ENSMUSG00000056025 (Clca3a1)

mus musculus

chloride channel accessory 3A1

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Experimental variables
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.5359 × 10-23-8.2
Clca3a1'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
3.4735 × 10-10-7.1
Clca3a1'Lin- Dapi-EpCAM- CD31+td-tomato+' vs 'Lin- Dapi-EpCAM- CD31+td-tomato-' in 'vascular endothelial cell'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
1.9021 × 10-6-6.5
Clca3a1'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
7.9474 × 10-6-5
Clca3a1'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.929 × 10-1464.9
Clca3a1'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.935 × 10-3-4.7
Clca3a1'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
1.6368 × 10-3-4.6
Clca3a1'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.0333 × 10-54.5
Clca3a1'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.0537 × 10-114.2
Clca3a1'wild type; SARS MA15; 2 day' vs 'wild type; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
1.6948 × 10-94.2
Clca3a1'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
1.3938 × 10-94.1
Clca3a1'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
1.8069 × 10-74.1
Clca3a1'SARS coronavirus MA15 dORF6' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
9.1197 × 10-74.1
Clca3a1'SARS coronavirus MA15' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
2.9866 × 10-54.1
Clca3a1'p48-Cre;KrasG12D;Ela-Tgfa' vs 'wild type'genotypeTranscription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice
Adjusted p-valueLog2-fold change
3.0698 × 10-74
Clca3a1'ko cyld-/-' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Cyld inactivation
Adjusted p-valueLog2-fold change
5.4669 × 10-6-4
Clca3a1'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
6.6065 × 10-93.9
Clca3a1'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
1.1234 × 10-73.9
Clca3a1'SARS coronavirus MA15' vs 'none' at '2 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
3.1133 × 10-463.8
Clca3a1'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.2028 × 10-223.8
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.0386 × 10-103.8
Clca3a1'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
7.7862 × 10-93.8
Clca3a1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
6.5924 × 10-63.8
Clca3a1'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
7.0536 × 10-4-3.8
Clca3a1'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.0087 × 10-21-3.7
Clca3a1'interferon gamma' vs 'dexamethasone; 100 nanomolar'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
2.6071 × 10-93.6
Clca3a1'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
1.3872 × 10-63.6
Clca3a1'Ela-Tgfa' vs 'wild type'genotypeTranscription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice
Adjusted p-valueLog2-fold change
6.0348 × 10-43.6
Clca3a1'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
5.4368 × 10-63.4
Clca3a1'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
3.8921 × 10-43.4
Clca3a1'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
6.9084 × 10-4-3.4
Clca3a1'total RNA; HRasV12 and c-Myc overexpression and Eif4e heterozygous knockout' vs 'total RNA; wild type'fraction, genotypeRedefining the role of eIF4E dose in development, cancer, and protein synthesis
Adjusted p-valueLog2-fold change
3.1693 × 10-233.3
Clca3a1'10 Gy Gray; x-ray' vs 'none' in 'tumor and stromal cell'cell type, irradiateRNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated
Adjusted p-valueLog2-fold change
1.2297 × 10-83.2
Clca3a1'chronic pancreatitis' vs 'control'diseasePancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
Adjusted p-valueLog2-fold change
1.5441 × 10-23.2
Clca3a1'Alb-Cre;VHLf/f' vs 'Alb-Cre'genotypeTranscription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor
Adjusted p-valueLog2-fold change
3.5792 × 10-513.1
Clca3a1'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
8.1614 × 10-83.1
Clca3a1'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
2.9226 × 10-63.1
Clca3a1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
3.7102 × 10-43.1
Clca3a1'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
8.8847 × 10-33.1
Clca3a1'miR-34a overexpression' vs 'control'phenotypeTranscriptional profiling of lung cancer cells over-expression miR-34a.
Adjusted p-valueLog2-fold change
4.3053 × 10-753
Clca3a1'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
3.1542 × 10-133
Clca3a1'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.5385 × 10-53
Clca3a1'3 day' vs '1 day' in 'influenza A infected DBA/2J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
2.4873 × 10-53
Clca3a1'chemical hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo.
Adjusted p-valueLog2-fold change
1.2762 × 10-43
Clca3a1'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
5.4377 × 10-43
Clca3a1'SARS coronavirus MA15' vs 'none' at '7 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
1.1934 × 10-82.9
Clca3a1'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
1.3274 × 10-52.9
Clca3a1'SARS coronavirus MA15' vs 'none' at '4 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
1.7845 × 10-42.9
Clca3a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
6.3201 × 10-42.9
Clca3a1'unilateral ureteral obstruction' vs 'sham' in 'wild type'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
1.2767 × 10-32.9
Clca3a1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.8994 × 10-2-2.9
Clca3a1'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
4.4656 × 10-212.8
Clca3a1'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.2017 × 10-62.8
Clca3a1'Foxd3 knockout' vs 'control'phenotypeExpression data from embryonic stem cells differentiation
Adjusted p-valueLog2-fold change
2.0991 × 10-2-2.8
Clca3a1'19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
1.6912 × 10-192.7
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.4058 × 10-172.7
Clca3a1'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.247 × 10-72.7
Clca3a1'chronic cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
1.0763 × 10-52.7
Clca3a1'LDB1 knock-down' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
9.7985 × 10-42.7
Clca3a1'liver specific SMARCB1 knockout' vs 'wild type'phenotypeTP53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors
Adjusted p-valueLog2-fold change
1.8468 × 10-22.7
Clca3a1'extensive self renewing erythroblast' vs 'restrictive self renewing erythroblast'cell typeRestrictive and extensively self-renewing erythroblast
Adjusted p-valueLog2-fold change
2.5805 × 10-22.7
Clca3a1'3D culture' vs '2D culture'growth conditionmRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture
Adjusted p-valueLog2-fold change
6.4072 × 10-512.6
Clca3a1'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
9.2926 × 10-332.6
Clca3a1'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
2.3535 × 10-122.6
Clca3a1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'biliary-derived proliferative ducts (bilDP)'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
1.0617 × 10-32.6
Clca3a1'PAI1 knockout; SARS MA15; 7 day' vs 'PAI1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
3.4119 × 10-32.6
Clca3a1'SARS coronavirus MA15' vs 'none' at '4 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
3.1591 × 10-22.6
Clca3a1'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '7 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.6436 × 10-322.5
Clca3a1'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
1.3109 × 10-52.5
Clca3a1'4 day' vs '1 day' in 'influenza A infected DBA/2J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
2.1094 × 10-22.5
Clca3a1'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '4 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
3.1472 × 10-72.4
Clca3a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
5.2767 × 10-72.4
Clca3a1'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
1.1395 × 10-52.4
Clca3a1'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.3727 × 10-52.4
Clca3a1'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.3923 × 10-5-2.4
Clca3a1'tristetrapolin knockout' vs 'wild type' in 'none' at '0 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
5.2548 × 10-5-2.4
Clca3a1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '30 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
5.4738 × 10-5-2.4
Clca3a1'carotid body' vs 'adrenal medulla'organism partExpression profile of mouse carotid body and adrenal medulla [RNA-Seq]
Adjusted p-valueLog2-fold change
1.6193 × 10-32.4
Clca3a1'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
3.4343 × 10-2-2.4
Clca3a1'total RNA; HRasV12 and c-Myc overexpression and Eif4e wild type' vs 'total RNA; wild type'fraction, genotypeRedefining the role of eIF4E dose in development, cancer, and protein synthesis
Adjusted p-valueLog2-fold change
1.1151 × 10-172.3
Clca3a1'dexamethasone; 100 nanomolar' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
4.725 × 10-10-2.3
Clca3a1'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.6927 × 10-7-2.3
Clca3a1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.4149 × 10-5-2.3
Clca3a1'oral hard palate epithelium' vs 'tail skin epithelium'organism partTranscriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression
Adjusted p-valueLog2-fold change
2.1394 × 10-5-2.3
Clca3a1'renin-expression' vs 'control'phenotypeExpression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein.
Adjusted p-valueLog2-fold change
2.4506 × 10-42.3
Clca3a1'TIMP1 knockout; SARS MA15; 4 day' vs 'TIMP1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
4.7276 × 10-4-2.3
Clca3a1'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
8.7154 × 10-42.3
Clca3a1'STAT1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '9 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
2.4896 × 10-32.3
Clca3a1'Alb-Cre;HIF1dPA/HIF2dPA' vs 'Alb-Cre'genotypeTranscription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor
Adjusted p-valueLog2-fold change
7.036 × 10-32.3
Clca3a1'CD2AP-/-' vs 'wild type genotype' in 'renal glomerular mesangial cell'cell type, genotypeTranscription profiling by array of three major cell types of the glomerulus (podocytes, mesangial cells and endothelial cells) from CD2AP-/- mutant mice and normal controls
Adjusted p-valueLog2-fold change
1.0387 × 10-92.2
Clca3a1'dexamethasone; 100 nanomolar; interferon gamma' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
1.1328 × 10-7-2.2
Clca3a1'Nippostrongylus brasiliensis' vs 'none'infectRNAseq of small intestinal epithelium extracted from mice infected with Nippostrongylus brasiliensis
Adjusted p-valueLog2-fold change
1.1926 × 10-72.2
Clca3a1'methionine- and choline-deficient, high fat diet' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
1.5242 × 10-72.2
Clca3a1'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
1.0725 × 10-52.2
Clca3a1'14 days P. chabaudi infected' vs 'uninfected' in 'intact male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
5.7664 × 10-52.2
Clca3a1'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, and PLAT knock-out mice
Adjusted p-valueLog2-fold change
1.6266 × 10-32.2
Clca3a1'2 day' vs '1 day' in 'influenza A infected DBA/2J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
1.3406 × 10-282.1
Clca3a1'RBM20 antisense oligonucleotide' vs 'none' in 'wild type genotype'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
1.9817 × 10-192.1
Clca3a1'poly(I:C)' vs 'none'stimulus3’-Seq of ex vivo isolated mouse multipotent steady state hematopoietic stem cells (sHSC) and proliferating HSCs
Adjusted p-valueLog2-fold change
2.2866 × 10-142.1
Clca3a1'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
6.9316 × 10-92.1
Clca3a1'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
9.7249 × 10-82.1
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.6002 × 10-72.1
Clca3a1'wild type genotype; SARS MA15; 7 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
5.8598 × 10-6-2.1
Clca3a1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
3.0837 × 10-52.1
Clca3a1'ductus arteriosis' vs 'aorta'organism partGene Profiling in Mouse Fetal Ductus Arteriosus
Adjusted p-valueLog2-fold change
5.595 × 10-52.1
Clca3a1'PAI1 knockout; SARS MA15; 4 day' vs 'PAI1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
1.1884 × 10-4-2.1
Clca3a1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
2.0855 × 10-32.1
Clca3a1'17.5 Gray; X-radiation' vs 'none' at '4 week'irradiate, timeSenescence gene signature of radiation fibrosis
Adjusted p-valueLog2-fold change
3.2133 × 10-32.1
Clca3a1'Mycobacterium tuberculosis; DBA/2J congenic; 30 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
7.2827 × 10-32.1
Clca3a1'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
4.4853 × 10-152
Clca3a1'Pkhd1Cre; Pkd2 F/F; miR-21null' vs 'wild type'genotypeNext Generation Sequencing of PKD2 mutant mice kidneys
Adjusted p-valueLog2-fold change
1.2412 × 10-122
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.1679 × 10-8-2
Clca3a1'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.4506 × 10-62
Clca3a1'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
8.1947 × 10-62
Clca3a1'14 days P. chabaudi infected' vs 'uninfected' in 'intact female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
4.3592 × 10-5-2
Clca3a1'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.6746 × 10-42
Clca3a1'West Nile virus; late stage encephalitis' vs 'early stage encephalitis'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
4.1103 × 10-4-2
Clca3a1'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
1.7422 × 10-3-2
Clca3a1'15 day' vs '0 day'ageTime course analysis of the cardiac transcriptome in the neonatal period
Adjusted p-valueLog2-fold change
2.5518 × 10-32
Clca3a1'SARS coronavirus MA15 dORF6' vs 'none' at '4 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
3.8288 × 10-32
Clca3a1'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '4 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
5.3814 × 10-32
Clca3a1'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '12 month'age, genotypeErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression]
Adjusted p-valueLog2-fold change
6.5625 × 10-3-2
Clca3a1'SARS coronavirus MA15 nsp16 -/-' vs 'SARS coronavirus MA15' at '7 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
1.6307 × 10-22
Clca3a1'Alb-Cre;HIF2dPA' vs 'Alb-Cre'genotypeTranscription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor
Adjusted p-valueLog2-fold change
2.7573 × 10-191.9
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.8406 × 10-141.9
Clca3a1'Pkhd1Cre; Pkd2 F/F' vs 'wild type'genotypeNext Generation Sequencing of PKD2 mutant mice kidneys
Adjusted p-valueLog2-fold change
3.0071 × 10-131.9
Clca3a1'Col1a1-tetO-MLL/ENL' vs 'wild type' in 'hematopoietic stem cell'cell type, genotypeTranscription profiling by high throughput sequencing of hematopoietic stem cells from a conditional-inducible mouse model of the MLL-ENL fusion oncogene
Adjusted p-valueLog2-fold change
3.0482 × 10-91.9
Clca3a1'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
6.4858 × 10-81.9
Clca3a1'CD36 knockout' vs 'wild type genotype' in 'oxidized low density lipoprotein; 25 microgram per milliliter'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
1.8657 × 10-71.9
Clca3a1'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
8.0306 × 10-7-1.9
Clca3a1'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
4.1373 × 10-51.9
Clca3a1'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
7.0319 × 10-51.9
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.4846 × 10-41.9
Clca3a1'resiquimod; 100 microgram' vs 'none' in 'ovalbumin; A/J'compound, stimulus, strainTranscription profiling of mouse model of asthma reveals the effects of resiquimod treatment on the asthma transcriptome
Adjusted p-valueLog2-fold change
3.1255 × 10-41.9
Clca3a1'SARS coronavirus MA15' vs 'none' in 'STAT1 -/-' at '5 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
1.5953 × 10-31.9
Clca3a1'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
6.4434 × 10-3-1.9
Clca3a1'IEC-specific HDAC3 deletion' vs 'floxed HDAC3 (wild type)'genotypeTranscription profiling by array of intestinal epithelial cells (IECs) from mice with IEC-specific HDAC3 deletion against wild type controls
Adjusted p-valueLog2-fold change
7.8352 × 10-31.9
Clca3a1'Cbs knockout' vs 'wild type'genotypeGene expression profile of CD4-positive T cells from mouse Cbs knockout
Adjusted p-valueLog2-fold change
9.0481 × 10-31.9
Clca3a1'Fancc-/-' vs 'wild type'genotypeTranscription profiling by array of bone marrow cells from wild type, Fancc-deficient, Fancg-deficient, and doubly deficient (Fancc/Fancg) mice
Adjusted p-valueLog2-fold change
1.0272 × 10-21.9
Clca3a1'infarct and border region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
3.7419 × 10-21.9
Clca3a1'130 week' vs '13 week' in 'kidney'age, organism partTranscription profiling by array of liver, lung, spleen and kidney from young and old mice.
Adjusted p-valueLog2-fold change
4.2195 × 10-21.9
Clca3a1'K-ras mutant/Wt1-null' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
4.8151 × 10-21.9
Clca3a1'K-ras mutant' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
4.8437 × 10-21.9
Clca3a1'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
1.0236 × 10-121.8
Clca3a1'interleukin-28A; 1000 nanogram per milliliter' vs 'none'compoundTranscription profiling by high throughput sequencing of murine small intestinal epithelial cells stimulated with interleukin-28A
Adjusted p-valueLog2-fold change
4.6165 × 10-81.8
Clca3a1'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
2.5239 × 10-7-1.8
Clca3a1'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.6968 × 10-7-1.8
Clca3a1'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
7.8555 × 10-7-1.8
Clca3a1'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
5.467 × 10-61.8
Clca3a1'West Nile virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
2.1673 × 10-51.8
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.0667 × 10-51.8
Clca3a1'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
3.7316 × 10-41.8
Clca3a1'colitis' at '19 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
9.6911 × 10-41.8
Clca3a1'Pten knockout' vs 'wild type' at '15 month'genotype, timeTranscription profiling by array of Pten knockout liver cells of mouse
Adjusted p-valueLog2-fold change
1.8245 × 10-31.8
Clca3a1'liver-specific Gp130 knockout mice [Gp130delta(hepa)]; cecal ligation and puncture' vs 'liver-specific Gp130 knockout mice [Gp130delta(hepa)]; control'genotype, treatmentHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Adjusted p-valueLog2-fold change
2.0097 × 10-31.8
Clca3a1'db/db' vs 'wild type genotype' in 'control miRNA; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.9819 × 10-31.8
Clca3a1'TIMP1 knockout; SARS MA15; 7 day' vs 'TIMP1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
3.2796 × 10-31.8
Clca3a1'CD2AP-/-' vs 'wild type genotype' in 'renal glomerular endothelial cell'cell type, genotypeTranscription profiling by array of three major cell types of the glomerulus (podocytes, mesangial cells and endothelial cells) from CD2AP-/- mutant mice and normal controls
Adjusted p-valueLog2-fold change
5.7366 × 10-31.8
Clca3a1'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
1.5766 × 10-29-1.7
Clca3a1'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
7.1682 × 10-26-1.7
Clca3a1'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
1.2969 × 10-71.7
Clca3a1'7 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
1.7217 × 10-71.7
Clca3a1'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.7313 × 10-6-1.7
Clca3a1'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
3.4804 × 10-61.7
Clca3a1'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.3689 × 10-61.7
Clca3a1'methionine- and choline-deficient, high fat diet mixed with 0.1% metformin' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
4.8933 × 10-51.7
Clca3a1'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
7.0169 × 10-51.7
Clca3a1'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
9.5742 × 10-41.7
Clca3a1'12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
2.2224 × 10-31.7
Clca3a1'Mettl6 knockout clone D1' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
2.6775 × 10-3-1.7
Clca3a1'Rb1 mutant' vs 'wild type'genotypeA retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene targeted mice
Adjusted p-valueLog2-fold change
5.5019 × 10-31.7
Clca3a1'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
8.0793 × 10-31.7
Clca3a1'24 month' vs '3 month' in 'wild type genotype'age, genotypeRNA from young and aged mouse hematopoietic stem cells
Adjusted p-valueLog2-fold change
1.7116 × 10-21.7
Clca3a1'miR-155 overexpression' vs 'wild type genotype'genotypeExpression analysis of eu-miR-155 transgenic mice B-cells.
Adjusted p-valueLog2-fold change
3.0552 × 10-21.7
Clca3a1'Nr4a1 Nr4a3 double knockout' vs 'wild type genotype'genotypeExpression data of mouse hematopoietic cells, Nr4a1/3 wild type and double mutant
Adjusted p-valueLog2-fold change
3.3447 × 10-2-1.7
Clca3a1'colitis' vs 'normal' in 'wild type'compound, disease, genotypeTranscription profiling by array of wild-type or Thrombospondin 1 (TSP-1) null mouse dextran sulphate sodium (DSS)-induced colitis treated with various forms of TSP-1, a protein with regulatory functions in inflammation and cancer
Adjusted p-valueLog2-fold change
8.1198 × 10-81.6
Clca3a1'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
8.1929 × 10-71.6
Clca3a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.3569 × 10-41.6
Clca3a1'db/db' vs 'wild type genotype' in 'Gabpa miRNA; fasted'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.7799 × 10-41.6
Clca3a1'resiquimod; 100 microgram' vs 'none' in 'ovalbumin; C57BL/6'compound, stimulus, strainTranscription profiling of mouse model of asthma reveals the effects of resiquimod treatment on the asthma transcriptome
Adjusted p-valueLog2-fold change
9.0298 × 10-41.6
Clca3a1'cut nerve; 7 day' vs 'none'injury, protocol, timeChanges in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury
Adjusted p-valueLog2-fold change
1.7605 × 10-31.6
Clca3a1'transgenic hepatic growth hormone and hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
2.0095 × 10-31.6
Clca3a1'9 day' vs '0 day'timeTranscription profiling by array of mineralising murine vascular smooth muscle cell cultures over a nine day culture period to identify new regulators of vascular mineralization
Adjusted p-valueLog2-fold change
2.4257 × 10-31.6
Clca3a1'Lkb1 -/- Pten-/-' vs 'wild type'genotypeLoss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells
Adjusted p-valueLog2-fold change
2.8943 × 10-31.6
Clca3a1'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
3.5218 × 10-31.6
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.0039 × 10-3-1.6
Clca3a1'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
1.3216 × 10-21.6
Clca3a1'doxorubicin; 15 milligram per kilogram; wild type' vs 'none; ; wild type'compound, genotypeExpression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5
Adjusted p-valueLog2-fold change
2.6756 × 10-21.6
Clca3a1'megakaryocyte' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
2.8996 × 10-2-1.6
Clca3a1'Ngn3-expressing cell' vs 'Ngn3-null cell'cell typeTranscriptional profiling of Ngn3-dependent pancreatic endocrine differentiation at E15.5
Adjusted p-valueLog2-fold change
3.6702 × 10-21.6
Clca3a1'PLAT knockout; SARS MA15; 7 day' vs 'PLAT knockout; mock'genotype, infect, timeSARS infection of C57BL6, and PLAT knock-out mice
Adjusted p-valueLog2-fold change
3.7317 × 10-2-1.6
Clca3a1'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
8.5672 × 10-131.5
Clca3a1'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
2.6812 × 10-111.5
Clca3a1'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.98 × 10-71.5
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.2109 × 10-6-1.5
Clca3a1'PUGKO' vs 'wild type'genotypeExpression profiling of the uteri of progesterone induced uterine gland knockout mice
Adjusted p-valueLog2-fold change
3.6772 × 10-5-1.5
Clca3a1'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.9976 × 10-41.5
Clca3a1'hyperoxia' vs 'control' in 'female'sex, stimulusTranscription profiling by array of lung tissues from wild-type male and female C56BL/6J mice either maintained in room air or exposed to hyperoxia (FiO2>95%) for 48 hours
Adjusted p-valueLog2-fold change
4.0399 × 10-41.5
Clca3a1'colitis' at '12 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
1.3954 × 10-31.5
Clca3a1'high fat diet' vs 'regular chow diet' in 'wild type genotype'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
2.3777 × 10-31.5
Clca3a1'SARS coronavirus MA15' vs 'none' at '1 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
4.8819 × 10-31.5
Clca3a1'8 month; diabetes mellitus' vs '8 month; normal'age, diseaseGene expression in OVE26 diabetic kidney during the development of nephropathy
Adjusted p-valueLog2-fold change
5.2507 × 10-31.5
Clca3a1'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.6059 × 10-2-1.5
Clca3a1'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
1.8869 × 10-2-1.5
Clca3a1'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
2.6446 × 10-2-1.5
Clca3a1'2.8 microgram per day adrenocorticotropic hormone' vs 'none'compoundTranscription profiling by array of mouse kidneys after chronic adrenocorticotropic hormone treatment
Adjusted p-valueLog2-fold change
3.2147 × 10-21.5
Clca3a1'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
1.1176 × 10-20-1.4
Clca3a1'interferon gamma; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
5.2766 × 10-11-1.4
Clca3a1'embryo transfer' vs 'no embryo transfer'stimulusRNA-seq of whole mouse placentas at E10.5 comparing C57Bl/6 male conceptuses that had undergone blastocyst transfer to non-transferred C57Bl/6 male conceptuses
Adjusted p-valueLog2-fold change
6.3348 × 10-8-1.4
Clca3a1'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
6.0006 × 10-71.4
Clca3a1'SARS coronavirus MA15; 4 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.3076 × 10-61.4
Clca3a1'CD36 knockout' vs 'wild type genotype' in 'none'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
9.386 × 10-6-1.4
Clca3a1'30 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
9.5507 × 10-6-1.4
Clca3a1'21 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.8494 × 10-41.4
Clca3a1'olfactory bulbectomy' at '1 day' vs 'untreated' at '0 day'clinical treatment, timeTranscription profiling by array of olfactory epithelium from mice after surgical removal of olfactory bulb.
Adjusted p-valueLog2-fold change
2.3952 × 10-4-1.4
Clca3a1'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
3.5489 × 10-41.4
Clca3a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
8.32 × 10-41.4
Clca3a1'Klf1-/-' vs 'wild type'genotypeNovel roles for Klf1 in regulating the erythroid transcriptome revealed by mRNA-seq
Adjusted p-valueLog2-fold change
1.3979 × 10-31.4
Clca3a1'anti mTNF-alpha; 250 microgram' vs 'saline' in 'wild type; Mycobacterium tuberculosis H37Rv'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
1.4313 × 10-31.4
Clca3a1'17-beta estradiol; 0.05 milligram; continuous release pellets over 60 days' vs 'none' in 'K14E7 transgenic'compound, genotype, treatmentGENE EXPRESSION PROFILE REGULATED BY THE HPV16-E7 ONCOPROTEIN AND ESTRADIOL IN CERVICAL TISSUE
Adjusted p-valueLog2-fold change
2.4284 × 10-3-1.4
Clca3a1'Crx knockout' vs 'control' at '6 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
2.7635 × 10-31.4
Clca3a1'17.5 Gray; X-radiation' vs 'none' at '8 week'irradiate, timeSenescence gene signature of radiation fibrosis
Adjusted p-valueLog2-fold change
2.8031 × 10-31.4
Clca3a1'apoE knock-out' vs 'wild type'genotypeTranscription profiling by array of aorta from apoE knock-out mice
Adjusted p-valueLog2-fold change
6.1267 × 10-31.4
Clca3a1'hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
7.3412 × 10-31.4
Clca3a1'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
7.6643 × 10-31.4
Clca3a1'Mettl6 knockout clone G6' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
1.1604 × 10-21.4
Clca3a1'H9; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
1.1943 × 10-21.4
Clca3a1'dexamethasome' vs 'methyl beta-clodextrin' in 'Nr1d1 homozygous knockout; 1 milligram per kilogram; ZT6'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
1.3911 × 10-21.4
Clca3a1'IkL/L mutant' vs 'wild type genotype'genotypeGene expression in WT and Ikaros-deficient LSK cells
Adjusted p-valueLog2-fold change
1.5465 × 10-2-1.4
Clca3a1'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
1.6824 × 10-2-1.4
Clca3a1'natural ingredient' vs 'control'dietLiver mRNA microarray study for mice treated with various diets
Adjusted p-valueLog2-fold change
4.5623 × 10-6-1.3
Clca3a1'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
9.8788 × 10-5-1.3
Clca3a1'Adjuvant System 03' vs 'PBS' in 'lymph node' at '6 hour'organism part, stimulus, timeExpression data from draining lymph node and muscle of mice immunised with AS03 or PBS
Adjusted p-valueLog2-fold change
2.1569 × 10-41.3
Clca3a1'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
2.1602 × 10-41.3
Clca3a1'hyperoxia' vs 'control' in 'male'sex, stimulusTranscription profiling by array of lung tissues from wild-type male and female C56BL/6J mice either maintained in room air or exposed to hyperoxia (FiO2>95%) for 48 hours
Adjusted p-valueLog2-fold change
2.1886 × 10-4-1.3
Clca3a1'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
4.0647 × 10-41.3
Clca3a1'3 day' vs '1 day' in 'influenza A infected C57BL/6J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
1.0756 × 10-31.3
Clca3a1'db/db' vs 'wild type genotype' in 'Gabpa miRNA; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.2773 × 10-3-1.3
Clca3a1'10 day' vs '0 day'ageTime course analysis of the cardiac transcriptome in the neonatal period
Adjusted p-valueLog2-fold change
1.8428 × 10-31.3
Clca3a1'transgenic hepatic growth hormone and hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '40 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
2.2226 × 10-3-1.3
Clca3a1'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2'genotype, irradiateRNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy
Adjusted p-valueLog2-fold change
3.2443 × 10-31.3
Clca3a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
7.2186 × 10-3-1.3
Clca3a1'FXR KO' vs 'wild type genotype'genotypeTranscription profiling by array of liver samples from FXR+/+ (wt) and liver-specific FXR KO (lKO) mice
Adjusted p-valueLog2-fold change
7.9783 × 10-31.3
Clca3a1'17-beta estradiol; 0.05 milligram; continuous release pellets over 60 days' vs 'none' in 'FvB'compound, genotype, treatmentGENE EXPRESSION PROFILE REGULATED BY THE HPV16-E7 ONCOPROTEIN AND ESTRADIOL IN CERVICAL TISSUE
Adjusted p-valueLog2-fold change
9.7833 × 10-31.3
Clca3a1'STAT1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '5 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
1.071 × 10-21.3
Clca3a1'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '4 day'genotype, infect, timeSM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Adjusted p-valueLog2-fold change
1.2414 × 10-21.3
Clca3a1'TAZ S89A' vs 'Empty vector' at '48 hour'genotype, timeTranscription profiling by array of mouse primary myoblasts constitutively expressing Hippo pathway downstream effectors Yap or Taz against empty vector controls
Adjusted p-valueLog2-fold change
1.3746 × 10-21.3
Clca3a1'endothelial mTOR knockout' vs 'wild type genotype' in '3 month'age, genotypeRNA from young and aged mouse hematopoietic stem cells
Adjusted p-valueLog2-fold change
1.6373 × 10-21.3
Clca3a1'adipogenic' vs 'non-adipogenic'phenotypeTranscription profiling by array of mouse sublines of Swiss 3T3 fibroblasts with varying potential for adipogenesis
Adjusted p-valueLog2-fold change
2.0418 × 10-2-1.3
Clca3a1'gallic acid; 15 microgram per milliliter' vs 'none' in 'CKIαΔgut/p53R172H; jejunum'compound, genotype, organism partRNAseq of enterocytes of the jejunum and Ileum from transgene C57BL/6 mice harboring a CKIαΔgut knock-out
Adjusted p-valueLog2-fold change
2.6768 × 10-21.3
Clca3a1'granulocyte-colony stimulating factor' vs 'PBS'treatmentHematopoietic stem cells from mice treated with G-CSF or saline alone for 36 hours
Adjusted p-valueLog2-fold change
2.7016 × 10-21.3
Clca3a1'HDAC4het' vs 'wild type genotype'genotypeGene expression data from cortex of 9 week old wild type, R6/2, HDAC4het and R6/2::HDAC4het mice
Adjusted p-valueLog2-fold change
3.1323 × 10-21.3
Clca3a1'olfactory bulbectomy' at '5 day' vs 'untreated' at '0 day'clinical treatment, timeTranscription profiling by array of olfactory epithelium from mice after surgical removal of olfactory bulb.
Adjusted p-valueLog2-fold change
3.2219 × 10-2-1.3
Clca3a1'Hox6 mutant' vs 'wild type'genotypeComparison of Hox6 mutant and control E12.5 mouse pancreas
Adjusted p-valueLog2-fold change
3.2639 × 10-21.3
Clca3a1'double Fancc-/- Fancg-/-' vs 'wild type'genotypeTranscription profiling by array of bone marrow cells from wild type, Fancc-deficient, Fancg-deficient, and doubly deficient (Fancc/Fancg) mice
Adjusted p-valueLog2-fold change
3.2929 × 10-21.3
Clca3a1'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'control; 36 hour after partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
3.5166 × 10-21.3
Clca3a1'18 month' vs '2 month' in 'DBA/2J'age, strainTranscription profiling by array of ageing mouse lung
Adjusted p-valueLog2-fold change
4.4069 × 10-2-1.3
Clca3a1'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
3.6047 × 10-91.2
Clca3a1'epithelium-specific Apc knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
7.3739 × 10-9-1.2
Clca3a1'Rfx2 knock out' vs 'wild type genotype'genotypeNext Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes at post natal day 21 [RNA-Seq P21]
Adjusted p-valueLog2-fold change
1.3935 × 10-71.2
Clca3a1'3110043O21Rik knockout; liver' vs 'wild type genotype; liver'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
4.4745 × 10-71.2
Clca3a1'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
1.5337 × 10-61.2
Clca3a1'16 day' vs '0 day'ageGene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26)
Adjusted p-valueLog2-fold change
3.6557 × 10-61.2
Clca3a1'3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
4.7614 × 10-6-1.2
Clca3a1'Irgm1 knockout' vs 'wild type genotype' in 'bone marrow'genotype, organism partRNA-Seq of bone marrow derived macophages (BMDMs) and brain tissue isolated from wild type and Irgm1 knockout mice
Adjusted p-valueLog2-fold change
5.7474 × 10-51.2
Clca3a1'wild type; SARS MA15; 7 day' vs 'wild type; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
6.131 × 10-5-1.2
Clca3a1'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'white adipose tissue'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
7.1571 × 10-5-1.2
Clca3a1'14 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
7.4831 × 10-51.2
Clca3a1'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day'genotype, infect, timeSM015 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1a/1b knockouts
Adjusted p-valueLog2-fold change
8.2286 × 10-51.2
Clca3a1'7 days P. chabaudi infected' vs 'uninfected' in 'intact male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
8.1348 × 10-4-1.2
Clca3a1'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '10 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
9.344 × 10-41.2
Clca3a1'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
1.2694 × 10-31.2
Clca3a1'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.2866 × 10-3-1.2
Clca3a1'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.3296 × 10-31.2
Clca3a1'control mice [Gp130f/f]; cecal ligation and puncture' vs 'control mice [Gp130f/f]; control'genotype, treatmentHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Adjusted p-valueLog2-fold change
1.5129 × 10-31.2
Clca3a1'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day'genotype, infect, timeSM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Adjusted p-valueLog2-fold change
1.839 × 10-3-1.2
Clca3a1'wild type; treated with angiotensin II and a combination of hydralazine and hydrochlorothiazide' vs 'wild type; vehicle'genotype, treatmentEffect of Hypertension of Dendritic Cell Gene Expression
Adjusted p-valueLog2-fold change
3.4768 × 10-31.2
Clca3a1'side population cells' vs 'main population cells' in 'muscle'cell type, organism partGene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow
Adjusted p-valueLog2-fold change
4.0122 × 10-31.2
Clca3a1'Klf5 knockout' vs 'wild type Klf5'genotypeExpression data from conditional Klf5 knockout Pten-null mouse prostates
Adjusted p-valueLog2-fold change
4.2595 × 10-31.2
Clca3a1'transgenic hepatic growth hormone' vs 'wild type genotype' in '40 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
5.7822 × 10-31.2
Clca3a1'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
1.264 × 10-2-1.2
Clca3a1'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
1.3126 × 10-2-1.2
Clca3a1'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'BALB/cByJ'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
3.5727 × 10-21.2
Clca3a1'Hnf4a conditional knockout' vs 'wild type genotype'genotypeTranscription profiling of mouse conditional intestinal epithelial Hnf4Ialpha knockout to investigate the role of HNF4alpha in the adult colon
Adjusted p-valueLog2-fold change
4.3485 × 10-21.2
Clca3a1'dextran sodium sulphate induced colitis' vs 'normal' in 'water'compound, diseaseTranscription profiling by array of murine colon tissue after exposure to 4% dextran sodium sulphate (DSS) for 6 days followed by 4 days of water or 1% L-arginine to study the effect of L-arginine on DSS-induced colitis
Adjusted p-valueLog2-fold change
1.552 × 10-81.1
Clca3a1'Mycobacterium tuberculosis H37Rv' vs 'none' in 'wild type'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
8.1833 × 10-8-1.1
Clca3a1'organoid culture without Noggin (ER medium)' vs 'organoid culture (ENR medium)' in 'none'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
7.7967 × 10-71.1
Clca3a1'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '4 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
3.0386 × 10-4-1.1
Clca3a1'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.2369 × 10-41.1
Clca3a1'olfactory bulbectomy' at '7 day' vs 'untreated' at '0 day'clinical treatment, timeTranscription profiling by array of olfactory epithelium from mice after surgical removal of olfactory bulb.
Adjusted p-valueLog2-fold change
5.4153 × 10-41.1
Clca3a1'SARS coronavirus MA15; 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.576 × 10-4-1.1
Clca3a1'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.0428 × 10-31.1
Clca3a1'NEMO knockout' vs 'wild type'genotypeTNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice.
Adjusted p-valueLog2-fold change
1.1416 × 10-31.1
Clca3a1'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
1.2162 × 10-31.1
Clca3a1'SARS coronavirus MA15' vs 'none' in 'Tnfrsf1a/1b -/-' at '7 day'genotype, infect, timeSM015 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1a/1b knockouts
Adjusted p-valueLog2-fold change
2.0391 × 10-31.1
Clca3a1'transgenic hepatic growth hormone' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
3.0326 × 10-31.1
Clca3a1'transgenic' vs 'wild type' in '121 day; 129Sv'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
3.0698 × 10-31.1
Clca3a1'LDB1 knock-down with full-length Ldb1 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
4.0167 × 10-31.1
Clca3a1'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
4.6092 × 10-31.1
Clca3a1'blocked acetylation on lysine 7 residues of RNA Pol II subunit RPB1' vs 'control'phenotypeTranscription profiling by array of NIH/3T3 fibroblasts with blocked acetylation on lysine 7 residues of RNA Pol II subunit RPB1 C-terminal domain because of lysine to arginine substitutions against wild type controls with normal acetylation
Adjusted p-valueLog2-fold change
6.4134 × 10-3-1.1
Clca3a1'Abcc8 knockout' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of pancreatic beta cells from wild type and Abcc8 knockout mice
Adjusted p-valueLog2-fold change
7.7693 × 10-31.1
Clca3a1'4 day' vs '1 day' in 'influenza A infected C57BL/6J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
9.3926 × 10-31.1
Clca3a1'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
1.1187 × 10-21.1
Clca3a1"98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young"age, phenotypeRNAseq of whole ovarian follicles from young and old mice.
Adjusted p-valueLog2-fold change
1.5959 × 10-21.1
Clca3a1'IFNAR1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '2 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
4.1533 × 10-2-1.1
Clca3a1'hematopoietic stem cell and hematopoietic multipotent progenitor cell' vs 'common myeloid progenitor'cell typeTranscription profiling by high throughput sequencing between multipotent hematopoietic stem progenitor cells LS+K) and myeloid committed cells (LS−K) of the mouse bone marrow
Adjusted p-valueLog2-fold change
4.1863 × 10-2-1.1
Clca3a1'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
4.2256 × 10-21.1
Clca3a1'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
4.9313 × 10-21.1
Clca3a1'RA-treated' vs 'control' in 'wild type'genotype, treatmentGene expression data of untreated and RA-treated wild type and RXRα-deficient mice liver
Adjusted p-valueLog2-fold change
1.952 × 10-11-1
Clca3a1'interleukin-13 (Mus musculus); 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
4.2384 × 10-81
Clca3a1'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens
Adjusted p-valueLog2-fold change
6.5999 × 10-5-1
Clca3a1'tape stripping' vs 'control'treatmentTranscription profiling by array of mouse dorsal skin after tape stripping and treatment with winged bean extract.
Adjusted p-valueLog2-fold change
8.3414 × 10-5-1
Clca3a1'Influenza A virus' vs 'mock' in 'IgG1'infect, stimulusTranscription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza
Adjusted p-valueLog2-fold change
2.2649 × 10-4-1
Clca3a1'collagen sandwich' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.9984 × 10-41
Clca3a1'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
3.7314 × 10-4-1
Clca3a1'Adjuvant System 03' vs 'PBS' in 'lymph node' at '4 hour'organism part, stimulus, timeExpression data from draining lymph node and muscle of mice immunised with AS03 or PBS
Adjusted p-valueLog2-fold change
3.7889 × 10-41
Clca3a1'tamoxifen; autosomal dominant polycystic kidney disease' vs 'none; normal'compound, disease, timeExpression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC
Adjusted p-valueLog2-fold change
3.8256 × 10-41
Clca3a1'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 70 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
4.8516 × 10-41
Clca3a1'transverse aortic constriction' vs 'sham transverse aortic constriction'treatmentTranscriptional profiling of mouse heat left ventricle after dfferential cardiac remodeling in preload versus afterload.
Adjusted p-valueLog2-fold change
6.6102 × 10-4-1
Clca3a1'confluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
8.6059 × 10-4-1
Clca3a1'blocked NF-kB pathway' vs 'wild type genotype'genotypeTranscription profiling of total epidermis of embryonic day 14.5 mouse embryos with blocked NF-kB pathway
Adjusted p-valueLog2-fold change
1.0197 × 10-31
Clca3a1'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day'genotype, infect, timeSM020 - Infection with SARS MA15 of C57BL/6J mice and KEPI (ppp1r14c) knockouts
Adjusted p-valueLog2-fold change
1.6464 × 10-31
Clca3a1'7 days P. chabaudi infected' vs 'uninfected' in 'intact female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
2.1059 × 10-31
Clca3a1'2 day' vs '1 day' in 'influenza A infected C57BL/6J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
2.1451 × 10-31
Clca3a1'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.415 × 10-31
Clca3a1'SARS coronavirus MA15' vs 'none' in 'Tnfrsf1a/1b -/-' at '4 day'genotype, infect, timeSM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Adjusted p-valueLog2-fold change
3.3405 × 10-3-1
Clca3a1'CD2314 and BIO' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
3.3706 × 10-31
Clca3a1'Dicer knock out' vs 'wild type'genotypeTranscription profiling by array of mouse Dicer-deficient ooctyes
Adjusted p-valueLog2-fold change
4.2112 × 10-3-1
Clca3a1'BIO' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
4.4982 × 10-31
Clca3a1'PolgD257A knockout' vs 'control'genotypeGene expression profile of gastrocnemius muscle from D257A mice
Adjusted p-valueLog2-fold change
5.0593 × 10-3-1
Clca3a1'Lgr5-Cre-ERT2; Il22-/-' vs 'Lgr5-Cre-ERT2' in 'none'genotype, irradiateRNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy
Adjusted p-valueLog2-fold change
6.3739 × 10-31
Clca3a1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
7.9299 × 10-31
Clca3a1'side population cells' vs 'main population cells' in 'bone marrow'cell type, organism partGene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow
Adjusted p-valueLog2-fold change
8.267 × 10-31
Clca3a1'hepatocyte-specific Pten knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
8.3151 × 10-31
Clca3a1'conditional UPF2 knockout; before partial hepatechtomy' vs 'control; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
1.1467 × 10-2-1
Clca3a1'liver-specific Pit1 knockout' vs 'wild type genotype' in 'high fat diet'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
1.1797 × 10-2-1
Clca3a1'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '14 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
1.3349 × 10-21
Clca3a1'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'conditional UPF2 knockout; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
1.3396 × 10-21
Clca3a1'Plasmodium berghei ANKA' at '7 day' vs 'none' at '0 day' in 'none'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
1.4015 × 10-2-1
Clca3a1'5 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance
Adjusted p-valueLog2-fold change
1.4422 × 10-21
Clca3a1'transgenic' vs 'wild type' in '111 day; 129Sv'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
1.9383 × 10-2-1
Clca3a1'4 hours after hCG treatment' vs 'control' in 'Snfl2 Ex6DEL'genotype, treatmentThe ISWI ATPase Snf2L is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells
Adjusted p-valueLog2-fold change
2.2395 × 10-21
Clca3a1'Zfx fl/y CreER; infected with control retrovirus with GFP selectable marker' vs 'wild type; infected with control retrovirus with GFP selectable marker'genotype, treatmentEffect of genetic Zfx deletion on Myc induced gene expression in bone marrrow myeloid progenitors
Adjusted p-valueLog2-fold change
2.6291 × 10-21
Clca3a1'Sgpp2 knockout' vs 'wild type' in 'normal'diet, genotypeTranscription profiling by array of pancreatic islets from Sgpp2 knockout mice after high fat diet
Adjusted p-valueLog2-fold change
2.8431 × 10-21
Clca3a1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 2 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
2.8572 × 10-2-1
Clca3a1'SARS coronavirus MA15 dORF6' vs 'SARS coronavirus MA15' at '1 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
3.5901 × 10-2-1
Clca3a1'20 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance
Synonym
Clca1
Ortholog
CLCA3 (Bos taurus), ENSMMUG00000000813 (Macaca mulatta), ENSCING00000022759 (Bos taurus), ENSCING00000017522 (Ciona intestinalis), ENSPTRG00000051840 (Pan troglodytes), ENSBTAG00000021501 (Bos taurus), ENSOCUG00000003548 (Oryctolagus cuniculus), ENSCSAVG00000009594 (Ciona savignyi), ENSCSAVG00000009591 (Ciona savignyi), ENSCSAVG00000010665 (Ciona savignyi), ENSCSAG00000001438 (Chlorocebus sabaeus), ENSOANG00000013532 (Ornithorhynchus anatinus), ENSPANG00000031611 (Papio anubis), ENSCSAVG00000006704 (Ciona savignyi), ENSOARG00020002384 (Ciona savignyi), ENSCING00000003293 (Ciona intestinalis), ENSOARG00020003537 (Ciona savignyi), ENSCING00000007114 (Salmo salar), ENSPTRG00000044041 (Pan troglodytes), ENSDNOG00000040224 (Dasypus novemcinctus), ENSPANG00000004994 (Papio anubis), Clca5 (Rattus norvegicus), ENSECAG00000014656 (Equus caballus), ENSCING00000001920 (Ciona intestinalis), ENSMODG00000008041 (Monodelphis domestica), ENSCSAVG00000011546 (Ciona savignyi), ENSCING00000020402 (Ciona intestinalis), ENSCSAVG00000009545 (Ciona savignyi), ENSGGOG00000043302 (Gorilla gorilla)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
A_52_P669035, 5231606, 4669949, 103812_at, 1417852_x_at, 4780828, 4755193, 4826120, 5480012, 10502552, 5297046, ILMN_2731377, A_55_P2039694, 5306925, 5124611, 17410845, A_55_P1982291, 4570909, 4718637, 4542675, 5256868, 1417853_at, 5109806