-5 | | Gm15675 | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-4.2 | | Gm15675 | '21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
4.2 | | Gm15675 | 'Irx3 knockout' vs 'control' at '7 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
-4 | | Gm15675 | "muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP negative" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
-3.9 | | Gm15675 | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-3.7 | | Gm15675 | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
3.3 | | Gm15675 | 'interleukin-13 (Mus musculus); 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
3.3 | | Gm15675 | 'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte' | cell type, compound, genotype | Transcription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin |
3.3 | | Gm15675 | 'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
-3.1 | | Gm15675 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
2.9 | | Gm15675 | 'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-2.7 | | Gm15675 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
-2.5 | | Gm15675 | 'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
2.5 | | Gm15675 | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
2.5 | | Gm15675 | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-2.5 | | Gm15675 | '21 percent oxygen, 37 degree Celsius, no serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
2.5 | | Gm15675 | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
2.4 | | Gm15675 | 'Nippostrongylus brasiliensis' vs 'none' | infect | RNAseq of small intestinal epithelium extracted from mice infected with Nippostrongylus brasiliensis |
-2.4 | | Gm15675 | 'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
2.4 | | Gm15675 | 'reduced expression of miR-25' vs 'wild type' | phenotype | Transcription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice |
2.3 | | Gm15675 | 'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
-2.3 | | Gm15675 | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-2.3 | | Gm15675 | 'carotid body' vs 'adrenal medulla' | organism part | Expression profile of mouse carotid body and adrenal medulla [RNA-Seq] |
-2.2 | | Gm15675 | 'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-2.2 | | Gm15675 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
2.2 | | Gm15675 | 'Gata6 knockout' vs 'wild type' | phenotype | Global gene expression in the adult Gata6 null mouse pancreas |
2.1 | | Gm15675 | 'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
2 | | Gm15675 | 'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized' | genotype, treatment | Transcription profiling by high throughput sequencing of uterine-specific Tsc2-null mice |
-2 | | Gm15675 | 'colitis' at '19 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-2 | | Gm15675 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
1.9 | | Gm15675 | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
1.8 | | Gm15675 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-1.8 | | Gm15675 | 'cut nerve; 7 day' vs 'none' | injury, protocol, time | Changes in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury |
-1.8 | | Gm15675 | 'p60 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA' | RNA interference | RNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells |
1.8 | | Gm15675 | '70 week' vs '6 week' in 'none; none; | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
-1.8 | | Gm15675 | 'Yersinia pestis' vs 'control' in 'neutrophil' | cell type, infect, sampling site | Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague |
1.7 | | Gm15675 | 'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |
-1.7 | | Gm15675 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.7 | | Gm15675 | 'lung carcinoma' vs 'normal' in 'lung cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
1.7 | | Gm15675 | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1.6 | | Gm15675 | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2; Il22-/-' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
-1.5 | | Gm15675 | 'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.5 | | Gm15675 | 'colitis' at '12 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-1.5 | | Gm15675 | 'actinomycin D; 8 hour' vs 'none' in 'Alb-Cre-ERT2 / Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
1.5 | | Gm15675 | 'anti-mPDL1; anti-mCTLA4; 10 milligram per kilogram' vs 'none' at '7 day' | compound, time | RNAseq of tumor samples from CT26 syngeneic mouse treated with a PD-L1 and CTLA-4 immunotherapy combination |
-1.5 | | Gm15675 | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
1.5 | | Gm15675 | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
1.5 | | Gm15675 | 'Influenza A virus' vs 'none' | infect | RNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals |
1.5 | | Gm15675 | 'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector' | genotype | RNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice |
-1.4 | | Gm15675 | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
1.4 | | Gm15675 | 'PH3 homozygous knockout' vs 'wild type phenotype' | phenotype | PHF3 binds RNA polymerase II via the SPOC domain and regulates transcription of neuronal genes - Mouse Embryonic Stem Cell RNAseq |
1.4 | | Gm15675 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1.4 | | Gm15675 | 'LDB1 knock-down' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
-1.3 | | Gm15675 | 'interferon gamma; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
1.3 | | Gm15675 | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1.3 | | Gm15675 | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
-1.3 | | Gm15675 | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
1.3 | | Gm15675 | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1.2 | | Gm15675 | 'Klf3-/-' vs 'wild type' | genotype | RNA-Seq analysis of KLF3 knockout E14.5 TER119+ (erythroid) murine fetal liver cells |
-1.2 | | Gm15675 | 'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
1.2 | | Gm15675 | 'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1.2 | | Gm15675 | '129S1 allele at SNP rs50454566' vs 'wild type genotype' | genotype | RNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene |
-1.1 | | Gm15675 | 'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens |
-1.1 | | Gm15675 | 'Ts1Rhr; KRASG12D' vs 'wild type genotype' | genotype | RNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D |
-1.1 | | Gm15675 | 'KRASG12D' vs 'wild type genotype' | genotype | RNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D |
1.1 | | Gm15675 | 'intestinal smooth muscle culture supernatant' vs 'none' in 'organoid culture without Noggin (ER medium)' | growth condition, stimulus | RNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant |
1.1 | | Gm15675 | 'Tumor Necrosis Factor' vs 'none' | stimulus | Transcription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor |
1.1 | | Gm15675 | 'Mettl6 knockout clone D1' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
-1 | | Gm15675 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Gm15675 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Gm15675 | 'RBM20 antisense oligonucleotide' vs 'none' in 'wild type genotype' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |
-1 | | Gm15675 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Gm15675 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Gm15675 | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2-GFP knockin; Egr2-GFP high' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
1 | | Gm15675 | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1 | | Gm15675 | '9V/null' vs 'wild type' in 'saline; spleen' | compound, genotype, organism part | Gaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase [RNA-Seq] |
1 | | Gm15675 | 'dorsal+ventral thalamus' at 'rheumatoid arthritis model expressing hsTNFɑ' vs 'wild type' | disease, organism part, phenotype | Regional CNS immune fingerprint in chronic peripheral inflammation |
1 | | Gm15675 | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1 | | Gm15675 | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |