ensmusg00000068037 (Mas1)

mus musculus

MAS1 oncogene

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Mus musculus
Organism part
Showing 70 experiments:
image/svg+xml human body features 2009-05-27 Sjef text : Kevin (tsaitgaist) REDON http://commons.wikimedia.org/wiki/File:Human_body_features.svg cerebral cortex pleura brain heart breast thyroid gland adrenal gland lymph node bone marrow adipose tissue skeletal muscle leukocyte frontal cortex temporal lobe prefrontal cortex pituitary gland atrial appendage aorta coronary artery gastroesophageal junction left ventricle hippocampus hippocampus caecum ileum rectum nose tongue left atrium pulmonary valve mitral valve penis vas deferens seminal vesicle testis epididymis eye nasal septum oral cavity tonsil nasal pharynx lung spinal cord amygdala trachea throat bronchus tricuspid valve diaphragm liver stomach spleen duodenum gall bladder pancreas colon small intestine appendix smooth muscle urinary bladder prostate gland nerve cerebellum cerebellar hemisphere kidney renal cortex bone cartilage esophagus salivary gland parotid gland submandibular gland skin
Created with Highcharts 6.2.0adiposediaphragmhypothalamusolfactory apparatussigmoid colonurinary bladderaortabasal ganglionbreastcerebral cortexdura materesophagusfrontal cortexheart left ventricleleft kidneylower leg skinmiddle frontal gyrusmuscle of legparotid glandponspulmonary veinright cardiac atriumsmooth muscle tissuesubmandibular glandtestistibial nervevisual cortex
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68 FANTOM5 project - adult
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GTEX - organism part
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32 Uhlen's Lab
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Hallstrom et al., 2014 - Organism part
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68 FANTOM5 project - fetal
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19 NIH Epigenomics Roadmap
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Illumina Body Map
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HDBR developing brain - 9 post …
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ENCODE (M. Snyder lab)
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Mammalian Kaessmann
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Zhu et al., 2018 - Organism part
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Human Protein Atlas
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Human2021_Tissues - Wang et al. 2019
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Human Proteome Map - adult
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Doll et al., 2017 - Organism part
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brain regions
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Human Proteome Map - fetus
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ovary, pancreas, liver, subst. nigra
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Linscheid et al., 2020 – Tissues - …
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cerebellum and occipital lobe
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McKetney J et.al., 2019 - Individual - …
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Proteomics
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Transcriptomics
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Experiment type
Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
2.1347 × 10-9-7.5
Mas1'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
1.0042 × 10-137.1
Mas1'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.8191 × 10-5-5.3
Mas1'neural progenitor cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
3.7787 × 10-4-4.8
Mas1'neural stem cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
6.7712 × 10-174.2
Mas1'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
2.6823 × 10-143.9
Mas1'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
6.1901 × 10-3-3.7
Mas1'status epilepticus' vs 'none' in 'astrocyte; soticlestat; 30 milligram per kilogram'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
2.2956 × 10-3-3.6
Mas1'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.5887 × 10-33.6
Mas1'soticlestat; 30 milligram per kilogram' vs 'none' in 'astrocyte; none'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
5.2413 × 10-53.4
Mas1'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
3.1588 × 10-3-3.1
Mas1'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.9088 × 10-3-2.8
Mas1'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.3692 × 10-3-2.6
Mas1'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.1317 × 10-4-2.4
Mas1'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
6.8619 × 10-52
Mas1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
5.0272 × 10-4-2
Mas1'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
3.2424 × 10-61.9
Mas1'UPF2 knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
1.1334 × 10-3-1.9
Mas1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.3861 × 10-31.9
Mas1'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
5.8101 × 10-3-1.9
Mas1'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.0316 × 10-61.7
Mas1'tamoxifen; autosomal dominant polycystic kidney disease' vs 'none; normal'compound, disease, timeExpression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC
Adjusted p-valueLog2-fold change
6.2683 × 10-4-1.7
Mas1'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
1.9292 × 10-3-1.7
Mas1'Insm1-expressing endocrine progenitor cell' vs 'Insm1-lacking endocrine progenitor cell' in 'embryonic day 15.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
1.0931 × 10-2-1.7
Mas1'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
9.9843 × 10-31.6
Mas1'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
5.036 × 10-5-1.4
Mas1'nmf205, Gcn2 double mutant' vs 'wild type'genotypeTranscription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/-
Adjusted p-valueLog2-fold change
8.2849 × 10-5-1.4
Mas1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.7539 × 10-51.4
Mas1'high fat' vs 'chow' in 'NZO/HILtJ'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
3.194 × 10-31.4
Mas1'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
8.2294 × 10-3-1.4
Mas1'intermittent fasting every 16 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
2.9266 × 10-21.4
Mas1'Drosha -/-' vs 'wild type genotype'genotypeRNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs
Adjusted p-valueLog2-fold change
4.7362 × 10-8-1.3
Mas1'seizure-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle'clinical treatmentTranscription profiling by array of mice with epileptic tolerance
Adjusted p-valueLog2-fold change
3.7599 × 10-6-1.3
Mas1'nmf205 mutant' vs 'wild type'genotypeTranscription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/-
Adjusted p-valueLog2-fold change
3.03 × 10-5-1.3
Mas1'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.0772 × 10-31.3
Mas1'Reverbαflox/floxAlbCreERT2-' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
1.2362 × 10-3-1.3
Mas1'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
7.7694 × 10-3-1.3
Mas1'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.5872 × 10-2-1.3
Mas1'R6/2 transgenic' vs 'wild type' in '8 week; brain cortex'age, genotype, organism partTranscription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks.
Adjusted p-valueLog2-fold change
5.0623 × 10-6-1.2
Mas1'sham-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle'clinical treatmentTranscription profiling by array of mice with epileptic tolerance
Adjusted p-valueLog2-fold change
1.512 × 10-4-1.2
Mas1'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.0144 × 10-3-1.2
Mas1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.4151 × 10-31.2
Mas1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'biliary-derived proliferative ducts (bilDP)'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
3.9678 × 10-21.2
Mas1'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.2189 × 10-31.1
Mas1'transgenic hepatic growth hormone' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
2.3806 × 10-3-1.1
Mas1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.4625 × 10-31.1
Mas1'Reverbα -/-' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
5.8948 × 10-31.1
Mas1'Cnot3 knockout' vs 'wild type'phenotypeRNA-seq of mouse islets from Ins1-cre driven Cnot3 KO and control islets
Adjusted p-valueLog2-fold change
1.2984 × 10-3-1
Mas1'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
2.1259 × 10-2-1
Mas1'Npas4 shRNA' vs 'control shRNA' at '1 hour'RNA interference, timeRNAi profiling of mouse hippocampal neurons infected with lentivirus expressing Npas4-RNAi or control-RNAi to study Npas4-regulated genes
Synonym
MasR, Mas-1, Mas receptor
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4746988, 4503367, 1422936_at, 4578409, 4485636, 99439_at, 5506343, 17340902, 5259628, 5582568, 4710837, A_52_P655278, 4639741, A_55_P2173817, 5411184, 4493025, 5544277, 4343318, 4527167, 4661922, 5120278, 4795463, 4496751, ILMN_1253860, 4921247, 4733063, 10447848, A_55_P2130885, Msa.2436.0_at, 4477723, 4631872, A_51_P152623