ENSRNOG00000004111 (Soat1)

rattus norvegicus

sterol O-acyltransferase 1

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Rattus norvegicus
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Showing 3 experiments:
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.4193 × 10-123.1
Soat1'cisplatin; 3 milligram per kilogram' vs 'none' in 'cisplatin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.679 × 10-173
Soat1'allopurinol; 15 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.3181 × 10-17-2.9
Soat1'allopurinol; 15 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.2494 × 10-172.9
Soat1'captopril; 100 milligram per kilogram' vs 'none' in 'captopril; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.7968 × 10-102.9
Soat1'caffeine; 10 milligram per kilogram' vs 'none' in 'caffeine; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
9.1265 × 10-152.8
Soat1'omeprazole; 100 milligram per kilogram' vs 'none' in 'omeprazole; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
6.7885 × 10-142.8
Soat1'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.6358 × 10-11-2.8
Soat1'indomethacin; 15 milligram per kilogram' vs 'none' in 'indomethacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
2.0204 × 10-9-2.8
Soat1'adult' vs 'neonate'developmental stageTranscription profiling by array of neonatal and adult rat ventricular cardiomyocytes
Adjusted p-valueLog2-fold change
6.2995 × 10-9-2.8
Soat1'indomethacin; 50 milligram per kilogram' vs 'none' in 'indomethacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
2.2436 × 10-72.8
Soat1'caffeine; 100 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.1951 × 10-162.7
Soat1'cyclophosphamide; 5 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.8084 × 10-152.7
Soat1'captopril; 300 milligram per kilogram' vs 'none' in 'captopril; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.5893 × 10-12-2.7
Soat1'ethionine; 80 milligram per kilogram' vs 'none' in 'ethionine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
7.2549 × 10-12-2.7
Soat1'cyclophosphamide; 150 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.0379 × 10-112.7
Soat1'caffeine; 10 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.4384 × 10-112.7
Soat1'gentamicin; 10 milligram per kilogram' vs 'none' in 'gentamicin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
6.9192 × 10-9-2.7
Soat1'allopurinol; 50 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.0796 × 10-9-2.6
Soat1'omeprazole; 100 milligram per kilogram' vs 'none' in 'omeprazole; kidney' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
2.2816 × 10-9-2.6
Soat1'imipramine; 100 milligram per kilogram' vs 'none' in 'imipramine; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
6.3121 × 10-62.6
Soat1'bromoethylamine; 60 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
7.6387 × 10-14-2.5
Soat1'omeprazole; 1000 milligram per kilogram' vs 'none' in 'omeprazole; kidney' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
9.816 × 10-14-2.5
Soat1'cyclophosphamide; 150 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
9.996 × 10-13-2.5
Soat1'erythromycin ethylsuccinate; 1000 milligram per kilogram' vs 'none' in 'erythromycin ethylsuccinate; kidney' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
2.751 × 10-72.5
Soat1'bromoethylamine; 6 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
9.4762 × 10-42.5
Soat1'EMD; 100 micromolar' vs 'DMSO' at '72 hour'compound, timeCross-species gene expression analysis of species-specific differences in preclinical assessment of pharmaceutical compounds (rat)
Adjusted p-valueLog2-fold change
6.4834 × 10-24-2.4
Soat1'nitrofurantoin; 600 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
2.1567 × 10-14-2.4
Soat1'cyclophosphamide; 50 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.3807 × 10-122.4
Soat1'nitrofurantoin; 10 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
8.0114 × 10-11-2.4
Soat1'imipramine; 30 milligram per kilogram' vs 'none' in 'imipramine; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
4.0792 × 10-102.4
Soat1'nitrofurantoin; 10 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
1.1143 × 10-32.4
Soat1'carboplatin; 30 milligram per kilogram' vs 'none' in 'carboplatin; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.4286 × 10-11-2.3
Soat1'erythromycin ethylsuccinate; 100 milligram per kilogram' vs 'none' in 'erythromycin ethylsuccinate; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
7.0453 × 10-11-2.3
Soat1'ketoconazole; 10 milligram per kilogram' vs 'none' in 'ketoconazole; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
9.6716 × 10-72.1
Soat1'imipramine; 10 milligram per kilogram' vs 'none' in 'imipramine; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
3.3533 × 10-42.1
Soat1'thioacetamide; 45 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
1.9854 × 10-7-2
Soat1'collagen sandwich' at '3 day' vs 'monolayer culture' at '3 day'growth condition, timeGenome-wide gene expression profiles of primary hepatocytes in two different culture systems over an 8-day period
Adjusted p-valueLog2-fold change
4.8595 × 10-2-2
Soat1'ethionine; 250 milligram per kilogram' vs 'none' in 'ethionine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
9.3969 × 10-9-1.9
Soat1'ciprofloxacin; 300 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
5.4796 × 10-7-1.9
Soat1'imipramine; 10 milligram per kilogram' vs 'none' in 'imipramine; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
3.1696 × 10-6-1.9
Soat1'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; kidney' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.4406 × 10-51.9
Soat1'bromobenzene; 30 milligram per kilogram' vs 'none' in 'bromobenzene; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
4.6031 × 10-51.9
Soat1'methapyrilene; 100 milligram per kilogram' vs 'none' in 'methapyrilene; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
2.5416 × 10-4-1.9
Soat1'allyl alcohol; 10 milligram per kilogram' vs 'none' in 'allyl alcohol; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
5.9909 × 10-4-1.9
Soat1'puromycin aminonucleoside; 120 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
6.1082 × 10-31.9
Soat1'phenylbutazone; 20 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
3.7142 × 10-91.8
Soat1'myocardial infarction; myocardial infarction' vs 'control; sham-operated left ventricle'disease, sampling siteTranscription profiling by array of rat hearts following myocardial infarction
Adjusted p-valueLog2-fold change
5.8009 × 10-7-1.8
Soat1'collagen sandwich' at '8 day' vs 'monolayer culture' at '8 day'growth condition, timeGenome-wide gene expression profiles of primary hepatocytes in two different culture systems over an 8-day period
Adjusted p-valueLog2-fold change
1.0337 × 10-61.8
Soat1'distal middle cerebral artery occlusion surgery; AAV7-hMANF infusion' vs 'sham; none'injury, treatmentRNA-seq of peri-infarct cortex of the rat dMCAO model of ischemic stroke treated with AAV7-hMANF or AAV7-GFP
Adjusted p-valueLog2-fold change
7.564 × 10-41.8
Soat1'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
8.2585 × 10-3-1.8
Soat1'bromobenzene; 100 milligram per kilogram' vs 'none' in 'bromobenzene; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
2.116 × 10-21.8
Soat1'lomustine; 6 milligram per kilogram' vs 'none' in 'lomustine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
2.3778 × 10-2-1.8
Soat1'thioacetamide; 15 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
1.8336 × 10-2-1.7
Soat1'phenylbutazone; 60 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.37 × 10-71.6
Soat1'cyclosporine A; 300 milligram per kilogram' vs 'none' in 'cyclosporine A; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.4811 × 10-71.6
Soat1'allyl alcohol; 10 milligram per kilogram' vs 'none' in 'allyl alcohol; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
7.339 × 10-3-1.6
Soat1'doxorubicin; 10 milligram per kilogram' vs 'none' in 'doxorubicin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
9.0175 × 10-3-1.6
Soat1'bucetin; 300 milligram per kilogram' vs 'none' in 'bucetin; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
1.1999 × 10-21.6
Soat1'puromycin aminonucleoside; 120 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.2095 × 10-21.6
Soat1'rifampicin; 60 milligram per kilogram' vs 'none' in 'rifampicin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.4134 × 10-2-1.6
Soat1'clofibrate; 30 milligram per kilogram' vs 'none' in 'clofibrate; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.6684 × 10-2-1.6
Soat1'phenylbutazone; 200 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.8534 × 10-21.6
Soat1'phenylbutazone; 200 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
2.9894 × 10-21.6
Soat1'nitrofurantoin; 100 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
5.647 × 10-61.5
Soat1'acetazolamide; 600 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
4.9916 × 10-4-1.5
Soat1'phenylbutazone; 60 milligram per kilogram' vs 'none' in 'phenylbutazone; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
2.0481 × 10-21.5
Soat1'thioacetamide; 15 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
2.6447 × 10-2-1.5
Soat1'5-alpha-dehydrotestestrone' vs 'control'compoundGene expression in rat ovaries treated with DHT
Adjusted p-valueLog2-fold change
3.8284 × 10-2-1.5
Soat1'triamterene; 50 milligram per kilogram' vs 'none' in 'triamterene; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
4.7246 × 10-21.5
Soat1'enalapril; 200 milligram per kilogram' vs 'none' in 'enalapril; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
5.7729 × 10-51.4
Soat1'WY-14643; 100 milligram per kilogram' vs 'none' in 'WY-14643; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with U to Z.
Adjusted p-valueLog2-fold change
2.1136 × 10-4-1.4
Soat1'bromoethylamine; 20 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
6.0907 × 10-31.4
Soat1'bucetin; 300 milligram per kilogram' vs 'none' in 'bucetin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
2.2065 × 10-21.3
Soat1'bromobenzene; 100 milligram per kilogram' vs 'none' in 'bromobenzene; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
4.5842 × 10-71.2
Soat1'myocardial infarction; peri-infarct region' vs 'control; sham-operated left ventricle'disease, sampling siteTranscription profiling by array of rat hearts following myocardial infarction
Adjusted p-valueLog2-fold change
1.3663 × 10-31.2
Soat1'experimental colitis' at '7 day' vs 'normal'disease, timeTranscription profiling of rats with colitis induced with trinitrobenzene sulfonate - time series
Adjusted p-valueLog2-fold change
1.3663 × 10-31.2
Soat1'7 day' vs '0 day'timeTranscription profiling of rat trinitrobencenesulfonic acid (TNBS)-induced colitis model 2, 5, 7 and 14 days after TNBS treatment
Adjusted p-valueLog2-fold change
2.1211 × 10-31.2
Soat1'none; experimental colitis' vs 'none; normal'compound, diseaseTranscription profiling by array of rats with experimentally induced colitis after treatment with sulfasalazine
Adjusted p-valueLog2-fold change
2.4041 × 10-31.2
Soat1'Streptococcus pneumoniae' vs 'control' in 'hippocampus' at '3 day'infect, organism part, timeTranscription profiling of rat hippocampus and cortex in the time series of Pneumococcal Meningitis infection
Adjusted p-valueLog2-fold change
2.2305 × 10-2-1.2
Soat1'lomustine; 0.6 milligram per kilogram' vs 'none' in 'lomustine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
1.7813 × 10-81.1
Soat1'24 hour culture at sarcomere length = 1.8 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
3.3624 × 10-81.1
Soat1'cephalothin; 300 milligram per kilogram' vs 'none' in 'cephalothin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
7.5935 × 10-5-1.1
Soat1'collagen sandwich' at '2 day' vs 'monolayer culture' at '2 day'growth condition, timeGenome-wide gene expression profiles of primary hepatocytes in two different culture systems over an 8-day period
Adjusted p-valueLog2-fold change
4.1736 × 10-3-1.1
Soat1'phenylbutazone; 200 milligram per kilogram' vs 'none' in 'phenylbutazone; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
3.4917 × 10-21.1
Soat1'ciprofloxacin; 100 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
4.7637 × 10-21.1
Soat1'ciprofloxacin; 300 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.0438 × 10-71
Soat1'24 hour culture at sarcomere length = 2.2 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
2.1284 × 10-5-1
Soat1'polysomal RNA' vs 'total RNA' in 'hydrogen peroxide; 0.2 millimolar'compound, fractionRegulation of total and polysomal RNA expression in rat neonatal cardiac myocytes by H2O2
Adjusted p-valueLog2-fold change
1.1351 × 10-2-1
Soat1'bisphenol A; 10^-9 molar' at '7 day' vs 'control; 10^-9 molar' at '7 day'compound, timeAssessment of low-dose bisphenol A (BPA) toxicity in rat thyroid follicular cells by gene expression microarray
Adjusted p-valueLog2-fold change
2.1027 × 10-2-1
Soat1'methyltestosterone; 300 milligram per kilogram' vs 'none' in 'methyltestosterone; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Synonym
Acat-1
Ortholog
ENSOARG00020018588 (Salmo salar), SOAT1 (Anas platyrhynchos), SOAT1 (Macaca mulatta), mboa-1 (Caenorhabditis elegans), ENSDNOG00000024026 (Dasypus novemcinctus), SOAT1 (Pongo abelii), SOAT1 (Bos taurus), SOAT1 (Gallus gallus), CG8112 (Drosophila melanogaster), Soat1 (Mus musculus), SOAT1 (Pan troglodytes), SOAT1 (Oryctolagus cuniculus), ARE1 (Saccharomyces cerevisiae), SOAT1 (Homo sapiens), soat1 (Danio rerio), ENSPANG00000022548 (Papio anubis), SOAT1 (Chlorocebus sabaeus), SOAT1 (Gorilla gorilla), ENSOARG00020022293 (Pan troglodytes), SOAT1 (Sus scrofa), SOAT1 (Equus caballus), ENSDNOG00000000607 (Dasypus novemcinctus), ARE2 (Saccharomyces cerevisiae), ENSMODG00000015032 (Monodelphis domestica), ENSDNOG00000048782 (Dasypus novemcinctus), soat1 (Tetraodon nigroviridis), ENSACAG00000028257 (Anolis carolinensis), ENSOANG00000040398 (Bos taurus), ENSDNOG00000000640 (Dasypus novemcinctus), ENSMODG00000006124 (Monodelphis domestica), soat1 (Xenopus tropicalis)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
Gene biotype
Design element
6135794, 5718606, 5755151, 6542773, 5838340, 6324126, 6094015, A_44_P170652, 10768979, 6339401, 6317758, 6039897, 6498638, 6144881, 6640616, 6101428, 6371229, D86373_s_at, 6144743, 1369002_at, 6628665
Reactome pathway ID