-3.2 | | Fth1 | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
-2.8 | | Fth1 | 'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha' | genotype, stimulus | RNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment |
-2.8 | | Fth1 | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
2.7 | | Fth1 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-2.7 | | Fth1 | 'Yersinia pestis' vs 'control' in 'neutrophil' | cell type, infect, sampling site | Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague |
-2.6 | | Fth1 | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-2.5 | | Fth1 | 'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-2.5 | | Fth1 | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
2.4 | | Fth1 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-2.4 | | Fth1 | 'induced neural stem cell' vs 'mouse embryonic fibroblast cell' | cell type | Gene expression profile of mouse induced neural stem cells |
-2.3 | | Fth1 | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
2.1 | | Fth1 | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
2 | | Fth1 | 'lung carcinoma' vs 'normal' in 'lung cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
2 | | Fth1 | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
2 | | Fth1 | 'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
1.9 | | Fth1 | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
1.8 | | Fth1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.8 | | Fth1 | 'PS2APP transgenic' vs 'non transgenic' in 'microglia cell' at '13 month' | age, cell type, genotype | Transcription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model |
1.7 | | Fth1 | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
1.7 | | Fth1 | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
1.7 | | Fth1 | '21 percent oxygen, 37 degree Celsius, no serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
1.6 | | Fth1 | 'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte' | cell type, compound, genotype | Transcription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin |
-1.6 | | Fth1 | 'Irx3 knockout' vs 'control' at '1 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
1.6 | | Fth1 | 'extracellular vesicle; MET cell culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-1.6 | | Fth1 | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
1.6 | | Fth1 | 'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
1.6 | | Fth1 | '21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
1.5 | | Fth1 | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
1.5 | | Fth1 | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
1.5 | | Fth1 | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
1.4 | | Fth1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.4 | | Fth1 | 'Mycobacterium tuberculosis H37Rv' vs 'none' | infect | The global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice |
-1.4 | | Fth1 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.4 | | Fth1 | 'epithelium-specific mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1.4 | | Fth1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.4 | | Fth1 | 'dominant-negative Brg1' vs 'wild type' | genotype | Transcription profiling by array of lens tissue from mice expressing a dnBrg1 transgenic construct |
1.4 | | Fth1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.3 | | Fth1 | 'Irx3 knockout' vs 'control' at '7 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
1.3 | | Fth1 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.3 | | Fth1 | 'TGFβ, 5 nanogram per milliliter' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-1.3 | | Fth1 | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1.3 | | Fth1 | 'oral hard palate epithelium' vs 'tail skin epithelium' | organism part | Transcriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression |
-1.3 | | Fth1 | 'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs' | growth condition | RNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs |
1.2 | | Fth1 | 'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
1.2 | | Fth1 | 'lipopolysaccharide' vs 'none' in 'bone marrow; wild type' | cell type, compound, genotype | Transcription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice |
1.2 | | Fth1 | 'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
1.2 | | Fth1 | 'Notch 1 and 2 null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
1.2 | | Fth1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.2 | | Fth1 | 'follicle stimulating hormone and epidermal growth factor' vs '293H control medium' | growth condition | Transcription profiling by array of mouse cumulus cells after culture with growth differentiation factor 9 or follicle stimulating hormone and epidermal growth factor |
1.2 | | Fth1 | 'Col1a1-tetO-MLL/ENL' vs 'wild type' in 'hematopoietic stem cell' | cell type, genotype | Transcription profiling by high throughput sequencing of hematopoietic stem cells from a conditional-inducible mouse model of the MLL-ENL fusion oncogene |
-1.2 | | Fth1 | 'V6.5; embryonic stem cell’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
1.2 | | Fth1 | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
1.1 | | Fth1 | 'Influenza A virus' vs 'none' | infect | RNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals |
1.1 | | Fth1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.1 | | Fth1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.1 | | Fth1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.1 | | Fth1 | '9V/null' vs 'wild type' in 'saline; lung' | compound, genotype, organism part | Gaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase [RNA-Seq] |
1.1 | | Fth1 | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-1.1 | | Fth1 | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1.1 | | Fth1 | 'granulocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
1.1 | | Fth1 | '15 day' vs '3 day' | time | Transcription profiling time series of mouse embryonic chondrocyte differentiation |
1.1 | | Fth1 | 'anti-mPDL1; anti-mCTLA4; 10 milligram per kilogram' vs 'none' at '7 day' | compound, time | RNAseq of tumor samples from CT26 syngeneic mouse treated with a PD-L1 and CTLA-4 immunotherapy combination |
1.1 | | Fth1 | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1.1 | | Fth1 | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
1 | | Fth1 | 'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
-1 | | Fth1 | 'liver-specific Cnot3 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
-1 | | Fth1 | 'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1 | | Fth1 | 'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
1 | | Fth1 | 'Tumor Necrosis Factor' vs 'none' | stimulus | Transcription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor |
1 | | Fth1 | 'RBPjk null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
1 | | Fth1 | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-1 | | Fth1 | 'epithelium-specific Bcl9; Bcl9l knockout and mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1 | | Fth1 | '12 day' vs '3 day' | time | Transcription profiling time series of mouse embryonic chondrocyte differentiation |
1 | | Fth1 | 'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1 | | Fth1 | 'dysferlin mutant' vs 'wild type' in 'left ventricle cardiac muscle' | genotype, organism part | Transcription profiling by array of skeletal and cardiac muscle from dysferlin-deficient mice |
-1 | | Fth1 | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
1 | | Fth1 | 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day' | cell type, compound, time | Drug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs |
1 | | Fth1 | 'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
1 | | Fth1 | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2; Il22-/-' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
-1 | | Fth1 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |