ENSMUSG00000057098 (Ebf1)

mus musculus

early B cell factor 1

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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3
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Duda et al., 2018 - organism part - …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.6699 × 10-24-6.4
Ebf1'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.0906 × 10-57-6.1
Ebf1'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
6.3097 × 10-75.2
Ebf1'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.9395 × 10-175
Ebf1'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
2.1412 × 10-94.7
Ebf1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
1.2134 × 10-5-4.7
Ebf1'Rb;E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.0916 × 10-764.4
Ebf1'Elp3fl/fl Trp53fl/fl vav-iCreT/+' vs 'Elp3fl/fl vav-iCreT/+' in 'myeloid lineage restricted progenitor cell'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
4.023 × 10-6-4.4
Ebf1'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.5449 × 10-4-4.2
Ebf1'Sox17.Epi' vs 'Sox17.Endo'genotypeTranscription profiling by high throughput sequencing of Sox17.Epi and Endo cells from mouse embryos
Adjusted p-valueLog2-fold change
8.8708 × 10-3-3.9
Ebf1'CD47 knockdown; cell from embryoid body-like cluster’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
2.2439 × 10-17-3.8
Ebf1'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
3.1003 × 10-4-3.7
Ebf1'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
7.807 × 10-6-3.6
Ebf1'E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.266 × 10-2-3.5
Ebf1'CD47 knockdown; endothelial’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
1.1873 × 10-11-3.4
Ebf1'Insm1-expressing endocrine progenitor cell' vs 'Insm1-lacking endocrine progenitor cell' in 'embryonic day 15.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
8.3949 × 10-7-3.4
Ebf1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.5972 × 10-43.3
Ebf1'P19; transduced with NeuroD2 lentivirus' vs 'P19; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
2.0266 × 10-21-3.2
Ebf1'TRIM28(flox/flox):Mx1Cre' vs 'TRIM28(flox/flox)' in 'CD71(hi)TER119-'genotype, phenotypeTranscription profiling by high throughput sequencing of bone marrow immature erythroid cells from Trim28flox/flox:TgMx1Cre congenic mice
Adjusted p-valueLog2-fold change
6.6531 × 10-133.2
Ebf1'doxycycline-induced expression of NGN3' vs 'control' at '48 hour'time, treatmentTranscription profiling by array of mouse embryonic stem cells expressing the transcription factor NGN3 for 12 hours, 24 hours and 48 hours
Adjusted p-valueLog2-fold change
1.3312 × 10-3-3.2
Ebf1'Fancc-/-' vs 'wild type'genotypeTranscription profiling by array of bone marrow cells from wild type, Fancc-deficient, Fancg-deficient, and doubly deficient (Fancc/Fancg) mice
Adjusted p-valueLog2-fold change
1.0946 × 10-18-3.1
Ebf1'Drosha -/-' vs 'wild type genotype'genotypeRNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs
Adjusted p-valueLog2-fold change
4.3869 × 10-6-3.1
Ebf1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
2.5668 × 10-5-3.1
Ebf1'144 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
2.0616 × 10-3-3.1
Ebf1'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
1.8149 × 10-2-3.1
Ebf1'malignant peritoneal mesothelioma; hi SV40 virus large TAg genotype (hiTAg)' vs 'malignant peritoneal mesothelioma; wild type genotype'disease, genotypeGene expression profiles in MexTAg transgenic mouse and wild type mouse asbestos-induced mesothelioma
Adjusted p-valueLog2-fold change
2.1037 × 10-11-3
Ebf1'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
7.9682 × 10-5-3
Ebf1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '30 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
8.9774 × 10-53
Ebf1'renin-expression' vs 'control'phenotypeExpression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein.
Adjusted p-valueLog2-fold change
3.8803 × 10-3-3
Ebf1'4 joule per square meter ultraviolet light' vs 'none' in 'wild type'genotype, irradiateTranscription profiling by array of mouse wild type and DNA-repair-deficient primary dermal fibroblasts after treatment with ultraviolet radiation
Adjusted p-valueLog2-fold change
6.2114 × 10-33
Ebf1'110 week' vs '8 week'ageTranscription profiling by array of CD11C+ splenic dendritic cells from young (8 weeks) and old (110 weeks) mice treated with Poly I:C for 4 hours
Adjusted p-valueLog2-fold change
3.7208 × 10-2-3
Ebf1'glioma' vs 'normal'diseaseGene expression profile between glioma associated macrophages and normal brain tissue associated macrophages
Adjusted p-valueLog2-fold change
2.7558 × 10-12-2.9
Ebf1'TRIM28(flox/flox):Mx1Cre' vs 'TRIM28(flox/flox)' in 'CD71(hi)TER119+'genotype, phenotypeTranscription profiling by high throughput sequencing of bone marrow immature erythroid cells from Trim28flox/flox:TgMx1Cre congenic mice
Adjusted p-valueLog2-fold change
4.508 × 10-9-2.9
Ebf1'anti-CD3/CSA' vs 'anti-CD3' in 'cyclosporine-sensitive'phenotype, treatmentActivating CD8 T cell clones via the T cell receptor complex in the absence and presence of cyclosporine A
Adjusted p-valueLog2-fold change
9.5583 × 10-7-2.9
Ebf1'tristetrapolin knockout' vs 'wild type' in 'none' at '0 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.3803 × 10-6-2.9
Ebf1'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.6571 × 10-17-2.8
Ebf1'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.784 × 10-10-2.8
Ebf1'MEF; transduced with MyoD lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
4.1736 × 10-52.8
Ebf1'interferon beta' vs 'none' in 'wild type; uninfected'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
1.9508 × 10-4-2.8
Ebf1'96 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
1.962 × 10-4-2.8
Ebf1'acute myeloid leukemia' vs 'myeloproliferative disorder'diseaseTranscription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm
Adjusted p-valueLog2-fold change
2.689 × 10-5-2.7
Ebf1'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
4.1175 × 10-10-2.6
Ebf1'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
6.9113 × 10-10-2.6
Ebf1'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
7.3531 × 10-10-2.6
Ebf1'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
8.6923 × 10-10-2.6
Ebf1'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
1.3173 × 10-9-2.6
Ebf1'30 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
7.9434 × 10-9-2.6
Ebf1'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.3439 × 10-42.6
Ebf1'Zbtb10 knockdown' vs 'control' at '6 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
2.9054 × 10-4-2.6
Ebf1'48 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
1.3373 × 10-4-2.5
Ebf1'Runx3 knockout' vs 'wild type genotype'genotypeRunx3 function in CD8+ splenic T cells
Adjusted p-valueLog2-fold change
2.1176 × 10-22.5
Ebf1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
7.1255 × 10-26-2.4
Ebf1'Nolz1-/-' vs 'wild type genotype'genotypeTranscriptomic (RNA-seq) analysis of wild-type and Nolz1-/- (Zfp503) mutant striatal tissue reveals altered expression of several genes involved in striatal projection neuron specification.
Adjusted p-valueLog2-fold change
2.1851 × 10-8-2.4
Ebf1'21 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.9721 × 10-7-2.4
Ebf1'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
8.14 × 10-6-2.4
Ebf1'Mkl1-RFP with a mutated SRF-interaction site' vs 'full length Mkl1-RFP'genotypeTranscription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1)
Adjusted p-valueLog2-fold change
3.9757 × 10-4-2.4
Ebf1'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
8.6475 × 10-42.4
Ebf1'Zbtb10 knockdown' vs 'control' at '2 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
4.0721 × 10-3-2.4
Ebf1'double Fancc-/- Fancg-/-' vs 'wild type'genotypeTranscription profiling by array of bone marrow cells from wild type, Fancc-deficient, Fancg-deficient, and doubly deficient (Fancc/Fancg) mice
Adjusted p-valueLog2-fold change
1.0621 × 10-2-2.4
Ebf1'expanded on HUVEC and m5GF in the presence of mD1R for 7 days' vs 'control'treatmentExpression data from cultured c-Kit+Sca-1+Lin- (KSL)cells
Adjusted p-valueLog2-fold change
5.3739 × 10-92.3
Ebf1'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
1.0269 × 10-5-2.3
Ebf1'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
1.4504 × 10-5-2.3
Ebf1'wild type; treated with angiotensin II and a combination of hydralazine and hydrochlorothiazide' vs 'wild type; vehicle'genotype, treatmentEffect of Hypertension of Dendritic Cell Gene Expression
Adjusted p-valueLog2-fold change
2.8915 × 10-32.3
Ebf1'Tfc knockout; normal' vs 'control'disease, genotypeGene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor.
Adjusted p-valueLog2-fold change
3.4364 × 10-3-2.3
Ebf1'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
6.1783 × 10-3-2.3
Ebf1"muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP negative"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
7.0765 × 10-3-2.3
Ebf1"muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP positive"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
6.741 × 10-17-2.2
Ebf1'lung carcinoma' vs 'normal' in 'lung cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
1.4762 × 10-8-2.2
Ebf1'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.6858 × 10-62.2
Ebf1'SMRT shRNA' vs 'none' in 'CpG' at '6 hour'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
6.0937 × 10-6-2.2
Ebf1'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.0566 × 10-4-2.2
Ebf1'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
4.2218 × 10-42.2
Ebf1'Ckit negative' vs 'Ckit positive'cell typeGene expression profile of c-kit positive and c-kit negative cells
Adjusted p-valueLog2-fold change
1.1426 × 10-3-2.2
Ebf1'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
5.0609 × 10-3-2.2
Ebf1'Fancg-/-' vs 'wild type'genotypeTranscription profiling by array of bone marrow cells from wild type, Fancc-deficient, Fancg-deficient, and doubly deficient (Fancc/Fancg) mice
Adjusted p-valueLog2-fold change
2.2205 × 10-22.2
Ebf1'dorsolateral nucleus motor neuron' vs 'lumbar motor neurons'cell typeComparison of gene expression in motor pools with differential vulnerability in ALS
Adjusted p-valueLog2-fold change
6.7997 × 10-15-2.1
Ebf1'proliferating progenitor' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
1.1136 × 10-11-2.1
Ebf1'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'endothelial cell; expressing AKT1'cell type, growth condition, phenotypeTranscription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture
Adjusted p-valueLog2-fold change
3.1415 × 10-52.1
Ebf1'carotid body' vs 'adrenal medulla'organism partExpression profile of mouse carotid body and adrenal medulla [RNA-Seq]
Adjusted p-valueLog2-fold change
9.7862 × 10-5-2.1
Ebf1'0.6 joule per square meter ultraviolet light' vs 'none' in 'csb mutant; xpa knock out'genotype, irradiateTranscription profiling by array of mouse wild type and DNA-repair-deficient primary dermal fibroblasts after treatment with ultraviolet radiation
Adjusted p-valueLog2-fold change
1.7554 × 10-3-2.1
Ebf1'inh-alpha/Tag transgenic' vs 'wild type' in 'none'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Adjusted p-valueLog2-fold change
3.7709 × 10-3-2.1
Ebf1'erythroblast' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
3.6188 × 10-22.1
Ebf1'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
4.0703 × 10-2-2.1
Ebf1'Tet2 knockout' vs 'wild type' in 'hematopoietic stem cell'cell type, genotypeTranscription profiling by high throughput sequencing of bone marrow stem and progenitor cells from Tet2 depleted mice
Adjusted p-valueLog2-fold change
1.0459 × 10-82
Ebf1'3 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
1.4578 × 10-6-2
Ebf1'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
4.6199 × 10-3-2
Ebf1"Evi1-GFP positive" vs "Evi1-GFP negative"phenotypeWhole genome expression profiling of Evi1-GFP positive and negative murine hematopoietic stem cell sub-populations.
Adjusted p-valueLog2-fold change
5.1734 × 10-32
Ebf1'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Adjusted p-valueLog2-fold change
4.1773 × 10-511.9
Ebf1'Zbtb2 -/-' vs 'wild type genotype' in 'EpiLC' at '1 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
2.0554 × 10-61.9
Ebf1'10 Gy Gray; x-ray' vs 'none' in 'tumor and stromal cell'cell type, irradiateRNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated
Adjusted p-valueLog2-fold change
5.5218 × 10-5-1.9
Ebf1'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
9.5226 × 10-5-1.9
Ebf1'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
3.4065 × 10-4-1.9
Ebf1'5,9-endoperoxy-cholest-7-en-3β,6α-diol' vs 'vehicle (cyclodextrin)'compound, timeArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
Adjusted p-valueLog2-fold change
1.4473 × 10-3-1.9
Ebf1'Ubc9 overexpression' vs 'wild type genotype' in 'undifferentiated; none'genotype, growth condition, stimulusSUMOylation promotes survival and integration of neural stem cell grafts in stroke
Adjusted p-valueLog2-fold change
4.4473 × 10-3-1.9
Ebf1'cancer' vs 'normal' in 'lymph node medullary sinus macrophage'cell type, diseaseRNA Sequencing of CD169+ lymph node macrophages isolated from naïve or tumor-bearing mice
Adjusted p-valueLog2-fold change
5.8024 × 10-3-1.9
Ebf1'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
1.208 × 10-2-1.9
Ebf1'total RNA; HRasV12 and c-Myc overexpression and Eif4e wild type' vs 'total RNA; wild type'fraction, genotypeRedefining the role of eIF4E dose in development, cancer, and protein synthesis
Adjusted p-valueLog2-fold change
1.3179 × 10-2-1.9
Ebf1'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
8.9301 × 10-8-1.8
Ebf1'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
1.1301 × 10-6-1.8
Ebf1'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
1.8078 × 10-6-1.8
Ebf1'Rag1-/-' vs 'wild type'genotypeTranscription profiling by array of peritoneal macrophages from B6 wild type and B6-Rag1 knock-out mice
Adjusted p-valueLog2-fold change
7.7009 × 10-5-1.8
Ebf1'24 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
8.6592 × 10-5-1.8
Ebf1'Staphylococcus aureus Sanger476; 6 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.0467 × 10-4-1.8
Ebf1'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
5.6479 × 10-31.8
Ebf1'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
3.9419 × 10-21.8
Ebf1'influenza' vs 'uninfected' in 'wild type'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
3.1366 × 10-81.7
Ebf1'129S1 allele at SNP rs50454566' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene
Adjusted p-valueLog2-fold change
5.6673 × 10-81.7
Ebf1'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD8-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
1.3759 × 10-6-1.7
Ebf1'interferon gamma' vs 'dexamethasone; 100 nanomolar'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
1.9824 × 10-5-1.7
Ebf1'0.6 joule per square meter ultraviolet light' vs 'none' in 'csb mutant'genotype, irradiateTranscription profiling by array of mouse wild type and DNA-repair-deficient primary dermal fibroblasts after treatment with ultraviolet radiation
Adjusted p-valueLog2-fold change
1.9398 × 10-4-1.7
Ebf1'wild type; mature luminal' vs 'wild type; MaSC/basal'cell type, genotypeExpression data from sorted control and Pygo2-null mouse mammary stem/basal cells
Adjusted p-valueLog2-fold change
3.8349 × 10-4-1.7
Ebf1'14 days P. chabaudi infected' vs 'uninfected' in 'intact male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
5.4913 × 10-4-1.7
Ebf1'CpG; 6 hour' vs 'none; 0 hour' in 'none'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
4.9224 × 10-3-1.7
Ebf1'fear conditioning' vs 'none'stimulusGene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage
Adjusted p-valueLog2-fold change
1.7202 × 10-2-1.7
Ebf1'megakaryocyte' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
1.6041 × 10-101.6
Ebf1'PH3 homozygous knockout' vs 'wild type phenotype'phenotypePHF3 binds RNA polymerase II via the SPOC domain and regulates transcription of neuronal genes - Mouse Embryonic Stem Cell RNAseq
Adjusted p-valueLog2-fold change
1.4842 × 10-6-1.6
Ebf1'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
2.1468 × 10-6-1.6
Ebf1'cholesterol' vs 'vehicle (cyclodextrin)'compound, timeArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
Adjusted p-valueLog2-fold change
6.0679 × 10-6-1.6
Ebf1'5-aza-2'-deoxycytidine; 5 micromolar' vs 'none'compoundTranscription profiling by array of mouse primary dermal fibroblasts after treatment with 5-aza-2'-deoxycytidine
Adjusted p-valueLog2-fold change
2.8003 × 10-5-1.6
Ebf1'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
7.9736 × 10-4-1.6
Ebf1'p48-Cre;KrasG12D;Ela-Tgfa' vs 'wild type'genotypeTranscription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice
Adjusted p-valueLog2-fold change
2.309 × 10-3-1.6
Ebf1'0.6 joule per square meter ultraviolet light' vs 'none' in 'xpa knock out'genotype, irradiateTranscription profiling by array of mouse wild type and DNA-repair-deficient primary dermal fibroblasts after treatment with ultraviolet radiation
Adjusted p-valueLog2-fold change
5.1952 × 10-31.6
Ebf1'Elp3fl/fl vav-iCreT/+' vs 'Elp3fl/fl' in 'polysome associated RNA'fraction, genotypePolysome profiling analysis of myeloid progenitors of control mice or mice conditionally deficient for Elp3 in the hematopoietic system
Adjusted p-valueLog2-fold change
2.1879 × 10-2-1.6
Ebf1'normal skin; PKC alpha-/-' vs 'normal skin; wild type genotype'clinical history, genotypeAltered dermal architecture in PKCα-/- skin
Adjusted p-valueLog2-fold change
4.4553 × 10-271.5
Ebf1'Zbtb2 -/-' vs 'wild type genotype' in 'EpiLC' at '2 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
3.1588 × 10-13-1.5
Ebf1'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens
Adjusted p-valueLog2-fold change
5.3397 × 10-7-1.5
Ebf1'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.6166 × 10-6-1.5
Ebf1'14 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
4.6223 × 10-61.5
Ebf1'nuclear translocation of Mbd3b' at '48 hour' vs 'none' at '0 hour'stimulus, timeTranscription profiling by RNA-seq during NuRD complex induction in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
7.2613 × 10-6-1.5
Ebf1'14 days P. chabaudi infected' vs 'uninfected' in 'intact female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
9.1071 × 10-6-1.5
Ebf1'induced neural stem cell' vs 'neural stem cell'cell typeGene expression profile of mouse induced neural stem cells
Adjusted p-valueLog2-fold change
5.3293 × 10-5-1.5
Ebf1Synacthen vs sodium chloride controlcompoundTranscription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses.
Adjusted p-valueLog2-fold change
6.7358 × 10-51.5
Ebf1'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
7.6858 × 10-51.5
Ebf1'osteoblast culture 9 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
1.2414 × 10-4-1.5
Ebf1'Staphylococcus aureus Sanger476; 4 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
5.5704 × 10-4-1.5
Ebf1'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.191 × 10-31.5
Ebf1'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
4.5324 × 10-31.5
Ebf1'Stella knockout' vs 'wild type genotype' in 'oocyte'developmental stage, genotypeTranscription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development
Adjusted p-valueLog2-fold change
6.0438 × 10-31.5
Ebf1'masseter muscle' vs 'tibialis anterior'organism partTranscription profiling of mouse masseter and tibialis anterior muscles to determine expression differences between muscle groups
Adjusted p-valueLog2-fold change
1.2311 × 10-21.5
Ebf1'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
1.3926 × 10-21.5
Ebf1'PS2APP transgenic' vs 'non transgenic' in 'astrocyte' at '13 month'age, cell type, genotypeTranscription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model
Adjusted p-valueLog2-fold change
2.5578 × 10-2-1.5
Ebf1'polysomal RNA; HRasV12 and c-Myc overexpression and Eif4e wild type' vs 'polysomal RNA; wild type'fraction, genotypeRedefining the role of eIF4E dose in development, cancer, and protein synthesis
Adjusted p-valueLog2-fold change
3.2151 × 10-21.5
Ebf1'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
2.4409 × 10-151.4
Ebf1'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
3.7865 × 10-61.4
Ebf1'chronic pancreatitis' vs 'control'diseasePancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
Adjusted p-valueLog2-fold change
5.1939 × 10-6-1.4
Ebf1'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
8.6217 × 10-5-1.4
Ebf1'7 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
3.6205 × 10-4-1.4
Ebf1'trypsinized and mock FACS sorted' vs 'untreated'treatmentExpression data from mammary epithelial cells harvested from 8-9 week old C3H female mice - various isolation conditions
Adjusted p-valueLog2-fold change
6.5259 × 10-4-1.4
Ebf1"YFP positive" vs "YFP negative" in "lamina propria of small intestine"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
5.3706 × 10-3-1.4
Ebf1'Nix knock out' vs 'wild type'genotypeTranscription profiling by array of spleens from mice with Nix knocked out.
Adjusted p-valueLog2-fold change
5.8877 × 10-3-1.4
Ebf1'Sdhb knockout' vs 'wild type'genotype, phenotypeGene expression analysis of SDH-deficient immortalized mouse kidney epithelial cells
Adjusted p-valueLog2-fold change
7.2663 × 10-3-1.4
Ebf1'Trypanosoma brucei STIB247' vs 'uninfected'infectTranscription profiling by array of spleens from mice infected with different Trypanosoma brucei strains
Adjusted p-valueLog2-fold change
4.8574 × 10-81.3
Ebf1'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
8.5685 × 10-6-1.3
Ebf1'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
2.0044 × 10-5-1.3
Ebf1'overexpression of alpha- and beta- Hb chains' vs 'control vector'genotypeUnexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells
Adjusted p-valueLog2-fold change
3.1775 × 10-41.3
Ebf1'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
3.5409 × 10-4-1.3
Ebf1'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
5.8288 × 10-4-1.3
Ebf1'Staphylococcus aureus USA300; 2 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.0435 × 10-31.3
Ebf1'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day'compound, genotype, timeTranscription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin
Adjusted p-valueLog2-fold change
8.0202 × 10-3-1.3
Ebf1'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
8.6692 × 10-3-1.3
Ebf1'smoke; 1500 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
3.7477 × 10-7-1.2
Ebf1'10 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
3.4721 × 10-6-1.2
Ebf1'7 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
2.2944 × 10-51.2
Ebf1'dexamethasone; 100 nanomolar' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
2.0538 × 10-41.2
Ebf1'ko cyld-/-' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Cyld inactivation
Adjusted p-valueLog2-fold change
2.3271 × 10-41.2
Ebf1'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
3.4428 × 10-4-1.2
Ebf1'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
1.8814 × 10-3-1.2
Ebf1'TGF-beta1 5 nanograms per milliliter' vs 'none'compound, doseTGF-beta and BMP mediated gene expression in cultured sclerotome.
Adjusted p-valueLog2-fold change
2.6365 × 10-3-1.2
Ebf1'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
4.6773 × 10-3-1.2
Ebf1'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
5.4084 × 10-3-1.2
Ebf1'spontaneous lung tumor' vs 'normal'disease state, diseaseTranscription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer
Adjusted p-valueLog2-fold change
1.7533 × 10-21.2
Ebf1'12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
1.8572 × 10-2-1.2
Ebf1'Escherichia coli O18:K1:H7; 12 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.9101 × 10-21.2
Ebf1'oculomotor nucleus motor neurons' vs 'lumbar motor neurons'cell typeComparison of gene expression in motor pools with differential vulnerability in ALS
Adjusted p-valueLog2-fold change
6.2004 × 10-11-1.1
Ebf1'3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
9.3994 × 10-8-1.1
Ebf1'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
1.1704 × 10-71.1
Ebf1'ATF5 knockdown' vs 'wild type' in 'DMSO'compound, genotypeMicroarray to find ATF5 dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
3.1048 × 10-7-1.1
Ebf1'NrlGFP positive' vs 'NrlGFP negative'phenotypeTranscription profiling by array of photoreceptor precursor cells selected via cell surface antigen expression.
Adjusted p-valueLog2-fold change
3.2997 × 10-7-1.1
Ebf1'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
5.7691 × 10-7-1.1
Ebf1'6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
6.3976 × 10-5-1.1
Ebf1'5 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
7.5519 × 10-51.1
Ebf1'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
3.7789 × 10-4-1.1
Ebf1'acute oropharyngeal candidiasis wild type mice'; female' vs 'healthy wild type genotype mice'compound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
5.6695 × 10-4-1.1
Ebf1'Wnt1Cre Ezh2lox/lox' vs 'control'genotypeExpression data from E11.5 mouse branchial arch 1 (BA1) - comparison between Ezh2lox/lox and Wnt1Cre Ezh2lox/lox embryos
Adjusted p-valueLog2-fold change
5.8761 × 10-41.1
Ebf1'old neuronal stem cells' vs 'young neuronal stem cells'ageA mechanism for the segregation of age in mammalian neural stem cells
Adjusted p-valueLog2-fold change
6.1141 × 10-4-1.1
Ebf1'inducible knockout of Rif1 (Rif1-/-)' vs 'wild type genotype' in '4 days cre induction'genotype, growth conditionGene expression profiles of Rif1 inducible knock-out embryonic stem cells
Adjusted p-valueLog2-fold change
2.0216 × 10-3-1.1
Ebf1'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
1.0156 × 10-21.1
Ebf1'9 day' vs '0 day'timeTranscription profiling by array of mineralising murine vascular smooth muscle cell cultures over a nine day culture period to identify new regulators of vascular mineralization
Adjusted p-valueLog2-fold change
1.2331 × 10-2-1.1
Ebf1'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.2438 × 10-21.1
Ebf1'Roquinsan/san(sanroque)' vs 'wild type'genotypeExpression data from CD44loCD8+ T cells of sanroque versus wild-type mice
Adjusted p-valueLog2-fold change
1.2886 × 10-2-1.1
Ebf1'retinoic acid' vs 'none' in 'embryoid body' at '6 day'age, compound, phenotypeTranscription profiling of mouse embryonic stem cell line Sox1Tv2 during neuronal differentiation
Adjusted p-valueLog2-fold change
1.3693 × 10-2-1.1
Ebf1'dox-induced over-expression of oncogenes for 5 days then off 7 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
1.4528 × 10-21.1
Ebf1'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
1.5833 × 10-2-1.1
Ebf1'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
2.6557 × 10-21.1
Ebf1'bER knockout' vs 'wild type' in 'human chorionic gonadotropin; 5 International Unit'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Adjusted p-valueLog2-fold change
2.7637 × 10-21.1
Ebf1'Wls fl/fl ; Lecre +/-' vs 'wild type'genotypeWnt ligands from the embryonic surface ectoderm regulate bimetallic strip optic cup morphogenesis in the mouse
Adjusted p-valueLog2-fold change
3.0821 × 10-2-1.1
Ebf1'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
3.6762 × 10-21.1
Ebf1'Hnf1a knock out' vs 'wild type'genotypeTranscription profiling of pancreatic islets from Hnf1a-deficient and wild type mice
Adjusted p-valueLog2-fold change
4.7071 × 10-21.1
Ebf1'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.5665 × 10-13-1
Ebf1'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
1.9513 × 10-5-1
Ebf1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.6276 × 10-5-1
Ebf1'dinitrofluorobenzene' vs 'control' in 'wild type'compound, genotypeTranscription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity
Adjusted p-valueLog2-fold change
9.1378 × 10-5-1
Ebf1'LY294002' at '72 hour' vs 'control' at '72 hour'compound, timeTranscription profiling of mouse embyronic stem cells cultured with PI3-K signalling inhibitor LY294002 for different lengths of time to identify PI3K-target genes
Adjusted p-valueLog2-fold change
1.1761 × 10-41
Ebf1'chronic cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
1.287 × 10-4-1
Ebf1'Mkl1-RFP with a deletion of the SAP domain' vs 'full length Mkl1-RFP'genotypeTranscription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1)
Adjusted p-valueLog2-fold change
2.1044 × 10-4-1
Ebf1'acute oropharyngeal candidiasis' vs 'healthy' in wild type micecompound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
4.5427 × 10-4-1
Ebf1'Escherichia coli O18:K1:H7; 12 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.0773 × 10-31
Ebf1'20 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance
Adjusted p-valueLog2-fold change
1.1656 × 10-31
Ebf1'Mef2c deletion' vs 'wild type'phenotypeWhole transcriptome sequencing of mouse regulatory T cells with and without Mef2d, Mef2c, HDAC1, HDAC2 or Dyrk1 deletion
Adjusted p-valueLog2-fold change
1.4988 × 10-3-1
Ebf1'dominant-negative Brg1' vs 'wild type'genotypeTranscription profiling by array of lens tissue from mice expressing a dnBrg1 transgenic construct
Adjusted p-valueLog2-fold change
6.0791 × 10-3-1
Ebf1'Staphylococcus aureus USA100; 2 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
6.323 × 10-3-1
Ebf1'anti mTNF-alpha; 250 microgram' vs 'saline' in 'wild type; Mycobacterium tuberculosis H37Rv'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
6.5495 × 10-31
Ebf1'dexamethasone; 100 nanomolar; interferon gamma' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
1.0082 × 10-2-1
Ebf1'promyelocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
1.6006 × 10-21
Ebf1'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
1.7561 × 10-2-1
Ebf1'Ubc9 overexpression' vs 'wild type genotype' in 'undifferentiated; oxygen/glucose-deprivation followed by restoration of oxygen/glucose'genotype, growth condition, stimulusSUMOylation promotes survival and integration of neural stem cell grafts in stroke
Adjusted p-valueLog2-fold change
1.8462 × 10-2-1
Ebf1'Staphylococcus aureus USA300; 2 hour' vs 'none; 0 hour' in 'CD1'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.8627 × 10-2-1
Ebf1'bisphenol AF; 10 micromolar' vs 'vehicle'compoundTranscriptomic analyses of 11.5 dpc female germ cell (mouse) exposed or not to Bisphenol A analogues (BPAF and BADGE)
Adjusted p-valueLog2-fold change
1.9309 × 10-2-1
Ebf1'Staphylococcus aureus Sanger476; 4 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.1301 × 10-2-1
Ebf1'SARS coronavirus MA15 lacking full-length E protein' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
2.9181 × 10-2-1
Ebf1'9 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
3.4529 × 10-2-1
Ebf1'AZD5069; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
3.6779 × 10-21
Ebf1'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in '129S1/SvImJ'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Synonym
O/E-1, Olf-1, Olf1
Ortholog
EBF1 (Macaca mulatta), ENSCSAVG00000000458 (Ciona savignyi), EBF1 (Tetraodon nigroviridis), EBF1 (Ornithorhynchus anatinus), Ebf1 (Rattus norvegicus), EBF1 (Gallus gallus), EBF1 (Pan troglodytes), EBF1 (Homo sapiens), EBF1 (Oryctolagus cuniculus), si:ch211-51e8.2 (Danio rerio), ebf3a (Danio rerio), EBF1 (Anas platyrhynchos), EBF1 (Chlorocebus sabaeus), EBF1 (Monodelphis domestica), EBF1 (Equus caballus), ebf1b (Danio rerio), ebf4 (Xenopus tropicalis), ENSPANG00000010656 (Papio anubis), kn (Drosophila melanogaster), ENSOARG00020023107 (Salmo salar), EBF1 (Tetraodon nigroviridis), ENSCING00000003209 (Salmo salar), EBF1 (Sus scrofa), ENSACAG00000003097 (Anolis carolinensis), ENSDNOG00000036735 (Dasypus novemcinctus), EBF1 (Bos taurus), EBF1 (Pongo abelii), EBF1 (Gorilla gorilla), unc-3 (Caenorhabditis elegans)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4402907, 5568252, 4365799, 4719888, 4941749, 92535_at, 4842155, 5035176, 4998321, 4556976, 4867859, ILMN_2707452, 5029539, A_55_P2065513, 4804725, 4503710, 4340324, 114854_at, 1416302_at, 17248691, 5227939, 4790592, L12147_s_at, 4807194, 1448293_at, 5543922, 4476610, 4719839, 5134244, 1416301_a_at, A_51_P188054, 5249216, 4414199, 4790447, 5594887, ILMN_2573212, 4944313, 115110_at, 5232580, ILMN_1245076, 5069056, 4562527, 5493796, 4676893, 5142047, 5165544, 5006604, 4684725, 4456040, 10375358, 10375360, 4487006, 5396285, 1439789_at, 4704251