ENSMUSG00000068457 (Uty)

mus musculus

ubiquitously transcribed tetratricopeptide repeat containing, Y-linked

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Mus musculus
Organism part
Showing 2 experiments:
Created with Highcharts 6.2.0adult CCAP neuronalpha’/beta’ middle Kenyon cellcentrifugal neuron C3distal medullary amacrine neuron Dm10distal medullary amacrine neuron Dm9dopaminergic PAM neuron 6gamma dorsal Kenyon celllamina monopolar neuron L2lobula columnar neuron LC10alobula columnar neuron LC6lobula-lobula plate columnar neuron LLPC1mushroom body output neuronproximal medullary amacrine neuron Pm3transmedullary neuron Tm1transmedullary neuron Tm4adult lamina marginal glial cellalpha/beta posterior Kenyon cellcolumnar neuron T1distal medullary amacrine neuron Dm3dopaminergic PAM neuron 3dopaminergic PAM neuron 9lamina intrinsic neuronlamina monopolar neuron L5lobula columnar neuron LC10dlobula plate tangential neuronmedullary intrinsic neuron Mi4photoreceptor cell R7T neurontransmedullary neuron Tm29
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
7.2885 × 10-145-9.6
Uty'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
3.133 × 10-6-8.2
Uty'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
4.2034 × 10-273-7.9
Uty'Sall4 -/-' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells in response to changes in Sall4
Adjusted p-valueLog2-fold change
2.9557 × 10-1177.2
Uty'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
6.0906 × 10-66-6
Uty'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'co-culture'genotype, growth conditionRNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions
Adjusted p-valueLog2-fold change
2.4705 × 10-48-6
Uty'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2-GFP knockin; Egr2-GFP high'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
3.0077 × 10-282-5.7
Uty'Pbx1 -/-; Pbx2 -/-' vs 'wild type genotype' at '24 hour'genotype, timeRNA-seq of wild-type, Pbx1/Pbx2 double-knockout and pMsgn1-mut EpiSCs differentiated in vitro to pre-somitic mesoderm in the first 24 hours of differentiation.
Adjusted p-valueLog2-fold change
9.2723 × 10-292-5.6
Uty'Pbx1 -/-; Pbx2 -/-' vs 'wild type genotype' at '12 hour'genotype, timeRNA-seq of wild-type, Pbx1/Pbx2 double-knockout and pMsgn1-mut EpiSCs differentiated in vitro to pre-somitic mesoderm in the first 24 hours of differentiation.
Adjusted p-valueLog2-fold change
2.0339 × 10-105.4
Uty'70 week' vs '14 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
1.1161 × 10-85.2
Uty'BCL6 knockout and inducible BACH2 overexpression' vs 'wild type and inducible BACH2 overexpression'genotypeGene expression profile of BCR-ABL1 transformed pre-B mouse cells from BCL6 knockout after inducible overexpression of Bach2
Adjusted p-valueLog2-fold change
5.5413 × 10-247-5.1
Uty'Mettl6 knockout clone D1' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
1.4292 × 10-2374.9
Uty'K14-Cre-ERT2 / CK1α fl/fl; 4-hydroxytamoxifen; none; 7 day' vs 'K14-Cre-ERT2; none; none'genotype, irradiate, timeAblation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin
Adjusted p-valueLog2-fold change
4.7556 × 10-9-4.9
Uty'Wnt1Cre Ezh2lox/lox' vs 'control'genotypeExpression data from E11.5 mouse branchial arch 1 (BA1) - comparison between Ezh2lox/lox and Wnt1Cre Ezh2lox/lox embryos
Adjusted p-valueLog2-fold change
4.5755 × 10-64.7
Uty'V6.5; embryonic stem cell’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
2.437 × 10-1394.2
Uty'male' vs 'female'sexRNA-seq of vomeronasal tissue from adult male and female mice
Adjusted p-valueLog2-fold change
8.7617 × 10-16-4.2
Uty'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
1.1264 × 10-274.1
Uty'Setd5 homozygous (null) knockout' vs 'Setd5 heterozygous knockout'genotypeTranscriptional profiling of Setd5 heterozygous and knockout mouse embryonic stem cells
Adjusted p-valueLog2-fold change
2.8272 × 10-8-4.1
Uty'AZD5069; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
5.4187 × 10-17-4
Uty'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
1.7657 × 10-9-4
Uty'B117H; cytosine arabinoside resistant' vs 'B117P; cytosine arabinosine sensitive'cell line, phenotypeGene expression profile of two Ara-C-resistant cell lines
Adjusted p-valueLog2-fold change
1.0304 × 10-54
Uty'Setd2 knock out' vs 'wild type genotype'genotypeComparison of gene expression pattern between Wild-type and Setd2 knockout mESCs [Affymetrix]
Adjusted p-valueLog2-fold change
5.697 × 10-903.9
Uty'male' vs 'female' in 'PWD/Ph'sex, strainTranscription profiling by high throughput sequencing of hippocampus from adult males and females of six inbred strains of mice
Adjusted p-valueLog2-fold change
1.6248 × 10-1573.8
Uty'male' vs 'female' in 'A/J'sex, strainTranscription profiling by high throughput sequencing of hippocampus from adult males and females of six inbred strains of mice
Adjusted p-valueLog2-fold change
3.8612 × 10-73.7
Uty'p38alpha null' vs 'wild type genotype' in 'embryonic day 15.5'developmental stage, genotypeTranscription profiling of mouse embryonic day 13.5 and 15.5 fetal livers lacking p38alpha, a mitogen-activated kinase that controls inflammatory responses and cell proliferation
Adjusted p-valueLog2-fold change
6.5925 × 10-43.6
Uty'Nkx2-5 knockout' vs 'wild type'genotypeTranscription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse
Adjusted p-valueLog2-fold change
4.8525 × 10-3-3.6
Uty'19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '5 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
1.4366 × 10-3-3.5
Uty'19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
4.0321 × 10-43.4
Uty'Tbx5;Nkx2-5 knockout' vs 'wild type'genotypeTranscription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse
Adjusted p-valueLog2-fold change
4.9228 × 10-4-3.4
Uty'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
2.3117 × 10-1483.3
Uty'male' vs 'female' in 'C57BL/6J'sex, strainTranscription profiling by high throughput sequencing of hippocampus from adult males and females of six inbred strains of mice
Adjusted p-valueLog2-fold change
1.6162 × 10-23.2
Uty'ATF3 -/-' vs 'wild type' in 'none' at '0 hour'compound, genotype, timeTranscription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide
Adjusted p-valueLog2-fold change
1.9487 × 10-2-3.2
Uty'miR-1-133a_FGFR1_tKO' vs 'miR-1-133a_dKO'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
2.2782 × 10-7-3
Uty'CHOP-/-' vs 'wild type' in 'DMSO'compound, genotypeMicroarray to find CHOP dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
1.3555 × 10-23
Uty'myelocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
1.8153 × 10-23
Uty'ATF3 -/-' vs 'wild type' in '10 nanogram per milliliter; lipopolysaccharide' at '1 hour'compound, genotype, timeTranscription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide
Adjusted p-valueLog2-fold change
3.5015 × 10-2-3
Uty'UO126; 0.2 milligram per kilogram; miR-1-133a_dKO' vs 'miR-1-133a_dKO'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
4.426 × 10-23
Uty'NFAT5 knock-out' vs 'wild type' in 'none'compound, genotypeTranscription profiling by array of mouse bone marrow derived macrophages mutant for NAT5 after treatment with lipopolysaccharide
Adjusted p-valueLog2-fold change
1.9049 × 10-27-2.8
Uty'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
2.4378 × 10-42.8
Uty'MED23 knockout' vs 'wild type'genotypeMediator Med23-deficiency Enhances Neural Differentiation of Embryonic Stem Cells through Modulating BMP Signaling
Adjusted p-valueLog2-fold change
1.3503 × 10-22.8
Uty'ATF3 -/-' vs 'wild type' in '10 nanogram per milliliter; lipopolysaccharide' at '2 hour'compound, genotype, timeTranscription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide
Adjusted p-valueLog2-fold change
1.378 × 10-4-2.7
Uty'Alkbh1-/-' vs 'wild type'genotypeTranscription profiling by array of wild type and Alkbh1 knock out mouse embyronic stem cells
Adjusted p-valueLog2-fold change
1.9756 × 10-22.7
Uty'NFAT5 knock-out' vs 'wild type' in 'lipopolysaccharide'compound, genotypeTranscription profiling by array of mouse bone marrow derived macrophages mutant for NAT5 after treatment with lipopolysaccharide
Adjusted p-valueLog2-fold change
4.6008 × 10-22.7
Uty'6 week' vs '14 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
1.1259 × 10-52.5
Uty'acute graft versus host disease' vs 'normal'diseaseTranscription profiling by array of intestinal tissues from mice receiving bone marrow transplantation with or without T-cell stimulation
Adjusted p-valueLog2-fold change
1.392 × 10-22.5
Uty'spontaneous lung tumor' vs 'normal'disease state, diseaseTranscription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer
Adjusted p-valueLog2-fold change
3.6385 × 10-2-2.5
Uty'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
4.2027 × 10-22.5
Uty'mutant (Pdgfc-/-; Pdgfra GFP/+)' vs 'control'genotypeCerebral gene expression changes in Pdgfc and Pdgfra mutant
Adjusted p-valueLog2-fold change
2.1158 × 10-62.4
Uty'RAW264.7 macrophage cell line; control' vs 'bone marrow macrophage; control'cell type, growth conditionTranscription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line
Adjusted p-valueLog2-fold change
3.9579 × 10-2-2.4
Uty'Nrf knockout; air; 3 day' vs 'control; air; 3 day'genotype, growth condition, timeGene expression profile of NRf knockout newborn rodents exposed to hyperoxia
Adjusted p-valueLog2-fold change
5.6475 × 10-11-2.3
Uty'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.4717 × 10-7-2.3
Uty'Gprc5a knockout' vs 'control'genotypeGene expression profile of lung epithelial cells cultured from normal tracheas of Gprc5a knockout and wild-type mice
Adjusted p-valueLog2-fold change
2.704 × 10-62.3
Uty'Rag1-/-' vs 'wild type'genotypeTranscription profiling by array of peritoneal macrophages from B6 wild type and B6-Rag1 knock-out mice
Adjusted p-valueLog2-fold change
5.1959 × 10-52.3
Uty'Utx knockout' vs 'wild type' in 'spleen'genotype, organism partTranscription profiling by high throughput sequencing of mouse leukemia T cells with Utx knockout
Adjusted p-valueLog2-fold change
2.0524 × 10-4-2.3
Uty'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
7.1773 × 10-4-2.3
Uty'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'separate'genotype, growth conditionRNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions
Adjusted p-valueLog2-fold change
9.7523 × 10-8-2.2
Uty'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
4.8133 × 10-3-2.2
Uty'19BL; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
3.3397 × 10-792.1
Uty'male' vs 'female' in 'DBA/1J'sex, strainTranscription profiling by high throughput sequencing of hippocampus from adult males and females of six inbred strains of mice
Adjusted p-valueLog2-fold change
6.47 × 10-522.1
Uty'male' vs 'female' in '129S1/SvImJ'sex, strainTranscription profiling by high throughput sequencing of hippocampus from adult males and females of six inbred strains of mice
Adjusted p-valueLog2-fold change
8.7721 × 10-52.1
Uty'missense mutation (G9492A) in Mucin 2 (Muc2)' vs 'wild type genotype'genotypeTranscription profiling of mouse intestine in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
Adjusted p-valueLog2-fold change
1.1186 × 10-42.1
Uty'OT-I T cell; Tfap4-/-; Listeria monocytogenes expressing ovalbumin' vs 'OT-I T cell; wild type; Listeria monocytogenes expressing ovalbumin'cell type, genotype, growth conditionMicroarray analysis of WT and Tfap4-KO CD8 T cells during early activation
Adjusted p-valueLog2-fold change
1.7969 × 10-32.1
Uty'Trem2 knockout, 5XFAD transgenic' vs 'wild type'genotypeTranscription profiling by array of microglia purified from wild type and TREM2 deficient microglia in a mouse model of Alzheimer's disease
Adjusted p-valueLog2-fold change
4.3375 × 10-2-2.1
Uty'Chikungunya virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
3.771 × 10-6-2
Uty'Map3k1C338A,I340A' vs 'wild type genotype'genotypeTranscription profiling by array of embryonic stem cells from mutant Map3k1 mice in comparison to control EL14 cells to investigate molecular mechanisms regulating MAPK signaling in embryonic stem cells
Adjusted p-valueLog2-fold change
5.9228 × 10-4-2
Uty'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
3.8851 × 10-3-2
Uty'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
3.3375 × 10-22
Uty'granulocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
9.0332 × 10-7-1.9
Uty'FVBNCr; RML infected' at '6 week' vs 'FVBNCr; uninfected' at '6 week'strain, time, treatmentTranscription profiling of mouse brain infected with prions in eight mouse-prion strain combinations in a systems approach to the study of prion disease
Adjusted p-valueLog2-fold change
2.0681 × 10-61.9
Uty'Bach2 knockout' vs 'wild type'genotypeRole and function of Bach2 in BCR-ABL1 driven pre-B ALL
Adjusted p-valueLog2-fold change
5.8778 × 10-51.9
Uty'missense mutation (T2996C) in Mucin 2 (Muc2)' vs 'wild type genotype'genotypeTranscription profiling of mouse intestine in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
Adjusted p-valueLog2-fold change
5.8681 × 10-41.9
Uty'acute oropharyngeal candidiasis in IL-17A knockout mice' vs 'acute oropharyngeal candidiasis in wild type genotype mice'compound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
4.6146 × 10-2-1.9
Uty'Cebpa L/L mutant' vs 'wild type'genotypeTranscription profiling by array of mouse LSK hematopoietic stem cells from Cebpa K/K, K/L, and L/L knock-in mutants
Adjusted p-valueLog2-fold change
2.0993 × 10-41.8
Uty'blocked acetylation on lysine 7 residues of RNA Pol II subunit RPB1' vs 'control'phenotypeTranscription profiling by array of NIH/3T3 fibroblasts with blocked acetylation on lysine 7 residues of RNA Pol II subunit RPB1 C-terminal domain because of lysine to arginine substitutions against wild type controls with normal acetylation
Adjusted p-valueLog2-fold change
7.3671 × 10-351.7
Uty'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
2.9576 × 10-61.7
Uty'R1_Pax4+' at '0 day' vs 'wild type' at '0 day'phenotype, timeTranscription profiling of mouse wild type R1 and cells expressing Pax4 following induction of pacreatic differentitation
Adjusted p-valueLog2-fold change
3.0511 × 10-501.6
Uty'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD8-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
1.2434 × 10-5-1.6
Uty'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.1048 × 10-31.6
Uty'bronchoalveolar adenocarcinoma induced using doxycycline' vs 'normal'diseaseTranscription profiling by array of lung alveolar type II epithelial cells with bronchoalveolar adenocarcinoma
Adjusted p-valueLog2-fold change
3.0626 × 10-31.6
Uty'Hnf4a conditional knockout' vs 'wild type genotype'genotypeTranscription profiling of mouse conditional intestinal epithelial Hnf4Ialpha knockout to investigate the role of HNF4alpha in the adult colon
Adjusted p-valueLog2-fold change
2.1693 × 10-21.6
Uty'megakaryocyte' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
3.0725 × 10-26-1.5
Uty'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
7.2848 × 10-6-1.5
Uty'LDB1 knock-down' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
7.9184 × 10-6-1.5
Uty'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
8.5565 × 10-6-1.5
Uty'trichostatin A and LIF' at '12 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
3.1112 × 10-21-1.4
Uty'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.1348 × 10-6-1.4
Uty'induced neural stem cell' vs 'neural stem cell'cell typeGene expression profile of mouse induced neural stem cells
Adjusted p-valueLog2-fold change
3.2886 × 10-5-1.4
Uty'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.4246 × 10-3-1.4
Uty'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.4119 × 10-8-1.3
Uty'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
7.2537 × 10-51.3
Uty'upf3 knockout' vs 'wild type' in 'testis'cell type, genotypeUPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs
Adjusted p-valueLog2-fold change
4.8322 × 10-2-1.3
Uty'fear conditioning' vs 'none'stimulusGene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage
Adjusted p-valueLog2-fold change
2.0042 × 10-7-1.2
Uty'26 day' vs '0 day'ageGene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26)
Adjusted p-valueLog2-fold change
1.5716 × 10-5-1.2
Uty'trichostatin A and LIF' at '6 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
7.5232 × 10-31.2
Uty'metaphase II oocyte' vs 'germinal vesicle oocyte'cell typeTranscription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming
Adjusted p-valueLog2-fold change
5.7614 × 10-51.1
Uty'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
1.0441 × 10-21.1
Uty'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
4.9399 × 10-21.1
Uty'isotype-control; 150 micrograms' vs 'none' in 'methotrexate; first dose 120 milligram per kilogram; second dose 60 milligram per kilogram; wild type phenotype' at '1 day'compound, phenotype, stimulus, timeRNA-seq of mouse crypts to investigate Rorc gamma t-deficient mice tissue repair compared to wild type controls
Adjusted p-valueLog2-fold change
1.6103 × 10-7-1
Uty'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.3121 × 10-61
Uty'Ngn3-expressing cell' vs 'Ngn3-null cell'cell typeTranscriptional profiling of Ngn3-dependent pancreatic endocrine differentiation at E15.5
Adjusted p-valueLog2-fold change
1.1931 × 10-51
Uty'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.0967 × 10-31
Uty'Btk Slp KO (VH81x transgenic Rag1-/-)' vs 'control'genotypePre-BCR Signaling induce IgK Locus Accessibility by functional redistribution of Enhancer-mediated chromatin Interactions
Adjusted p-valueLog2-fold change
3.8557 × 10-3-1
Uty'Csbm/m/Xpa-/-' vs 'wild type'genotypeTranscription profiling of liver from Csbm/m/Xpa-/- knockout mice to investigate the effect of nucleotide excision repair pathway inactivation
Adjusted p-valueLog2-fold change
1.0389 × 10-2-1
Uty'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
2.0415 × 10-2-1
Uty'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.8674 × 10-2-1
Uty'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
4.7347 × 10-21
Uty'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Synonym
Hydb
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4359256, ILMN_2907351, 5349251, 5336684, 95337_at, 1426598_at, ILMN_2467512, 10608107, 1422247_a_at, 17546797, 5206255, A_55_P2134967, 4335060, 5004025, A_52_P266202, ILMN_2563323
Reactome pathway ID