-8.7 | | ENSMUSG00000076258 | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
8.4 | | ENSMUSG00000076258 | 'extracellular vesicle; non-stimulated culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-8.2 | | ENSMUSG00000076258 | 'upf3 knockout' vs 'wild type' in 'testis' | cell type, genotype | UPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs |
7.6 | | ENSMUSG00000076258 | 'extracellular vesicle; EMT cell culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-7.5 | | ENSMUSG00000076258 | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
5.5 | | ENSMUSG00000076258 | 'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-5.1 | | ENSMUSG00000076258 | 'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha' | genotype, stimulus | RNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment |
4.8 | | ENSMUSG00000076258 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
4.2 | | ENSMUSG00000076258 | 'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
3.7 | | ENSMUSG00000076258 | 'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype' | genotype | Antibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq |
3.7 | | ENSMUSG00000076258 | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
3.5 | | ENSMUSG00000076258 | 'extracellular vesicle; MET cell culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
3.4 | | ENSMUSG00000076258 | 'Reverbαflox/floxAlbCreERT2-' vs 'wild type genotype' | genotype | Antibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq |
3.2 | | ENSMUSG00000076258 | 'actinomycin D; 8 hour' vs 'none' in 'Alb-Cre-ERT2 / Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
3.2 | | ENSMUSG00000076258 | 'actinomycin D; 4 hour' vs 'none' in 'Alb-Cre-ERT2 / Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-3.1 | | ENSMUSG00000076258 | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2-GFP knockin; Egr2-GFP high' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
2.8 | | ENSMUSG00000076258 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-2.8 | | ENSMUSG00000076258 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
2.7 | | ENSMUSG00000076258 | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
2.4 | | ENSMUSG00000076258 | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
2.4 | | ENSMUSG00000076258 | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
2.3 | | ENSMUSG00000076258 | 'cut nerve; 7 day' vs 'none' | injury, protocol, time | Changes in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury |
-2.2 | | ENSMUSG00000076258 | 'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
2 | | ENSMUSG00000076258 | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
1.9 | | ENSMUSG00000076258 | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
-1.9 | | ENSMUSG00000076258 | 'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
1.9 | | ENSMUSG00000076258 | '9V/null' vs 'wild type' in 'saline; lung' | compound, genotype, organism part | Gaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase [RNA-Seq] |
1.9 | | ENSMUSG00000076258 | 'R6/2 transgenic' vs 'wild type' in '8 week; brain cortex' | age, genotype, organism part | Transcription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks. |
1.8 | | ENSMUSG00000076258 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '6 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.8 | | ENSMUSG00000076258 | 'KDM4C knock-down' vs 'wild type genotype' in 'mixed-lineage leukemia' | clinical history, genotype | Targeting epigenetic networks mediated by Prmt1 and Kdm4c in acute myeloid leukemia |
-1.8 | | ENSMUSG00000076258 | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-1.8 | | ENSMUSG00000076258 | 'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
-1.7 | | ENSMUSG00000076258 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
1.7 | | ENSMUSG00000076258 | 'Tumor Necrosis Factor' vs 'none' | stimulus | Transcription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor |
1.7 | | ENSMUSG00000076258 | 'reduced expression of miR-25' vs 'wild type' | phenotype | Transcription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice |
1.7 | | ENSMUSG00000076258 | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'white adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-1.6 | | ENSMUSG00000076258 | "muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP positive" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
-1.6 | | ENSMUSG00000076258 | 'Abcc8-/-' vs 'wild type genotype' in 'high fat; male' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
1.6 | | ENSMUSG00000076258 | 'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
1.6 | | ENSMUSG00000076258 | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.6 | | ENSMUSG00000076258 | 'Abcc8-/-' vs 'wild type genotype' in 'normal; male' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
-1.6 | | ENSMUSG00000076258 | 'Aire knockout' vs 'wild type' in 'cTEC' | genotype, phenotype | Transcription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice |
-1.6 | | ENSMUSG00000076258 | 'Zfp521 knockdown by siRNA' vs 'wild type' at '1 day' | phenotype, time | 3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1 |
-1.6 | | ENSMUSG00000076258 | 'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
-1.5 | | ENSMUSG00000076258 | 'liver-specific Cnot1 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
1.5 | | ENSMUSG00000076258 | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
-1.5 | | ENSMUSG00000076258 | 'Abcc8-/-' vs 'wild type genotype' in 'normal; female' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
1.5 | | ENSMUSG00000076258 | 'lung carcinoma' vs 'normal' in 'lung cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-1.5 | | ENSMUSG00000076258 | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
1.5 | | ENSMUSG00000076258 | 'carboplatin; 30 milligram per kilogram' vs 'none' in '14 week; none' | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
1.5 | | ENSMUSG00000076258 | 'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-1.5 | | ENSMUSG00000076258 | 'Zfp521 knockdown by siRNA' vs 'wild type' at '3 day' | phenotype, time | 3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1 |
-1.4 | | ENSMUSG00000076258 | 'male' vs 'female' in 'A/J' | sex, strain | Transcription profiling by high throughput sequencing of hippocampus from adult males and females of six inbred strains of mice |
1.4 | | ENSMUSG00000076258 | 'ticagrelor; 180 milligram per kilogram per day' vs 'none' | compound | RNA-Seq of the liver of hypercholesterolemic mice treated by either ticagrelor, clopidogrel, or control. |
1.4 | | ENSMUSG00000076258 | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.4 | | ENSMUSG00000076258 | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
-1.4 | | ENSMUSG00000076258 | 'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-1.3 | | ENSMUSG00000076258 | 'Cnot4 knockout' vs 'wild type genotype' | genotype | Strand-specific RNA-seq of somite-staged whole embryos from gene knockout lines comparing homozygous mutant against wild-type from the Mouse Genetics Project/DMDD |
1.3 | | ENSMUSG00000076258 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '14 day' vs 'none' at '6 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.3 | | ENSMUSG00000076258 | '3D culture' vs '2D culture' | growth condition | mRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture |
1.3 | | ENSMUSG00000076258 | 'S-(1,2-dichlorovinyl)-L-cysteine; 15 milligram per kilogram; renal injury; 5 week' vs 'none; normal' | compound, disease, time | Expression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC |
1.3 | | ENSMUSG00000076258 | 'Ts1Rhr; KRASG12D' vs 'wild type genotype' | genotype | RNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D |
-1.3 | | ENSMUSG00000076258 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1.3 | | ENSMUSG00000076258 | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
-1.3 | | ENSMUSG00000076258 | 'Trichuris muris' vs 'control' in 'mesenteric lymph node' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
1.3 | | ENSMUSG00000076258 | 'Mycobacterium tuberculosis H37Rv' vs 'none' | infect | The global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice |
1.2 | | ENSMUSG00000076258 | 'Klf14 Knockout' vs 'wild type genotype' in 'liver' | genotype, organism part | Pilot KOMP knockout mouse strains |
1.2 | | ENSMUSG00000076258 | 'Sik1 knockout; abdominal muscle' vs 'wild type genotype; abdominal muscle' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
-1.2 | | ENSMUSG00000076258 | '1810027O10Rik knockout; abdominal muscle' vs 'wild type genotype; abdominal muscle' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
-1.2 | | ENSMUSG00000076258 | 'CD36 knockout' vs 'wild type genotype' in 'oxidized low density lipoprotein; 25 microgram per milliliter' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
1.2 | | ENSMUSG00000076258 | 'hematopoietic stem cell and hematopoietic multipotent progenitor cell' vs 'common myeloid progenitor' | cell type | Transcription profiling by high throughput sequencing between multipotent hematopoietic stem progenitor cells LS+K) and myeloid committed cells (LS−K) of the mouse bone marrow |
1.2 | | ENSMUSG00000076258 | 'RBPjk null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
1.2 | | ENSMUSG00000076258 | 'Scara3 overexpression' vs 'wild type phenotype' | phenotype | RNA sequencing of Mus musculus T helper cell type 2 with retroviral overexpression of different genes |
1.2 | | ENSMUSG00000076258 | '2'-fucosyllactose supplementation' vs 'control' in '8 weeks post-ileocecal resection' | diet, treatment | Transcriptomic characterization of the impact of 2'-fucosyllactose supplementation on intestinal adaptation following ileocecal resection. |
-1.2 | | ENSMUSG00000076258 | 'LDB1 knock-down' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
1.2 | | ENSMUSG00000076258 | 'fear conditioning' vs 'none' | stimulus | Gene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage |
-1.2 | | ENSMUSG00000076258 | 'Rarb -/-' vs 'wild type genotype' in '4-oxoretinoic acid; 5 micromolar' | compound, genotype | RNA Seq of wildtype and Rarb KO HSCs after 24h of in vitro culture and treatment |
-1.2 | | ENSMUSG00000076258 | 'Influenza A virus' vs 'none' | infect | RNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals |
-1.1 | | ENSMUSG00000076258 | '4-oxoretinoic acid; 5 micromolar' vs 'none' in 'Rarb -/-' | compound, genotype | RNA Seq of wildtype and Rarb KO HSCs after 24h of in vitro culture and treatment |
-1.1 | | ENSMUSG00000076258 | 'Mef2d deletion' vs 'wild type' | phenotype | Whole transcriptome sequencing of mouse regulatory T cells with and without Mef2d, Mef2c, HDAC1, HDAC2 or Dyrk1 deletion |
-1.1 | | ENSMUSG00000076258 | 'HDAC2 deletion' vs 'wild type' | phenotype | Whole transcriptome sequencing of mouse regulatory T cells with and without Mef2d, Mef2c, HDAC1, HDAC2 or Dyrk1 deletion |
1.1 | | ENSMUSG00000076258 | 'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.1 | | ENSMUSG00000076258 | 'epithelium-specific Bcl9; Bcl9l knockout and mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-1.1 | | ENSMUSG00000076258 | '129S1 allele at SNP rs50454566' vs 'wild type genotype' | genotype | RNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene |
-1.1 | | ENSMUSG00000076258 | 'Mettl6 knockout clone G6' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
-1.1 | | ENSMUSG00000076258 | 'K14-Cre-ERT2 / CK1α fl/fl; 4-hydroxytamoxifen; none; 14 day' vs 'K14-Cre-ERT2; none; none' | genotype, irradiate, time | Ablation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin |
-1.1 | | ENSMUSG00000076258 | 'poly(I:C)' vs 'none' | stimulus | 3’-Seq of ex vivo isolated mouse multipotent steady state hematopoietic stem cells (sHSC) and proliferating HSCs |
1.1 | | ENSMUSG00000076258 | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
-1.1 | | ENSMUSG00000076258 | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-1.1 | | ENSMUSG00000076258 | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
1 | | ENSMUSG00000076258 | 'embryo transfer' vs 'no embryo transfer' | stimulus | RNA-seq of whole mouse placentas at E10.5 comparing C57Bl/6 male conceptuses that had undergone blastocyst transfer to non-transferred C57Bl/6 male conceptuses |
-1 | | ENSMUSG00000076258 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1 | | ENSMUSG00000076258 | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
1 | | ENSMUSG00000076258 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
-1 | | ENSMUSG00000076258 | 'Elp3fl/fl Trp53fl/fl vav-iCreT/+' vs 'Elp3fl/fl vav-iCreT/+' in 'myeloid lineage restricted progenitor cell' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-1 | | ENSMUSG00000076258 | 'high fat' vs 'normal' in 'wild type genotype; female' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
-1 | | ENSMUSG00000076258 | 'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector' | genotype | RNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice |
1 | | ENSMUSG00000076258 | 'injected with sperm-derived RNA fragments from mice subjected to early life stress (MSUS)' vs 'injected with sperm-derived RNA fragments from control non-stressed mice' | stimulus | Zygotic expression after parental early life stress |
1 | | ENSMUSG00000076258 | 'S-(1,2-dichlorovinyl)-L-cysteine; 15 milligram per kilogram; renal injury; 1 week' vs 'none; normal' | compound, disease, time | Expression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC |
1 | | ENSMUSG00000076258 | 'Il10-/-' vs 'wild type genotype' in 'none' | compound, genotype | RNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion |
1 | | ENSMUSG00000076258 | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-1 | | ENSMUSG00000076258 | 'imiglucerase' vs 'saline' in '9V/null; lung' | compound, genotype, organism part | Gaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase [RNA-Seq] |
1 | | ENSMUSG00000076258 | 'Sall4 -/-' vs 'wild type genotype' | genotype | RNA-Seq of mouse embryonic stem cells in response to changes in Sall4 |