ENSMUSG00000055609 (Hba-x)

mus musculus

hemoglobin X, alpha-like embryonic chain in Hba complex

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Mus musculus
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Showing 2 experiments:
Created with Highcharts 6.2.0adult CCAP neuronalpha’/beta’ middle Kenyon cellcentrifugal neuron C3distal medullary amacrine neuron Dm10distal medullary amacrine neuron Dm9dopaminergic PAM neuron 6gamma dorsal Kenyon celllamina monopolar neuron L2lobula columnar neuron LC10alobula columnar neuron LC6lobula-lobula plate columnar neuron LLPC1mushroom body output neuronproximal medullary amacrine neuron Pm3transmedullary neuron Tm1transmedullary neuron Tm4adult lamina marginal glial cellalpha/beta posterior Kenyon cellcolumnar neuron T1distal medullary amacrine neuron Dm3dopaminergic PAM neuron 3dopaminergic PAM neuron 9lamina intrinsic neuronlamina monopolar neuron L5lobula columnar neuron LC10dlobula plate tangential neuronmedullary intrinsic neuron Mi4photoreceptor cell R7T neurontransmedullary neuron Tm29
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Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.8356 × 10-9-10
Hba-x'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
5.0757 × 10-139.5
Hba-x'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.3643 × 10-6-9.4
Hba-x'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.7003 × 10-6-8.6
Hba-x'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
8.4355 × 10-5-8.2
Hba-x'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.3363 × 10-158
Hba-x'6 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
5.381 × 10-138
Hba-x'7 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
6.0111 × 10-78
Hba-x'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.2016 × 10-11-7.7
Hba-x'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
2.2062 × 10-106.9
Hba-x'5 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
4.1206 × 10-136.7
Hba-x'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.7405 × 10-75.7
Hba-x'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.7643 × 10-13-5.1
Hba-x'embryonic day 16.5' vs 'embryonic day 11.5'developmental stageGene expression profile of diaphragm morphogenesis at different developmental stages
Adjusted p-valueLog2-fold change
5.2412 × 10-64.5
Hba-x'168 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
6.7256 × 10-13-4.1
Hba-x'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
1.2574 × 10-5-4
Hba-x'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.7083 × 10-43.8
Hba-x'Ckit negative' vs 'Ckit positive'cell typeGene expression profile of c-kit positive and c-kit negative cells
Adjusted p-valueLog2-fold change
2.8874 × 10-103.7
Hba-x'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
5.7205 × 10-4-3.4
Hba-x'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
7.0514 × 10-4-3.2
Hba-x'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
6.3326 × 10-52.9
Hba-x'erythroblast' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
3.311 × 10-7-2.8
Hba-x'LDB1 knock-down' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
1.0406 × 10-4-2.8
Hba-x'megakaryocyte' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
6.6048 × 10-3-2.8
Hba-x'CD2314 and BIO' vs 'none' at '6 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
7.1066 × 10-112.6
Hba-x'16 day' vs '0 day'ageGene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26)
Adjusted p-valueLog2-fold change
5.4156 × 10-5-2.6
Hba-x'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
4.1529 × 10-52.4
Hba-x'Men1-null' vs 'wild type'genotypeDifferentially regulated genes in adipocytes derived from Men1-null vs WT mouse embryonic stem cells
Adjusted p-valueLog2-fold change
4.0573 × 10-152.1
Hba-x'sorafenib treatment' vs 'DMSO control' in 'Ba/F3-ITD cells'compoundTranscription profiling by array of murine Ba/F3-ITD cells treated with DMSO or sorafenib
Adjusted p-valueLog2-fold change
3.7326 × 10-31.7
Hba-x'BAHD1 knockout' vs 'wild type' in 'liver'genotype, organism partTranscriptome expression profile of embryonic liver and placenta tissue from BAHD1+/+ (WT) and BAHD1-/- (KO) mice at embryonic day E16.5
Adjusted p-valueLog2-fold change
1.8313 × 10-2-1.7
Hba-x'Tbx5;Nkx2-5 knockout' vs 'wild type'genotypeTranscription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse
Adjusted p-valueLog2-fold change
2.9101 × 10-71.6
Hba-x'Runx1 knockdown; none' vs 'wild type; none'genotype, stimulusTranscription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor
Adjusted p-valueLog2-fold change
1.6126 × 10-51.5
Hba-x'Tdp2Delta1-3' vs 'wild type'genotypeExpression data from E16.5 mouse embryonic brain wild-type and knock-out conditions
Adjusted p-valueLog2-fold change
7.017 × 10-4-1.5
Hba-x'LDB1 knock-down with full-length Ldb1 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
2.4997 × 10-31.5
Hba-x'homozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5'developmental stage, genotypeMicroarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels
Adjusted p-valueLog2-fold change
8.8497 × 10-31.5
Hba-x'CD2314 and BIO' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
7.9884 × 10-61.4
Hba-x'estradiol' at '30 hour' vs 'none' at '0 hour'compound, timeTranscription profiling by array of G1E cells during time course treatment with estradiol.
Adjusted p-valueLog2-fold change
7.6263 × 10-31.3
Hba-x'BIO' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
3.9098 × 10-21.3
Hba-x'Tmod3 knockout; small fetal liver, anemia' vs 'control; normal'genotype, phenotypeTmod3-/- mouse fetal liver compared with wild type
Adjusted p-valueLog2-fold change
5.2727 × 10-4-1.2
Hba-x'acute graft vs. host disease' vs 'normal'compound, diseaseTranscription profiling by array of murine thymus medulla in the absence and presence of acute graft-versus-host disease
Adjusted p-valueLog2-fold change
3.0044 × 10-41.1
Hba-x'Runx1 knockdown; induce erythroid differentiation' vs 'wild type; induce erythroid differentiation'genotype, stimulusTranscription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor
Adjusted p-valueLog2-fold change
4.638 × 10-3-1.1
Hba-x'FLT3-ITD Y842F mutant' vs 'FLT3-ITD'genotypeTyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD
Adjusted p-valueLog2-fold change
1.1945 × 10-41
Hba-x'6 day' vs '0 day'ageGene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26)
Adjusted p-valueLog2-fold change
9.6014 × 10-41
Hba-x'Klf3-/-' vs 'wild type'genotypeRNA-Seq analysis of KLF3 knockout E14.5 TER119+ (erythroid) murine fetal liver cells
Adjusted p-valueLog2-fold change
1.392 × 10-31
Hba-x'heterozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5'developmental stage, genotypeMicroarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels
Adjusted p-valueLog2-fold change
4.5373 × 10-3-1
Hba-x'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
4.9725 × 10-3-1
Hba-x'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
7.7214 × 10-3-1
Hba-x'7 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Synonym
zeta globin
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
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UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
Msa.703.0_f_at, 4337687, m26898_f_at, 4829544, 4464442, 5558271, 5578129, 1448716_at, 10375046, 100549_at, 4318946, A_51_P204053, 17248255, ILMN_1240267