-6.6 | | Gm5547 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-6.4 | | Gm5547 | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-5.5 | | Gm5547 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-5.1 | | Gm5547 | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-4.4 | | Gm5547 | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
3.7 | | Gm5547 | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
3.2 | | Gm5547 | 'colitis' at '19 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-3 | | Gm5547 | 'Tumor Necrosis Factor' vs 'none' | stimulus | Transcription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor |
-2.9 | | Gm5547 | 'acute myeloid leukemia' vs 'myeloproliferative disorder' | disease | Transcription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm |
-2.9 | | Gm5547 | 'Med1 knockout' vs 'wild type' in 'ventral prostate' | genotype, organism part | Changes in gene expression caused by loss of Med1 in the mouse prostate |
2.8 | | Gm5547 | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-2.7 | | Gm5547 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
-2.6 | | Gm5547 | "Evi1-GFP positive" vs "Evi1-GFP negative" | phenotype | Whole genome expression profiling of Evi1-GFP positive and negative murine hematopoietic stem cell sub-populations. |
2.5 | | Gm5547 | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-2.4 | | Gm5547 | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
2.3 | | Gm5547 | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
2.3 | | Gm5547 | 'LDB1 knock-down' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
-2.2 | | Gm5547 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
2.2 | | Gm5547 | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-2.1 | | Gm5547 | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
2 | | Gm5547 | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
-2 | | Gm5547 | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
2 | | Gm5547 | 'KDM4C knock-down' vs 'wild type genotype' in 'mixed-lineage leukemia' | clinical history, genotype | Targeting epigenetic networks mediated by Prmt1 and Kdm4c in acute myeloid leukemia |
-2 | | Gm5547 | 'overexpression of SRC-2' vs 'control' | phenotype | A pivotal role of SRC-2 in Metastatic and Castration Resistant Prostate Cancer |
2 | | Gm5547 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.8 | | Gm5547 | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
-1.8 | | Gm5547 | "muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP positive" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
-1.8 | | Gm5547 | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.8 | | Gm5547 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.8 | | Gm5547 | '70 week' vs '6 week' in 'none; none; | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
1.7 | | Gm5547 | 'Influenza A virus' vs 'mock' in 'interleukin-22' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
1.7 | | Gm5547 | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
-1.7 | | Gm5547 | 'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1.7 | | Gm5547 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.7 | | Gm5547 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.6 | | Gm5547 | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
1.6 | | Gm5547 | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
1.5 | | Gm5547 | 'Mycobacterium tuberculosis H37Rv' vs 'none' | infect | The global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice |
-1.5 | | Gm5547 | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.5 | | Gm5547 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.5 | | Gm5547 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.4 | | Gm5547 | 'Influenza A virus' vs 'mock' in 'IgG1' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
-1.4 | | Gm5547 | 'doxycycline; no induction of Sp1 expression' vs 'none; wild type human Sp1 expression' | compound, genotype | Transcription profiling of mouse hematopoietic Baf-3 cells inducibly expressing transcription factor Sp1 |
1.4 | | Gm5547 | 'ciliary neurotrophic factor' vs 'vehicle' at '1 day' on 'Affymetrix 430 2.0 Array' | compound, time | Gene expression profile of glial cells after treatment with ciliary neurotrophic factor |
-1.3 | | Gm5547 | 'KRASG12D' vs 'wild type genotype' | genotype | RNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D |
-1.3 | | Gm5547 | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.3 | | Gm5547 | 'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1.3 | | Gm5547 | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'classical monocyte' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
1.2 | | Gm5547 | 'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
-1.2 | | Gm5547 | 'polarized with E coli lipopolysacharide and INF-gamma' vs 'untreated' | compound, treatment | Expression data from polarized macrophages: effect of p53 |
-1.2 | | Gm5547 | 'Ts1Rhr; KRASG12D' vs 'wild type genotype' | genotype | RNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D |
1.2 | | Gm5547 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
1.2 | | Gm5547 | 'trinitrobenzene sulfonic acid' vs 'none' in 'wild type' | compound, genotype | Chronic TNBS Colitis in the FN14 KO Mouse |
-1.2 | | Gm5547 | "muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP negative" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
1.2 | | Gm5547 | 'RBM20 antisense oligonucleotide' vs 'none' in 'wild type genotype' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |
1.2 | | Gm5547 | 'chemical hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo. |
-1.2 | | Gm5547 | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Transcription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa |
-1.2 | | Gm5547 | 'Id2_Id3_double knockout' vs 'wild type' in 'CD4+TCRb+CD8– cell; thymus' | cell type, genotype, organism part | Transcription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells |
1.1 | | Gm5547 | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '7 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
1.1 | | Gm5547 | 'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.1 | | Gm5547 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM020 - Infection with SARS MA15 of C57BL/6J mice and KEPI (ppp1r14c) knockouts |
-1.1 | | Gm5547 | 'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.1 | | Gm5547 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.1 | | Gm5547 | 'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
-1.1 | | Gm5547 | 'epithelium-specific mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1 | | Gm5547 | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
1 | | Gm5547 | '6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
-1 | | Gm5547 | 'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
1 | | Gm5547 | 'SARS coronavirus MA15' vs 'none' in 'Tnfrsf1a/1b -/-' at '7 day' | genotype, infect, time | SM015 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1a/1b knockouts |
1 | | Gm5547 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day' | genotype, infect, time | SM015 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1a/1b knockouts |
-1 | | Gm5547 | 'LKB1 knockout; floxed LKB1 with Ins1-Cre' vs 'floxed LKB1 without Ins1-Cre; wild type' | genotype, phenotype | Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice |
1 | | Gm5547 | '30 days of tuberculosis' vs 'uninfected' | disease, time | Transcription profiling by array of lungs from mice infected with tuberculosis |
1 | | Gm5547 | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1 | | Gm5547 | 'adipose tissue specific Trim28 knockout' vs 'wild type genotype' in 'male' | genotype, sex | RNA-seq of gonadal adipose tissue from male and female Trim28-WT and Trim28 adipose specific KO mice |
-1 | | Gm5547 | 'Macrophage of F4/80+, CD11b+, CD11c-+; obese leptin-deficient' vs 'Macrophage of F4/80+, CD11b+, CD11c-+; control' | cell type, genotype | Expression data from mouse adipose tissue macrophage |
1 | | Gm5547 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Gm5547 | 'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |