10-42.1
Arntl'Nr1d1 homozygous knockout' vs 'wild type genotype' in 'dexamethasome; 1 milligram per kilogram; ZT6'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
3.707 × 10-2-2.1
Arntl'Lgr6-positive hair follicle/sebaceous gland cell' vs 'Lgr6-positive basal interfollicular epidermis cell'cell typeTranscription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle
Adjusted p-valueLog2-fold change
3.1442 × 10-17-2
Arntl'21 percent oxygen, 37 degree Celsius, no serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
9.8396 × 10-7-2
Arntl'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
1.1538 × 10-6-2
Arntl'trinitrobenzene sulfonic acid' vs 'none' in 'wild type'compound, genotypeChronic TNBS Colitis in the FN14 KO Mouse
Adjusted p-valueLog2-fold change
8.406 × 10-52
Arntl'Rassf1a knockout' vs 'wild type'genotypeTranscription profiling by array of liver from Rassf1a homozygous knockout mice, heterozygous deletion of Sav1 and codeletion of Rassf1a and Sav1
Adjusted p-valueLog2-fold change
5.9821 × 10-42
Arntl'high fat diet' vs 'chow diet' in 'SHP knockout'genotype, growth conditionTranscription profiling of small heterodimer partner deficiency (SHP) knockout mice heart
Adjusted p-valueLog2-fold change
1.5789 × 10-2-2
Arntl'extensive self renewing erythroblast' vs 'restrictive self renewing erythroblast'cell typeRestrictive and extensively self-renewing erythroblast
Adjusted p-valueLog2-fold change
4.2309 × 10-30-1.9
Arntl'3 hour' vs '1 hour' in 'fetal bovine serum; 10 percent'growth condition, timeTranscriptomic changes in C3H10T1/2 cells exposed to lipid deprivation
Adjusted p-valueLog2-fold change
7.6525 × 10-81.9
Arntl'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
8.8603 × 10-61.9
Arntl'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
3.078 × 10-41.9
Arntl'fasted' vs 're-fed' in 'db/db; Gabpa miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
6.9719 × 10-4-1.9
Arntl'tumor' vs 'normal' in 'liver'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
4.1256 × 10-21.9
Arntl'renin-expression' vs 'control'phenotypeExpression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein.
Adjusted p-valueLog2-fold change
1.014 × 10-421.8
Arntl'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
1.0972 × 10-301.8
Arntl'6 hour' vs '3 hour' in 'fetal bovine serum; 10 percent'growth condition, timeTranscriptomic changes in C3H10T1/2 cells exposed to lipid deprivation
Adjusted p-valueLog2-fold change
2.3015 × 10-81.8
Arntl'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
2.2303 × 10-71.8
Arntl'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; STI571 treated' vs 'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; untreated'cell type, treatmentGene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice
Adjusted p-valueLog2-fold change
1.0136 × 10-5-1.8
Arntl'AAV9-Ccnt1;Myh6-cre;LSL-R26CAG-c-MycERT2/+' vs 'AAV9-Ccnt1;LSL-R26CAG-c-MycERT2/+'genotypeRNA-seq of purified cardiomocytes from adult mice (+/- AAV-CCNT1) 4 hours post MycER activation compared controls.
Adjusted p-valueLog2-fold change
1.6918 × 10-51.8
Arntl'smoke; 3000 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
4.1961 × 10-5-1.8
Arntl'heart-specific p53 and Mdm2 knockout; 1 day' vs 'wild type phenotype'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
4.6602 × 10-51.8
Arntl'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 2 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
8.3311 × 10-5-1.8
Arntl'30 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.2651 × 10-4-1.8
Arntl'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
3.8169 × 10-4-1.8
Arntl'Methylene Chloride; 4000 part per million; air' vs 'none; ; air'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
9.0695 × 10-41.8
Arntl'postnatal day 21; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
9.2551 × 10-3-1.8
Arntl'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.7339 × 10-61.7
Arntl'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
4.8129 × 10-61.7
Arntl'S-(1,2-dichlorovinyl)-L-cysteine; 15 milligram per kilogram; renal injury; 1 week' vs 'none; normal'compound, disease, timeExpression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC
Adjusted p-valueLog2-fold change
2.3815 × 10-41.7
Arntl'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; adult'cell type, developmental stageTranscription profiling of mouse adult and fetal T cell progenitors
Adjusted p-valueLog2-fold change
6.6593 × 10-4-1.7
Arntl'Stat5abfl/fl;MMTV-Cre' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
7.7167 × 10-41.7
Arntl'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
6.7065 × 10-31.7
Arntl'S6K1 knockout' vs 'wild type' in 'liver'genotype, organism partTranscription profiling of mouse long-lived S6K1 -/- strain females compared to wild types
Adjusted p-valueLog2-fold change
7.0514 × 10-31.7
Arntl'fasted' vs 're-fed' in 'db/db; control miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.9485 × 10-2-1.7
Arntl'20 hour' vs '4 hour'timeTranscription profiling of mouse rhythmic mRNA expression in the distal colon
Adjusted p-valueLog2-fold change
3.4364 × 10-2-1.7
Arntl'2-Chloromethylpyridine hydrochloride; 250 milligram per kilogram; distilled water' vs 'none; ; distilled water'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
4.4034 × 10-2-1.7
Arntl'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.0666 × 10-181.6
Arntl'all-trans-retinoic acid; 5 micromolar' vs 'none' in 'wild type phenotype'compound, phenotypeRNA Seq of control and Cyp26b1KO HSCs after 24h of in vitro culture and treatment
Adjusted p-valueLog2-fold change
7.0532 × 10-171.6
Arntl'4-oxoretinoic acid; 5 micromolar' vs 'none' in 'wild type phenotype'compound, phenotypeRNA Seq of control and Cyp26b1KO HSCs after 24h of in vitro culture and treatment
Adjusted p-valueLog2-fold change
4.5548 × 10-111.6
Arntl'ReverbαFlox2-6AdipoCre+' vs 'ReverbαFlox2-6AdipoCre-' in 'not applicable; 13 week'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
5.1808 × 10-7-1.6
Arntl'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
1.4167 × 10-6-1.6
Arntl'MEF; transduced with NeuroD2 lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
1.4491 × 10-51.6
Arntl'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
6.0889 × 10-51.6
Arntl'resolved cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
9.5057 × 10-41.6
Arntl'Rassf1a knockout, Sav1 heterozygous knockout' vs 'wild type'genotypeTranscription profiling by array of liver from Rassf1a homozygous knockout mice, heterozygous deletion of Sav1 and codeletion of Rassf1a and Sav1
Adjusted p-valueLog2-fold change
1.0835 × 10-31.6
Arntl'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
2.6969 × 10-31.6
Arntl'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
2.9258 × 10-3-1.6
Arntl'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.7998 × 10-2-1.6
Arntl'24 hour' vs '4 hour'timeTranscription profiling of mouse rhythmic mRNA expression in the distal colon
Adjusted p-valueLog2-fold change
4.1799 × 10-2-1.6
Arntl'CD2AP-/-' vs 'wild type genotype' in 'renal glomerular podocyte'cell type, genotypeTranscription profiling by array of three major cell types of the glomerulus (podocytes, mesangial cells and endothelial cells) from CD2AP-/- mutant mice and normal controls
Adjusted p-valueLog2-fold change
7.2995 × 10-151.5
Arntl'ReverbαFlox2-6AdipoCre+' vs 'ReverbαFlox2-6AdipoCre-' in 'normal chow; 28 week'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
3.3819 × 10-11-1.5
Arntl'human-Mfn2-overexpressing (Mfn2wt)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.4501 × 10-101.5
Arntl'anti-mIL-17A; 500 microgram' vs 'saline' in 'wild type; Mycobacterium tuberculosis H37Rv'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
1.4221 × 10-8-1.5
Arntl'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
6.5228 × 10-6-1.5
Arntl'granulocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
1.5139 × 10-51.5
Arntl'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
3.2784 × 10-5-1.5
Arntl'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 30 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
5.3416 × 10-51.5
Arntl'wild type; SARS MA15; 2 day' vs 'wild type; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
1.3573 × 10-41.5
Arntl'Lin- CD44- CD25+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44- CD25+ thymocyte progenitor cell; adult'cell type, developmental stageTranscription profiling of mouse adult and fetal T cell progenitors
Adjusted p-valueLog2-fold change
1.0528 × 10-31.5
Arntl'Lin- CD44+ CD25+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44+ CD25+ thymocyte progenitor cell; adult'cell type, developmental stageTranscription profiling of mouse adult and fetal T cell progenitors
Adjusted p-valueLog2-fold change
2.8379 × 10-3-1.5
Arntl'45 percent caloric restriction' vs 'control'dietGene expression profile from short-term caloric restriction in mouse adipose tissue
Adjusted p-valueLog2-fold change
4.3088 × 10-31.5
Arntl'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
9.606 × 10-3-1.5
Arntl'30 percent caloric restriction' vs 'control'dietGene expression profile from short-term caloric restriction in mouse adipose tissue
Adjusted p-valueLog2-fold change
4.094 × 10-21.5
Arntl'bER knockout' vs 'wild type' in 'human chorionic gonadotropin; 5 International Unit'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Adjusted p-valueLog2-fold change
1.8632 × 10-18-1.4
Arntl'15 degree celsius' vs '20 to 22 degree celsius' in 'wild type genotype'genotype, temperatureRNA-seq of cold-induced transcriptome changes in subcutaneous adipose tissue of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
1.1097 × 10-71.4
Arntl'4-oxoretinoic acid; 5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA Seq of wildtype and Rarb KO HSCs after 24h of in vitro culture and treatment
Adjusted p-valueLog2-fold change
4.6139 × 10-71.4
Arntl'all-trans-retinoic acid; 5 micromolar' vs 'none' in 'Rarb -/-'compound, genotypeRNA Seq of wildtype and Rarb KO HSCs after 24h of in vitro culture and treatment
Adjusted p-valueLog2-fold change
6.4835 × 10-61.4
Arntl'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
7.0855 × 10-61.4
Arntl'intermittent fasting every 24 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
8.2648 × 10-61.4
Arntl'SARS coronavirus MA15' vs 'none' at '2 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
2.7045 × 10-5-1.4
Arntl'mutant MyoD expression' at '24 hour' vs 'control' at '24 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
5.7232 × 10-5-1.4
Arntl'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 30 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
6.3671 × 10-4-1.4
Arntl'db/db' vs 'wild type genotype' in 'Gabpa miRNA; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.6003 × 10-3-1.4
Arntl'T-cell depleted bone marrow transplant' vs 'none' in 'normal'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
4.4896 × 10-3-1.4
Arntl'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
1.3855 × 10-2-1.4
Arntl'Ghrh-KO' vs 'wild type'genotypeGene expression in liver tissue from Ghrh-KO and normal (wild-type) mice
Adjusted p-valueLog2-fold change
2.2145 × 10-21.4
Arntl'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
3.3429 × 10-21.4
Arntl'effluent of advance treatment by quaternized magnetic microsphere' vs 'purified water'environmental stressTranscription profiling by array of M. musculus male liver mice cells to investigate risks in a drinking water plant
Adjusted p-valueLog2-fold change
3.5132 × 10-21.4
Arntl'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Adjusted p-valueLog2-fold change
4.941 × 10-301.3
Arntl'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1'cell type, growth condition, phenotypeTranscription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture
Adjusted p-valueLog2-fold change
1.3891 × 10-15-1.3
Arntl'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.8701 × 10-141.3
Arntl'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
5.0302 × 10-111.3
Arntl'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.2827 × 10-101.3
Arntl'anti-mIL-17F; 500 microgram' vs 'saline' in 'wild type; Mycobacterium tuberculosis H37Rv'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
1.81 × 10-8-1.3
Arntl'6 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
2.8911 × 10-8-1.3
Arntl'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
2.9563 × 10-6-1.3
Arntl'15 degree celsius' vs '20 to 22 degree celsius' in 'Adrb1, Adrb2 and Adrb3 knockout'genotype, temperatureRNA-seq of cold-induced transcriptome changes in subcutaneous adipose tissue of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
3.6771 × 10-6-1.3
Arntl'Reverbαflox/floxAlbCreERT2-' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
1.667 × 10-51.3
Arntl'p19Arf and interferon beta' vs 'eGFP control'genotypeTranscription profiling by microarray of mouse B16F10 cells transduced with cDNAs encoding eGFP control, p19Arf, murine interferon-beta (IF-B) or the combination of p19Arf plus IF-B to study the modulated genes
Adjusted p-valueLog2-fold change
1.9475 × 10-5-1.3
Arntl'collagen sandwich' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.1802 × 10-51.3
Arntl'all-trans-retinoic acid; 5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA Seq of wildtype and Rarb KO HSCs after 24h of in vitro culture and treatment
Adjusted p-valueLog2-fold change
4.8584 × 10-51.3
Arntl'Specific pathogen free' vs 'Germ free'growth conditionThe gut microbiota promotes hepatic fatty acid desaturation and elongation in mice
Adjusted p-valueLog2-fold change
9.1581 × 10-5-1.3
Arntl'acute oropharyngeal candidiasis' vs 'healthy' in wild type micecompound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
9.6504 × 10-51.3
Arntl'Bcl6 -/- BCR-ABL1-transformed B cell precursors; STI571 treated' vs 'Bcl6 -/- BCR-ABL1-transformed B cell precursors; untreated'cell type, treatmentGene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice
Adjusted p-valueLog2-fold change
1.144 × 10-41.3
Arntl'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.6143 × 10-4-1.3
Arntl'Insig1 -/-' vs 'wild type genotype' in 'none; standard diet; acute liver damage'compound, diet, disease, genotypeINSIG1 in NASH pathophysiology and in the hepatic wound-healing response
Adjusted p-valueLog2-fold change
1.6301 × 10-41.3
Arntl'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.8012 × 10-4-1.3
Arntl'isocaloric high-fat diet' vs 'control diet'dietMouse adipose tissue under hypercaloric and isocaloric high-fat diet
Adjusted p-valueLog2-fold change
5.6159 × 10-4-1.3
Arntl"acute exposure to downstream water" vs "acute exposure to control water"environmental history, generationToxicogenomic analysis in liver of mice exposed to polluted groundwater
Adjusted p-valueLog2-fold change
9.7139 × 10-41.3
Arntl'isotype-control; 150 micrograms' vs 'none' in 'methotrexate; first dose 120 milligram per kilogram; second dose 60 milligram per kilogram; wild type phenotype' at '1 day'compound, phenotype, stimulus, timeRNA-seq of mouse crypts to investigate Rorc gamma t-deficient mice tissue repair compared to wild type controls
Adjusted p-valueLog2-fold change
1.0923 × 10-3-1.3
Arntl'db/db' vs 'wild type genotype' in 'control miRNA; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.9814 × 10-3-1.3
Arntl'neoplasm' vs 'normal tissue adjacent to neoplasm'sampling siteTranscription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa
Adjusted p-valueLog2-fold change
8.633 × 10-31.3
Arntl'doxorubicin; 15 milligram per kilogram; wild type' vs 'none; ; wild type'compound, genotypeExpression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5
Adjusted p-valueLog2-fold change
4.9046 × 10-21.3
Arntl'Ms5Yah' vs 'wild type'genotypeTranscription profiling by array of mouse heart from Ts65Dn, Ms5Yah and Ts65DnMs5Yah mouse models
Adjusted p-valueLog2-fold change
1.9151 × 10-35-1.2
Arntl'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
1.0408 × 10-7-1.2
Arntl'5 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
2.5058 × 10-7-1.2
Arntl'7 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
3.0985 × 10-71.2
Arntl'4-oxoretinoic acid; 5 micromolar' vs 'none' in 'Rarb -/-'compound, genotypeRNA Seq of wildtype and Rarb KO HSCs after 24h of in vitro culture and treatment
Adjusted p-valueLog2-fold change
5.4655 × 10-7-1.2
Arntl'4 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.6419 × 10-61.2
Arntl'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.3173 × 10-6-1.2
Arntl'interleukin-3 and stem cell factor' vs 'interleukin-3'growth conditionStem cell factor programs the mast cell activation phenotype
Adjusted p-valueLog2-fold change
3.3221 × 10-61.2
Arntl'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.1599 × 10-4-1.2
Arntl'1810027O10Rik knockout; gonad adipose tissue' vs 'wild type genotype; gonad adipose tissue'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
1.344 × 10-41.2
Arntl'high-fat diet' vs 'isocaloric high-fat diet'dietMouse adipose tissue under hypercaloric and isocaloric high-fat diet
Adjusted p-valueLog2-fold change
1.5013 × 10-41.2
Arntl'trichostatin A and LIF' at '12 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
1.656 × 10-41.2
ArntlSynacthen vs sodium chloride controlcompoundTranscription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses.
Adjusted p-valueLog2-fold change
2.1379 × 10-4-1.2
Arntl'DKO' vs 'wild type'genotypeTranscription profiling by array of wild type and Hdac1 and 2 knockout lymphocytes
Adjusted p-valueLog2-fold change
4.7595 × 10-41.2
Arntl'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.864 × 10-31.2
Arntl'SARS coronavirus MA15' vs 'none' at '1 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
7.8763 × 10-31.2
Arntl'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.1377 × 10-21.2
Arntl'liver; ZT7; sleep restricted' vs 'liver; ZT7; control'organism part, sampling time point, treatmentThe effect of sleep restriction on transcriptome rhythmicity in mice
Adjusted p-valueLog2-fold change
2.5243 × 10-21.2
Arntl'17.5 Gray; X-radiation' vs 'none' at '8 week'irradiate, timeSenescence gene signature of radiation fibrosis
Adjusted p-valueLog2-fold change
3.0928 × 10-2-1.2
Arntl'4 month; diabetes mellitus' vs '4 month; normal'age, diseaseGene expression in OVE26 diabetic kidney during the development of nephropathy
Adjusted p-valueLog2-fold change
3.2146 × 10-2-1.2
Arntl'TRIM28(flox/flox):Mx1Cre' vs 'TRIM28(flox/flox)' in 'CD71(hi)TER119-'genotype, phenotypeTranscription profiling by high throughput sequencing of bone marrow immature erythroid cells from Trim28flox/flox:TgMx1Cre congenic mice
Adjusted p-valueLog2-fold change
3.7645 × 10-2-1.2
Arntl'trinitrobenzene sulfonic acid' vs 'none' in 'Fn14 knockout'compound, genotypeChronic TNBS Colitis in the FN14 KO Mouse
Adjusted p-valueLog2-fold change
2.1127 × 10-34-1.1
Arntl'IL17A homozygous knockout' vs 'wild type genotype' in 'ileum'genotype, organism partRNAseq analysis of colon and ileum tissue from naive wild type, MR1-/- and IL-17A-/- mice
Adjusted p-valueLog2-fold change
5.3815 × 10-241.1
Arntl'nmf205, Gcn2 double mutant' vs 'wild type'genotypeTranscription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/-
Adjusted p-valueLog2-fold change
1.1433 × 10-18-1.1
Arntl'MR1 homozygous knockout' vs 'wild type genotype' in 'ascending colon'genotype, organism partRNAseq analysis of colon and ileum tissue from naive wild type, MR1-/- and IL-17A-/- mice
Adjusted p-valueLog2-fold change
2.254 × 10-15-1.1
Arntl'high GLUT1 expression' vs 'low GLUT1 expression' in 'wild type genotype'genotype, phenotypeRNA-seq analysis of normoxic and hypoxic tumor-associated macrophages from wild type or REDD1 knockout mice
Adjusted p-valueLog2-fold change
1.3398 × 10-71.1
Arntl'anti-CD3/CSA' vs 'anti-CD3' in 'cyclosporine-resistant'phenotype, treatmentActivating CD8 T cell clones via the T cell receptor complex in the absence and presence of cyclosporine A
Adjusted p-valueLog2-fold change
1.9616 × 10-7-1.1
Arntl'cut nerve; 7 day' vs 'none'injury, protocol, timeChanges in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury
Adjusted p-valueLog2-fold change
1.9952 × 10-61.1
Arntl'BCL6 knockout and inducible BACH2 overexpression' vs 'wild type and inducible BACH2 overexpression'genotypeGene expression profile of BCR-ABL1 transformed pre-B mouse cells from BCL6 knockout after inducible overexpression of Bach2
Adjusted p-valueLog2-fold change
7.2824 × 10-61.1
Arntl'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.4775 × 10-41.1
Arntl'phosgene - carbonyl chloride' at '1 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury
Adjusted p-valueLog2-fold change
2.3978 × 10-41.1
Arntl'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
4.0307 × 10-4-1.1
Arntl'myelocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
4.9601 × 10-41.1
Arntl'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
7.9541 × 10-4-1.1
Arntl'colitis' at '19 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
9.7319 × 10-4-1.1
Arntl'acute graft versus host disease' vs 'normal'diseaseTranscription profiling by array of intestinal tissues from mice receiving bone marrow transplantation with or without T-cell stimulation
Adjusted p-valueLog2-fold change
1.0262 × 10-31.1
Arntl'2 week' vs '0 week'timeTranscription profiling by array of mouse colon tissues with T cell transfer-induced colitis at week 0, 2, 4 and 6 post-transfer
Adjusted p-valueLog2-fold change
1.3405 × 10-3-1.1
Arntl'CAR deficient; control' vs 'wild type; control'genotype, treatmentNuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages
Adjusted p-valueLog2-fold change
3.1539 × 10-3-1.1
Arntl'10 microgram; ovalbumin' vs 'none' in 'wild type'compound, genotypeTranscription profiling by array of lungs from mice mutant for RAG after challenge with ovalbumin
Adjusted p-valueLog2-fold change
3.3875 × 10-31.1
Arntl'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
4.683 × 10-31.1
Arntl'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
5.3696 × 10-31.1
Arntl'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
5.5665 × 10-31.1
Arntl'SARS coronavirus MA15 dORF6' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
7.748 × 10-3-1.1
Arntl'sciatic nerves at the midtight level crushed by compression' vs 'none' in 'wild type; gastrocnemius'clinical treatment, genotype, organism partGene expression profiling of muscles from transgenic humanSODG93A mice at symptomatic stage
Adjusted p-valueLog2-fold change
9.0063 × 10-3-1.1
Arntl'UO126; 0.2 milligram per kilogram; miR-1-133a_dKO' vs 'miR-1-133a_FGFR1_tKO'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
1.0588 × 10-2-1.1
Arntl'chronic DSS-induced colitis; 3x DSS, recovery' vs 'none; none'clinical treatment, diseaseTranscription profiling by array of colon tissues isolated from mice with acute and chronic dextran sodium sulphate (DSS)-induced colitis
Adjusted p-valueLog2-fold change
1.1144 × 10-2-1.1
Arntl'1.0% quercetin diet' vs 'control'dietHepatic gene expression in BALB/c mice fed a quercetin diet
Adjusted p-valueLog2-fold change
1.194 × 10-21.1
Arntl'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
1.2218 × 10-21.1
Arntl'Fhl1 knockdown by siRNA' vs 'wild type' at '3 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
1.7206 × 10-21.1
Arntl'normal skin; PKC alpha-/-' vs 'normal skin; wild type genotype'clinical history, genotypeAltered dermal architecture in PKCα-/- skin
Adjusted p-valueLog2-fold change
2.275 × 10-2-1.1
Arntl'Tfc knockout; normal' vs 'control'disease, genotypeGene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor.
Adjusted p-valueLog2-fold change
2.4595 × 10-21.1
Arntl'upf3 knockout' vs 'wild type' in 'testis'cell type, genotypeUPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs
Adjusted p-valueLog2-fold change
2.5072 × 10-21.1
Arntl'Mdr2-knockout' vs 'wild type'genotypeGene Expression Data for female C57BL/6, Mdr2-KO and Mdr2-KO/IL6-KO at the age of 14 months
Adjusted p-valueLog2-fold change
3.1276 × 10-21.1
Arntl'S6K1 knockout' vs 'wild type' in 'white adipose tissue'genotype, organism partTranscription profiling of mouse long-lived S6K1 -/- strain females compared to wild types
Adjusted p-valueLog2-fold change
3.3267 × 10-21.1
Arntl'Plasmodium chabaudi infection' vs 'no infection' in 'vaccination'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
2.2345 × 10-291
Arntl'4-hydroxytamoxifen-mediated deletion of Prmt5' vs 'wild type' in 'mouse neural progenitor cell'cell type, phenotypeTranscription profiling by high throughput sequencing of murine neural stem/progenitor cells lacking PRMT5 over control
Adjusted p-valueLog2-fold change
6.0697 × 10-201
Arntl"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "PWK/PhJ"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
2.1388 × 10-171
Arntl'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.9927 × 10-13-1
Arntl'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
3.9474 × 10-12-1
Arntl'high GLUT1 expression' vs 'low GLUT1 expression' in 'Ddit4 knockout'genotype, phenotypeRNA-seq analysis of normoxic and hypoxic tumor-associated macrophages from wild type or REDD1 knockout mice
Adjusted p-valueLog2-fold change
8.5677 × 10-101
Arntl'ReverbαFlox2-6AdipoCre+' vs 'ReverbαFlox2-6AdipoCre-' in 'high fat diet; 28 week'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
1.0724 × 10-7-1
Arntl'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
1.2946 × 10-7-1
Arntl'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.5579 × 10-71
Arntl'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.7856 × 10-6-1
Arntl'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
6.5082 × 10-61
Arntl'phosgene - carbonyl chloride' at '0.5 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury
Adjusted p-valueLog2-fold change
8.8123 × 10-61
Arntl'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
1.02 × 10-51
Arntl'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
2.2045 × 10-51
Arntl'10 month' vs '2 month'ageRNA-seq of adipocyte progenitor cells derived from old and young mice to investigate the molecular signature of aging
Adjusted p-valueLog2-fold change
8.9924 × 10-5-1
Arntl'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.9465 × 10-51
Arntl'nutlin-3a; polarized with interleukin 4 and interleukin 13.' vs 'untreated'compound, treatmentExpression data from polarized macrophages: effect of p53
Adjusted p-valueLog2-fold change
1.3841 × 10-4-1
Arntl'oral hard palate epithelium' vs 'tail skin epithelium'organism partTranscriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression
Adjusted p-valueLog2-fold change
3.9991 × 10-41
Arntl'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 2 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
6.2206 × 10-41
Arntl'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype'genotypeTranscription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy
Adjusted p-valueLog2-fold change
1.0497 × 10-3-1
Arntl'2'-fucosyllactose supplementation' vs 'control' in '8 weeks post-ileocecal resection'diet, treatmentTranscriptomic characterization of the impact of 2'-fucosyllactose supplementation on intestinal adaptation following ileocecal resection.
Adjusted p-valueLog2-fold change
1.101 × 10-31
Arntl'cycloheximide and 100 unit per milliliter interferon alpha' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
1.1634 × 10-3-1
Arntl'Rb;E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.3996 × 10-3-1
Arntl'c-Myc activation' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
1.86 × 10-31
Arntl'cycloheximide' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
4.2645 × 10-31
Arntl'Mdr2-knockout/IL-6-knockout' vs 'wild type'genotypeGene Expression Data for female C57BL/6, Mdr2-KO and Mdr2-KO/IL6-KO at the age of 14 months
Adjusted p-valueLog2-fold change
4.5724 × 10-3-1
Arntl'Kaiso knockout' vs 'wild type phenotype'phenotypeGene expression microarray analysis of whole intestine from Kaiso-/- mice
Adjusted p-valueLog2-fold change
5.3641 × 10-31
Arntl'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
5.5561 × 10-3-1
Arntl'2 day' vs '0 day'timeTranscription profiling by array of mouse colon tissues under dextran sodium sulphate induction for 2, 4 and 6 days against uninduced controls at day 0
Adjusted p-valueLog2-fold change
7.0882 × 10-31
Arntl'Stella maternal / zygotic knockout' vs 'wild type genotype' in '2-cell embryo'developmental stage, genotypeTranscription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development
Adjusted p-valueLog2-fold change
7.1977 × 10-31
Arntl'tamoxifen; autosomal dominant polycystic kidney disease' vs 'none; normal'compound, disease, timeExpression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC
Adjusted p-valueLog2-fold change
8.194 × 10-3-1
Arntl'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
1.011 × 10-2-1
Arntl'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
2.0024 × 10-2-1
Arntl'dextran sodium sulphate induced colitis' vs 'normal' in 'water'compound, diseaseTranscription profiling by array of murine colon tissue after exposure to 4% dextran sodium sulphate (DSS) for 6 days followed by 4 days of water or 1% L-arginine to study the effect of L-arginine on DSS-induced colitis
Adjusted p-valueLog2-fold change
2.3278 × 10-2-1
Arntl'AUY922; 100 nanomolar' vs 'DMSO; 0.1 percent' in 'Mll1 knockout'compound, genotypeIdentification of targets regulated by MLL1 in response to HSP90 inhibitors
Adjusted p-valueLog2-fold change
2.4888 × 10-21
Arntl'S6K1 knockout' vs 'wild type' in 'muscle'genotype, organism partTranscription profiling of mouse long-lived S6K1 -/- strain females compared to wild types
Adjusted p-valueLog2-fold change
2.7762 × 10-21
Arntl'essential fatty acid deficient' vs 'control'dietLiver mRNA microarray study for mice treated with various diets
Adjusted p-valueLog2-fold change
2.8842 × 10-21
Arntl'Tyr mutant' vs 'wild type'genotypeMicroarray analysis of iris gene expression in mice with mutations relevant to glaucoma
Adjusted p-valueLog2-fold change
3.2066 × 10-2-1
Arntl'fear conditioning' vs 'none'stimulusGene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage
Adjusted p-valueLog2-fold change
3.7819 × 10-2-1
Arntl'injected with sperm-derived RNA fragments from mice subjected to early life stress (MSUS)' vs 'injected with sperm-derived RNA fragments from control non-stressed mice'stimulusZygotic expression after parental early life stress
Adjusted p-valueLog2-fold change
3.8112 × 10-21
Arntl'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Synonym
MOP3, Arnt3, bHLHe5, Bmal1
Ortholog
ARNTL (Pongo abelii), ARNTL (Bos taurus), ARNTL (Gallus gallus), ARNTL (Chlorocebus sabaeus), ARNTL (Oryctolagus cuniculus), ARNTL (Anas platyrhynchos), ARNTL (Monodelphis domestica), ENSACAG00000004497 (Anolis carolinensis), arntl1a (Tetraodon nigroviridis), ARNTL (Dasypus novemcinctus), gce (Drosophila melanogaster), ENSPANG00000006538 (Papio anubis), Arntl (Rattus norvegicus), ARNTL (Ornithorhynchus anatinus), tgo (Drosophila melanogaster), arntl1b (Danio rerio), ARNTL (Equus caballus), aha-1 (Caenorhabditis elegans), arnt (Ciona intestinalis), Met (Drosophila melanogaster), ARNTL (Sus scrofa), ARNTL (Homo sapiens), ARNTL (Gorilla gorilla), ENSOARG00020009923 (Ciona intestinalis), arntl1a (Danio rerio), ENSCSAVG00000010893 (Ciona savignyi), ARNTL (Macaca mulatta), ARNTL (Pan troglodytes), arntl (Xenopus tropicalis)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4906121, 5364937, 10556463, 5554527, 4631181, 102382_at, 10556487, 5609981, 4815927, 5605085, 5512153, 4836326, 4409913, 4606144, 5206800, 4792046, 4945569, ILMN_2707510, 5433766, ILMN_1243097, 5389226, 4521477, A_52_P267651, A_52_P24690, 4843426, 4765697, 4498899, 1425099_a_at, 1438862_at, 5183038, A_55_P2408588, 5141371, 5602506, 17481960, 4827908, 4863629, 4444790, 4787921, 4715617, 5535707, 4729198