ENSMUSG00000090272 (Mndal)

mus musculus

myeloid nuclear differentiation antigen like

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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3
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
9.5448 × 10-18-7.5
Mndal'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
8.0543 × 10-42-6.4
Mndal'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
9.3964 × 10-956.2
Mndal'interleukin-28A; 1000 nanogram per milliliter' vs 'none'compoundTranscription profiling by high throughput sequencing of murine small intestinal epithelial cells stimulated with interleukin-28A
Adjusted p-valueLog2-fold change
8.3711 × 10-65.9
Mndal'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.823 × 10-6-5.7
Mndal'B.D(Chr5)' vs 'C57BL/6'strainGene expression in Lineage negative bone marrow cells of C57B/L6 and B.D(Chr5) mice
Adjusted p-valueLog2-fold change
3.1502 × 10-75.5
Mndal'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
4.5532 × 10-55.3
Mndal'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
5.111 × 10-594.5
Mndal'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.0204 × 10-284.5
Mndal'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
8.8796 × 10-5-4.4
Mndal'TLR4 mutant' vs 'wild type genotype' in 'CCl4 and diethylnitrosamine'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
6.1342 × 10-554.3
Mndal'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.5455 × 10-224
Mndal'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
3.7814 × 10-174
Mndal'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
3.1048 × 10-134
Mndal'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.6149 × 10-413.9
Mndal'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.835 × 10-113.9
Mndal'Chikungunya virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
7.6133 × 10-603.8
Mndal'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.199 × 10-23.8
Mndal'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.1346 × 10-213.7
Mndal'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.1147 × 10-133.7
Mndal'West Nile virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
6.0504 × 10-963.6
Mndal'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
6.0881 × 10-1683.5
Mndal'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.5402 × 10-443.5
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.6512 × 10-8-3.5
Mndal'MEF; transduced with MyoD lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
9.9201 × 10-83.5
Mndal'Foxd3 knockout' vs 'control'phenotypeExpression data from embryonic stem cells differentiation
Adjusted p-valueLog2-fold change
5.462 × 10-53.4
Mndal'9 day' vs '0 day'timeTranscription profiling by array of mineralising murine vascular smooth muscle cell cultures over a nine day culture period to identify new regulators of vascular mineralization
Adjusted p-valueLog2-fold change
6.7079 × 10-43.4
Mndal'MOG35-55' vs 'none' at '20 day'compound, timeTranscriptomic profiling in the animal model of multiple sclerosis
Adjusted p-valueLog2-fold change
1.3641 × 10-263.3
Mndal'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
4.4827 × 10-24-3.3
Mndal'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
2.5255 × 10-3-3.3
Mndal'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.5544 × 10-263.2
Mndal'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.3448 × 10-193.2
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.5534 × 10-53.2
Mndal'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
3.8454 × 10-7-3.1
Mndal'pkd1 knockout' vs 'wild type' in 'presence of fluid flow'genotype, stimulusTranscription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow
Adjusted p-valueLog2-fold change
1.7728 × 10-33.1
Mndal'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
7.3882 × 10-223
Mndal'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.4623 × 10-193
Mndal'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.06 × 10-153
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.8611 × 10-83
Mndal'West Nile virus; early stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
5.6141 × 10-83
Mndal'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
3.9817 × 10-6-3
Mndal'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
4.7084 × 10-2972.9
Mndal'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
7.2384 × 10-134-2.9
Mndal'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
8.6124 × 10-82.9
Mndal'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
9.5881 × 10-82.9
Mndal'dinitrofluorobenzene' vs 'control' in 'Cnr1 -/- /Cnr2 -/-'compound, genotypeTranscription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity
Adjusted p-valueLog2-fold change
3.3206 × 10-72.9
Mndal'15 day' vs '3 day'timeTranscription profiling time series of mouse embryonic chondrocyte differentiation
Adjusted p-valueLog2-fold change
5.9697 × 10-72.9
Mndal'Chikungunya virus; late stage encephalitis' vs 'early stage encephalitis'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
1.737 × 10-62.9
Mndal'dinitrofluorobenzene' vs 'control' in 'wild type'compound, genotypeTranscription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity
Adjusted p-valueLog2-fold change
1.0258 × 10-392.8
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.1147 × 10-122.8
Mndal'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
2.7485 × 10-92.8
Mndal'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
7.4855 × 10-92.8
Mndal'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.8754 × 10-72.8
Mndal'interleukin-3 and interleukin-33' vs 'interleukin-3'growth conditionStem cell factor programs the mast cell activation phenotype
Adjusted p-valueLog2-fold change
9.8344 × 10-4-2.8
Mndal'pkd1 knockout' vs 'wild type' in 'absence of fluid flow'genotype, stimulusTranscription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow
Adjusted p-valueLog2-fold change
1.373 × 10-32.8
Mndal'SARS coronavirus MA15 E protein mutant Δ5' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
7.1466 × 10-672.7
Mndal'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
1.6698 × 10-652.7
Mndal'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
1.7712 × 10-18-2.7
Mndal'Zbtb10 knockdown' vs 'control' at '2 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
3.7923 × 10-72.7
Mndal'chronic pancreatitis' vs 'control'diseasePancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
Adjusted p-valueLog2-fold change
1.3827 × 10-22.7
Mndal'ciliary neurotrophic factor' vs 'vehicle' at '1 day' on 'Affymetrix 430 2.0 Array'compound, timeGene expression profile of glial cells after treatment with ciliary neurotrophic factor
Adjusted p-valueLog2-fold change
1.9996 × 10-2-2.7
Mndal'RA-treated' vs 'control' in 'Hepatic RXR_alpha-Knockout'genotype, treatmentGene expression data of untreated and RA-treated wild type and RXRα-deficient mice liver
Adjusted p-valueLog2-fold change
3.9511 × 10-22.7
Mndal'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
3.0379 × 10-82.6
Mndal'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.7792 × 10-62.6
Mndal'lipopolysaccharide; 100 nanogram per milliliter and interferon gamma 20 nanogram per milliliter' vs 'none'stimulusTranscriptional profiling in macrophages in stimulated and unstimulated conditions.
Adjusted p-valueLog2-fold change
8.4168 × 10-6-2.6
Mndal'Chromogranin A knockout' vs 'wild type genotype'genotypeLiver gene expression from chromogranin A knockout mice (Mahapatra et al. 2005) vs. wild-type mice
Adjusted p-valueLog2-fold change
3.3528 × 10-22.6
Mndal'liver-specific Pit1 knockout' vs 'wild type genotype' in 'regular chow diet'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
7.8879 × 10-822.5
Mndal'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.8223 × 10-702.5
Mndal'dexamethasone; 100 nanomolar; interferon gamma' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
5.5971 × 10-152.5
Mndal'SARS coronavirus MA15; 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.3236 × 10-152.5
Mndal'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
6.8454 × 10-42.5
Mndal'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
6.9039 × 10-42.5
Mndal'SARS coronavirus MA15 E protein mutant Δ3' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
7.6307 × 10-752.4
Mndal'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
6.0307 × 10-222.4
Mndal'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
4.8836 × 10-102.4
Mndal'Kit ligand; wasp knockout' vs 'Kit ligand; wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
2.5546 × 10-82.4
Mndal'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
7.0105 × 10-72.4
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
7.8454 × 10-7-2.4
Mndal'inhibition of BRD4 with JQ1' vs 'DMSO'treatmentExpression Data For BRD4 Inhibition
Adjusted p-valueLog2-fold change
4.5473 × 10-652.3
Mndal'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
7.2017 × 10-302.3
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.1083 × 10-252.3
Mndal'Influenza A virus' vs 'none'infectRNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals
Adjusted p-valueLog2-fold change
3.3055 × 10-222.3
Mndal'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.3132 × 10-172.3
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.4558 × 10-13-2.3
Mndal'Zbtb10 knockdown' vs 'control' at '6 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
4.6998 × 10-102.3
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.3396 × 10-82.3
Mndal'none; wasp knockout' vs 'none; wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
2.1207 × 10-6-2.3
Mndal'proliferating progenitor' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
3.6477 × 10-62.3
Mndal'12 day' vs '3 day'timeTranscription profiling time series of mouse embryonic chondrocyte differentiation
Adjusted p-valueLog2-fold change
4.4539 × 10-62.3
Mndal'interferon alpha' vs 'none'compoundType I and II Interferon-Stimulated Genes in Murine Primary Bone Marrow Macrophages
Adjusted p-valueLog2-fold change
1.8528 × 10-4-2.3
Mndal'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
1.9722 × 10-542.2
Mndal'interferon gamma' vs 'none' in 'dexamethasone; 100 nanomolar'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
1.8471 × 10-38-2.2
Mndal'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
2.8852 × 10-112.2
Mndal'Trichuris muris' vs 'control' in 'non wormy; caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.2086 × 10-8-2.2
Mndal'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.3859 × 10-7-2.2
Mndal'Hmox1 homozygous knockout' vs 'wild type genotype'genotypeGlobal transcriptomic profiles of blood monocytes from Hmox1 homozygous knockout mice compared to wild type controls following Mtb infection
Adjusted p-valueLog2-fold change
5.2835 × 10-42.2
Mndal'SARS coronavirus MA15' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
9.896 × 10-32.2
Mndal'SARS coronavirus MA15 lacking full-length E protein' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
2.4865 × 10-22.2
Mndal'Hnf1a knock out' vs 'wild type'genotypeTranscription profiling of pancreatic islets from Hnf1a-deficient and wild type mice
Adjusted p-valueLog2-fold change
3.0536 × 10-22.2
Mndal'Usp18 knockout' vs 'wild type'genotypeMicroarray analysis to evaluate the function of USP18 in the mouse CNS
Adjusted p-valueLog2-fold change
3.3754 × 10-22.2
Mndal'H1N1 influenza A' at '5 day' vs 'none' at '1 day'infect, timeTranscription profiling of pneumonia lung tissue of H1N1 influenza infected mice
Adjusted p-valueLog2-fold change
8.9115 × 10-1022.1
Mndal'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
8.2345 × 10-40-2.1
Mndal'Cd1d homozyous knockout' vs 'wild type genotype' in 'α-GalCer; 2 microgram'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
7.1596 × 10-272.1
Mndal'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
1.035 × 10-132.1
Mndal'interferon gamma' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
1.3654 × 10-7-2.1
Mndal'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.1495 × 10-72.1
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.3708 × 10-52.1
Mndal'AZD7507; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.012 × 10-32.1
Mndal'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
1.245 × 10-32.1
Mndal'UV' vs 'sham' in 'DMSO' at '6 hour'irradiate, timeTranscription profiling by array of mouse dorsal skin exposed to UV radiation vs controls in mice treated with DMSO or selective tyrosine kinase inhibitor AG825
Adjusted p-valueLog2-fold change
4.5993 × 10-3-2.1
Mndal'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
4.8593 × 10-32.1
Mndal'Gata6 knockout' vs 'wild type'phenotypeGlobal gene expression in the adult Gata6 null mouse pancreas
Adjusted p-valueLog2-fold change
1.3964 × 10-762
Mndal'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
5.1416 × 10-392
Mndal'SMRT shRNA' vs 'none' in 'CpG' at '6 hour'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
4.3254 × 10-382
Mndal'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
3.2432 × 10-362
Mndal'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
1.4907 × 10-28-2
Mndal'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
6.1954 × 10-15-2
Mndal'conventional dendritic cell; Ifnar1 knock out; specific pathogen free' vs 'conventional dendritic cell; wild type genotype; specific pathogen free'cell type, genotype, growth conditionRNA sequencing of primary isolated unstimulated murine splenic DC1 and DC2 from specific pathogen free (SPF), Germ free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice
Adjusted p-valueLog2-fold change
1.3836 × 10-112
Mndal'interferon gamma' vs 'dexamethasone; 100 nanomolar'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
2.5408 × 10-5-2
Mndal'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
1.1307 × 10-32
Mndal'FLT3-ITD Y842F mutant' vs 'FLT3-ITD'genotypeTyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD
Adjusted p-valueLog2-fold change
2.2616 × 10-32
Mndal'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal'diseaseTranscription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma
Adjusted p-valueLog2-fold change
3.2686 × 10-32
Mndal'osteoblast culture 9 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
6.2717 × 10-32
Mndal'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
3.1961 × 10-2-2
Mndal'hypobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to hypobaric hypoxia at Mt. Everest in vivo.
Adjusted p-valueLog2-fold change
3.696 × 10-22
Mndal'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Adjusted p-valueLog2-fold change
1.2897 × 10-981.9
Mndal'Debaryomyces hansenii' at '24 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
1.4501 × 10-15-1.9
Mndal'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.9614 × 10-131.9
Mndal'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.3362 × 10-61.9
Mndal'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
4.4548 × 10-41.9
Mndal'MOG35-55' vs 'none' at '40 day'compound, timeTranscriptomic profiling in the animal model of multiple sclerosis
Adjusted p-valueLog2-fold change
4.4164 × 10-3-1.9
Mndal'AZD5069; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
7.3282 × 10-281.8
Mndal'poly(I:C)' vs 'none'stimulus3’-Seq of ex vivo isolated mouse multipotent steady state hematopoietic stem cells (sHSC) and proliferating HSCs
Adjusted p-valueLog2-fold change
1.332 × 10-251.8
Mndal'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector'genotypeRNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice
Adjusted p-valueLog2-fold change
1.5494 × 10-121.8
Mndal'21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
2.3373 × 10-7-1.8
Mndal'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
7.5108 × 10-71.8
Mndal'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.6045 × 10-61.8
Mndal'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
7.9935 × 10-6-1.8
Mndal'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar'compound, genotypeOverexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment
Adjusted p-valueLog2-fold change
1.2088 × 10-51.8
Mndal'Lactobacillus acidophilus NCFM' vs 'control'infectTranscription profiling by array of mouse dendritic cells after infection with Bifidobacterium bifidum and Lactobacillus acidophilus
Adjusted p-valueLog2-fold change
1.0732 × 10-41.8
Mndal'2 day' vs '1 day' in 'influenza A infected C57BL/6J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
2.3769 × 10-4-1.8
Mndal'14 days P. chabaudi infected' vs 'uninfected' in 'intact male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
2.6296 × 10-41.8
Mndal'6 day' vs '0 day'timeTranscription profiling by array of mouse colon tissues under dextran sodium sulphate induction for 2, 4 and 6 days against uninduced controls at day 0
Adjusted p-valueLog2-fold change
3.0221 × 10-3-1.8
Mndal'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
3.9049 × 10-31.8
Mndal'dextran sodium sulfate' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion
Adjusted p-valueLog2-fold change
4.5092 × 10-1481.7
Mndal'Debaryomyces hansenii' at '6 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
1.0589 × 10-211.7
Mndal'lipopolysaccharide' vs 'none' in 'bone marrow; wild type'cell type, compound, genotypeTranscription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice
Adjusted p-valueLog2-fold change
1.9431 × 10-171.7
Mndal'SARS coronavirus MA15; 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.232 × 10-13-1.7
Mndal'plasmacytoid dendritic cell; Ifnar1 knock out; specific pathogen free' vs 'plasmacytoid dendritic cell; wild type genotype; specific pathogen free'cell type, genotype, growth conditionRNA sequencing of primary isolated unstimulated murine splenic DC1 and DC2 from specific pathogen free (SPF), Germ free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice
Adjusted p-valueLog2-fold change
8.6607 × 10-10-1.7
Mndal'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
6.966 × 10-9-1.7
Mndal'epithelium-specific mutant beta-catenin expression' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
1.6874 × 10-7-1.7
Mndal'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.9483 × 10-7-1.7
Mndal'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.1536 × 10-71.7
Mndal'SARS coronavirus MA15; 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.4415 × 10-61.7
Mndal'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
5.1558 × 10-6-1.7
Mndal'MyD88 homozygous knockout' vs 'wild type genotype' in 'TLR9 ligand CpG ODN (1826)'genotype, stimulusTranscription profiling by sequencing of murine MyD88 -/- and MyD88 +/+ mTECs stimulated with a TLR9 ligand
Adjusted p-valueLog2-fold change
6.78 × 10-61.7
Mndal'3 day' vs '1 day' in 'influenza A infected C57BL/6J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
1.7344 × 10-51.7
Mndal'Lactobacillus acidophilus NCFM and Bifidobacterium bifidum Z9' vs 'control'infectTranscription profiling by array of mouse dendritic cells after infection with Bifidobacterium bifidum and Lactobacillus acidophilus
Adjusted p-valueLog2-fold change
2.4607 × 10-5-1.7
Mndal'acute oropharyngeal candidiasis' vs 'healthy' in wild type micecompound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
3.5382 × 10-51.7
Mndal'6 week' vs '0 week'timeTranscription profiling by array of mouse colon tissues with T cell transfer-induced colitis at week 0, 2, 4 and 6 post-transfer
Adjusted p-valueLog2-fold change
7.7944 × 10-4-1.7
Mndal'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; adult'cell type, developmental stageTranscription profiling of mouse adult and fetal T cell progenitors
Adjusted p-valueLog2-fold change
4.8323 × 10-31.7
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NZO/HILtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.9893 × 10-31.7
Mndal'Staphylococcus aureus cutaneous infection' vs 'none' in 'IL-1R knockout'disease, genotypeNeutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice
Adjusted p-valueLog2-fold change
1.0068 × 10-21.7
Mndal'UV' vs 'sham' in 'AG825' at '6 hour'irradiate, timeTranscription profiling by array of mouse dorsal skin exposed to UV radiation vs controls in mice treated with DMSO or selective tyrosine kinase inhibitor AG825
Adjusted p-valueLog2-fold change
1.8148 × 10-101.6
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.1027 × 10-7-1.6
Mndal'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.7188 × 10-71.6
Mndal'Helicobacter hepaticus' vs 'none' in 'wild type phenotype'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
4.3603 × 10-71.6
Mndal'Influenza A virus' vs 'mock' in 'interleukin-22'infect, stimulusTranscription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza
Adjusted p-valueLog2-fold change
4.3629 × 10-7-1.6
Mndal'Gprc5a knockout' vs 'control'genotypeGene expression profile of lung epithelial cells cultured from normal tracheas of Gprc5a knockout and wild-type mice
Adjusted p-valueLog2-fold change
4.9294 × 10-61.6
Mndal'Staphylococcus aureus Sanger476; 4 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.4025 × 10-5-1.6
Mndal'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
1.4373 × 10-5-1.6
Mndal'Men1-null' vs 'wild type'genotypeDifferentially regulated genes in adipocytes derived from Men1-null vs WT mouse embryonic stem cells
Adjusted p-valueLog2-fold change
1.0696 × 10-41.6
Mndal'interferon gamma' vs 'none'compoundType I and II Interferon-Stimulated Genes in Murine Primary Bone Marrow Macrophages
Adjusted p-valueLog2-fold change
1.3655 × 10-41.6
Mndal'4 day' vs '1 day' in 'influenza A infected C57BL/6J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
2.1285 × 10-4-1.6
Mndal'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
4.2559 × 10-41.6
Mndal'Staphylococcus aureus Sanger476; 6 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.7198 × 10-3-1.6
Mndal'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; lipopolysaccharide; 10 nanogram per milliliter'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.4046 × 10-21.6
Mndal'FusΔNLS/+' vs 'wild type genotype' at '24 hour'genotype, timeMutant FUS triggers age-dependent synaptic impairment in presymptomatic ALS-FUS mice (RNA-seq part2)
Adjusted p-valueLog2-fold change
4.5656 × 10-2-1.6
Mndal'Cdx2 knockdown' vs 'scramble shRNA' in 'induced hepatocyte'cell type, genotypeDissecting engineered cell types and enhancing cell fate conversion via CellNet
Adjusted p-valueLog2-fold change
4.699 × 10-2-1.6
Mndal'130 week' vs '13 week' in 'spleen'age, organism partTranscription profiling by array of liver, lung, spleen and kidney from young and old mice.
Adjusted p-valueLog2-fold change
1.349 × 10-57-1.5
Mndal'embryo transfer' vs 'no embryo transfer'stimulusRNA-seq of whole mouse placentas at E10.5 comparing C57Bl/6 male conceptuses that had undergone blastocyst transfer to non-transferred C57Bl/6 male conceptuses
Adjusted p-valueLog2-fold change
7.1723 × 10-161.5
Mndal'hematopoietic stem cell and hematopoietic multipotent progenitor cell' vs 'common myeloid progenitor'cell typeTranscription profiling by high throughput sequencing between multipotent hematopoietic stem progenitor cells LS+K) and myeloid committed cells (LS−K) of the mouse bone marrow
Adjusted p-valueLog2-fold change
1.1542 × 10-71.5
Mndal'Escherichia coli O18:K1:H7; 6 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
5.3361 × 10-7-1.5
Mndal'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.7142 × 10-6-1.5
Mndal'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.3455 × 10-6-1.5
Mndal'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.4029 × 10-61.5
Mndal'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.5178 × 10-51.5
Mndal'interferon beta' vs 'none' in 'wild type; uninfected'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
3.1001 × 10-51.5
Mndal'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
3.5232 × 10-5-1.5
Mndal'doxycycline; no induction of Sp1 expression' vs 'none; wild type human Sp1 expression'compound, genotypeTranscription profiling of mouse hematopoietic Baf-3 cells inducibly expressing transcription factor Sp1
Adjusted p-valueLog2-fold change
3.8892 × 10-5-1.5
Mndal'5,9-endoperoxy-cholest-7-en-3β,6α-diol' vs 'vehicle (cyclodextrin)'compound, timeArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
Adjusted p-valueLog2-fold change
8.1904 × 10-5-1.5
Mndal'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
9.1786 × 10-51.5
Mndal'21 percent oxygen, 37 degree Celsius, no serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
3.5481 × 10-41.5
Mndal'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
7.7112 × 10-41.5
Mndal'19BL; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
3.4316 × 10-31.5
Mndal'polarized with E coli lipopolysacharide and INF-gamma' vs 'untreated'compound, treatmentExpression data from polarized macrophages: effect of p53
Adjusted p-valueLog2-fold change
4.2415 × 10-3-1.5
Mndal'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
6.7995 × 10-31.5
Mndal'Tfc knockout; normal' vs 'control'disease, genotypeGene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor.
Adjusted p-valueLog2-fold change
7.8786 × 10-31.5
Mndal'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
1.3852 × 10-21.5
Mndal'Tet2 knockout' vs 'wild type' in 'hematopoietic progenitor cell'cell type, genotypeTranscription profiling by high throughput sequencing of bone marrow stem and progenitor cells from Tet2 depleted mice
Adjusted p-valueLog2-fold change
4.1077 × 10-2-1.5
Mndal'Cbir-flagellin' vs 'none' in 'B6-interleukin 10-/-'stimulus, strainTranscription profiling of bone marrow-derived macrophages from colitis-resistant and colitis-susceptible interleukin-10-deficient strains stimulated with Cbir-flagellin
Adjusted p-valueLog2-fold change
4.4039 × 10-21.5
Mndal'Staphylococcus aureus cutaneous infection' vs 'none' in 'wild type'disease, genotypeNeutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice
Adjusted p-valueLog2-fold change
4.9365 × 10-21.5
Mndal'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
4.4305 × 10-121.4
Mndal'mir181a1/b1 Knockout' vs 'wild type'genotypeMouse CD4+/CD8+ thymocytes from miR-181a1/b1 KO vs WT
Adjusted p-valueLog2-fold change
1.8052 × 10-9-1.4
Mndal'acute myeloid leukemia' vs 'myeloproliferative disorder'diseaseTranscription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm
Adjusted p-valueLog2-fold change
1.0935 × 10-61.4
Mndal'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
1.7575 × 10-5-1.4
Mndal'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
6.4228 × 10-51.4
Mndal'Influenza A virus' vs 'mock' in 'IgG1'infect, stimulusTranscription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza
Adjusted p-valueLog2-fold change
8.6533 × 10-51.4
Mndal'cycloheximide and 100 unit per milliliter interferon alpha' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
3.2708 × 10-41.4
Mndal'4 week' vs '0 week'timeTranscription profiling by array of mouse colon tissues with T cell transfer-induced colitis at week 0, 2, 4 and 6 post-transfer
Adjusted p-valueLog2-fold change
5.5736 × 10-4-1.4
Mndal'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
4.2304 × 10-31.4
Mndal'TLR9 ligand CpG ODN (1826)' vs 'none' in 'wild type genotype'genotype, stimulusTranscription profiling by sequencing of murine MyD88 -/- and MyD88 +/+ mTECs stimulated with a TLR9 ligand
Adjusted p-valueLog2-fold change
1.1065 × 10-21.4
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.5229 × 10-2-1.4
Mndal'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; prostaglandin E2; 1 micromolar'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.5651 × 10-101.3
Mndal'Plasmodium berghei ANKA' at '6 day' vs 'none' at '0 day' in 'none'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
7.9394 × 10-6-1.3
Mndal'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
8.6147 × 10-6-1.3
Mndal'Pcbp2 knockout' vs 'wild type genotype'genotypeTranscription profiling by RNA-seq of fetal liver from poly(C) binding protein 2 (Pcbp2) knockout mice
Adjusted p-valueLog2-fold change
3.3309 × 10-51.3
Mndal'Plasmodium berghei ANKA' at '7 day' vs 'none' at '0 day' in 'none'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
1.3253 × 10-41.3
Mndal'70 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
2.0088 × 10-41.3
Mndal'influenza' vs 'uninfected' in 'wild type'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
2.2131 × 10-41.3
Mndal'Bifidobacterium bifidum Z9' vs 'control'infectTranscription profiling by array of mouse dendritic cells after infection with Bifidobacterium bifidum and Lactobacillus acidophilus
Adjusted p-valueLog2-fold change
2.9024 × 10-4-1.3
Mndal'HDAC2 knockout' vs 'control'genotypeThe acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis
Adjusted p-valueLog2-fold change
1.5662 × 10-3-1.3
Mndal'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
5.4031 × 10-3-1.3
Mndal'neoplasm' vs 'normal tissue adjacent to neoplasm'sampling siteTranscription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa
Adjusted p-valueLog2-fold change
7.8922 × 10-3-1.3
Mndal'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
8.0674 × 10-31.3
Mndal'unilateral ureteral obstruction' vs 'sham' in 'wild type'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
1.0375 × 10-21.3
Mndal'colitis' at '19 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
1.6613 × 10-21.3
Mndal'Alb-Cre;VHLf/f' vs 'Alb-Cre'genotypeTranscription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor
Adjusted p-valueLog2-fold change
2.3625 × 10-21.3
Mndal'Hnf4a-pKO;Hnf1aHET double mutant' vs 'wild type genotype'genotypeTranscription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice
Adjusted p-valueLog2-fold change
2.7231 × 10-21.3
Mndal'12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
4.713 × 10-21.3
Mndal'14M1.4; Leishmania donovani infected' at '12 hour' vs '14M1.4; normal' at '12 hour'cell line, infect, timeTranscription profiling of 3 mouse cell lines infected with Leishmania
Adjusted p-valueLog2-fold change
3.3383 × 10-461.2
Mndal'SARS coronavirus MA15; 4 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.3043 × 10-44-1.2
Mndal'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
2.8826 × 10-17-1.2
Mndal"YFP positive" vs "YFP negative" in "lamina propria of small intestine"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
2.2444 × 10-8-1.2
Mndal'MEF2A knockout' vs 'wild type genotype' in 'Hoxb8-FL; none'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.0191 × 10-71.2
Mndal'Plasmodium berghei' vs 'none' in 'none'compound, infectTranscription profiling by array of mouse blood infected with Plasmodium berghei after treatment with activated charcoal
Adjusted p-valueLog2-fold change
5.5939 × 10-61.2
Mndal'Porphyromonas gingivalis; normal' vs 'normal'infect, phenotypehyperlipidemia impaired innate response
Adjusted p-valueLog2-fold change
6.8269 × 10-61.2
Mndal'Porphyromonas gingivalis; hyperlipidemia' vs 'normal'infect, phenotypehyperlipidemia impaired innate response
Adjusted p-valueLog2-fold change
8.2156 × 10-6-1.2
Mndal'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.3582 × 10-51.2
Mndal'artesunate and chloroquine (at same dosage); 30 milligram per kilogram; Plasmodium berghei ANKA; 7 day' vs 'none; none; 0 day'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
1.9458 × 10-51.2
Mndal'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
2.7559 × 10-5-1.2
Mndal'cholesterol' vs 'vehicle (cyclodextrin)'compound, timeArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
Adjusted p-valueLog2-fold change
4.5431 × 10-5-1.2
Mndal'Trypanosoma brucei STIB247' vs 'uninfected'infectTranscription profiling by array of spleens from mice infected with different Trypanosoma brucei strains
Adjusted p-valueLog2-fold change
1.9004 × 10-41.2
Mndal'Staphylococcus aureus MW2; 2 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.7354 × 10-4-1.2
Mndal'Er1F/-' vs 'wild type genotype'genotypeRNA-Seq profiling of ERCC1-XPF DNA repair defect (Er1F/-) versus wild type (Er1F/+) macrophages
Adjusted p-valueLog2-fold change
4.1288 × 10-41.2
Mndal'cycloheximide and 100 unit per milliliter interferon gamma' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
4.8123 × 10-4-1.2
Mndal'Macrophage of F4/80+, CD11b+, CD11c-+; obese leptin-deficient' vs 'Macrophage of F4/80+, CD11b+, CD11c-+; control'cell type, genotypeExpression data from mouse adipose tissue macrophage
Adjusted p-valueLog2-fold change
8.3514 × 10-4-1.2
Mndal'14 days P. chabaudi infected' vs 'uninfected' in 'intact female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
1.9271 × 10-3-1.2
Mndal'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha'genotype, stimulusRNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment
Adjusted p-valueLog2-fold change
3.4173 × 10-3-1.2
Mndal'Trypanosoma brucei TREU927' vs 'uninfected'infectTranscription profiling by array of spleens from mice infected with different Trypanosoma brucei strains
Adjusted p-valueLog2-fold change
4.5395 × 10-31.2
Mndal'Cnot3 knockout' vs 'wild type'phenotypeRNA-seq of mouse islets from Ins1-cre driven Cnot3 KO and control islets
Adjusted p-valueLog2-fold change
6.7479 × 10-3-1.2
Mndal'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
8.0713 × 10-31.2
Mndal'Ffar3 knockout' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of pancreatic islets isolated from free fatty acid receptor 3 knockout (Ffar3 KO) and wild type (Ffar3 WT) male mice
Adjusted p-valueLog2-fold change
1.1584 × 10-21.2
Mndal'cecal ligation and puncture surgery; PPTA knockout' vs 'cecal ligation and puncture surgery; wild type'clinical treatment, genotypeGene expression profile in lung tissue 8 h after inducing polymicrobial sepsis in preprotachykinin-A (PPTA) knockout mice and wild type
Adjusted p-valueLog2-fold change
1.885 × 10-21.2
Mndal'anti-IL-17A and anti-IL-17F treatment' vs 'no treatment' in 'wild type mice with acute oropharyngeal candidiasis'compound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
3.0483 × 10-2-1.2
Mndal'Id3 knockout' vs 'wild type' in 'Tet+CD24-CD44+NK1.1- Invariant natural killer T'cell type, genotypeEssential functions for ID proteins at multiple checkpoints in natural killer T cell development
Adjusted p-valueLog2-fold change
3.5182 × 10-2-1.2
Mndal'Rb^{lox/lox}; p130^{lox/lox}; p107+/-' vs 'wild type'genotypeTranscription profiling by array of livers from the mouse model of human hepatocellular carcinoma
Adjusted p-valueLog2-fold change
7.6285 × 10-101.1
Mndal'Mycobacterium tuberculosis H37Rv' vs 'none' in 'wild type'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
2.9447 × 10-7-1.1
Mndal'nmf205, Gcn2 double mutant' vs 'wild type'genotypeTranscription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/-
Adjusted p-valueLog2-fold change
6.7947 × 10-7-1.1
Mndal'Kit ligand' vs 'none' in 'wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
4.0653 × 10-6-1.1
Mndal'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1'cell type, growth condition, phenotypeTranscription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture
Adjusted p-valueLog2-fold change
8.4534 × 10-6-1.1
Mndal'interleukin-4; 20 nanogram per milliliter' vs 'none; 'compoundGenome-wide analysis of mouse macrophages stimulated with IL-4 (bone marrow macrophages) (Affymetrix)
Adjusted p-valueLog2-fold change
2.922 × 10-5-1.1
Mndal'epithelium-specific Apc knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
7.6958 × 10-41.1
Mndal'renin-expression' vs 'control'phenotypeExpression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein.
Adjusted p-valueLog2-fold change
1.4038 × 10-31.1
Mndal'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
5.6507 × 10-3-1.1
Mndal'IFNR null' vs 'wild type' in 'influenza infected'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
6.3417 × 10-3-1.1
Mndal'acute oropharyngeal candidiasis wild type mice'; female' vs 'healthy wild type genotype mice'compound, disease, genotype, sexTranscription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis
Adjusted p-valueLog2-fold change
8.0351 × 10-31.1
Mndal'overexpression of miR-142-3p' vs 'control'phenotypeTranscription profiling by array of mouse bone marrow cells transfected with miR 142-3p mimic oligo
Adjusted p-valueLog2-fold change
1.0805 × 10-21.1
Mndal'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
8.4546 × 10-12-1
Mndal'NHD13 mutant' vs 'wild type'genotypeMyelodysplastic syndrome: NUP98-HoxD13 (NHD13) expression effect on hematopoietic stem cells
Adjusted p-valueLog2-fold change
2.2369 × 10-71
Mndal'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
3.2793 × 10-7-1
Mndal'Tumor Necrosis Factor' vs 'none'stimulusTranscription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor
Adjusted p-valueLog2-fold change
5.9326 × 10-71
Mndal'CCl4; 1.6 gram per kilogram' at '96 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
2.9301 × 10-6-1
Mndal'Kit ligand' vs 'none' in 'wasp knockout'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
3.67 × 10-6-1
Mndal'butyrate' vs 'none'compoundHDAC inhibition by TSA and Butyrate In Flt3L-elicited DC
Adjusted p-valueLog2-fold change
2.9127 × 10-41
Mndal'CDK4/6 inhibitor PD 0332991' vs 'vehicle'compoundGene expression profile of mouse breast cancer V720 cells treated with vehicle or PD 0332991
Adjusted p-valueLog2-fold change
5.1615 × 10-4-1
Mndal'heterozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5'developmental stage, genotypeMicroarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels
Adjusted p-valueLog2-fold change
6.5306 × 10-4-1
Mndal'diet restriction' vs 'control'dietLiver mRNA microarray study for mice treated with various diets
Adjusted p-valueLog2-fold change
9.9421 × 10-41
Mndal'10 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
1.1511 × 10-31
Mndal'Chikungunya virus; early stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
1.2182 × 10-31
Mndal'dibenzazapine 10 micromoles per kilogram' vs 'none'compound, doseTranscription profiling by array of pancreatic cells from C57BL/6 mice following dibenzazepine treatment
Adjusted p-valueLog2-fold change
2.4936 × 10-3-1
Mndal'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'conditional UPF2 knockout; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
4.6553 × 10-3-1
Mndal'Cbfb+/MYH11' vs 'control of Cbfb+/MYH11'genotypeTranscription profiling by array of Mus musculus expressing Cbfb-MYH11
Adjusted p-valueLog2-fold change
4.8704 × 10-3-1
Mndal'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
7.0195 × 10-3-1
Mndal'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
7.8158 × 10-31
Mndal'apoE knock-out' vs 'wild type'genotypeTranscription profiling by array of aorta from apoE knock-out mice
Adjusted p-valueLog2-fold change
9.4029 × 10-31
Mndal'transgenic humanSODG93A' vs 'wild type' in 'gastrocnemius'clinical treatment, genotype, organism partGene expression profiling of muscles from transgenic humanSODG93A mice at symptomatic stage
Adjusted p-valueLog2-fold change
1.0463 × 10-21
Mndal'Influenza A virus (A/Scotland/20/1974(H3N2))' vs 'none'infectRNA-seq of mouse colon to investigate how influenza infection leads to intestinal disorders
Adjusted p-valueLog2-fold change
1.1851 × 10-2-1
Mndal'E-FABP knockout' vs 'wild type'genotypeGene expression microarray data of bone marrow derived macrophages using GM-CSF(GM-BMMs) co-cultured with E0771 breast tumor cells
Adjusted p-valueLog2-fold change
1.3164 × 10-2-1
Mndal'perfluorooctanoic acid; 5 milligram per kilogram per day' vs 'none' in 'liver'block, compound, organism partTranscription profiling of lung and liver from low and high dose Perfluorooctanoic Acid exposed fetuses
Adjusted p-valueLog2-fold change
1.4934 × 10-21
Mndal'dorsal+ventral thalamus' at 'rheumatoid arthritis model expressing hsTNFɑ' vs 'wild type'disease, organism part, phenotypeRegional CNS immune fingerprint in chronic peripheral inflammation
Adjusted p-valueLog2-fold change
1.8682 × 10-21
Mndal'12 week' vs '4 week'ageDifferential gene expression in the Lacrimal gland during development and onset of xerostomia in Sjogren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse.
Adjusted p-valueLog2-fold change
2.3504 × 10-21
Mndal'Timp3-/-' vs 'wild type genotype'genotypeTranscription profiling by array of kidneys from diabetic wild type and T3-/- mice
Adjusted p-valueLog2-fold change
2.4254 × 10-2-1
Mndal'Notch 1 and 2 null' vs 'wild type'genotypeQuantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS
Adjusted p-valueLog2-fold change
2.6902 × 10-21
Mndal'K-ras mutant/Wt1-null' vs 'wild type'genotypeTranscription profiling by array of wild type, K-ras mutant, Wt1-null, and double K-ras mutant/Wt1-null mouse embryonic fibroblasts
Adjusted p-valueLog2-fold change
2.8103 × 10-21
Mndal'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.9852 × 10-21
Mndal'liver-specific Gp130 knockout mice [Gp130delta(hepa)]; cecal ligation and puncture' vs 'liver-specific Gp130 knockout mice [Gp130delta(hepa)]; control'genotype, treatmentHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Adjusted p-valueLog2-fold change
3.4686 × 10-21
Mndal'3D culture' vs '2D culture'growth conditionmRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture
Adjusted p-valueLog2-fold change
4.857 × 10-21
Mndal'vimentin deficient' vs 'wild type'genotypeExpression data from bone marrow-derived macrophages