ensmusg00000024806 (Mlana)

mus musculus

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Mus musculus
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Showing 11 experiments:
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Created with Highcharts 6.2.0arcuate nucleus of hypothalamusbraincentral neural epitheliumcerebellumcolondorsal control neural epitheliumdorsal raphe nucleushearthippocampal formationkidneylateral nasal prominencelateral prominence neural epitheliumliverlungmandibular archmaxillary archmedial nasal prominencemuscle tissueolfactory pitskeletal muscle tissuespleentestisthymuszone of skin
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Mammalian Kaessmann
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9 in 3 strains - C57BL/6
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9
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3 Soumillon et al
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14 - embryonic day 10.5
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4 Bonthuis et al - C57BL/6J
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Proteomics
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Transcriptomics
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-6.1
1.1
5.3
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.3308 × 10-6-6.1
Mlana'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
2.4911 × 10-115.3
Mlana'uterine-specific Tsc2-null' vs 'wild type' in 'intact'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
4.7823 × 10-104.8
Mlana'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
4.2765 × 10-64.5
Mlana'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
2.4744 × 10-84.4
Mlana'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
2.231 × 10-73.9
Mlana'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
8.5585 × 10-3-3.7
Mlana'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.1561 × 10-23.4
Mlana'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.8432 × 10-2-3.3
Mlana'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.0437 × 10-33.2
Mlana'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.6125 × 10-6-3.1
Mlana'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
5.8415 × 10-33.1
Mlana'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
7.8898 × 10-33.1
Mlana'21 percent oxygen, 37 degree Celsius, no serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
3.6949 × 10-20-3
Mlana'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
1.4005 × 10-73
Mlana'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
4.937 × 10-7-3
Mlana'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
2.3016 × 10-23
Mlana'NeuroD1 conditional knockout' vs 'control' in 'retina' at 'Zeitgeber time 20'genotype, organism part, sampling time pointGene expression profile of retina and pineal gland of NeuroD1 conditional knockout mice
Adjusted p-valueLog2-fold change
1.2204 × 10-62.9
Mlana'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype'genotypeTranscription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy
Adjusted p-valueLog2-fold change
3.3623 × 10-62.8
Mlana'LDB1 knock-down' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
2.7894 × 10-42.8
Mlana'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
3.1286 × 10-32.8
Mlana'Nippostrongylus brasiliensis' vs 'none'infectRNAseq of small intestinal epithelium extracted from mice infected with Nippostrongylus brasiliensis
Adjusted p-valueLog2-fold change
2.087 × 10-2-2.8
Mlana'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.1229 × 10-92.7
Mlana'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
4.7849 × 10-7-2.7
Mlana'oral hard palate epithelium' vs 'tail skin epithelium'organism partTranscriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression
Adjusted p-valueLog2-fold change
4.6351 × 10-32.4
Mlana'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.7953 × 10-4-2.3
Mlana'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
7.6416 × 10-142.1
Mlana'human-Mfn2-overexpressing (Mfn2wt)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.1715 × 10-62.1
Mlana'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
2.3513 × 10-22.1
Mlana'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
2.4156 × 10-8-2
Mlana'doxycycline; 200 nanogram per milliliter; neoplasm; 12 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
2.2733 × 10-2-2
Mlana'30 month' vs '5 month' in 'male'age, block, sexExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Adjusted p-valueLog2-fold change
8.564 × 10-51.9
Mlana'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
1.0117 × 10-21.9
Mlana'ERRalpha null mutant' vs 'wild type genotype'genotypeTranscription profiling of mouse hearts from mutants lacking estrogen-related receptor alpha (ERRalpha), a nuclear receptor
Adjusted p-valueLog2-fold change
1.3409 × 10-2-1.9
Mlana'dmrt1 knockout' vs 'wild type' in 'C57BL/6'genotype, strainDmrt1 (doublesex and mab-3 related transcription factor 1) conditional knockout expression analysis of E15.5 testes.
Adjusted p-valueLog2-fold change
3.2297 × 10-41.8
Mlana'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
6.3762 × 10-41.8
Mlana'E2f1, E2f2, E2f3 triple knockout' vs 'control' at 'neonate'developmental stage, genotypeExpression data from lenses triply deficient for E2F1, E2F2, and E2F3 transcription factors
Adjusted p-valueLog2-fold change
4.5078 × 10-2-1.8
Mlana'14 month; Q10; heart' vs '14 month; control; heart'age, compound, organism partCoenzyme Q10-dependent gene expression in SAMP1 mice tissues
Adjusted p-valueLog2-fold change
2.7041 × 10-101.7
Mlana'human-Mfn2-overexpressing (Mfn2wt)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
5.3292 × 10-8-1.7
Mlana'primary hair placode keratinocyte' vs 'interfollicular epidermal keratinocyte'cell typeTranscription profiling of mouse primary hair placode keratinocytes compared to interfollicular epidermal keratinocytes
Adjusted p-valueLog2-fold change
9.4476 × 10-85-1.6
Mlana'BAG6 homozygous knockout' vs 'wild type genotype'genotypeTranscription profiling of B16V mouse melanoma cells after BAG6 knockout to study impacts on extracellular vesicle mRNA cargo
Adjusted p-valueLog2-fold change
3.9637 × 10-3-1.6
Mlana'high fat diet' vs 'chow diet' in 'SHP knockout'genotype, growth conditionTranscription profiling of small heterodimer partner deficiency (SHP) knockout mice heart
Adjusted p-valueLog2-fold change
5.9862 × 10-31.6
Mlana'expression of a dominant negative form of MCU' vs 'wild type' in 'adult'developmental stage, phenotypemRNA Expression Changes Induced by Myocardial MCU Inhibition
Adjusted p-valueLog2-fold change
3.1567 × 10-3-1.5
Mlana'doxycycline; no induction of Sp1 expression' vs 'none; wild type human Sp1 expression'compound, genotypeTranscription profiling of mouse hematopoietic Baf-3 cells inducibly expressing transcription factor Sp1
Adjusted p-valueLog2-fold change
1.8676 × 10-2-1.5
Mlana'high fat diet' vs 'chow diet' in 'wild type'genotype, growth conditionTranscription profiling of small heterodimer partner deficiency (SHP) knockout mice heart
Adjusted p-valueLog2-fold change
1.8838 × 10-2-1.5
Mlana'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
1.3638 × 10-51.4
Mlana'TMEV infected' at '196 day' vs 'mock control' at '196 day'disease, timeTranscription profiling of mouse spinal cord from mock-infected and Theilers murine encephalomyelitis (TME)-virus infected animals - time series
Adjusted p-valueLog2-fold change
5.6682 × 10-4-1.4
Mlana'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
7.0672 × 10-4-1.4
Mlana'MEF; transduced with NeuroD2 lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
4.7565 × 10-21.4
Mlana'60 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance
Adjusted p-valueLog2-fold change
2.0363 × 10-51.3
Mlana'osteoblast culture 9 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
5.1746 × 10-5-1.3
Mlana'Lkb1 -/- Pten-/-' vs 'wild type'genotypeLoss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells
Adjusted p-valueLog2-fold change
2.2723 × 10-4-1.3
Mlana'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
4.5278 × 10-4-1.3
Mlana'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
4.6512 × 10-41.3
Mlana'p60 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA'RNA interferenceRNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells
Adjusted p-valueLog2-fold change
9.8151 × 10-41.3
Mlana'TMEV infected' at '98 day' vs 'mock control' at '98 day'disease, timeTranscription profiling of mouse spinal cord from mock-infected and Theilers murine encephalomyelitis (TME)-virus infected animals - time series
Adjusted p-valueLog2-fold change
2.0256 × 10-3-1.3
Mlana'dox-induced over-expression of oncogenes for 5 days then off 7 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
3.501 × 10-31.3
Mlana'24 hour' vs '0 hour' in 'WT1-KTS'genotype, timeEWS-WT1 Oncogene Activates a Neuronal Reprogramming Factor ASCL1 and Mediates Partial Neural Differentiation
Adjusted p-valueLog2-fold change
7.7851 × 10-3-1.3
Mlana'Setd5 homozygous (null) knockout' vs 'Setd5 heterozygous knockout'genotypeTranscriptional profiling of Setd5 heterozygous and knockout mouse embryonic stem cells
Adjusted p-valueLog2-fold change
3.3447 × 10-21.3
Mlana'Drosha -/-' vs 'wild type genotype'genotypeRNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs
Adjusted p-valueLog2-fold change
1.5148 × 10-31.2
Mlana'Alkbh1-/-' vs 'wild type'genotypeTranscription profiling by array of wild type and Alkbh1 knock out mouse embyronic stem cells
Adjusted p-valueLog2-fold change
4.0769 × 10-2-1.2
Mlana'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
5.6098 × 10-41.1
Mlana'p150 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA'RNA interferenceRNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells
Adjusted p-valueLog2-fold change
6.1549 × 10-3-1.1
Mlana'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
7.3763 × 10-3-1.1
Mlana'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic'compound, genotypeNovel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice.
Adjusted p-valueLog2-fold change
2.4013 × 10-2-1.1
Mlana'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
6.6871 × 10-4-1
Mlana'SARS coronavirus MA15' vs 'none' at '4 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
2.7726 × 10-3-1
Mlana'MEF; transduced with MyoD lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
3.7209 × 10-3-1
Mlana'PAI1 knockout; SARS MA15; 4 day' vs 'PAI1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
9.0057 × 10-3-1
Mlana'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.1306 × 10-2-1
Mlana'Wls fl/fl ; Lecre +/-' vs 'wild type'genotypeWnt ligands from the embryonic surface ectoderm regulate bimetallic strip optic cup morphogenesis in the mouse
Adjusted p-valueLog2-fold change
1.7171 × 10-2-1
Mlana'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.