ensmusg00000015709 (Arnt2)

mus musculus

aryl hydrocarbon receptor nuclear translocator 2

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Mus musculus
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Showing 45 experiments:
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
4.8202 × 10-426.8
Arnt2'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
8.8823 × 10-7-5.1
Arnt2'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
1.1953 × 10-265-5
Arnt2'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.4659 × 10-44-4.9
Arnt2'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.6994 × 10-88-4.8
Arnt2'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.0932 × 10-264.8
Arnt2'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
2.7385 × 10-294.7
Arnt2'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
1.8645 × 10-2-4.5
Arnt2'Zbtb10 knockdown' vs 'control' at '2 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
1.4633 × 10-3-4.3
Arnt2'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
8.6876 × 10-204.2
Arnt2'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
8.2487 × 10-514
Arnt2'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.7289 × 10-7-3.8
Arnt2'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.8387 × 10-403.7
Arnt2'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
4.4781 × 10-353.7
Arnt2'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
6.649 × 10-43.7
Arnt2'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.491 × 10-203.6
Arnt2'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.8812 × 10-93.6
Arnt2'TGFβ, 5 nanogram per milliliter' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
1.436 × 10-123.5
Arnt2'acute myeloid leukemia' vs 'myeloproliferative disorder'diseaseTranscription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm
Adjusted p-valueLog2-fold change
5.4835 × 10-53.5
Arnt2'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
1.9835 × 10-153.4
Arnt2'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.7736 × 10-963.3
Arnt2'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
2.8046 × 10-103.3
Arnt2'Helicobacter hepaticus' vs 'none' in 'wild type phenotype'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
9.8042 × 10-43.3
Arnt2'recombinant human interleukin-2; 100 unit per milliliter; 10 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
3.3528 × 10-23.2
Arnt2'Gata6 knockout' vs 'wild type'phenotypeGlobal gene expression in the adult Gata6 null mouse pancreas
Adjusted p-valueLog2-fold change
1.3579 × 10-283.1
Arnt2'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
9.2493 × 10-223.1
Arnt2'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.2871 × 10-6-3.1
Arnt2'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.3958 × 10-33.1
Arnt2'recombinant human interleukin-2; 100 unit per milliliter; 12 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
1.5781 × 10-33
Arnt2'recombinant human interleukin-2; 100 unit per milliliter; 6 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
3.6594 × 10-862.8
Arnt2'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
2.2579 × 10-152.8
Arnt2'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2-GFP knockin; Egr2-GFP high'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
5.6972 × 10-8-2.8
Arnt2'dexamethasone (1 μM) and GW7647 (0.5 μM)' vs 'none'compoundRNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS
Adjusted p-valueLog2-fold change
2.2985 × 10-32.8
Arnt2'recombinant human interleukin-2; 100 unit per milliliter; 8 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
4.8469 × 10-3-2.8
Arnt2'Adipo-SIRT1' vs 'wild type genotype' in 'Ad libitum; 40 week'age, diet, genotypeGene expression analysis of adipose tissues from WT, Adipo-SIRT1 and Adipo-H363Y mice
Adjusted p-valueLog2-fold change
1.7752 × 10-322.7
Arnt2'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
9.3611 × 10-42.7
Arnt2'recombinant human interleukin-2; 100 unit per milliliter; 4 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
1.8817 × 10-3-2.7
Arnt2'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '12 month'age, genotypeErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression]
Adjusted p-valueLog2-fold change
4.8441 × 10-32.7
Arnt2'recombinant human interleukin-2; 100 unit per milliliter; 16 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
9.9112 × 10-3-2.7
Arnt2'Adipo-H363Y' vs 'wild type genotype' in 'Ad libitum; 40 week'age, diet, genotypeGene expression analysis of adipose tissues from WT, Adipo-SIRT1 and Adipo-H363Y mice
Adjusted p-valueLog2-fold change
2.1179 × 10-7-2.6
Arnt2'dexamethasone; 1 micromolar' vs 'none'compoundRNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS
Adjusted p-valueLog2-fold change
2.0049 × 10-42.6
Arnt2'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
6.4383 × 10-4-2.6
Arnt2'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
7.357 × 10-42.6
Arnt2'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
6.932 × 10-72.5
Arnt2'CHOP-/-' vs 'wild type' in 'DMSO'compound, genotypeMicroarray to find CHOP dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
1.2896 × 10-22.4
Arnt2'Tet2 knockout' vs 'wild type' in 'hematopoietic stem cell'cell type, genotypeTranscription profiling by high throughput sequencing of bone marrow stem and progenitor cells from Tet2 depleted mice
Adjusted p-valueLog2-fold change
3.1583 × 10-22.4
Arnt2'extracellular vesicle; EMT cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
1.1469 × 10-62.2
Arnt2'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
1.3754 × 10-3-2.2
Arnt2'T-cell depleted bone marrow transplant' vs 'none' in 'normal'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
6.8348 × 10-612.1
Arnt2'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
1.1397 × 10-122.1
Arnt2'epithelium-specific Apc knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
2.6901 × 10-4-2.1
Arnt2'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
3.4128 × 10-3-2.1
Arnt2'vehicle control; Nrf2 knockout' vs 'vehicle control; wild type genotype'RNA interference, compound, genotypeCharacterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling
Adjusted p-valueLog2-fold change
4.7672 × 10-112
Arnt2'Aire knockout' vs 'wild type' in 'cTEC'genotype, phenotypeTranscription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice
Adjusted p-valueLog2-fold change
1.4883 × 10-3-2
Arnt2'RA839; Nrf2 knockout' vs 'RA839; wild type genotype'RNA interference, compound, genotypeCharacterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling
Adjusted p-valueLog2-fold change
2.5553 × 10-32
Arnt2'neoplasm' vs 'normal tissue adjacent to neoplasm'sampling siteTranscription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa
Adjusted p-valueLog2-fold change
2.212 × 10-2-2
Arnt2'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
8.7647 × 10-171.9
Arnt2'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
1.5344 × 10-51.9
Arnt2'tristetrapolin knockout' vs 'wild type' in 'none' at '0 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.6704 × 10-4-1.9
Arnt2'glioblastoma multiforme' vs 'normal'diseaseAnalysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus.
Adjusted p-valueLog2-fold change
4.8948 × 10-41.9
Arnt2'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.023 × 10-31.9
Arnt2'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
1.7355 × 10-21.9
Arnt2'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'wild type'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Adjusted p-valueLog2-fold change
5.7588 × 10-91.8
Arnt2'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD8-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
3.653 × 10-61.8
Arnt2'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
1.2202 × 10-51.8
Arnt2'smoke; 3000 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.9553 × 10-51.8
Arnt2'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '30 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
3.0709 × 10-4-1.8
Arnt2'2'-fucosyllactose supplementation' vs 'control' in '8 weeks post-ileocecal resection'diet, treatmentTranscriptomic characterization of the impact of 2'-fucosyllactose supplementation on intestinal adaptation following ileocecal resection.
Adjusted p-valueLog2-fold change
2.3471 × 10-21.8
Arnt2'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
6.6615 × 10-61.7
Arnt2'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
7.766 × 10-61.7
Arnt2'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '60 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
2.9372 × 10-51.7
Arnt2'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.3029 × 10-41.7
Arnt2'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
5.2669 × 10-41.7
Arnt2'PS2APP transgenic' vs 'non transgenic' in 'microglia cell' at '13 month'age, cell type, genotypeTranscription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model
Adjusted p-valueLog2-fold change
4.1539 × 10-21.7
Arnt2'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
2.7212 × 10-71.6
Arnt2'9V/null' vs 'wild type' in 'saline; lung'compound, genotype, organism partGaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase [RNA-Seq]
Adjusted p-valueLog2-fold change
3.0691 × 10-51.6
Arnt2'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
5.1063 × 10-51.6
Arnt2'smoke; 1500 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
6.0235 × 10-51.6
Arnt2'adipose tissue specific Trim28 knockout' vs 'wild type genotype' in 'male'genotype, sexRNA-seq of gonadal adipose tissue from male and female Trim28-WT and Trim28 adipose specific KO mice
Adjusted p-valueLog2-fold change
7.332 × 10-51.6
Arnt2'smoke; 1500 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.6354 × 10-41.6
Arnt2'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.4735 × 10-41.6
Arnt2'Mycobacterium tuberculosis; DBA/2J congenic; 30 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
4.2096 × 10-4-1.6
Arnt2'Stat5abfl/fl;MMTV-Cre' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
5.0485 × 10-41.6
Arnt2'smoke; 1500 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
3.3932 × 10-41-1.5
Arnt2'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
2.6273 × 10-251.5
Arnt2'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
5.2529 × 10-11-1.5
Arnt2'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
4.8885 × 10-8-1.5
Arnt2'NrlGFP positive' vs 'NrlGFP negative'phenotypeTranscription profiling by array of photoreceptor precursor cells selected via cell surface antigen expression.
Adjusted p-valueLog2-fold change
2.5329 × 10-61.5
Arnt2'24 hour' vs '0 hour' in 'WT1-KTS'genotype, timeEWS-WT1 Oncogene Activates a Neuronal Reprogramming Factor ASCL1 and Mediates Partial Neural Differentiation
Adjusted p-valueLog2-fold change
2.2331 × 10-41.5
Arnt2'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
3.2392 × 10-4-1.5
Arnt2'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2; Il22-/-'genotype, irradiateRNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy
Adjusted p-valueLog2-fold change
3.2829 × 10-41.5
Arnt2'Cbfb knockout' vs 'control of Cbfb knockout'genotypeTranscription profiling by array of Mus musculus expressing Cbfb-MYH11
Adjusted p-valueLog2-fold change
1.0631 × 10-31.5
Arnt2'smoke; 3000 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
8.7209 × 10-31.5
Arnt2'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 15 days post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
9.2162 × 10-31.5
Arnt2'BAG6 homozygous knockout' vs 'wild type genotype'genotypeTranscription profiling of B16V mouse melanoma cells after BAG6 knockout to study impacts on extracellular vesicle mRNA cargo
Adjusted p-valueLog2-fold change
3.3668 × 10-7-1.4
Arnt2'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
1.5865 × 10-61.4
Arnt2'Tgfbeta inhibitor 20 micromolar' vs 'none'compoundExpression data from intestinal organoids altered for Tgfbeta signaling
Adjusted p-valueLog2-fold change
2.6491 × 10-61.4
Arnt2'Lmp7-/-Mecl1-/-' vs 'wild type'genotypeEffect of LMP7 and MECL1-immunoproteasome subunits deficiency on the transcriptome of mouse bone marrow-derived dendritic cells
Adjusted p-valueLog2-fold change
1.3631 × 10-51.4
Arnt2'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 2 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
6.3912 × 10-5-1.4
Arnt2'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
7.8273 × 10-51.4
Arnt2'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
3.1545 × 10-4-1.4
Arnt2'progesterone' vs 'vehicle' in 'SRC-2 mutant'compound, genotypeTranscription profiling by array of uteri of SRC-2 mutant mice treated with progesterone
Adjusted p-valueLog2-fold change
1.9922 × 10-21.4
Arnt2'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.2345 × 10-21.4
Arnt2'Mycobacterium tuberculosis H37Rv' vs 'none'infectThe global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice
Adjusted p-valueLog2-fold change
4.4551 × 10-21.4
Arnt2'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
3.3541 × 10-42-1.3
Arnt2'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1'cell type, growth condition, phenotypeTranscription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture
Adjusted p-valueLog2-fold change
1.903 × 10-91.3
Arnt2'mutant (Pdgfc-/-; Pdgfra GFP/+)' vs 'control'genotypeCerebral gene expression changes in Pdgfc and Pdgfra mutant
Adjusted p-valueLog2-fold change
7.7589 × 10-81.3
Arnt2'Mycobacterium tuberculosis H37Rv' vs 'none' in 'wild type'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
4.3276 × 10-61.3
Arnt2'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
7.7924 × 10-61.3
Arnt2'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
8.1154 × 10-61.3
Arnt2'Tgfbeta 1 ligand 0.04 nanogram per milliliter' vs 'none'compoundExpression data from intestinal organoids altered for Tgfbeta signaling
Adjusted p-valueLog2-fold change
8.1921 × 10-6-1.3
Arnt2'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
2.2405 × 10-41.3
Arnt2'CD2314' vs 'none' at '11 day'age, compoundTranscription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors
Adjusted p-valueLog2-fold change
2.3544 × 10-41.3
Arnt2'untreated; Csf2rb-/-' vs 'untreated; wild type'clinical history, genotypeMouse GM-CSF-related alveolar macrophage genome-wide expression data
Adjusted p-valueLog2-fold change
4.9004 × 10-41.3
Arnt2'calorie restricted diet' vs 'normal diet' at '15 month'age, dietTranscription profiling by array of cochleae from mice fed a calorie-restricted diet
Adjusted p-valueLog2-fold change
9.2463 × 10-4-1.3
Arnt2'inh-alpha/Tag transgenic' vs 'wild type' in 'none'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Adjusted p-valueLog2-fold change
9.5641 × 10-41.3
Arnt2'Crx knockout' vs 'control' at '6 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
1.5389 × 10-31.3
Arnt2'CD36 knockout' vs 'wild type genotype' in 'oxidized low density lipoprotein; 25 microgram per milliliter'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
2.6783 × 10-31.3
Arnt2'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
9.971 × 10-31.3
Arnt2'interleukin-36 alpha and beta and gamma' vs 'none'stimulusTranscriptional profiling of long-term stimulated primary murine intestinal fibroblasts with interleukin-36.
Adjusted p-valueLog2-fold change
1.3489 × 10-21.3
Arnt2'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.8715 × 10-2-1.3
Arnt2'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
1.9357 × 10-2-1.3
Arnt2'10 Gy Gray; x-ray' vs 'none' in 'tumor and stromal cell'cell type, irradiateRNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated
Adjusted p-valueLog2-fold change
2.9052 × 10-2-1.3
Arnt2'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector'genotypeRNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice
Adjusted p-valueLog2-fold change
6.1341 × 10-61.2
Arnt2'3 hour' vs '1 hour' in 'fetal bovine serum; 10 percent'growth condition, timeTranscriptomic changes in C3H10T1/2 cells exposed to lipid deprivation
Adjusted p-valueLog2-fold change
3.6707 × 10-5-1.2
Arnt2'doxycycline; 200 nanogram per milliliter; neoplasm; 12 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
2.217 × 10-41.2
Arnt2'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
4.133 × 10-4-1.2
Arnt2'progesterone' vs 'vehicle' in 'SRC-2 wild type'compound, genotypeTranscription profiling by array of uteri of SRC-2 mutant mice treated with progesterone
Adjusted p-valueLog2-fold change
7.7419 × 10-41.2
Arnt2'methionine- and choline-deficient, high fat diet mixed with 0.1% metformin' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
8.6154 × 10-41.2
Arnt2'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 2 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.2412 × 10-31.2
Arnt2'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 15 days post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.351 × 10-31.2
Arnt2'tumor' vs 'normal' in 'liver'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.4655 × 10-3-1.2
Arnt2'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
7.0014 × 10-121.1
Arnt2'Miz1 siRNA' vs 'non-targeting siRNA'RNA interferenceRNA-SEQ analysis of KMC murine pancreatic ductal adenocarcinoma (PDAC) cell line upon siRNA depletion of MYC, KRas or Miz1 (aka Zbtb17)
Adjusted p-valueLog2-fold change
4.0657 × 10-71.1
Arnt2'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
1.0729 × 10-6-1.1
Arnt2'10 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
6.0758 × 10-61.1
Arnt2'epithelium-specific mutant beta-catenin expression' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
1.2178 × 10-41.1
Arnt2'methionine- and choline-deficient, high fat diet' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
1.7782 × 10-41.1
Arnt2'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 70 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
5.58 × 10-41.1
Arnt2'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 30 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
8.2104 × 10-4-1.1
Arnt2'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 18.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
8.5294 × 10-41.1
Arnt2'5XFAD transgenic' vs 'wild type'genotypeTranscription profiling by array of microglia purified from wild type and TREM2 deficient microglia in a mouse model of Alzheimer's disease
Adjusted p-valueLog2-fold change
2.0204 × 10-31.1
Arnt2'Crx knockout' vs 'control' at '20 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
3.7539 × 10-31.1
Arnt2'Ihhd/d' vs 'wild type'genotypeGene expression profiling of conditional ablation of Indian hedgehog in the mouse uterus
Adjusted p-valueLog2-fold change
5.1584 × 10-31.1
Arnt2'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
5.8531 × 10-31.1
Arnt2'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
8.5204 × 10-31.1
Arnt2'Trichuris muris' vs 'control' in 'non wormy; caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.7477 × 10-2-1.1
Arnt2'Sik1 knockout; gonad adipose tissue' vs 'wild type genotype; gonad adipose tissue'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
1.4892 × 10-191
Arnt2'Mettl6 knockout clone D1' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
2.3801 × 10-7-1
Arnt2'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.9486 × 10-6-1
Arnt2'LKB1 knockout; floxed LKB1 with RIP-Cre' vs 'floxed LKB1 without RIP-Cre; wild type'genotype, phenotypeTranscription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice
Adjusted p-valueLog2-fold change
1.1549 × 10-5-1
Arnt2'K14-Cre-ERT2; none; UVB irradiation; 7 day' vs 'K14-Cre-ERT2; none; none'genotype, irradiate, timeAblation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin
Adjusted p-valueLog2-fold change
6.9485 × 10-51
Arnt2'3 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
3.5015 × 10-41
Arnt2'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 30 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
7.5496 × 10-41
Arnt2'intestinal smooth muscle culture supernatant' vs 'none' in 'organoid culture without Noggin (ER medium)'growth condition, stimulusRNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant
Adjusted p-valueLog2-fold change
9.4656 × 10-4-1
Arnt2'dinitrofluorobenzene' vs 'control' in 'Cnr1 -/- /Cnr2 -/-'compound, genotypeTranscription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity
Adjusted p-valueLog2-fold change
1.1958 × 10-31
Arnt2'Pax7 driven Mef2a overexpression' vs 'wild type'phenotypeMetabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk-Dio3 mega gene cluster.
Adjusted p-valueLog2-fold change
1.3 × 10-3-1
Arnt2Synacthen vs sodium chloride controlcompoundTranscription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses.
Adjusted p-valueLog2-fold change
2.4274 × 10-3-1
Arnt2'ReverbαFlox2-6AdipoCre+' vs 'ReverbαFlox2-6AdipoCre-' in 'high fat diet; 28 week'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
4.5394 × 10-31
Arnt2'50 micromolar; hydrogen peroxide' vs 'none'compoundTranscription profiling by array of mouse dermal fibroblasts after treatment with hydrogen peroxide
Adjusted p-valueLog2-fold change
6.1615 × 10-31
Arnt2'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Adjusted p-valueLog2-fold change
7.4691 × 10-3-1
Arnt2'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
1.2807 × 10-21
Arnt2'RBM20 antisense oligonucleotide' vs 'none' in 'wild type genotype'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
2.3964 × 10-2-1
Arnt2'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2'genotype, irradiateRNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy
Adjusted p-valueLog2-fold change
3.1474 × 10-21
Arnt2'one year after pulmonary macrophage transplantation; Csf2rb-/-' vs 'untreated; wild type'clinical history, genotypeMouse GM-CSF-related alveolar macrophage genome-wide expression data
Synonym
bHLHe1
Ortholog
ENSTNIG00000005978 (Bos taurus), Clk (Drosophila melanogaster), ENSTNIG00000004348 (Ciona savignyi), ARNT2 (Gallus gallus), ARNT2 (Homo sapiens), ARNT2 (Monodelphis domestica), ENSPANG00000015681 (Papio anubis), gce (Drosophila melanogaster), ENSACAG00000011731 (Anolis carolinensis), tgo (Drosophila melanogaster), ARNT2 (Sus scrofa), ARNT2 (Bos taurus), ARNT2 (Pan troglodytes), ARNT2 (Ornithorhynchus anatinus), aha-1 (Caenorhabditis elegans), Met (Drosophila melanogaster), arnt (Ciona intestinalis), ARNT2 (Dasypus novemcinctus), ARNT2 (Equus caballus), ENSOARG00020023147 (Pan troglodytes), ENSOCUG00000017566 (Oryctolagus cuniculus), Arnt2 (Rattus norvegicus), arnt2 (Xenopus tropicalis), ARNT2 (Pongo abelii), ENSGGOG00000012245 (Gorilla gorilla), ARNT2 (Macaca mulatta), ARNT2 (Anas platyrhynchos), ARNT2 (Chlorocebus sabaeus), ENSCSAVG00000010893 (Ciona savignyi), arnt2 (Danio rerio)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4848651, 4616727, 4657311, 5084869, 5115974, 4706449, 4430386, 5127045, 4946675, 116696_at, 4477355, 4454357, 4415820, 1420670_at, 5006373, 4934442, 4825483, D63644_s_at, 17492985, 5160477, 4882180, 5570286, 10565292, 4355408, 5026414, 4395064, 1434028_at, 92910_at, A_52_P260696, 4566957, 5379112, 4875453, 4952340, 4706629, 5220512, 4511723, ILMN_2616509, 4811103, 1420669_at, 5154369, A_30_P01021079, 5106289, 5591602, 4855564, 5234569, 5569446, 5434256, 4932240, 4920838, 4773219, 4617988, 4372500, 5455904, 5289029, 4349823, 5589464, 5352180
Reactome pathway ID