6.7 | | Ly6c1 | 'dextran sodium sulfate' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion |
6.4 | | Ly6c1 | 'dexamethasone; 100 nanomolar; interferon gamma' vs 'none' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
6.3 | | Ly6c1 | 'interferon gamma' vs 'dexamethasone; 100 nanomolar' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
5.9 | | Ly6c1 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
5.7 | | Ly6c1 | 'interferon gamma' vs 'none' in 'dexamethasone; 100 nanomolar' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
5.7 | | Ly6c1 | 'interferon gamma' vs 'none' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
5.2 | | Ly6c1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
5.1 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
4.9 | | Ly6c1 | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-4.7 | | Ly6c1 | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
4.6 | | Ly6c1 | 'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
4.4 | | Ly6c1 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
4.4 | | Ly6c1 | 'Citrobacter rodentium' vs 'none' | infect | RNAseq of colon intestinal epithelium extracted from mice infected with Citrobacter rodentium |
4.3 | | Ly6c1 | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
4.1 | | Ly6c1 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
4.1 | | Ly6c1 | 'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar' | compound, genotype | Overexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment |
4.1 | | Ly6c1 | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
3.8 | | Ly6c1 | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
3.7 | | Ly6c1 | 'p150 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA' | RNA interference | RNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells |
3.6 | | Ly6c1 | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD8-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
-3.5 | | Ly6c1 | 'TGFβ, 5 nanogram per milliliter' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-3.3 | | Ly6c1 | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
3.3 | | Ly6c1 | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
3.3 | | Ly6c1 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
3.3 | | Ly6c1 | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
-3.3 | | Ly6c1 | '4μ8C; 15 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | Overexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment |
3.3 | | Ly6c1 | 'dexamethasone; 10 microgram per milliliter' vs 'none' | compound | RNA-seq of mouse sciatic peripheral nerve of injured mouse with implant: control (untreated) vs local delivery of MCC950 (NLRP3inh) vs standard FBR treatment dexamethasone (Dex). . |
-3.2 | | Ly6c1 | 'Irx3 knockout' vs 'control' at '1 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
3.1 | | Ly6c1 | 'interleukin-22 (Mus Musculus); 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
3.1 | | Ly6c1 | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-3.1 | | Ly6c1 | 'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha' | genotype, stimulus | RNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment |
-3.1 | | Ly6c1 | 'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
3 | | Ly6c1 | 'colitis' at '12 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-3 | | Ly6c1 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
2.9 | | Ly6c1 | 'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
2.9 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.9 | | Ly6c1 | 'interleukin-28A; 1000 nanogram per milliliter' vs 'none' | compound | Transcription profiling by high throughput sequencing of murine small intestinal epithelial cells stimulated with interleukin-28A |
-2.9 | | Ly6c1 | 'extracellular vesicle; EMT cell culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-2.8 | | Ly6c1 | '21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
2.8 | | Ly6c1 | 'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.7 | | Ly6c1 | 'interferon gamma; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
2.7 | | Ly6c1 | 'wild type; SARS MA15; 2 day' vs 'wild type; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
2.7 | | Ly6c1 | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
2.7 | | Ly6c1 | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
2.7 | | Ly6c1 | 'SARS coronavirus MA15 dORF6' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
2.6 | | Ly6c1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.6 | | Ly6c1 | '10 Gy Gray; x-ray' vs 'none' in 'tumor and stromal cell' | cell type, irradiate | RNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated |
2.6 | | Ly6c1 | 'Duchenne muscular dystrophy' vs 'normal' | disease | RNA-seq comparison of immortalised myoblasts from dystrophic and WT mice |
2.6 | | Ly6c1 | 'Lin- Dapi-EpCAM- CD31+td-tomato+' vs 'Lin- Dapi-EpCAM- CD31+td-tomato-' in 'vascular endothelial cell' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
2.6 | | Ly6c1 | 'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
2.6 | | Ly6c1 | 'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
2.6 | | Ly6c1 | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
2.6 | | Ly6c1 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
2.5 | | Ly6c1 | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
2.5 | | Ly6c1 | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
2.5 | | Ly6c1 | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
2.4 | | Ly6c1 | 'Influenza A virus (A/Scotland/20/1974(H3N2))' vs 'none' | infect | RNA-seq of mouse colon to investigate how influenza infection leads to intestinal disorders |
2.3 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.3 | | Ly6c1 | 'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
2.3 | | Ly6c1 | 'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
2.3 | | Ly6c1 | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
2.2 | | Ly6c1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2.2 | | Ly6c1 | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
2.2 | | Ly6c1 | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
2.2 | | Ly6c1 | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
2.1 | | Ly6c1 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.1 | | Ly6c1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2.1 | | Ly6c1 | 'Il10-/-' vs 'wild type genotype' in 'none' | compound, genotype | RNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion |
2.1 | | Ly6c1 | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2 | | Ly6c1 | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
2 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
2 | | Ly6c1 | 'colitis' at '19 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
2 | | Ly6c1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-2 | | Ly6c1 | 'Abcc8-/-' vs 'wild type genotype' in 'normal; male' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
2 | | Ly6c1 | 'interferon gamma; 1 nanogram per milliliter' vs 'none' | stimulus | Analysis of transcriptomes in intestinal stem cells in response to Interferon gamma |
2 | | Ly6c1 | 'lipid nanoparticle complexed with ribonucleic acid expressing respiratory synctial virus F protein' vs 'phosphate buffered saline' | stimulus | Microarray analysis of mouse whole genome using self-amplifying messenger (SAM) RNA delivered with different formulations compared to controls |
-1.9 | | Ly6c1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '14 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
-1.9 | | Ly6c1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '60 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.9 | | Ly6c1 | 'K14-Cre-ERT2 / CK1α fl/fl; 4-hydroxytamoxifen; none; 14 day' vs 'K14-Cre-ERT2; none; none' | genotype, irradiate, time | Ablation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin |
-1.9 | | Ly6c1 | 'CEBPa K159Q/K298Q expression' vs 'wild type CEBPa expression' | genotype | Transcriptome profiling of wild type, K159/298Q- and K159/298R- C/EBPα expressing mouse cells |
1.9 | | Ly6c1 | 'carotid body' vs 'adrenal medulla' | organism part | Expression profile of mouse carotid body and adrenal medulla [RNA-Seq] |
-1.9 | | Ly6c1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.9 | | Ly6c1 | 'Apc knockout in Villin1 positive cells' vs 'wild type' | phenotype | Transcription profiling by array of Apc-deficient proximal colonic epithelium upon Msx1 transcription factor depletion |
-1.8 | | Ly6c1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '14 day' vs 'none' at '6 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
-1.8 | | Ly6c1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '60 day' vs 'none' at '6 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.8 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.8 | | Ly6c1 | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
1.8 | | Ly6c1 | '3D culture' vs '2D culture' | growth condition | mRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture |
1.8 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.8 | | Ly6c1 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.8 | | Ly6c1 | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
-1.8 | | Ly6c1 | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2-GFP knockin; Egr2-GFP high' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
-1.8 | | Ly6c1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.8 | | Ly6c1 | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.8 | | Ly6c1 | 'NOD allele at SNP rs50454566' vs 'wild type genotype' | genotype | RNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene |
1.7 | | Ly6c1 | 'Plasmodium berghei ANKA' at '7 day' vs 'none' at '0 day' in 'none' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
-1.7 | | Ly6c1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '10 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.7 | | Ly6c1 | 'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector' | genotype | RNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice |
1.7 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.7 | | Ly6c1 | 'Vgamma4+, IL-17+' at '21 month' vs '3 month' | age, phenotype | RNA sequencing of gamma-delta T cell subsets from young and old mice |
1.6 | | Ly6c1 | 'Plasmodium berghei ANKA' at '6 day' vs 'none' at '0 day' in 'none' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
-1.6 | | Ly6c1 | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
-1.6 | | Ly6c1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '10 day' vs 'none' at '6 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
-1.6 | | Ly6c1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.6 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.6 | | Ly6c1 | 'Dyrk1 deletion' vs 'wild type' | phenotype | Whole transcriptome sequencing of mouse regulatory T cells with and without Mef2d, Mef2c, HDAC1, HDAC2 or Dyrk1 deletion |
1.6 | | Ly6c1 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.6 | | Ly6c1 | 'PAI1 knockout; SARS MA15; 4 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.6 | | Ly6c1 | 'doxycycline; 200 nanogram per milliliter; neoplasm; 12 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1.6 | | Ly6c1 | 'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol' | genotype, treatment | Transcription profiling by high throughput sequencing of uterine-specific Tsc2-null mice |
1.6 | | Ly6c1 | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.6 | | Ly6c1 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1.5 | | Ly6c1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '6 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.5 | | Ly6c1 | '10 Gy Gray; x-ray' vs 'none' in 'hematopoietic cell' | cell type, irradiate | RNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated |
1.5 | | Ly6c1 | 'wild type genotype; SARS MA15; 7 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.5 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.5 | | Ly6c1 | 'TIMP1 knockout; SARS MA15; 4 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.5 | | Ly6c1 | 'Ts1Rhr; KRASG12D' vs 'wild type genotype' | genotype | RNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D |
-1.5 | | Ly6c1 | 'actinomycin D; 8 hour' vs 'none' in 'Alb-Cre-ERT2 / Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.5 | | Ly6c1 | 'organoid culture without Noggin (ER medium)' vs 'organoid culture (ENR medium)' in 'none' | growth condition, stimulus | RNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant |
1.5 | | Ly6c1 | 'Tumor Necrosis Factor' vs 'none' | stimulus | Transcription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor |
-1.4 | | Ly6c1 | 'nuclear translocation of Mbd3b' at '48 hour' vs 'none' at '0 hour' | stimulus, time | Transcription profiling by RNA-seq during NuRD complex induction in mouse embryonic stem cells |
1.4 | | Ly6c1 | 'none; XPF knockout' vs 'all-trans-retinoic acid; 10 micromolar; wild type genotype' | compound, genotype | RNA-seq of mouse DNA repair endonuclease XPF knock out versus wild type and versus trans retinoic acid (tRA) treated wild type |
1.4 | | Ly6c1 | 'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.4 | | Ly6c1 | 'all-trans-retinoic acid; 10 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of mouse DNA repair endonuclease XPF knock out versus wild type and versus trans retinoic acid (tRA) treated wild type |
1.4 | | Ly6c1 | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
-1.4 | | Ly6c1 | 'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
1.4 | | Ly6c1 | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
1.4 | | Ly6c1 | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
1.4 | | Ly6c1 | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'biliary-derived proliferative ducts (bilDP)' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
1.4 | | Ly6c1 | 'viral replicon particle expressing respiratory synctial virus F protein' vs 'phosphate buffered saline' | stimulus | Microarray analysis of mouse whole genome using self-amplifying messenger (SAM) RNA delivered with different formulations compared to controls |
1.3 | | Ly6c1 | 'Ezh2 knockout' vs 'control' in 'CD62Llo regulatory T cell' | cell type, genotype | Transcription profiling by high throughput sequencing of mice with a partial or complete deletion of Ezh2 in regulatory T cells |
1.3 | | Ly6c1 | 'Influenza A virus' vs 'mock' in 'IgG1' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
-1.3 | | Ly6c1 | '4μ8C; 15 micromolar' vs 'none' in 'T-helper 2 cell' at '6 day' | cell type, compound, time | Effect of the IRE1a-XBP1 pathway inhibition during T helper 2 differentiation |
1.3 | | Ly6c1 | 'PAI1 knockout; SARS MA15; 7 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.3 | | Ly6c1 | 'SARS coronavirus MA15' vs 'none' in 'STAT1 -/-' at '5 day' | genotype, infect, time | Transcriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds |
1.3 | | Ly6c1 | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.3 | | Ly6c1 | 'rosiglitazone; 100 nanomolar' vs 'none' in 'wild type genotype' | compound, genotype | Transcriptional response to Rosiglitazone in adipocyte progenitors isolated from WT and Cited4-KO scWAT |
-1.3 | | Ly6c1 | 'Abcc8-/-' vs 'wild type genotype' in 'normal; female' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
1.2 | | Ly6c1 | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram; Plasmodium berghei ANKA; 7 day' vs 'none; none; 0 day' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.2 | | Ly6c1 | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1.2 | | Ly6c1 | 'Gucy2c S839I mutant' vs 'wild type genotype' | genotype | Transcriptomic analysis of the distal colon of wild type C57BL/6N mice and mice harboring a mutation (S839I) in Gucy2c |
1.2 | | Ly6c1 | 'cancer' vs 'normal' in 'lymph node medullary sinus macrophage' | cell type, disease | RNA Sequencing of CD169+ lymph node macrophages isolated from naïve or tumor-bearing mice |
1.2 | | Ly6c1 | 'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
1.2 | | Ly6c1 | 'SARS coronavirus MA15 E protein mutant Δ3' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1.2 | | Ly6c1 | '10 month' vs '2 month' | age | RNA-seq of adipocyte progenitor cells derived from old and young mice to investigate the molecular signature of aging |
1.2 | | Ly6c1 | 'SARS coronavirus MA15; 10^2 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.1 | | Ly6c1 | 'AZD8835; 50 milligram per kilogram' vs 'none' at '14 day' | compound, time | RNAseq of tumor samples from CT26 syngeneic mouse treated with a PI3Ka/d inhibitor (AZD8835) |
1.1 | | Ly6c1 | 'K14-Cre-ERT2 / CK1α fl/fl / p53 fl/fl; 4-hydroxytamoxifen; none; 7 day' vs 'K14-Cre-ERT2; none; none' | genotype, irradiate, time | Ablation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin |
-1.1 | | Ly6c1 | 'CEBPa K159R/K298R expression' vs 'wild type CEBPa expression' | genotype | Transcriptome profiling of wild type, K159/298Q- and K159/298R- C/EBPα expressing mouse cells |
1.1 | | Ly6c1 | 'TIMP1 knockout; SARS MA15; 7 day' vs 'TIMP1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1.1 | | Ly6c1 | 'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '4 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
1.1 | | Ly6c1 | '10 day' vs '0 day' | age | Time course analysis of the cardiac transcriptome in the neonatal period |
1.1 | | Ly6c1 | 'Debaryomyces hansenii' at '24 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
1.1 | | Ly6c1 | 'SARS coronavirus MA15' vs 'none' at '1 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1.1 | | Ly6c1 | 'SARS coronavirus MA15' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1.1 | | Ly6c1 | 'inh-alpha/Tag transgenic' vs 'wild type' in 'none' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
1.1 | | Ly6c1 | '2'-fucosyllactose supplementation' vs 'control' in '8 weeks post-ileocecal resection' | diet, treatment | Transcriptomic characterization of the impact of 2'-fucosyllactose supplementation on intestinal adaptation following ileocecal resection. |
1.1 | | Ly6c1 | 'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '4 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1 | | Ly6c1 | 'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
1 | | Ly6c1 | 'Pea3 overexpression' vs 'wild type' | phenotype | Expression analysis of Pea3, Erm and Er81 overexpression in mHypoA-2/12 cell line |
1 | | Ly6c1 | 'Influenza A virus' vs 'mock' in 'interleukin-22' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
1 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NZO/HILtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Ly6c1 | 'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
1 | | Ly6c1 | 'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '4 day' | genotype, infect, time | SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice |
1 | | Ly6c1 | 'anti-mPDL1; anti-mCTLA4; 10 milligram per kilogram' vs 'none' at '14 day' | compound, time | RNAseq of tumor samples from CT26 syngeneic mouse treated with a PD-L1 and CTLA-4 immunotherapy combination |
1 | | Ly6c1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NZO/HILtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Ly6c1 | 'SARS coronavirus MA15' vs 'none' at '7 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
1 | | Ly6c1 | 'PLAT knockout; SARS MA15; 7 day' vs 'PLAT knockout; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
1 | | Ly6c1 | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1 | | Ly6c1 | 'SARS coronavirus MA15 dORF6' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
1 | | Ly6c1 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Ly6c1 | 'SARS coronavirus MA15 lacking full-length E protein' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
1 | | Ly6c1 | 'Il10-/-; Rabgef1 IEC-KO' vs 'wild type genotype' in 'none' | compound, genotype | RNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion |
