ENSMUSG00000111118 (Gm6545)

mus musculus

predicted gene 6545

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Mus musculus
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Showing 56 experiments:
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Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermhippocampuslungolfactory bulbskeletal muscle organtracheaaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartintestinal mucosalateral prominence neural epitheliummedial nasal prominencemuscle (biceps femoris)oviductpreoptic areaspleensubventricular zonevesicular glandwhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9
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14 - embryonic day 10.5
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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GENCODE
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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Developing gut
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49 FANTOM5 project - embryonic day 11
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3
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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3 Soumillon et al
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2
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - C57BL/6J
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Fat and muscle
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Duda et al., 2018 - organism part - …
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Zhao et al., 2019 - tissue - lens
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Meierhofer et al., 2016 - organism part
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Proteomics
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Transcriptomics
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Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
2.5703 × 10-37.5
Gm6545'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
2.2935 × 10-1527.3
Gm6545'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.2232 × 10-1907.2
Gm6545'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
3.1684 × 10-1527.1
Gm6545'interleukin-28A; 1000 nanogram per milliliter' vs 'none'compoundTranscription profiling by high throughput sequencing of murine small intestinal epithelial cells stimulated with interleukin-28A
Adjusted p-valueLog2-fold change
8.6341 × 10-937
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.1715 × 10-2836.9
Gm6545'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
8.0538 × 10-5-6.2
Gm6545'Zbtb10 knockdown' vs 'control' at '6 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
4.0883 × 10-606
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.6984 × 10-745.9
Gm6545'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.7695 × 10-1915.8
Gm6545'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
7.4726 × 10-335.8
Gm6545'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.0118 × 10-1195.7
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.3526 × 10-965.6
Gm6545'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.8886 × 10-645.1
Gm6545'SARS coronavirus MA15; 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.3618 × 10-425
Gm6545'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.1307 × 10-185
Gm6545'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
1.4637 × 10-65
Gm6545"98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young"age, phenotypeRNAseq of whole ovarian follicles from young and old mice.
Adjusted p-valueLog2-fold change
4.2175 × 10-64.9
Gm6545'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
9.6173 × 10-714.8
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.4844 × 10-434.8
Gm6545'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.5815 × 10-3-4.8
Gm6545'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
3.9771 × 10-24.8
Gm6545'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
1.2797 × 10-554.7
Gm6545'Debaryomyces hansenii' at '24 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
8.1893 × 10-12-4.7
Gm6545'acute myeloid leukemia' vs 'myeloproliferative disorder'diseaseTranscription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm
Adjusted p-valueLog2-fold change
3.1137 × 10-174.5
Gm6545'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.5898 × 10-344.3
Gm6545'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
3.4379 × 10-104.3
Gm6545'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.2471 × 10-5-4.3
Gm6545'Zbtb10 knockdown' vs 'control' at '2 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
1.7613 × 10-694.2
Gm6545'SARS coronavirus MA15; 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.792 × 10-44.2
Gm6545'expression of Pax5' vs 'control (empty vector)'genotypeGermline Aberrations of PAX5 Cause Susceptibility to pre-B cell Acute Lymphoblastic Leukemia
Adjusted p-valueLog2-fold change
7.9465 × 10-334
Gm6545'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
2.0556 × 10-314
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.5051 × 10-9-3.9
Gm6545'diphtheria toxin; 30 nanogram per gram' vs 'none'stimulusRNA-seq of mouse brain tissue repopulating microglia in response to traumatic brain injury
Adjusted p-valueLog2-fold change
7.7686 × 10-43.9
Gm6545'status epilepticus' vs 'none' in 'microglia; none'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
1.663 × 10-373.8
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
9.2298 × 10-163.7
Gm6545'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
4.5489 × 10-4-3.6
Gm6545'Er1F/-' vs 'wild type genotype'genotypeRNA-Seq profiling of ERCC1-XPF DNA repair defect (Er1F/-) versus wild type (Er1F/+) macrophages
Adjusted p-valueLog2-fold change
5.4436 × 10-103.5
Gm6545'epithelium-specific Apc knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
1.8296 × 10-83.5
Gm6545'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.3062 × 10-53.5
Gm6545'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
9.7357 × 10-53.5
Gm6545'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
2.0432 × 10-363.4
Gm6545'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector'genotypeRNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice
Adjusted p-valueLog2-fold change
2.9784 × 10-223.4
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.6209 × 10-63.4
Gm6545'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
4.1386 × 10-63.4
Gm6545'curdlan' vs 'none' in 'wild type'compound, genotypeDendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway
Adjusted p-valueLog2-fold change
2.1884 × 10-3-3.4
Gm6545'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
3.2506 × 10-33.4
Gm6545'soticlestat; 30 milligram per kilogram' vs 'none' in 'astrocyte; none'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
5.4865 × 10-43.3
Gm6545'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.3436 × 10-23.3
Gm6545'expression of Pax5 G183S mutant' vs 'control (empty vector)'genotypeGermline Aberrations of PAX5 Cause Susceptibility to pre-B cell Acute Lymphoblastic Leukemia
Adjusted p-valueLog2-fold change
1.6407 × 10-2-3.2
Gm6545'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
3.7787 × 10-23.2
Gm6545'status epilepticus' vs 'none' in 'microglia; soticlestat; 30 milligram per kilogram'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
1.4656 × 10-683.1
Gm6545'SARS coronavirus MA15; 4 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
9.6739 × 10-53.1
Gm6545'Helicobacter hepaticus' vs 'none' in 'wild type phenotype'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
1.1095 × 10-33
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.6389 × 10-10-2.9
Gm6545'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'classical monocyte'cell type, genotypeRNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice
Adjusted p-valueLog2-fold change
5.6039 × 10-42.9
Gm6545'curdlan' vs 'none' in 'IL2 knockout'compound, genotypeDendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway
Adjusted p-valueLog2-fold change
4.2759 × 10-32.9
Gm6545'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-'compound, genotypeInhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2)
Adjusted p-valueLog2-fold change
4.084 × 10-62.8
Gm6545'Trichuris muris' vs 'control' in 'non wormy; caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
2.3439 × 10-42.8
Gm6545'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.3753 × 10-18-2.7
Gm6545'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
1.6874 × 10-12-2.7
Gm6545'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
5.2851 × 10-32.7
Gm6545'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
1.2084 × 10-82.5
Gm6545'Debaryomyces hansenii' at '6 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
1.6669 × 10-32.5
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
9.9873 × 10-32.5
Gm6545'lipopolysaccharide' vs 'none' in 'bone marrow; wild type'cell type, compound, genotypeTranscription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice
Adjusted p-valueLog2-fold change
2.346 × 10-22.5
Gm6545'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.1007 × 10-52.4
Gm6545'glioblastoma multiforme' vs 'normal'diseaseAnalysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus.
Adjusted p-valueLog2-fold change
1.0479 × 10-42.4
Gm6545'Influenza A virus' vs 'none'infectRNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals
Adjusted p-valueLog2-fold change
7.2171 × 10-3-2.4
Gm6545'MEF2A knockout' vs 'wild type genotype' in 'Hoxb8-FL; lipopolysaccharide; 10 nanogram per milliliter'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.9093 × 10-22.3
Gm6545'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
3.6759 × 10-42.2
Gm6545'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.7701 × 10-22.2
Gm6545'AZD7507; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.0856 × 10-6-2.1
Gm6545'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
7.9019 × 10-3-2.1
Gm6545'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
6.63 × 10-52
Gm6545'CpG ODN' vs 'PBS' at '24 hour'compound, timeTranscription profiling by array of mouse vaginal samples following adjuvant treatment
Adjusted p-valueLog2-fold change
2.0513 × 10-4-2
Gm6545"YFP positive" vs "YFP negative" in "lamina propria of small intestine"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
3.9556 × 10-4-2
Gm6545"muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP negative"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
6.4258 × 10-4-2
Gm6545'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
9.3047 × 10-4-2
Gm6545'R-17-92 knockout' vs 'control'phenotypeFollicular B (FoB) cells purified from miR-17-92 tKO mice, stimulated with LPS/IL-4, 13.5hr
Adjusted p-valueLog2-fold change
5.4307 × 10-61.9
Gm6545'macrophage; lipopolysaccharide stimulated' vs 'macrophage; unstimulated'cell type, treatmentGene expression profile of GM-CSF derived bone marrow dendritic cell subsets after LPS stimulation
Adjusted p-valueLog2-fold change
7.2943 × 10-41.9
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.4586 × 10-31.9
Gm6545'interferon gamma' vs 'dexamethasone; 100 nanomolar'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
2.931 × 10-21.9
Gm6545'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
5.0009 × 10-41.8
Gm6545'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
4.2342 × 10-31.8
Gm6545'Sall1 deficient microglia' vs 'wild type microglia'genotype, phenotypeRNA sequencing of microglia sorted form tamoxifen treated Sall1CreER/fl and control Sall1fl/fl mice
Adjusted p-valueLog2-fold change
2.5231 × 10-71.7
Gm6545'Id2_Id3_double knockout' vs 'wild type' in 'CD4+TCRb+CD8– cell; thymus'cell type, genotype, organism partTranscription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells
Adjusted p-valueLog2-fold change
5.2057 × 10-61.7
Gm6545'lymphocytic choriomeningitis virus WE' vs 'normal'diseaseTranscription profiling by array of lymphocytic choriomeningitis virus-strain WE (LCMV-WE) infected mice versus naive mice.
Adjusted p-valueLog2-fold change
1.765 × 10-2-1.7
Gm6545'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
9.3779 × 10-9-1.6
Gm6545'Rel -/-; Nfkb1-/-; CD4Cre Rela fx/fx' vs 'wild type genotype'genotypeRNA-seq of CD8 single positive thymocytes from WT and Rela fx/fx CD4Cre Nfkb1KO RelKO mice.
Adjusted p-valueLog2-fold change
1.9236 × 10-51.6
Gm6545'Runx3 knockout' vs 'wild type genotype'genotypeRunx3 function in CD8+ splenic T cells
Adjusted p-valueLog2-fold change
1.2546 × 10-3-1.6
Gm6545'10 month' vs '2 month'ageRNA-seq of adipocyte progenitor cells derived from old and young mice to investigate the molecular signature of aging
Adjusted p-valueLog2-fold change
1.7287 × 10-31.6
Gm6545'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
3.1676 × 10-21.6
Gm6545'FusΔNLS/+' vs 'wild type genotype' at '24 hour'genotype, timeMutant FUS triggers age-dependent synaptic impairment in presymptomatic ALS-FUS mice (RNA-seq part2)
Adjusted p-valueLog2-fold change
2.3103 × 10-51.5
Gm6545'3110043O21Rik knockout; liver' vs 'wild type genotype; liver'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
2.1677 × 10-21.5
Gm6545'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.7996 × 10-2-1.5
Gm6545'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
2.8213 × 10-2-1.5
Gm6545'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
1.1248 × 10-61.4
Gm6545'Influenza A virus' vs 'mock' in 'interleukin-22'infect, stimulusTranscription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza
Adjusted p-valueLog2-fold change
9.3156 × 10-61.4
Gm6545'Influenza A virus' vs 'mock' in 'IgG1'infect, stimulusTranscription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza
Adjusted p-valueLog2-fold change
2.4324 × 10-41.4
Gm6545'Reverbαflox/floxAlbCreERT2-' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
7.849 × 10-41.4
Gm6545'transgenic hepatic growth hormone and hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '40 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
5.5873 × 10-31.4
Gm6545'interferon gamma' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
2.0367 × 10-2-1.4
Gm6545'10 Gy Gray; x-ray' vs 'none' in 'tumor and stromal cell'cell type, irradiateRNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated
Adjusted p-valueLog2-fold change
2.4244 × 10-21.4
Gm6545'poly(I:C)' vs 'none'stimulus3’-Seq of ex vivo isolated mouse multipotent steady state hematopoietic stem cells (sHSC) and proliferating HSCs
Adjusted p-valueLog2-fold change
8.1883 × 10-71.3
Gm6545'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
2.8063 × 10-61.3
Gm6545'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.9501 × 10-51.3
Gm6545'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.7887 × 10-31.3
Gm6545'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
1.976 × 10-31.3
Gm6545'mir181a1/b1 Knockout' vs 'wild type'genotypeMouse CD4+/CD8+ thymocytes from miR-181a1/b1 KO vs WT
Adjusted p-valueLog2-fold change
2.4255 × 10-3-1.3
Gm6545'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.3128 × 10-21.3
Gm6545'transgenic hepatic growth hormone' vs 'wild type genotype' in '40 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
2.5957 × 10-2-1.3
Gm6545'Tumor Necrosis Factor' vs 'none'stimulusTranscription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor
Adjusted p-valueLog2-fold change
3.6062 × 10-21.3
Gm6545'Stat5ab+/null' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
4.4173 × 10-2-1.3
Gm6545'NFAT5 knock-out' vs 'wild type' in 'none'compound, genotypeTranscription profiling by array of mouse bone marrow derived macrophages mutant for NAT5 after treatment with lipopolysaccharide
Adjusted p-valueLog2-fold change
1.3057 × 10-41.2
Gm6545'MFP2 knockout' vs 'wild type'genotypeDefining the microglia transcriptome in multifunctional protein-2 deficient mice
Adjusted p-valueLog2-fold change
4.2218 × 10-3-1.2
Gm6545'Cd1d homozyous knockout' vs 'wild type genotype' in 'α-GalCer; 2 microgram'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
6.6553 × 10-31.2
Gm6545'organoid culture without Noggin (ER medium)' vs 'organoid culture (ENR medium)' in 'none'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
1.1395 × 10-2-1.2
Gm6545'Cbs knockout' vs 'wild type'genotypeGene expression profile of CD4-positive T cells from mouse Cbs knockout
Adjusted p-valueLog2-fold change
1.1747 × 10-21.2
Gm6545'Dicer knockout' vs 'wild type genotype'genotypeTranscription profiling by array of mouse Dicer-knockout CD4 T cells against wild type controls
Adjusted p-valueLog2-fold change
1.2798 × 10-21.2
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NZO/HILtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.4657 × 10-21.2
Gm6545'hepatocyte-specific Pten knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
5.2769 × 10-61.1
Gm6545'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.3647 × 10-51.1
Gm6545'30 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.2827 × 10-3-1.1
Gm6545'10 nanogram per milliliter; TGF-beta1' vs 'none' in 'common dendritic progenitor' at '24 hour'cell type, compound, timeDynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors
Adjusted p-valueLog2-fold change
4.2477 × 10-31.1
Gm6545'transgenic hepatic growth hormone and hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
1.0641 × 10-2-1.1
Gm6545'Rb;E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
2.0963 × 10-21.1
Gm6545'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.1654 × 10-21.1
Gm6545'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
1.4468 × 10-5-1
Gm6545'Rag1-/-' vs 'wild type'genotypeTranscription profiling by array of peritoneal macrophages from B6 wild type and B6-Rag1 knock-out mice
Adjusted p-valueLog2-fold change
2.6313 × 10-51
Gm6545'anti-CD3/anti-CD28' vs 'none' in 'empty vector'genotype, stimulusTranscription profiling by array of FOXP3 overexpression in resting and activated mouse CD4+ T cells
Adjusted p-valueLog2-fold change
2.9854 × 10-51
Gm6545'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.6618 × 10-3-1
Gm6545'Lmna G609G/G609G knock in' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Lmna Gly609Gly knock in
Adjusted p-valueLog2-fold change
2.9451 × 10-31
Gm6545'Roquinsan/san(sanroque)' vs 'wild type'genotypeExpression data from CD44loCD8+ T cells of sanroque versus wild-type mice
Adjusted p-valueLog2-fold change
5.475 × 10-3-1
Gm6545'transplanted with bone marrow from Tfr2 knockout mouse' vs 'transplanted with bone marrow from Tfr2 wild type mouse'stimulusRNAseq of the spleen of Hbb(th3/+) mice transplanted with bone marrow from Tfr2-ko or Tfr2 wt mice
Adjusted p-valueLog2-fold change
9.8621 × 10-31
Gm6545'SARS coronavirus MA15 E protein mutant Δ3' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
1.2062 × 10-2-1
Gm6545'E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.3058 × 10-21
Gm6545'inhibitor of kappaB kinase beta constitutively active-transgenic' vs 'wild type or single transgenic'genotypeTranscription profiling by array of embryonic mouse heart ventricles with and without cardiomycocyte-specific expression of constitutively active IKK2
Adjusted p-valueLog2-fold change
4.49 × 10-21
Gm6545'dexamethasone; 100 nanomolar; interferon gamma' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Ensembl gene
Ensembl transcript
MGI ID (Mouse)
MGI description
Gene biotype
Design element
A_55_P1987827, 10466314, 4545361