11 | | Ighg3 | 'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
9.6 | | Ighg3 | 'CpG; 6 hour' vs 'none; 0 hour' in 'none' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-9.4 | | Ighg3 | 'clear cell sarcoma; Rosa26CreER' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
9 | | Ighg3 | 'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-8.1 | | Ighg3 | 'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
7.9 | | Ighg3 | '70 week' vs '6 week' in 'none; none; | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
-7.5 | | Ighg3 | 'acute myeloid leukemia' vs 'myeloproliferative disorder' | disease | Transcription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm |
-6.6 | | Ighg3 | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
6.4 | | Ighg3 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-5.8 | | Ighg3 | "muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP positive" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
5.8 | | Ighg3 | 'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
-4.8 | | Ighg3 | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
4.7 | | Ighg3 | 'Plasmodium chabaudi infection' vs 'no infection' in 'vaccination' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
4.6 | | Ighg3 | 'CD36 knockout' vs 'wild type genotype' in 'oxidized low density lipoprotein; 25 microgram per milliliter' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
4.3 | | Ighg3 | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
4.3 | | Ighg3 | 'Trypanosoma brucei STIB247' vs 'uninfected' | infect | Transcription profiling by array of spleens from mice infected with different Trypanosoma brucei strains |
4.3 | | Ighg3 | 'Trypanosoma brucei TREU927' vs 'uninfected' | infect | Transcription profiling by array of spleens from mice infected with different Trypanosoma brucei strains |
4.3 | | Ighg3 | '110 week' vs '8 week' | age | Transcription profiling by array of CD11C+ splenic dendritic cells from young (8 weeks) and old (110 weeks) mice treated with Poly I:C for 4 hours |
-4.2 | | Ighg3 | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
4 | | Ighg3 | '14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-3.7 | | Ighg3 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
3.7 | | Ighg3 | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-3.7 | | Ighg3 | 'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha' | genotype, stimulus | RNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment |
3.6 | | Ighg3 | '14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized male' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
3.6 | | Ighg3 | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
3.5 | | Ighg3 | '7 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
3.5 | | Ighg3 | '14 days P. chabaudi infected' vs 'uninfected' in 'intact female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
3.4 | | Ighg3 | '7 days P. chabaudi infected' vs 'uninfected' in 'intact male' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-3.3 | | Ighg3 | 'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-3.3 | | Ighg3 | 'Dicer knock out' vs 'wild type' | genotype | Transcription profiling by array of mouse Dicer-deficient ooctyes |
3.3 | | Ighg3 | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-3.3 | | Ighg3 | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
3.2 | | Ighg3 | 'Influenza A virus' vs 'none' | infect | RNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals |
3.2 | | Ighg3 | '14 days P. chabaudi infected' vs 'uninfected' in 'intact male' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-3.1 | | Ighg3 | 'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar' | compound, genotype | Overexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment |
2.9 | | Ighg3 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.8 | | Ighg3 | 'Mycobacterium tuberculosis H37Rv' vs 'none' | infect | The global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice |
-2.7 | | Ighg3 | 'Zbtb10 knockdown' vs 'control' at '6 hour' | genotype, time | RNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+) |
2.7 | | Ighg3 | 'Tfc knockout; normal' vs 'control' | disease, genotype | Gene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor. |
-2.5 | | Ighg3 | 'Fn14 knockout' vs 'wild type' in 'none' | compound, genotype | Chronic TNBS Colitis in the FN14 KO Mouse |
2.4 | | Ighg3 | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
2.3 | | Ighg3 | 'Follicular B cell' vs 'Pre-B cell' in 'wild type genotype; MHC II-positive' | cell type, genotype, phenotype | Effect of MHC II expression in pro-B cells: Pre-B cells and follicular B cells from wild-type and MHC II conditional mice |
2.3 | | Ighg3 | 'Aire knockout' vs 'wild type' in 'cTEC' | genotype, phenotype | Transcription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice |
-2.3 | | Ighg3 | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
2.3 | | Ighg3 | 'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
2.2 | | Ighg3 | 'Stella knockout' vs 'wild type genotype' in 'oocyte' | developmental stage, genotype | Transcription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development |
2.2 | | Ighg3 | '7 days P. chabaudi infected' vs 'uninfected' in 'intact female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
2.2 | | Ighg3 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM020 - Infection with SARS MA15 of C57BL/6J mice and KEPI (ppp1r14c) knockouts |
2.2 | | Ighg3 | 'lung carcinoma' vs 'normal' in 'lung cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-2.1 | | Ighg3 | "YFP positive" vs "YFP negative" in "lamina propria of small intestine" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
-2.1 | | Ighg3 | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
2.1 | | Ighg3 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
2 | | Ighg3 | '70 days of tuberculosis' vs 'uninfected' | disease, time | Transcription profiling by array of lungs from mice infected with tuberculosis |
-2 | | Ighg3 | 'epithelium-specific mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
2 | | Ighg3 | 'resiquimod; 100 microgram' vs 'none' in 'ovalbumin; A/J' | compound, stimulus, strain | Transcription profiling of mouse model of asthma reveals the effects of resiquimod treatment on the asthma transcriptome |
-1.9 | | Ighg3 | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
-1.9 | | Ighg3 | 'renin-expression' vs 'control' | phenotype | Expression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein. |
1.9 | | Ighg3 | 'CD21hiCD24hi' vs 'CD21intCD24int' in 'wild type genotype' | genotype, phenotype | Transcription profiling by array to investigate how Aryl hydrocarbon receptor governs a transcriptional programme that determines regulatory B cell differentiation and function |
-1.9 | | Ighg3 | 'Er1F/-' vs 'wild type genotype' | genotype | RNA-Seq profiling of ERCC1-XPF DNA repair defect (Er1F/-) versus wild type (Er1F/+) macrophages |
-1.9 | | Ighg3 | 'Zbtb10 knockdown' vs 'control' at '2 hour' | genotype, time | RNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+) |
1.9 | | Ighg3 | 'Hnf4a-pKO;Hnf1aHET double mutant' vs 'wild type genotype' | genotype | Transcription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice |
-1.8 | | Ighg3 | 'bronchoalveolar adenocarcinoma induced using doxycycline' vs 'normal' | disease | Transcription profiling by array of lung alveolar type II epithelial cells with bronchoalveolar adenocarcinoma |
1.8 | | Ighg3 | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '7 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
1.8 | | Ighg3 | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'white adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1.7 | | Ighg3 | 'CD36 knockout' vs 'wild type genotype' in 'none' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
1.6 | | Ighg3 | '30 days of tuberculosis' vs 'uninfected' | disease, time | Transcription profiling by array of lungs from mice infected with tuberculosis |
-1.6 | | Ighg3 | 'Fn14 knockout' vs 'wild type' in 'trinitrobenzene sulfonic acid' | compound, genotype | Chronic TNBS Colitis in the FN14 KO Mouse |
1.6 | | Ighg3 | "98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young" | age, phenotype | RNAseq of whole ovarian follicles from young and old mice. |
-1.6 | | Ighg3 | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
1.5 | | Ighg3 | 'HDM allergen; IL-13 knockout' vs 'PBS control; IL-13 knockout' on 'Affymetrix MOE430A Array' | compound, genotype | Transcription profiling of wild type and IL13 knock out mice treated with allergen vs. control to investigate the IL13 role in allergic asthma |
1.5 | | Ighg3 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM015 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1a/1b knockouts |
-1.5 | | Ighg3 | 'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
1.5 | | Ighg3 | 'Influenza A virus' vs 'mock' in 'IgG1' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
-1.5 | | Ighg3 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.5 | | Ighg3 | 'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-1.4 | | Ighg3 | 'Aicda knockout' vs 'wild type' in 'activated B cell' | cell type, genotype | Transcription profiling by high throughput sequencing of B cells from activation induced cytidine deaminase (AID) deficient mice |
-1.4 | | Ighg3 | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2-GFP knockin; Egr2-GFP high' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
1.4 | | Ighg3 | 'SMRT shRNA' vs 'none' in 'CpG' at '6 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
1.4 | | Ighg3 | 'IL-10 egfp/egfp' vs 'wild type genotype' in 'CD21hiCD24hi' | genotype, phenotype | Transcription profiling by array to investigate how Aryl hydrocarbon receptor governs a transcriptional programme that determines regulatory B cell differentiation and function |
1.4 | | Ighg3 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.4 | | Ighg3 | 'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1.3 | | Ighg3 | 'SARS coronavirus MA15; 10^2 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.3 | | Ighg3 | 'NOD' vs 'C57BL/6' in 'PBS stimulation' at '18 hour' | strain, time, treatment | Expression data from NOD and C57BL/6 mouse pancreas CD8α- Dendritic Cells (DCs) under steady-state and after in-vitro LPS stimulation |
-1.3 | | Ighg3 | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1.2 | | Ighg3 | '130 week' vs '13 week' in 'lung' | age, organism part | Transcription profiling by array of liver, lung, spleen and kidney from young and old mice. |
1.1 | | Ighg3 | 'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 70 day' vs 'control; D2.B6-Chr7 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.1 | | Ighg3 | 'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.1 | | Ighg3 | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
1.1 | | Ighg3 | 'Stella maternal / zygotic knockout' vs 'wild type genotype' in '1-cell embryo' | developmental stage, genotype | Transcription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development |
1.1 | | Ighg3 | 'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |
1 | | Ighg3 | 'Aicda knockout' vs 'wild type' in 'naive B cell' | cell type, genotype | Transcription profiling by high throughput sequencing of B cells from activation induced cytidine deaminase (AID) deficient mice |
1 | | Ighg3 | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'wild type' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
1 | | Ighg3 | 'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
-1 | | Ighg3 | 'Nix knock out' vs 'wild type' | genotype | Transcription profiling by array of spleens from mice with Nix knocked out. |
1 | | Ighg3 | 'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 15 days post-exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
-1 | | Ighg3 | 'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized' | genotype, treatment | Transcription profiling by high throughput sequencing of uterine-specific Tsc2-null mice |
-1 | | Ighg3 | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |