ENSRNOG00000001476 (Cldn4)

rattus norvegicus

claudin 4

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Rattus norvegicus
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Showing 1 experiment:
Created with Highcharts 6.2.0adult CCAP neuronalpha’/beta’ middle Kenyon cellcentrifugal neuron C3distal medullary amacrine neuron Dm10distal medullary amacrine neuron Dm9dopaminergic PAM neuron 6gamma dorsal Kenyon celllamina monopolar neuron L2lobula columnar neuron LC10alobula columnar neuron LC6lobula-lobula plate columnar neuron LLPC1mushroom body output neuronproximal medullary amacrine neuron Pm3transmedullary neuron Tm1transmedullary neuron Tm4adult lamina marginal glial cellalpha/beta posterior Kenyon cellcolumnar neuron T1distal medullary amacrine neuron Dm3dopaminergic PAM neuron 3dopaminergic PAM neuron 9lamina intrinsic neuronlamina monopolar neuron L5lobula columnar neuron LC10dlobula plate tangential neuronmedullary intrinsic neuron Mi4photoreceptor cell R7T neurontransmedullary neuron Tm29
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.0585 × 10-1344.7
Cldn4'2 weeks after L5 spinal nerve ligation' vs 'control'growth condition, timeRNA-seq of rat dorsal root ganglia after ligation to investigate central nervous system transcriptomics in chronic pain using agnostic splice site discovery methods
Adjusted p-valueLog2-fold change
1.8755 × 10-103.3
Cldn4'bromoethylamine; 60 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
3.4517 × 10-3-3.1
Cldn4'female duodenum' vs 'male duodenum'organism part, sexIdentification of sexually dimorphically expressed genes in rat tissues
Adjusted p-valueLog2-fold change
2.9101 × 10-33
Cldn4'1-napthylisothiocyanate; bile duct' at '6 hour' vs 'vehicle; bile duct' at '6 hour'compound, organism part, timeGene expression in hepatocytes and bile ducts from ANIT-treated rats
Adjusted p-valueLog2-fold change
5.8235 × 10-15-2.8
Cldn4'cyclophosphamide; 50 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.7358 × 10-112.8
Cldn4'nitrofurantoin; 10 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
1.5566 × 10-16-2.7
Cldn4'nitrofurantoin; 600 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
5.3244 × 10-14-2.7
Cldn4'ketoconazole; 10 milligram per kilogram' vs 'none' in 'ketoconazole; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
9.5551 × 10-13-2.7
Cldn4'cyclophosphamide; 150 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
5.446 × 10-32.7
Cldn4'24 hour culture at sarcomere length = 2.2 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
4.9209 × 10-122.6
Cldn4'cisplatin; 3 milligram per kilogram' vs 'none' in 'cisplatin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.9276 × 10-102.6
Cldn4'cyclosporine A; 300 milligram per kilogram' vs 'none' in 'cyclosporine A; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.2263 × 10-172.5
Cldn4'cyclophosphamide; 5 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.2131 × 10-152.5
Cldn4'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.4516 × 10-10-2.5
Cldn4'ciprofloxacin; 300 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.3937 × 10-4-2.5
Cldn4'female jejunum' vs 'male jejunum'organism part, sexIdentification of sexually dimorphically expressed genes in rat tissues
Adjusted p-valueLog2-fold change
1.4961 × 10-32.5
Cldn4'puromycin aminonucleoside; 40 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; kidney' at '8 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
2.7642 × 10-112.4
Cldn4'caffeine; 10 milligram per kilogram' vs 'none' in 'caffeine; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.1977 × 10-10-2.4
Cldn4'cyclophosphamide; 150 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.2319 × 10-72.4
Cldn4'caffeine; 100 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.3677 × 10-162.3
Cldn4'allopurinol; 15 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.7202 × 10-102.3
Cldn4'nitrofurantoin; 10 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
7.2073 × 10-10-2.3
Cldn4'indomethacin; 50 milligram per kilogram' vs 'none' in 'indomethacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
7.9744 × 10-42.3
Cldn4'lomustine; 6 milligram per kilogram' vs 'none' in 'lomustine; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
2.1466 × 10-11-2.2
Cldn4'indomethacin; 15 milligram per kilogram' vs 'none' in 'indomethacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
2.5885 × 10-102.2
Cldn4'imipramine; 30 milligram per kilogram' vs 'none' in 'imipramine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
2.6033 × 10-10-2.2
Cldn4'ethionine; 80 milligram per kilogram' vs 'none' in 'ethionine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
3.4414 × 10-10-2.2
Cldn4'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; kidney' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
9.7128 × 10-102.2
Cldn4'caffeine; 10 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.716 × 10-72.2
Cldn4'carboplatin; 30 milligram per kilogram' vs 'none' in 'carboplatin; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.4838 × 10-22.2
Cldn4'allopurinol; 150 milligram per kilogram' vs 'none' in 'allopurinol; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.796 × 10-2-2.2
Cldn4'monocrotaline; 30 milligram per kilogram' vs 'none' in 'monocrotaline; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
4.4527 × 10-122.1
Cldn4'captopril; 100 milligram per kilogram' vs 'none' in 'captopril; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.0157 × 10-10-2.1
Cldn4'puromycin aminonucleoside; 120 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.335 × 10-10-2.1
Cldn4'erythromycin ethylsuccinate; 100 milligram per kilogram' vs 'none' in 'erythromycin ethylsuccinate; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
5.271 × 10-82.1
Cldn4'puromycin aminonucleoside; 120 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
4.5876 × 10-72.1
Cldn4'gentamicin; 10 milligram per kilogram' vs 'none' in 'gentamicin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
1.5791 × 10-62.1
Cldn4'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
4.9351 × 10-52.1
Cldn4'puromycin aminonucleoside; 12 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
6.306 × 10-12-2
Cldn4'erythromycin ethylsuccinate; 1000 milligram per kilogram' vs 'none' in 'erythromycin ethylsuccinate; kidney' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
1.4339 × 10-9-2
Cldn4'omeprazole; 100 milligram per kilogram' vs 'none' in 'omeprazole; kidney' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
7.6815 × 10-72
Cldn4'bromobenzene; 30 milligram per kilogram' vs 'none' in 'bromobenzene; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
9.6639 × 10-72
Cldn4'bromoethylamine; 6 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
1.6025 × 10-42
Cldn4'allopurinol; 150 milligram per kilogram' vs 'none' in 'allopurinol; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
3.0307 × 10-32
Cldn4'puromycin aminonucleoside; 12 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
5.9868 × 10-32
Cldn4'lomustine; 6 milligram per kilogram' vs 'none' in 'lomustine; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
7.3474 × 10-32
Cldn4'japanese diet' vs 'regular diet' in 'kidney; SHRSP'diet, organism part, strainNdufc2 gene contributes to stroke susceptibility in the stroke-prone spontaneously hypertensive rat and it associates with juvenile ischemic stroke occurrence in humans
Adjusted p-valueLog2-fold change
6.7665 × 10-14-1.9
Cldn4'omeprazole; 1000 milligram per kilogram' vs 'none' in 'omeprazole; kidney' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
9.7563 × 10-13-1.9
Cldn4'allopurinol; 15 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
3.0742 × 10-111.9
Cldn4'cephalothin; 300 milligram per kilogram' vs 'none' in 'cephalothin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
5.5439 × 10-111.9
Cldn4'captopril; 300 milligram per kilogram' vs 'none' in 'captopril; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
7.9962 × 10-11-1.9
Cldn4'imipramine; 30 milligram per kilogram' vs 'none' in 'imipramine; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
5.4201 × 10-8-1.9
Cldn4'imipramine; 100 milligram per kilogram' vs 'none' in 'imipramine; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
3.4998 × 10-7-1.9
Cldn4'allopurinol; 50 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.6369 × 10-31.9
Cldn4'thioacetamide; 45 milligram per kilogram' vs 'none' in 'thioacetamide; kidney' at '4 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
1.4668 × 10-2-1.9
Cldn4'SHRSP' vs 'SHR/Mol' in 'kidney; japanese diet'diet, organism part, strainNdufc2 gene contributes to stroke susceptibility in the stroke-prone spontaneously hypertensive rat and it associates with juvenile ischemic stroke occurrence in humans
Adjusted p-valueLog2-fold change
2.2184 × 10-21.8
Cldn4'lomustine; 6 milligram per kilogram' vs 'none' in 'lomustine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
2.8794 × 10-21.8
Cldn4'nitrofurantoin; 100 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
5.7669 × 10-81.7
Cldn4'omeprazole; 100 milligram per kilogram' vs 'none' in 'omeprazole; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
3.4915 × 10-3-1.7
Cldn4'bromobenzene; 100 milligram per kilogram' vs 'none' in 'bromobenzene; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
3.964 × 10-31.7
Cldn4'methapyrilene; 100 milligram per kilogram' vs 'none' in 'methapyrilene; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
1.6684 × 10-2-1.7
Cldn4'phenylbutazone; 200 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.941 × 10-2-1.7
Cldn4'late stage of tumor development' vs 'normal'clinical informationTranscription profiling by array of rat esophagi with NMBA-induced squamous-cell carcinoma at different time points in tumor development
Adjusted p-valueLog2-fold change
3.8482 × 10-6-1.6
Cldn4'collagen sandwich' at '8 day' vs 'monolayer culture' at '8 day'growth condition, timeGenome-wide gene expression profiles of primary hepatocytes in two different culture systems over an 8-day period
Adjusted p-valueLog2-fold change
1.2205 × 10-31.6
Cldn4'sciatic nerve transection for neuropathic pain' vs 'sham surgery'treatmentTranscription profiling of dorsal root ganglia from rats with and without traumatic neuropathic pain from sciatic nerve transection to identify genes responsible for mechanical hypersensitivity
Adjusted p-valueLog2-fold change
1.0124 × 10-2-1.6
Cldn4'lomustine; 0.6 milligram per kilogram' vs 'none' in 'lomustine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
2.001 × 10-21.6
Cldn4'spinal cord transection' at '2 day' vs 'control' at '0 day'injury, timeTranscription profiling by array of adult rat tails following spinal cord transection
Adjusted p-valueLog2-fold change
3.606 × 10-31.5
Cldn4'allopurinol; 150 milligram per kilogram' vs 'none' in 'allopurinol; kidney' at '8 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.9159 × 10-2-1.5
Cldn4'methyltestosterone; 300 milligram per kilogram' vs 'none' in 'methyltestosterone; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
4.5046 × 10-2-1.5
Cldn4'cyclosporine A; 300 milligram per kilogram' vs 'none' in 'cyclosporine A; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
4.7637 × 10-21.5
Cldn4'ciprofloxacin; 300 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
4.8595 × 10-2-1.5
Cldn4'ethionine; 250 milligram per kilogram' vs 'none' in 'ethionine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
4.2396 × 10-171.4
Cldn4'indomethacin; 5 milligram per kilogram' vs 'none' in 'indomethacin; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
3.4652 × 10-41.4
Cldn4'allopurinol; 150 milligram per kilogram' vs 'none' in 'allopurinol; kidney' at '4 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.942 × 10-21.4
Cldn4'phenylbutazone; 200 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.8525 × 10-61.3
Cldn4'acetazolamide; 600 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
3.9397 × 10-5-1.3
Cldn4'bromoethylamine; 20 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
6.0492 × 10-31.3
Cldn4'triamterene; 150 milligram per kilogram' vs 'none' in 'triamterene; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
2.0482 × 10-2-1.3
Cldn4'cyclosporine A; 100 milligram per kilogram' vs 'none' in 'cyclosporine A; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.2608 × 10-2-1.3
Cldn4'early stage of tumor development' vs 'normal'clinical informationTranscription profiling by array of rat esophagi with NMBA-induced squamous-cell carcinoma at different time points in tumor development
Adjusted p-valueLog2-fold change
2.7621 × 10-21.3
Cldn4'phenylanthranilic acid; 1000 milligram per kilogram' vs 'none' in 'phenylanthranilic acid; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
3.5037 × 10-21.3
Cldn4'ciprofloxacin; 100 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
5.0677 × 10-3-1.2
Cldn4'skin expansion' at '20 hour' vs 'none' at '0 hour'stimulus, timeMicroarray data of rat expanded skin tissue
Adjusted p-valueLog2-fold change
1.0912 × 10-21.2
Cldn4'bromobenzene; 100 milligram per kilogram' vs 'none' in 'bromobenzene; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
1.0918 × 10-21.2
Cldn4'phenylbutazone; 20 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
2.2115 × 10-2-1.2
Cldn4'clofibrate; 30 milligram per kilogram' vs 'none' in 'clofibrate; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.6742 × 10-21.2
Cldn4'acetaminophen; 1000 milligram per kilogram' vs 'none' in 'acetaminophen; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
4.1807 × 10-2-1.2
Cldn4'experimental colitis' at '2 day' vs 'normal'disease, timeTranscription profiling of rats with colitis induced with trinitrobenzene sulfonate - time series
Adjusted p-valueLog2-fold change
4.1807 × 10-2-1.2
Cldn4'2 day' vs '0 day'timeTranscription profiling of rat trinitrobencenesulfonic acid (TNBS)-induced colitis model 2, 5, 7 and 14 days after TNBS treatment
Adjusted p-valueLog2-fold change
3.8886 × 10-61.1
Cldn4'allyl alcohol; 10 milligram per kilogram' vs 'none' in 'allyl alcohol; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
6.8268 × 10-3-1.1
Cldn4'allyl alcohol; 10 milligram per kilogram' vs 'none' in 'allyl alcohol; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.3744 × 10-2-1.1
Cldn4'bucetin; 300 milligram per kilogram' vs 'none' in 'bucetin; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
1.4091 × 10-21.1
Cldn4'allopurinol; 150 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.6318 × 10-21.1
Cldn4'puromycin aminonucleoside; 12 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
2.6264 × 10-21.1
Cldn4'rifampicin; 60 milligram per kilogram' vs 'none' in 'rifampicin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
4.2695 × 10-2-1.1
Cldn4'carboplatin; 100 milligram per kilogram' vs 'none' in 'carboplatin; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
4.7246 × 10-21.1
Cldn4'enalapril; 200 milligram per kilogram' vs 'none' in 'enalapril; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
4.9558 × 10-91
Cldn4'gentamicin; 100 milligram per kilogram' vs 'none' in 'gentamicin; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
1.4721 × 10-41
Cldn4'1.2 percent phosphorus containing diet for 24 days' vs 'control'dietEffect of a High Phosphorus Diet on Renal Gene Expressions in Rat
Adjusted p-valueLog2-fold change
1.5726 × 10-4-1
Cldn4'7 day' vs '0 day'timeTranscription profiling of rat trinitrobencenesulfonic acid (TNBS)-induced colitis model 2, 5, 7 and 14 days after TNBS treatment
Adjusted p-valueLog2-fold change
1.5726 × 10-4-1
Cldn4'experimental colitis' at '7 day' vs 'normal'disease, timeTranscription profiling of rats with colitis induced with trinitrobenzene sulfonate - time series
Adjusted p-valueLog2-fold change
9.4636 × 10-3-1
Cldn4'thioacetamide; 15 milligram per kilogram' vs 'none' in 'thioacetamide; kidney' at '8 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
1.7289 × 10-21
Cldn4'monocrotaline; 30 milligram per kilogram' vs 'none' in 'monocrotaline; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
2.8828 × 10-21
Cldn4'sulfasalazine; experimental colitis; 500 milligram per kilogram' vs 'none; experimental colitis; 'compound, diseaseTranscription profiling by array of rats with experimentally induced colitis after treatment with sulfasalazine
Adjusted p-valueLog2-fold change
4.9249 × 10-2-1
Cldn4'phenylbutazone; 60 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.