8.2 | | Ctse | 'soticlestat; 30 milligram per kilogram' vs 'none' in 'astrocyte; none' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
6.8 | | Ctse | 'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-6.8 | | Ctse | 'soticlestat; 30 milligram per kilogram' vs 'none' in 'neuron; status epilepticus' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
6.6 | | Ctse | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
6.6 | | Ctse | 'status epilepticus' vs 'none' in 'neuron; none' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
6.2 | | Ctse | 'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-6.1 | | Ctse | '365 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
6 | | Ctse | 'CAR deficient; ethanol and ellagic acid' vs 'wild type; ethanol and ellagic acid' | genotype, treatment | Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages |
-5.9 | | Ctse | '180 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
5.9 | | Ctse | 'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
-5.8 | | Ctse | '60 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-5.7 | | Ctse | '90 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-5.7 | | Ctse | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
5.6 | | Ctse | 'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-5.6 | | Ctse | '730 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
5.6 | | Ctse | 'p48-Cre;KrasG12D;Ela-Tgfa' vs 'wild type' | genotype | Transcription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice |
-5.6 | | Ctse | 'status epilepticus' vs 'none' in 'astrocyte; soticlestat; 30 milligram per kilogram' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
5.3 | | Ctse | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Transcription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa |
5.2 | | Ctse | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'biliary-derived proliferative ducts (bilDP)' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
-5.2 | | Ctse | '21 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-5.1 | | Ctse | '30 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
5 | | Ctse | 'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
-5 | | Ctse | 'Porphyromonas gingivalis; hyperlipidemia' vs 'normal' | infect, phenotype | hyperlipidemia impaired innate response |
5 | | Ctse | 'CAR deficient; ethanol' vs 'wild type; ethanol' | genotype, treatment | Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages |
4.9 | | Ctse | 'wild type; mature luminal' vs 'wild type; MaSC/basal' | cell type, genotype | Expression data from sorted control and Pygo2-null mouse mammary stem/basal cells |
-4.8 | | Ctse | 'clear cell sarcoma; Rosa26CreER' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
4.7 | | Ctse | 'Ela-Tgfa' vs 'wild type' | genotype | Transcription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice |
-4.5 | | Ctse | '14 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
4.5 | | Ctse | 'PD1-/-' vs 'wild type genotype' | genotype | Transcription profiling by array of mouse CD8 central memory T-cells derived from spleens of 7-month old PD-1 knockout or wild-type mice |
4.4 | | Ctse | 'T-cell depleted bone marrow transplant' vs 'none' in 'normal' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
4.4 | | Ctse | 'Sap knockout; stimulated with plate-bound alphaCD3 for 30 min' vs 'wild type; stimulated with plate-bound alphaCD3 for 30 min' | genotype, stimulus | Gene expression analysis of double positive T cells from different genotypes, unstimulated or stimulated with plate-bound alphaCD3 for 30 min |
-4.3 | | Ctse | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-4.2 | | Ctse | 'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
4.2 | | Ctse | 'Sap knockout; none' vs 'wild type; none' | genotype, stimulus | Gene expression analysis of double positive T cells from different genotypes, unstimulated or stimulated with plate-bound alphaCD3 for 30 min |
4.2 | | Ctse | 'transgenic' vs 'wild type' in '121 day; 129Sv' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
4.2 | | Ctse | 'Elk/Sap double knockout; stimulated with plate-bound alphaCD3 for 30 min' vs 'wild type; stimulated with plate-bound alphaCD3 for 30 min' | genotype, stimulus | Gene expression analysis of double positive T cells from different genotypes, unstimulated or stimulated with plate-bound alphaCD3 for 30 min |
-4.1 | | Ctse | 'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
-4.1 | | Ctse | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
4.1 | | Ctse | 'Kras G12D' vs 'wild type' | genotype | Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells |
4.1 | | Ctse | 'Elk/Sap double knockout; none' vs 'wild type; none' | genotype, stimulus | Gene expression analysis of double positive T cells from different genotypes, unstimulated or stimulated with plate-bound alphaCD3 for 30 min |
4 | | Ctse | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
4 | | Ctse | 'CXCR4 overexpression' vs 'wild type' | phenotype | Transcription profiling by array of resting memory OT-I T_CXCR4 or OT-I T_Control cells isolated from the spleen 90 days following DC vaccination |
4 | | Ctse | 'spontaneous lung tumor' vs 'normal' | disease state, disease | Transcription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer |
-3.9 | | Ctse | 'Porphyromonas gingivalis; hyperlipidemia' vs 'Porphyromonas gingivalis; normal' | infect, phenotype | hyperlipidemia impaired innate response |
3.9 | | Ctse | 'high fat diet' vs 'regular chow diet' in 'liver-specific Pit1 knockout' | diet, genotype | Transcription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet |
3.8 | | Ctse | '14 days P. chabaudi infected' vs 'uninfected' in 'intact male' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-3.8 | | Ctse | 'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
3.8 | | Ctse | 'CAR deficient; ethanol and trans-resveratrol' vs 'wild type; ethanol and trans-resveratrol' | genotype, treatment | Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages |
3.7 | | Ctse | 'interleukin-13 (Mus musculus); 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
3.6 | | Ctse | '14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized male' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
3.6 | | Ctse | 'p150 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA' | RNA interference | RNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells |
3.6 | | Ctse | 'hepatocyte-specific Pten knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
3.6 | | Ctse | 'CAR deficient; control' vs 'wild type; control' | genotype, treatment | Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages |
3.5 | | Ctse | '16 day' vs '0 day' | age | Gene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26) |
3.5 | | Ctse | 'Eed knockout' vs 'control' | genotype | Expression profiling of primary wild type (WT), Ezh2-null and Eed-null murine MLL-AF9 AML |
3.4 | | Ctse | 'BCL6 knockout and inducible BACH2 overexpression' vs 'wild type and inducible BACH2 overexpression' | genotype | Gene expression profile of BCR-ABL1 transformed pre-B mouse cells from BCL6 knockout after inducible overexpression of Bach2 |
3.4 | | Ctse | 'normobaric hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo. |
3.4 | | Ctse | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
3.4 | | Ctse | 'Nippostrongylus brasiliensis' vs 'none' | infect | RNAseq of small intestinal epithelium extracted from mice infected with Nippostrongylus brasiliensis |
-3.4 | | Ctse | 'megakaryocyte' vs 'hematopoietic stem cell' | cell type | Transcription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells |
3.4 | | Ctse | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-3.4 | | Ctse | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
3.3 | | Ctse | 'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens |
3.3 | | Ctse | '5XFAD transgenic' vs 'wild type' | genotype | Transcription profiling by array of microglia purified from wild type and TREM2 deficient microglia in a mouse model of Alzheimer's disease |
-3.1 | | Ctse | 'dextran sodium sulfate' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion |
3.1 | | Ctse | '14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-3.1 | | Ctse | 'reduced expression of miR-25' vs 'wild type' | phenotype | Transcription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice |
-3 | | Ctse | 'Il10-/-; Rabgef1 IEC-KO' vs 'wild type genotype' in 'none' | compound, genotype | RNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion |
-3 | | Ctse | 'Col1a1-tetO-MLL/ENL' vs 'wild type' in 'hematopoietic stem cell' | cell type, genotype | Transcription profiling by high throughput sequencing of hematopoietic stem cells from a conditional-inducible mouse model of the MLL-ENL fusion oncogene |
3 | | Ctse | 'glioblastoma multiforme' vs 'normal' | disease | Analysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus. |
3 | | Ctse | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
3 | | Ctse | 'Cebpa K/K mutant' vs 'wild type' | genotype | Transcription profiling by array of mouse LSK hematopoietic stem cells from Cebpa K/K, K/L, and L/L knock-in mutants |
3 | | Ctse | 'Cebpa K/L mutant' vs 'wild type' | genotype | Transcription profiling by array of mouse LSK hematopoietic stem cells from Cebpa K/K, K/L, and L/L knock-in mutants |
2.9 | | Ctse | '14 days P. chabaudi infected' vs 'uninfected' in 'intact female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-2.8 | | Ctse | 'Notch 1 and 2 null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
2.8 | | Ctse | '26 day' vs '0 day' | age | Gene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26) |
-2.8 | | Ctse | 'induce erythroid differentiation' vs 'none' in 'wild type' | genotype, stimulus | Transcription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor |
2.8 | | Ctse | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-2.8 | | Ctse | 'liver-specific Pit1 knockout' vs 'wild type genotype' in 'regular chow diet' | diet, genotype | Transcription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet |
-2.7 | | Ctse | 'Rel -/-; Nfkb1-/-; CD4Cre Rela fx/fx' vs 'wild type genotype' | genotype | RNA-seq of CD8 single positive thymocytes from WT and Rela fx/fx CD4Cre Nfkb1KO RelKO mice. |
2.7 | | Ctse | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
2.7 | | Ctse | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
2.7 | | Ctse | 'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
2.7 | | Ctse | 'transgenic' vs 'wild type' in '111 day; 129Sv' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
-2.7 | | Ctse | 'p38alpha null' vs 'wild type genotype' in 'embryonic day 13.5' | developmental stage, genotype | Transcription profiling of mouse embryonic day 13.5 and 15.5 fetal livers lacking p38alpha, a mitogen-activated kinase that controls inflammatory responses and cell proliferation |
-2.7 | | Ctse | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-2.6 | | Ctse | 'Psen 1 and 2 null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
-2.6 | | Ctse | 'RBPjk null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
2.6 | | Ctse | 'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
2.6 | | Ctse | 'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; prostaglandin E2; 1 micromolar' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.6 | | Ctse | 'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; lipopolysaccharide; 10 nanogram per milliliter' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.6 | | Ctse | 'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout' | compound, genotype, infect | 4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies |
2.6 | | Ctse | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-2.6 | | Ctse | 'estradiol' at '30 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling by array of G1E cells during time course treatment with estradiol. |
2.6 | | Ctse | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
2.6 | | Ctse | 'chemical hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo. |
-2.6 | | Ctse | 'acute DSS-induced colitis; 1x DSS, no recovery' vs 'none; none' | clinical treatment, disease | Transcription profiling by array of colon tissues isolated from mice with acute and chronic dextran sodium sulphate (DSS)-induced colitis |
2.6 | | Ctse | '130 week' vs '13 week' in 'spleen' | age, organism part | Transcription profiling by array of liver, lung, spleen and kidney from young and old mice. |
-2.5 | | Ctse | 'Kit ligand' vs 'none' in 'wasp knockout' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
2.5 | | Ctse | 'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.5 | | Ctse | 'Kin-' vs 'wild type' in 'cAMP' at '24 hour' | compound, genotype, time | Transcription profiling by array of mouse S49 cells mutant for Kin after treatment with cAMP |
-2.5 | | Ctse | 'expanded on HUVEC and m5GF in the presence of mD1R for 7 days' vs 'control' | treatment | Expression data from cultured c-Kit+Sca-1+Lin- (KSL)cells |
-2.5 | | Ctse | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-2.4 | | Ctse | 'Il10-/-' vs 'wild type genotype' in 'none' | compound, genotype | RNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion |
2.4 | | Ctse | 'fenofibrate diet' vs 'control diet' | diet | Comparative transcriptomics and metabolomic analysis of fenofibrate and fish oil treatments in mice |
2.4 | | Ctse | 'MEF2C/D knockout' vs 'wild type genotype' in 'primary cell line; none' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.4 | | Ctse | 'Cbs knockout' vs 'wild type' | genotype | Gene expression profile of CD4-positive T cells from mouse Cbs knockout |
-2.4 | | Ctse | 'oral hard palate epithelium' vs 'tail skin epithelium' | organism part | Transcriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression |
2.4 | | Ctse | 'dinitrofluorobenzene' vs 'control' in 'Cnr1 -/- /Cnr2 -/-' | compound, genotype | Transcription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity |
-2.4 | | Ctse | 'Klf5 knockout' vs 'wild type Klf5' | genotype | Expression data from conditional Klf5 knockout Pten-null mouse prostates |
2.4 | | Ctse | 'transgenic' vs 'wild type' in '101 day; 129Sv' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
-2.4 | | Ctse | 'lipopolysaccharide' vs 'none' in 'bone marrow; wild type' | cell type, compound, genotype | Transcription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice |
2.4 | | Ctse | 'Ghrh-KO' vs 'wild type' | genotype | Gene expression in liver tissue from Ghrh-KO and normal (wild-type) mice |
-2.3 | | Ctse | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD8-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
2.3 | | Ctse | 'embryo transfer' vs 'no embryo transfer' | stimulus | RNA-seq of whole mouse placentas at E10.5 comparing C57Bl/6 male conceptuses that had undergone blastocyst transfer to non-transferred C57Bl/6 male conceptuses |
2.3 | | Ctse | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-2.3 | | Ctse | 'Col1a1-tetO-MLL/ENL' vs 'wild type' in 'precursor for granulocyte-macrophage progenitor cell' | cell type, genotype | Transcription profiling by high throughput sequencing of hematopoietic stem cells from a conditional-inducible mouse model of the MLL-ENL fusion oncogene |
2.3 | | Ctse | 'TMEV infected' at '196 day' vs 'mock control' at '196 day' | disease, time | Transcription profiling of mouse spinal cord from mock-infected and Theilers murine encephalomyelitis (TME)-virus infected animals - time series |
-2.3 | | Ctse | 'lymphocytic choriomeningitis virus WE' vs 'normal' | disease | Transcription profiling by array of lymphocytic choriomeningitis virus-strain WE (LCMV-WE) infected mice versus naive mice. |
2.3 | | Ctse | 'TMEV infected' at '98 day' vs 'mock control' at '98 day' | disease, time | Transcription profiling of mouse spinal cord from mock-infected and Theilers murine encephalomyelitis (TME)-virus infected animals - time series |
2.3 | | Ctse | 'Hnf4a conditional knockout' vs 'wild type genotype' | genotype | Transcription profiling of mouse conditional intestinal epithelial Hnf4Ialpha knockout to investigate the role of HNF4alpha in the adult colon |
2.3 | | Ctse | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
2.3 | | Ctse | 'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
2.2 | | Ctse | '7 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
2.2 | | Ctse | 'Tg4510 genotype' vs 'wild type' | genotype, phenotype | Expression data from Tg4510 and Wild-type mice after AAVTFEB injection |
-2.2 | | Ctse | 'renin-expression' vs 'control' | phenotype | Expression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein. |
-2.2 | | Ctse | 'germanium(2+)' vs 'normal chow' | diet | Transcription profiling by array of mouse treated with normal chow or that containing 0.15% germanium dioxide for four months |
-2.2 | | Ctse | 'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-2.1 | | Ctse | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
2.1 | | Ctse | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
2.1 | | Ctse | 'granulocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
2.1 | | Ctse | 'Influenza A virus' vs 'none' | infect | RNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals |
2.1 | | Ctse | 'chronic pancreatitis' vs 'control' | disease | Pancreatic gene expression associated with cerulein induced chronic pancreatitis in mice |
2.1 | | Ctse | 'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar' | compound, genotype | Overexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment |
-2.1 | | Ctse | 'SOD1 transgenic' vs 'wild type' at 'day 100' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
-2.1 | | Ctse | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-2 | | Ctse | 'Kit ligand' vs 'none' in 'wild type' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
2 | | Ctse | '6 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
2 | | Ctse | 'TMEV infected' at '42 day' vs 'mock control' at '42 day' | disease, time | Transcription profiling of mouse spinal cord from mock-infected and Theilers murine encephalomyelitis (TME)-virus infected animals - time series |
-2 | | Ctse | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
2 | | Ctse | 'Plasmodium chabaudi infection' vs 'no infection' in 'vaccination' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
2 | | Ctse | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
-2 | | Ctse | 'Rb^{lox/lox}; p130^{lox/lox}; p107+/-' vs 'wild type' | genotype | Transcription profiling by array of livers from the mouse model of human hepatocellular carcinoma |
-2 | | Ctse | '6 day' vs '0 day' | time | Transcription profiling by array of mouse colon tissues under dextran sodium sulphate induction for 2, 4 and 6 days against uninduced controls at day 0 |
2 | | Ctse | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-2 | | Ctse | 'SMRT shRNA' vs 'none' in 'CpG' at '6 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-1.9 | | Ctse | 'Plasmodium berghei' vs 'none' in 'none' | compound, infect | Transcription profiling by array of mouse blood infected with Plasmodium berghei after treatment with activated charcoal |
1.9 | | Ctse | '7 days P. chabaudi infected' vs 'uninfected' in 'intact male' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
1.9 | | Ctse | 'unilateral ureteral obstruction' vs 'sham' in 'wild type' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
1.9 | | Ctse | 'smoke; 1500 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
1.9 | | Ctse | 'MFP2 knockout' vs 'wild type' | genotype | Defining the microglia transcriptome in multifunctional protein-2 deficient mice |
-1.8 | | Ctse | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
1.8 | | Ctse | '5 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
1.8 | | Ctse | 'dexamethasone; 100 nanomolar; interferon gamma' vs 'none' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
1.8 | | Ctse | 'Sall1 deficient microglia' vs 'wild type microglia' | genotype, phenotype | RNA sequencing of microglia sorted form tamoxifen treated Sall1CreER/fl and control Sall1fl/fl mice |
-1.8 | | Ctse | 'hematopoietic stem cell and hematopoietic multipotent progenitor cell' vs 'common myeloid progenitor' | cell type | Transcription profiling by high throughput sequencing between multipotent hematopoietic stem progenitor cells LS+K) and myeloid committed cells (LS−K) of the mouse bone marrow |
-1.8 | | Ctse | 'polarized with E coli lipopolysacharide and INF-gamma' vs 'untreated' | compound, treatment | Expression data from polarized macrophages: effect of p53 |
1.8 | | Ctse | 'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
-1.8 | | Ctse | 'CpG; 6 hour' vs 'none; 0 hour' in 'none' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-1.7 | | Ctse | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
-1.7 | | Ctse | 'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1.7 | | Ctse | 'Kin-' vs 'wild type' in 'cAMP' at '6 hour' | compound, genotype, time | Transcription profiling by array of mouse S49 cells mutant for Kin after treatment with cAMP |
1.7 | | Ctse | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.7 | | Ctse | 'Staphylococcus aureus Sanger476; 6 hour' vs 'none; 0 hour' in 'C57BL/6J' | infect, strain, time | Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans |
-1.7 | | Ctse | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '14 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
-1.7 | | Ctse | 'estradiol' at '21 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling by array of G1E cells during time course treatment with estradiol. |
1.7 | | Ctse | 'ATF3 -/-' vs 'wild type' in '10 nanogram per milliliter; lipopolysaccharide' at '1 hour' | compound, genotype, time | Transcription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide |
1.7 | | Ctse | 'Plasmodium berghei ANKA' at '7 day' vs 'none' at '0 day' in 'none' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.7 | | Ctse | 'erythroblast' vs 'hematopoietic stem cell' | cell type | Transcription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells |
1.7 | | Ctse | 'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 70 day' vs 'control; D2.B6-Chr7 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.7 | | Ctse | 'untreated; Csf2rb-/-' vs 'untreated; wild type' | clinical history, genotype | Mouse GM-CSF-related alveolar macrophage genome-wide expression data |
-1.7 | | Ctse | 'DKO' vs 'wild type' | genotype | Transcription profiling by array of wild type and Hdac1 and 2 knockout lymphocytes |
1.6 | | Ctse | 'diphtheria toxin; 30 nanogram per gram' vs 'none' | stimulus | RNA-seq of mouse brain tissue repopulating microglia in response to traumatic brain injury |
-1.6 | | Ctse | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-1.6 | | Ctse | 'doxycicline-mediated expression of c-Jun' vs 'control' | phenotype | Transcription profiling by array of mouse whole bone marrow after c-Jun induction |
-1.6 | | Ctse | 'one year after pulmonary macrophage transplantation; Csf2rb-/-' vs 'untreated; Csf2rb-/-' | clinical history, genotype | Mouse GM-CSF-related alveolar macrophage genome-wide expression data |
1.6 | | Ctse | 'dinitrofluorobenzene' vs 'control' in 'wild type' | compound, genotype | Transcription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity |
1.6 | | Ctse | 'Albumin Cre+/-;Hnf4a fl/fl' vs 'wild type genotype' | genotype | Transcription profiling by array of liver-specific Hnf4alpha knock-out mice |
-1.6 | | Ctse | 'SMRT shRNA' vs 'none' in 'none' at '0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-1.6 | | Ctse | 'Tet2 knockout' vs 'wild type' in 'hematopoietic stem cell' | cell type, genotype | Transcription profiling by high throughput sequencing of bone marrow stem and progenitor cells from Tet2 depleted mice |
1.6 | | Ctse | 'PgrCre/+ Foxa2flox/flox' vs 'wild type' | genotype | Identification of candidate FOXA2-regulated genes in the adult mouse uterus |
-1.6 | | Ctse | 'induction of polymicrobial sepsis' vs 'control' at '72 hour' in '20 to 24 month mice' | age, time, treatment | Aged Mice are Unable to Mount an Effective Myeloid Response to Sepsis |
-1.5 | | Ctse | 'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out' | genotype, infect | Comparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice |
1.5 | | Ctse | 'high GLUT1 expression' vs 'low GLUT1 expression' in 'wild type genotype' | genotype, phenotype | RNA-seq analysis of normoxic and hypoxic tumor-associated macrophages from wild type or REDD1 knockout mice |
1.5 | | Ctse | '4 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
1.5 | | Ctse | '3 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
1.5 | | Ctse | 'Tgfbeta 1 ligand 0.04 nanogram per milliliter' vs 'none' | compound | Expression data from intestinal organoids altered for Tgfbeta signaling |
1.5 | | Ctse | 'interferon gamma' vs 'none' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
-1.5 | | Ctse | 'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA' | compound, infect, sampling time point | RNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM) |
1.5 | | Ctse | 'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 30 day' vs 'control; D2.B6-Chr7 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.5 | | Ctse | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
1.5 | | Ctse | 'Yin Yang 1 adipose tissue specific deletion' vs 'wild type phenotype' | phenotype | Brown fat-specific YY1 deficiency effect on subcutaneous white adipose tissue |
1.5 | | Ctse | '130 week' vs '13 week' in 'lung' | age, organism part | Transcription profiling by array of liver, lung, spleen and kidney from young and old mice. |
1.5 | | Ctse | 'wild type; treated with angiotensin II' vs 'wild type; vehicle' | genotype, treatment | Effect of Hypertension of Dendritic Cell Gene Expression |
1.4 | | Ctse | 'lung carcinoma' vs 'normal' in 'lung cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-1.4 | | Ctse | 'interferon gamma; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1.4 | | Ctse | 'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'C57BL/6J' | infect, strain, time | Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans |
-1.4 | | Ctse | 'estradiol' at '14 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling by array of G1E cells during time course treatment with estradiol. |
1.4 | | Ctse | 'high fat' vs 'chow' in 'NZO/HILtJ' | diet, strain | Transcription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ |
1.4 | | Ctse | '7 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
1.4 | | Ctse | 'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 30 day' vs 'control; D2.B6-Chr19 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.4 | | Ctse | 'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.4 | | Ctse | 'ATF3 -/-' vs 'wild type' in '10 nanogram per milliliter; lipopolysaccharide' at '2 hour' | compound, genotype, time | Transcription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide |
1.4 | | Ctse | 'intestinal smooth muscle culture supernatant' vs 'none' in 'organoid culture without Noggin (ER medium)' | growth condition, stimulus | RNA-seq of small intestinal organoids treated with the control medium ENR (EGF, Noggin, R-spondin1) in the presence or absence of muscle supernatant |
1.4 | | Ctse | 'Mycobacterium tuberculosis; DBA/2J congenic; 30 day' vs 'control; DBA/2J congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
-1.4 | | Ctse | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'classical monocyte' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
1.4 | | Ctse | 'human fast food diet' vs 'control diet' | diet | Transcription profiling by array of mice fed on human cafeteria diet, human fast food diet, or chimpanzee diet |
1.4 | | Ctse | 'metaphase II oocyte' vs 'germinal vesicle oocyte' | cell type | Transcription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming |
-1.4 | | Ctse | 'side population cells' vs 'main population cells' in 'bone marrow' | cell type, organism part | Gene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow |
1.4 | | Ctse | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1.4 | | Ctse | '110 week' vs '8 week' | age | Transcription profiling by array of CD11C+ splenic dendritic cells from young (8 weeks) and old (110 weeks) mice treated with Poly I:C for 4 hours |
-1.4 | | Ctse | 'RAW264.7 macrophage cell line; control' vs 'bone marrow macrophage; control' | cell type, growth condition | Transcription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line |
-1.3 | | Ctse | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
1.3 | | Ctse | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2; Il22-/-' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
1.3 | | Ctse | 'high GLUT1 expression' vs 'low GLUT1 expression' in 'Ddit4 knockout' | genotype, phenotype | RNA-seq analysis of normoxic and hypoxic tumor-associated macrophages from wild type or REDD1 knockout mice |
-1.3 | | Ctse | 'Runx1 knockdown; none' vs 'wild type; none' | genotype, stimulus | Transcription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor |
-1.3 | | Ctse | 'cecal ligation and puncture surgery; PPTA knockout' vs 'cecal ligation and puncture surgery; wild type' | clinical treatment, genotype | Gene expression profile in lung tissue 8 h after inducing polymicrobial sepsis in preprotachykinin-A (PPTA) knockout mice and wild type |
1.3 | | Ctse | 'ATF3 -/-' vs 'wild type' in 'none' at '0 hour' | compound, genotype, time | Transcription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide |
-1.3 | | Ctse | 'Dcrfx/fx;MisCre' vs 'wild type' in '5 day' | age, genotype | Transcription profiling of testis from wild type mice and mice with a Sertoli-specific ablation of Dicer |
-1.3 | | Ctse | 'Ngn3-expressing cell' vs 'Ngn3-null cell' | cell type | Transcriptional profiling of Ngn3-dependent pancreatic endocrine differentiation at E15.5 |
1.3 | | Ctse | 'Nix knock out' vs 'wild type' | genotype | Transcription profiling by array of spleens from mice with Nix knocked out. |
1.3 | | Ctse | 'L-Pex5 knock-out' vs 'wild type' | genotype | Transcription profiling by array of liver from L-Pex5 knock-out mice |
1.3 | | Ctse | 'cecal ligation and puncture surgery' vs 'sham surgery' in 'PPTA knockout' | clinical treatment, genotype | Gene expression profile in lung tissue 8 h after inducing polymicrobial sepsis in preprotachykinin-A (PPTA) knockout mice and wild type |
-1.3 | | Ctse | 'Vldlr knockout' vs 'wild type genotype' in 'house dust mite' | genotype, treatment | Transcription profiling by array of lungs of Vldlr-/- mice and wild type (WT) B6129SF2/J mice that had received intranasal house dust mite (HDM) challenges to induce experimental asthma or saline |
1.3 | | Ctse | 'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
-1.3 | | Ctse | 'CD4-CRE+ (PPAR g null)' vs 'wild type genotype' at '2 day' | genotype, time | Transcription profiling by array of mouse Peroxisome proliferator-activated receptor g (PPARg) null CD4+ T cells after treatment with dextran-sodium sulfate for 2 or 7 days to induce colitis |
-1.3 | | Ctse | 'eIF6+/-' vs 'wild type genotype' | genotype | RNA-seq of liver biopsies of eIF6 wild type and eIF6 heterozygous mice |
-1.2 | | Ctse | 'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
1.2 | | Ctse | 'recombinant Fgf10 (1 milligram per milliliter)' vs 'none' in 'wild type genotype' | genotype, stimulus | Role of Fgf10 signalling in regulation of gene expression in developing mouse cortex |
-1.2 | | Ctse | 'Cd1d homozyous knockout' vs 'wild type genotype' in 'α-GalCer; 2 microgram' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
-1.2 | | Ctse | 'TRIM28(flox/flox):Mx1Cre' vs 'TRIM28(flox/flox)' in 'CD71(hi)TER119-' | genotype, phenotype | Transcription profiling by high throughput sequencing of bone marrow immature erythroid cells from Trim28flox/flox:TgMx1Cre congenic mice |
-1.2 | | Ctse | 'Staphylococcus aureus Sanger476; 4 hour' vs 'none; 0 hour' in 'C57BL/6J' | infect, strain, time | Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans |
1.2 | | Ctse | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.2 | | Ctse | 'Trem2 knockout, 5XFAD transgenic' vs 'wild type' | genotype | Transcription profiling by array of microglia purified from wild type and TREM2 deficient microglia in a mouse model of Alzheimer's disease |
-1.2 | | Ctse | 'Het (Q175) knock-in' vs 'wild type' in 'skin' | genotype, organism part | Transcriptome profiling in knock-in mouse models of Huntington's disease [AllelicSeries_6month_TissueSurvey_mRNA] |
-1.2 | | Ctse | 'promyelocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
1.2 | | Ctse | 'Ffar3 knockout' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of pancreatic islets isolated from free fatty acid receptor 3 knockout (Ffar3 KO) and wild type (Ffar3 WT) male mice |
-1.2 | | Ctse | '19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '5 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
-1.2 | | Ctse | 'CpG ODN' vs 'PBS' at '4 hour' | compound, time | Transcription profiling by array of mouse vaginal samples following adjuvant treatment |
1.2 | | Ctse | 'perfluorooctanoic acid; 10 milligram per kilogram per day' vs 'none' in 'lung' | block, compound, organism part | Transcription profiling of lung and liver from low and high dose Perfluorooctanoic Acid exposed fetuses |
-1.1 | | Ctse | 'Runx1 P1-GFP::P2-hCD4/+' vs 'wild type' | genotype | RUNX1B expression distinguishes megakaryocytic and erythroid lineage fate in adult hematopoiesis |
1.1 | | Ctse | 'IL17A homozygous knockout' vs 'wild type genotype' in 'ileum' | genotype, organism part | RNAseq analysis of colon and ileum tissue from naive wild type, MR1-/- and IL-17A-/- mice |
1.1 | | Ctse | 'AZD8835; 50 milligram per kilogram' vs 'none' at '14 day' | compound, time | RNAseq of tumor samples from CT26 syngeneic mouse treated with a PI3Ka/d inhibitor (AZD8835) |
1.1 | | Ctse | 'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |
1.1 | | Ctse | 'RBM20 antisense oligonucleotide' vs 'none' in 'wild type genotype' | RNA interference, genotype | Heart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF) |
-1.1 | | Ctse | 'Porphyromonas gingivalis; normal' vs 'normal' | infect, phenotype | hyperlipidemia impaired innate response |
1.1 | | Ctse | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NZO/HILtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.1 | | Ctse | 'KrasG12D' vs 'wild type' | genotype | An oncogenic Kras expression signature identified by cross-species |
1.1 | | Ctse | 'FVBNCr; RML infected' at '20 week' vs 'FVBNCr; uninfected' at '20 week' | strain, time, treatment | Transcription profiling of mouse brain infected with prions in eight mouse-prion strain combinations in a systems approach to the study of prion disease |
1.1 | | Ctse | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.1 | | Ctse | 'Escherichia coli O18:K1:H7; 6 hour' vs 'none; 0 hour' in 'C57BL/6J' | infect, strain, time | Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans |
1.1 | | Ctse | 'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day' | infect, strain, time | Transcription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days |
1.1 | | Ctse | 'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector' | genotype | RNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice |
1.1 | | Ctse | 'homozygous Cav1.1 mutant' vs 'Cav1.1 wild type' in 'embryonic day 14.5' | developmental stage, genotype | Microarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels |
-1.1 | | Ctse | 'arsenic' vs 'water' | compound | Transcription profiling by array of mice exposed to arsenic and iron by drinking water |
-1.1 | | Ctse | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1.1 | | Ctse | 'plasmacytoid dendritic cell; Ifnar1 knock out; specific pathogen free' vs 'plasmacytoid dendritic cell; wild type genotype; specific pathogen free' | cell type, genotype, growth condition | RNA sequencing of primary isolated unstimulated murine splenic DC1 and DC2 from specific pathogen free (SPF), Germ free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice |
1.1 | | Ctse | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.1 | | Ctse | 'none; ; CHIP knockout' vs 'none; ; wild type' | compound, genotype | Expression data from DOX(doxorubicin) -treated wild type or CHIP knockout C57BL/6J mice at day 5 |
1.1 | | Ctse | 'Ezh2 knockout' vs 'control' | genotype | Expression profiling of secondary wild type (WT) and Ezh2-null murine MLL-AF9 AML |
-1.1 | | Ctse | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
-1.1 | | Ctse | 'IL-1R knockout' vs 'wild type' in 'Staphylococcus aureus cutaneous infection' | disease, genotype | Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice |
1.1 | | Ctse | 'PS2APP transgenic' vs 'non transgenic' in 'microglia cell' at '7 month' | age, cell type, genotype | Transcription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model |
1 | | Ctse | 'MYC siRNA' vs 'non-targeting siRNA' | RNA interference | RNA-SEQ analysis of KMC murine pancreatic ductal adenocarcinoma (PDAC) cell line upon siRNA depletion of MYC, KRas or Miz1 (aka Zbtb17) |
-1 | | Ctse | 'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
1 | | Ctse | 'high fat' vs 'chow' in 'WSB/EiJ' | diet, strain | Transcription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ |
-1 | | Ctse | 'Cbfb knockout' vs 'control of Cbfb knockout' | genotype | Transcription profiling by array of Mus musculus expressing Cbfb-MYH11 |
1 | | Ctse | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Ctse | 'estradiol' at '7 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling by array of G1E cells during time course treatment with estradiol. |
1 | | Ctse | '4 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
1 | | Ctse | 'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2' | genotype, irradiate | RNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy |
1 | | Ctse | '2 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
-1 | | Ctse | 'induce erythroid differentiation' vs 'none' in 'Runx1 knockdown' | genotype, stimulus | Transcription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor |
1 | | Ctse | 'transgenic' vs 'wild type' in '160 day; C57BL/6' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
-1 | | Ctse | 'IEC-specific HDAC3 deletion' vs 'floxed HDAC3 (wild type)' | genotype | Transcription profiling by array of intestinal epithelial cells (IECs) from mice with IEC-specific HDAC3 deletion against wild type controls |
1 | | Ctse | 'db/db' vs 'wild type genotype' in 'control miRNA; re-fed' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
1 | | Ctse | 'chimpanzee diet' vs 'control diet' | diet | Transcription profiling by array of mice fed on human cafeteria diet, human fast food diet, or chimpanzee diet |
1 | | Ctse | 'Tet3homozygous knock out' vs 'wild type genotype' in 'Ly6C-positive' | genotype, phenotype | RNA-seq of primary mouse monocytes from miR-150 knockout and Tet3 knockout mice compared to wild type controls |
1 | | Ctse | 'human cafeteria diet' vs 'control diet' | diet | Transcription profiling by array of mice fed on human cafeteria diet, human fast food diet, or chimpanzee diet |
1 | | Ctse | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
1 | | Ctse | 'interferon gamma' vs 'none' in 'dexamethasone; 100 nanomolar' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
1 | | Ctse | 'thermal injury' vs 'none' | injury | Microarray profiling of post-injury and uninjured mouse lung neutrophils from a thermal injury model |
1 | | Ctse | 'TGF-beta; 1.5 nanogram per milliliter' vs 'control' | compound | TGF beta Dosage Experiment |
-1 | | Ctse | 'effluent of advance treatment by quaternized magnetic microsphere' vs 'purified water' | environmental stress | Transcription profiling by array of M. musculus male liver mice cells to investigate risks in a drinking water plant |
1 | | Ctse | '14 month; QH2; heart' vs '14 month; control; heart' | age, compound, organism part | Coenzyme Q10-dependent gene expression in SAMP1 mice tissues |
