ensmusg00000024661 (Fth1)

mus musculus

ferritin heavy polypeptide 1

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Mus musculus
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Showing 63 experiments:
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Created with Highcharts 6.2.0adrenal glandcaudal brain neural epitheliumdifferentiated myotubegonadkidneymesodermpituitary glandspleenvesicular glandaxillary lymph nodebraincoloncortex of kidneyembryonic tissueeyeheart right ventricleileumlivermaxillary archnon-floor plate neural epitheliumolfactory pitrenal medullaskeletal musclesubventricular zonetracheawhole organism
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - C57BL/6
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14 - embryonic day 10.5
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Mammalian Kaessmann
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Vertebrates
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Fat and muscle
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49 FANTOM5 project - embryonic day 11
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - C57BL/6J
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Organism part - Geiger et al
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Organism part - Huttlin et al
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Huttlin et al., 2010 - tissues - brain, …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Meierhofer et al., 2016 - organism part
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Linscheid et al. 2019 - organism part
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Deshmukh et al., 2015 - organism part
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Experimental variables
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.8119 × 10-107-3.2
Fth1'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
2.6686 × 10-17-2.8
Fth1'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha'genotype, stimulusRNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment
Adjusted p-valueLog2-fold change
8.4465 × 10-10-2.8
Fth1'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
2.5181 × 10-2482.7
Fth1'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
7.529 × 10-11-2.7
Fth1'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
1.1092 × 10-40-2.6
Fth1'epithelium-specific Apc knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
6.5309 × 10-83-2.5
Fth1'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
1.1067 × 10-7-2.5
Fth1'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.6178 × 10-632.4
Fth1'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
5.8318 × 10-11-2.4
Fth1'induced neural stem cell' vs 'mouse embryonic fibroblast cell'cell typeGene expression profile of mouse induced neural stem cells
Adjusted p-valueLog2-fold change
3.2251 × 10-33-2.3
Fth1'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil'cell type, genotypeRNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice
Adjusted p-valueLog2-fold change
5.9641 × 10-572.1
Fth1'3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
3.8448 × 10-192
Fth1'lung carcinoma' vs 'normal' in 'lung cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
1.028 × 10-62
Fth1'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
7.3186 × 10-52
Fth1'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
5.4484 × 10-681.9
Fth1'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
3.3168 × 10-281.8
Fth1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.7989 × 10-51.8
Fth1'PS2APP transgenic' vs 'non transgenic' in 'microglia cell' at '13 month'age, cell type, genotypeTranscription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model
Adjusted p-valueLog2-fold change
7.2774 × 10-701.7
Fth1'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.3132 × 10-181.7
Fth1'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
3.181 × 10-61.7
Fth1'21 percent oxygen, 37 degree Celsius, no serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
8.5464 × 10-2071.6
Fth1'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
2.6663 × 10-56-1.6
Fth1'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.1324 × 10-221.6
Fth1'extracellular vesicle; MET cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
1.2429 × 10-8-1.6
Fth1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
1.1522 × 10-71.6
Fth1'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
4.4305 × 10-21.6
Fth1'21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
7.4804 × 10-531.5
Fth1'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
2.0486 × 10-431.5
Fth1'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
8.7258 × 10-201.5
Fth1'Helicobacter hepaticus' vs 'none' in 'wild type phenotype'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
3.1505 × 10-261.4
Fth1'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.4504 × 10-181.4
Fth1'Mycobacterium tuberculosis H37Rv' vs 'none'infectThe global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice
Adjusted p-valueLog2-fold change
5.9738 × 10-16-1.4
Fth1'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.4633 × 10-14-1.4
Fth1'epithelium-specific mutant beta-catenin expression' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
9.0035 × 10-101.4
Fth1'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.0204 × 10-41.4
Fth1'dominant-negative Brg1' vs 'wild type'genotypeTranscription profiling by array of lens tissue from mice expressing a dnBrg1 transgenic construct
Adjusted p-valueLog2-fold change
2.0164 × 10-41.4
Fth1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.4943 × 10-44-1.3
Fth1'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.2806 × 10-251.3
Fth1'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.5125 × 10-9-1.3
Fth1'TGFβ, 5 nanogram per milliliter' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
2.4243 × 10-7-1.3
Fth1'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.0453 × 10-51.3
Fth1'oral hard palate epithelium' vs 'tail skin epithelium'organism partTranscriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression
Adjusted p-valueLog2-fold change
4.2171 × 10-2-1.3
Fth1'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
3.7813 × 10-1221.2
Fth1'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
6.1486 × 10-351.2
Fth1'lipopolysaccharide' vs 'none' in 'bone marrow; wild type'cell type, compound, genotypeTranscription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice
Adjusted p-valueLog2-fold change
1.9234 × 10-331.2
Fth1'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
2.8457 × 10-201.2
Fth1'Notch 1 and 2 null' vs 'wild type'genotypeQuantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS
Adjusted p-valueLog2-fold change
1.4331 × 10-71.2
Fth1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.025 × 10-51.2
Fth1'follicle stimulating hormone and epidermal growth factor' vs '293H control medium'growth conditionTranscription profiling by array of mouse cumulus cells after culture with growth differentiation factor 9 or follicle stimulating hormone and epidermal growth factor
Adjusted p-valueLog2-fold change
1.8275 × 10-41.2
Fth1'Col1a1-tetO-MLL/ENL' vs 'wild type' in 'hematopoietic stem cell'cell type, genotypeTranscription profiling by high throughput sequencing of hematopoietic stem cells from a conditional-inducible mouse model of the MLL-ENL fusion oncogene
Adjusted p-valueLog2-fold change
3.7666 × 10-4-1.2
Fth1'V6.5; embryonic stem cell’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
4.2922 × 10-31.2
Fth1'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.0477 × 10-281.1
Fth1'Influenza A virus' vs 'none'infectRNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals
Adjusted p-valueLog2-fold change
2.6127 × 10-131.1
Fth1'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.9418 × 10-111.1
Fth1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.7158 × 10-91.1
Fth1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.7825 × 10-71.1
Fth1'9V/null' vs 'wild type' in 'saline; lung'compound, genotype, organism partGaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase [RNA-Seq]
Adjusted p-valueLog2-fold change
1.9354 × 10-61.1
Fth1'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
1.0925 × 10-5-1.1
Fth1'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
3.0363 × 10-51.1
Fth1'granulocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
1.221 × 10-41.1
Fth1'15 day' vs '3 day'timeTranscription profiling time series of mouse embryonic chondrocyte differentiation
Adjusted p-valueLog2-fold change
4.2516 × 10-31.1
Fth1'anti-mPDL1; anti-mCTLA4; 10 milligram per kilogram' vs 'none' at '7 day'compound, timeRNAseq of tumor samples from CT26 syngeneic mouse treated with a PD-L1 and CTLA-4 immunotherapy combination
Adjusted p-valueLog2-fold change
9.5644 × 10-31.1
Fth1'12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
1.775 × 10-21.1
Fth1'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
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Log2-fold change
1
Fth1'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
7.4803 × 10-36-1
Fth1'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
8.1444 × 10-22-1
Fth1'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
1.8684 × 10-21-1
Fth1'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none'compoundRNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours
Adjusted p-valueLog2-fold change
1.3261 × 10-151
Fth1'Tumor Necrosis Factor' vs 'none'stimulusTranscription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor
Adjusted p-valueLog2-fold change
2.3023 × 10-111
Fth1'RBPjk null' vs 'wild type'genotypeQuantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS
Adjusted p-valueLog2-fold change
7.7994 × 10-111
Fth1'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
1.8947 × 10-8-1
Fth1'epithelium-specific Bcl9; Bcl9l knockout and mutant beta-catenin expression' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
5.6379 × 10-61
Fth1'12 day' vs '3 day'timeTranscription profiling time series of mouse embryonic chondrocyte differentiation
Adjusted p-valueLog2-fold change
1.6584 × 10-51
Fth1'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.2599 × 10-5-1
Fth1'dysferlin mutant' vs 'wild type' in 'left ventricle cardiac muscle'genotype, organism partTranscription profiling by array of skeletal and cardiac muscle from dysferlin-deficient mice
Adjusted p-valueLog2-fold change
5.5343 × 10-5-1
Fth1'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
7.5292 × 10-51
Fth1'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day'cell type, compound, timeDrug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs
Adjusted p-valueLog2-fold change
3.7561 × 10-41
Fth1'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
4.1452 × 10-41
Fth1'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2; Il22-/-'genotype, irradiateRNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy
Adjusted p-valueLog2-fold change
3.2631 × 10-3-1
Fth1'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system