ensmusg00000023947 (Nfkbie)

mus musculus

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon

Filter your results

Mus musculus
Organism part
Showing 29 experiments:
image/svg+xml aorta circulatory system blood vessel brown adipose tissue white adipose tissue skin stomach duodenum pancreas spleen adrenal gland kidney colon small intestine caecum jejunum ileum esophagus gall bladder parotid gland submandibular gland lymph node parathyroid gland tongue Peyer’s patch prostate gland vas deferens epididymis testis seminal vesicle penis urinary bladder thymus femur bone marrow cartilage quadriceps femoris spinal cord lung diaphragm peripheral nervous system trachea hindlimb trigeminal nerve eye sciatic nerve intestinal mucosa liver heart brain skeletal muscle
P
Proteomics
T
Transcriptomics
High
Medium
Low
Below cutoff
No data available

Filter your results

Kingdom
Species
Experiment type
Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
00
Log2-fold change
5.9
Nfkbie'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.7383 × 10-1935.6
Nfkbie'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.5294 × 10-425
Nfkbie'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
3.029 × 10-1474.9
Nfkbie'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
6.9893 × 10-1414.8
Nfkbie'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
00
Log2-fold change
4.7
Nfkbie'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
3.8509 × 10-364.6
Nfkbie'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.0002 × 10-1824.5
Nfkbie'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
9.9134 × 10-124.3
Nfkbie'West Nile virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
1.3306 × 10-664.2
Nfkbie'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
00
Log2-fold change
4
Nfkbie'Debaryomyces hansenii' at '2 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
5.2957 × 10-943.9
Nfkbie'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.3846 × 10-263.9
Nfkbie'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
6.2748 × 10-53.9
Nfkbie'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.6663 × 10-1903.7
Nfkbie'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout'compound, genotypeQuantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes
Adjusted p-valueLog2-fold change
5.1606 × 10-1223.7
Nfkbie'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
9.116 × 10-73.5
Nfkbie'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
4.1113 × 10-83.4
Nfkbie'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.9529 × 10-43.4
Nfkbie'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.1722 × 10-653.3
Nfkbie'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
5.8028 × 10-63.3
Nfkbie'Mycobacterium tuberculosis; DBA/2J congenic; 30 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
6.2768 × 10-83.2
Nfkbie'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
1.5297 × 10-73.2
Nfkbie'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 70 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.2975 × 10-73.2
Nfkbie'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
2.2719 × 10-63.2
Nfkbie'Chikungunya virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
9.3611 × 10-383.1
Nfkbie'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
3.1515 × 10-113.1
Nfkbie'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
1.5251 × 10-73.1
Nfkbie'polarized with E coli lipopolysacharide and INF-gamma' vs 'untreated'compound, treatmentExpression data from polarized macrophages: effect of p53
Adjusted p-valueLog2-fold change
6.7279 × 10-483
Nfkbie'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.0431 × 10-83
Nfkbie'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
8.6233 × 10-82.9
Nfkbie'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.2118 × 10-72.9
Nfkbie'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 30 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
4.9304 × 10-72.9
Nfkbie'West Nile virus; late stage encephalitis' vs 'early stage encephalitis'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
1.6445 × 10-2452.8
Nfkbie'Debaryomyces hansenii' at '6 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
3.3162 × 10-252.8
Nfkbie'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.3006 × 10-142.8
Nfkbie'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
1.5789 × 10-4-2.8
Nfkbie'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
1.5164 × 10-3-2.8
Nfkbie'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
8.5721 × 10-382.7
Nfkbie'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.3928 × 10-62.7
Nfkbie'Mycobacterium tuberculosis; D2.B6-Chr7 congenic; 30 day' vs 'control; D2.B6-Chr7 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.8379 × 10-2462.6
Nfkbie'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.2993 × 10-282.6
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
3.2995 × 10-152.6
Nfkbie'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
3.2635 × 10-92.6
Nfkbie'TNFα' vs 'none' in 'wild type'genotype, treatmentIdentification of TNFα-induced genes that are IRAK1BP1 dependent
Adjusted p-valueLog2-fold change
5.4897 × 10-72.6
Nfkbie'lipopolysaccharide; 100 nanogram per milliliter and interferon gamma 20 nanogram per milliliter' vs 'none'stimulusTranscriptional profiling in macrophages in stimulated and unstimulated conditions.
Adjusted p-valueLog2-fold change
9.0697 × 10-7-2.6
Nfkbie'interferon gamma' vs 'none'compoundType I and II Interferon-Stimulated Genes in Murine Primary Bone Marrow Macrophages
Adjusted p-valueLog2-fold change
1.4462 × 10-42.6
Nfkbie'Chikungunya virus; late stage encephalitis' vs 'early stage encephalitis'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
4.7388 × 10-4-2.6
Nfkbie'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
2.9568 × 10-372.5
Nfkbie'interferon gamma' vs 'dexamethasone; 100 nanomolar'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
1.5485 × 10-242.5
Nfkbie'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
2.6309 × 10-132.5
Nfkbie'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
5.4352 × 10-72.5
Nfkbie'ko cyld-/-' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Cyld inactivation
Adjusted p-valueLog2-fold change
4.7018 × 10-62.5
Nfkbie'70 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
2.8353 × 10-52.5
Nfkbie'cycloheximide and 100 unit per milliliter interferon alpha' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
3.8782 × 10-42.5
Nfkbie'SARS coronavirus MA15' vs 'none' at '1 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
7.3383 × 10-32.5
Nfkbie'Staphylococcus aureus cutaneous infection' vs 'none' in 'wild type'disease, genotypeNeutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice
Adjusted p-valueLog2-fold change
3.0074 × 10-22.5
Nfkbie'neural stem cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
1.9271 × 10-202.4
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.0178 × 10-182.4
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.9774 × 10-132.4
Nfkbie'Escherichia coli O18:K1:H7; 2 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.2114 × 10-102.4
Nfkbie'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.2303 × 10-72.4
Nfkbie'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
7.4086 × 10-52.4
Nfkbie'3 day' vs '1 day' in 'influenza A infected DBA/2J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
2.2732 × 10-182.3
Nfkbie'12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
1.0005 × 10-7-2.3
Nfkbie'interferon alpha' vs 'none'compoundType I and II Interferon-Stimulated Genes in Murine Primary Bone Marrow Macrophages
Adjusted p-valueLog2-fold change
3.1073 × 10-72.3
Nfkbie'TNF-alpha' vs 'control' in 'myotube; 4 hours differentiation'cell type, developmental stage, stimulusGene expression profiling of skeletal myoblast differentiation and exposure to TNF-alpha or IGF1
Adjusted p-valueLog2-fold change
1.2015 × 10-5-2.3
Nfkbie'Rb;E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.7971 × 10-5-2.3
Nfkbie'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
2.8931 × 10-42.3
Nfkbie'SARS coronavirus MA15' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
5.2815 × 10-42.3
Nfkbie'cycloheximide' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
3.2328 × 10-32.3
Nfkbie'tumor necrosis factor-alpha' at '4 hour' vs 'control' at '4 hour'stimulus, timeGenome-wide comparison between IL-17 and combined TNF-alpha/ IL-17 induced genes in primary murine hepatocytes
Adjusted p-valueLog2-fold change
2.2513 × 10-542.2
Nfkbie'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
9.1412 × 10-23-2.2
Nfkbie'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
9.9296 × 10-212.2
Nfkbie'SARS coronavirus MA15; 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.1831 × 10-112.2
Nfkbie'Mycobacterium tuberculosis H37Rv' vs 'none' in 'wild type'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
6.1469 × 10-92.2
Nfkbie'TNFα' vs 'none' in 'IRAK1BP1 KO'genotype, treatmentIdentification of TNFα-induced genes that are IRAK1BP1 dependent
Adjusted p-valueLog2-fold change
1.3923 × 10-72.2
Nfkbie'Escherichia coli O18:K1:H7; 2 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.5793 × 10-72.2
Nfkbie'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.3449 × 10-72.2
Nfkbie'wild type; treated with angiotensin II and a combination of hydralazine and hydrochlorothiazide' vs 'wild type; vehicle'genotype, treatmentEffect of Hypertension of Dendritic Cell Gene Expression
Adjusted p-valueLog2-fold change
6.2502 × 10-72.2
Nfkbie'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.7963 × 10-42.2
Nfkbie'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
5.1101 × 10-42.2
Nfkbie'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
6.0827 × 10-32.2
Nfkbie'Staphylococcus aureus cutaneous infection' vs 'none' in 'IL-1R knockout'disease, genotypeNeutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice
Adjusted p-valueLog2-fold change
3.6056 × 10-1172.1
Nfkbie'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
1.1358 × 10-202.1
Nfkbie'Mycobacterium tuberculosis H37Rv' vs 'none'infectThe global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice
Adjusted p-valueLog2-fold change
8.7344 × 10-92.1
Nfkbie'3D culture' vs '2D culture'growth conditionmRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture
Adjusted p-valueLog2-fold change
6.578 × 10-82.1
Nfkbie'Trichuris muris' vs 'control' in 'non wormy; caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
2.6192 × 10-52.1
Nfkbie'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.0797 × 10-42.1
Nfkbie'Metarhizium anisopliae crude antigen' vs 'vehicle' at '3 hour'compound, timeTranscription profiling of mouse lungs following exposure to agents of high or low allergenicity
Adjusted p-valueLog2-fold change
2.833 × 10-42.1
Nfkbie'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
8.8042 × 10-42.1
Nfkbie'unilateral ureteral obstruction' vs 'sham' in 'wild type'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
9.0775 × 10-32.1
Nfkbie'H-Ras expression' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
9.8503 × 10-32.1
Nfkbie'inhibitor of kappaB kinase beta constitutively active' vs 'wild type'phenotypeTranscription profiling by array of primary murine cardiomyocytes with and without expression of constitutively active IKK2
Adjusted p-valueLog2-fold change
2.1482 × 10-982
Nfkbie'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
1.4526 × 10-132
Nfkbie'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
9.4363 × 10-82
Nfkbie'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal'diseaseTranscription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma
Adjusted p-valueLog2-fold change
1.2967 × 10-72
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.9905 × 10-72
Nfkbie'CHOP-/-' vs 'wild type' in 'DMSO'compound, genotypeMicroarray to find CHOP dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
9.6907 × 10-62
Nfkbie'renin-expression' vs 'control'phenotypeExpression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein.
Adjusted p-valueLog2-fold change
1.0408 × 10-52
Nfkbie'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
4.352 × 10-52
Nfkbie'10 microgram; ovalbumin' vs 'none' in 'wild type'compound, genotypeTranscription profiling by array of lungs from mice mutant for RAG after challenge with ovalbumin
Adjusted p-valueLog2-fold change
1.0823 × 10-32
Nfkbie'SARS coronavirus MA15 dORF6' vs 'none' at '1 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
7.06 × 10-3-2
Nfkbie'Macrophage of F4/80+, CD11b+, CD11c-+; obese leptin-deficient' vs 'Macrophage of F4/80+, CD11b+, CD11c-+; control'cell type, genotypeExpression data from mouse adipose tissue macrophage
Adjusted p-valueLog2-fold change
7.8692 × 10-32
Nfkbie'ulcer' vs 'distant normal tissue' in 'Bmp4 overexpression'genotype, sampling site, timeIntestinal ulcers from biopsy-wounded wild-type and Bmp4-overexpressing mice
Adjusted p-valueLog2-fold change
1.0775 × 10-22
Nfkbie'alopecia areata' vs 'normal'diseaseMouse Spontaneous C3H/HeJ AA Skin
Adjusted p-valueLog2-fold change
2.0689 × 10-22
Nfkbie'Taf10-/-' vs 'wild type'genotypeTranscription profiling by array of liver from Taf10 knock out mice
Adjusted p-valueLog2-fold change
6.0958 × 10-241.9
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.6384 × 10-131.9
Nfkbie'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.8927 × 10-101.9
Nfkbie'wild type; SARS MA15; 2 day' vs 'wild type; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
2.1455 × 10-71.9
Nfkbie'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
4.2593 × 10-71.9
Nfkbie'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.9221 × 10-61.9
Nfkbie'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.3919 × 10-51.9
Nfkbie'4 day' vs '1 day' in 'influenza A infected DBA/2J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
2.3836 × 10-5-1.9
Nfkbie'E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
3.1394 × 10-51.9
Nfkbie'smoke; 3000 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
6.9669 × 10-51.9
Nfkbie'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
9.2927 × 10-51.9
Nfkbie'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.6552 × 10-41.9
Nfkbie'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.1709 × 10-621.8
Nfkbie'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
5.6168 × 10-601.8
Nfkbie'Tumor Necrosis Factor' vs 'none'stimulusTranscription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor
Adjusted p-valueLog2-fold change
8.2028 × 10-271.8
Nfkbie'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
6.9613 × 10-191.8
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
7.9855 × 10-111.8
Nfkbie'Helicobacter hepaticus' vs 'none' in 'wild type phenotype'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
2.4346 × 10-71.8
Nfkbie'MG132; 1 micromolar' vs 'DMSO' in 'wild type'compound, genotypeMicroarray to find CHOP dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
2.9287 × 10-71.8
Nfkbie'Er81 overexpression' vs 'wild type'phenotypeExpression analysis of Pea3, Erm and Er81 overexpression in mHypoA-2/12 cell line
Adjusted p-valueLog2-fold change
1.1357 × 10-61.8
Nfkbie'10 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
1.4853 × 10-61.8
Nfkbie'inhibitor of kappaB kinase beta constitutively active-transgenic' vs 'wild type or single transgenic'genotypeTranscription profiling by array of embryonic mouse heart ventricles with and without cardiomycocyte-specific expression of constitutively active IKK2
Adjusted p-valueLog2-fold change
1.66 × 10-61.8
Nfkbie'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.7026 × 10-61.8
Nfkbie'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.5649 × 10-51.8
Nfkbie'SARS coronavirus MA15 dORF6' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
6.1168 × 10-51.8
Nfkbie'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
2.2946 × 10-41.8
Nfkbie'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
2.9256 × 10-4-1.8
Nfkbie'dexamethasome' vs 'methyl beta-clodextrin' in 'Nr1d1 homozygous knockout; 1 milligram per kilogram; ZT6'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
5.2001 × 10-41.8
Nfkbie'2 day' vs '1 day' in 'influenza A infected DBA/2J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
3.7491 × 10-31.8
Nfkbie'130 week' vs '13 week' in 'kidney'age, organism partTranscription profiling by array of liver, lung, spleen and kidney from young and old mice.
Adjusted p-valueLog2-fold change
9.4519 × 10-31.8
Nfkbie'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
2.3454 × 10-391.7
Nfkbie'lipopolysaccharide' vs 'none' in 'bone marrow; wild type'cell type, compound, genotypeTranscription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice
Adjusted p-valueLog2-fold change
6.4578 × 10-251.7
Nfkbie'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
8.4464 × 10-161.7
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.4079 × 10-81.7
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.2928 × 10-81.7
Nfkbie'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
2.7296 × 10-71.7
Nfkbie'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
1.0327 × 10-6-1.7
Nfkbie'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'classical monocyte'cell type, genotypeRNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice
Adjusted p-valueLog2-fold change
2.3814 × 10-6-1.7
Nfkbie'acute myeloid leukemia' vs 'myeloproliferative disorder'diseaseTranscription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm
Adjusted p-valueLog2-fold change
3.5738 × 10-61.7
Nfkbie'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.4665 × 10-61.7
Nfkbie'4 day' vs '1 day' in 'influenza A infected C57BL/6J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
3.8783 × 10-51.7
Nfkbie'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.079 × 10-41.7
Nfkbie'6 week' vs '0 week'timeTranscription profiling by array of mouse colon tissues with T cell transfer-induced colitis at week 0, 2, 4 and 6 post-transfer
Adjusted p-valueLog2-fold change
1.1954 × 10-41.7
Nfkbie'Erm overexpression' vs 'wild type'phenotypeExpression analysis of Pea3, Erm and Er81 overexpression in mHypoA-2/12 cell line
Adjusted p-valueLog2-fold change
1.6803 × 10-41.7
Nfkbie'SARS coronavirus MA15' vs 'none' at '2 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
2.0284 × 10-41.7
Nfkbie'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 2 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
3.6875 × 10-4-1.7
Nfkbie'Dicer knock out' vs 'wild type'genotypeTranscription profiling by array of mouse Dicer-deficient ooctyes
Adjusted p-valueLog2-fold change
4.2815 × 10-41.7
Nfkbie'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'BALB/cByJ'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
6.7021 × 10-41.7
Nfkbie'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
8.512 × 10-41.7
Nfkbie'cycloheximide and 100 unit per milliliter interferon gamma' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
1.3416 × 10-3-1.7
Nfkbie'dexamethasome' vs 'methyl beta-clodextrin' in 'Nr1d1 homozygous knockout; 1 milligram per kilogram; ZT18'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
5.3431 × 10-3-1.7
Nfkbie'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
6.4133 × 10-31.7
Nfkbie'interleukin-1 beta (Mus musculus)' at '1 hour' vs 'control' at '1 hour'stimulus, timeGenome-wide comparison between IL-17 and combined TNF-alpha/ IL-17 induced genes in primary murine hepatocytes
Adjusted p-valueLog2-fold change
7.8483 × 10-31.7
Nfkbie'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
1.6831 × 10-21.7
Nfkbie'activated neutrophils' vs 'control neutrophils'sampling time point, treatmentExpression data from control, aged and activated neutrophils in mouse blood
Adjusted p-valueLog2-fold change
9.5238 × 10-781.6
Nfkbie'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
4.4542 × 10-641.6
Nfkbie'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
2.5401 × 10-231.6
Nfkbie'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
6.5133 × 10-141.6
Nfkbie'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.0689 × 10-101.6
Nfkbie'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
9.2551 × 10-9-1.6
Nfkbie'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
1.4911 × 10-71.6
Nfkbie'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.8644 × 10-71.6
Nfkbie'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.1934 × 10-61.6
Nfkbie'Staphylococcus aureus Sanger476; 6 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
7.7798 × 10-61.6
Nfkbie'Influenza A virus' vs 'mock' in 'interleukin-22'infect, stimulusTranscription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza
Adjusted p-valueLog2-fold change
3.0233 × 10-51.6
Nfkbie'3 day' vs '1 day' in 'influenza A infected C57BL/6J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
3.3714 × 10-51.6
Nfkbie'RBPjk null' vs 'wild type'genotypeQuantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS
Adjusted p-valueLog2-fold change
4.1572 × 10-51.6
Nfkbie'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-'compound, genotypeInhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2)
Adjusted p-valueLog2-fold change
5.0955 × 10-5-1.6
Nfkbie'MYC inhibitor (10058F4); polarized with interleukin 4 and interleukin 13.' vs 'untreated'compound, treatmentExpression data from polarized macrophages: effect of p53
Adjusted p-valueLog2-fold change
5.1135 × 10-51.6
Nfkbie'7 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
8.1309 × 10-51.6
Nfkbie'dinitrofluorobenzene' vs 'control' in 'wild type'compound, genotypeTranscription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity
Adjusted p-valueLog2-fold change
1.8467 × 10-41.6
Nfkbie'CpG ODN' vs 'PBS' at '4 hour'compound, timeTranscription profiling by array of mouse vaginal samples following adjuvant treatment
Adjusted p-valueLog2-fold change
3.4016 × 10-41.6
Nfkbie'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 2 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.8334 × 10-31.6
Nfkbie'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
8.4655 × 10-31.6
Nfkbie'130 week' vs '13 week' in 'liver'age, organism partTranscription profiling by array of liver, lung, spleen and kidney from young and old mice.
Adjusted p-valueLog2-fold change
9.1928 × 10-31.6
Nfkbie'H-Ras expression; c-Myc activation' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
1.3323 × 10-571.5
Nfkbie'CpG; 6 hour' vs 'none; 0 hour' in 'none'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
2.4588 × 10-541.5
Nfkbie'Tumor Necrosis Factor' vs 'phosphate buffered saline'stimulusTranscription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor
Adjusted p-valueLog2-fold change
1.1182 × 10-20-1.5
Nfkbie'Rel -/-; Nfkb1-/-; CD4Cre Rela fx/fx' vs 'wild type genotype'genotypeRNA-seq of CD8 single positive thymocytes from WT and Rela fx/fx CD4Cre Nfkb1KO RelKO mice.
Adjusted p-valueLog2-fold change
5.2395 × 10-201.5
Nfkbie"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "PWK/PhJ"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
1.17 × 10-131.5
Nfkbie'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
2.2528 × 10-81.5
Nfkbie'wild type genotype; SARS MA15; 7 day' vs 'wild type genotype; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
4.2627 × 10-61.5
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.8888 × 10-5-1.5
Nfkbie'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
2.0458 × 10-51.5
Nfkbie'SARS coronavirus MA15 nsp16 -/-' vs 'none' at '2 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
2.2814 × 10-51.5
Nfkbie'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
5.4769 × 10-51.5
Nfkbie'trichostatin A and LIF' at '6 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
6.0556 × 10-51.5
Nfkbie'SARS coronavirus MA15' vs 'none' in 'Tnfrsf1a/1b -/-' at '4 day'genotype, infect, timeSM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Adjusted p-valueLog2-fold change
9.7743 × 10-51.5
Nfkbie'osteoblast culture 9 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
1.0122 × 10-41.5
Nfkbie'dinitrofluorobenzene' vs 'control' in 'Cnr1 -/- /Cnr2 -/-'compound, genotypeTranscription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity
Adjusted p-valueLog2-fold change
1.3744 × 10-41.5
Nfkbie'smoke; 3000 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
2.8641 × 10-41.5
Nfkbie'smoke; 3000 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
4.4224 × 10-41.5
Nfkbie'smoke; 1500 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
6.9604 × 10-41.5
Nfkbie'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
1.3041 × 10-31.5
Nfkbie'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
3.4547 × 10-3-1.5
Nfkbie'dexamethasome' vs 'methyl beta-clodextrin' in 'wild type genotype; 1 milligram per kilogram; ZT18'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
5.9319 × 10-31.5
Nfkbie'10 nanogram per milliliter; TGF-beta1' vs 'none' in 'common dendritic progenitor' at '24 hour'cell type, compound, timeDynamic Gene Expression Response to TGF-b Stimulation in Multipotent Progenitors and Common Dendritic Cell Progenitors
Adjusted p-valueLog2-fold change
9.6509 × 10-3-1.5
Nfkbie'RAW264.7 macrophage cell line; control' vs 'bone marrow macrophage; control'cell type, growth conditionTranscription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line
Adjusted p-valueLog2-fold change
1.1434 × 10-2-1.5
Nfkbie'AhCre Apc Floxed Cited1 knockout' vs 'control'genotypeCited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis
Adjusted p-valueLog2-fold change
1.7241 × 10-21.5
Nfkbie'Ezh2 knockout' vs 'control'genotypeExpression profiling of secondary wild type (WT) and Ezh2-null murine MLL-AF9 AML
Adjusted p-valueLog2-fold change
1.9158 × 10-2-1.5
Nfkbie'6 days after third immunization' vs '3 months after second immunization'sampling time pointTranscription profiling of newly generated and mature mouse splenic plasma cells after immunization with sheep red blood cells
Adjusted p-valueLog2-fold change
2.2489 × 10-21.5
Nfkbie'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
4.032 × 10-21.5
Nfkbie'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
4.8153 × 10-21.5
Nfkbie'14M1.4; Leishmania donovani infected' at '12 hour' vs '14M1.4; normal' at '12 hour'cell line, infect, timeTranscription profiling of 3 mouse cell lines infected with Leishmania
Adjusted p-valueLog2-fold change
2.5751 × 10-121.4
Nfkbie'corpus striatum' at 'rheumatoid arthritis model expressing hsTNFɑ' vs 'wild type'disease, organism part, phenotypeRegional CNS immune fingerprint in chronic peripheral inflammation
Adjusted p-valueLog2-fold change
5.581 × 10-81.4
Nfkbie'RBM20 antisense oligonucleotide' vs 'none' in 'wild type genotype'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
1.115 × 10-61.4
Nfkbie'Porphyromonas gingivalis; hyperlipidemia' vs 'normal'infect, phenotypehyperlipidemia impaired innate response
Adjusted p-valueLog2-fold change
1.3759 × 10-61.4
Nfkbie'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
1.6605 × 10-61.4
Nfkbie'Porphyromonas gingivalis; normal' vs 'normal'infect, phenotypehyperlipidemia impaired innate response
Adjusted p-valueLog2-fold change
1.9734 × 10-51.4
Nfkbie'Staphylococcus aureus Sanger476; 4 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
3.368 × 10-51.4
Nfkbie'SARS coronavirus MA15' vs 'none' at '2 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
7.2719 × 10-51.4
Nfkbie'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 15 days post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
8.1317 × 10-5-1.4
Nfkbie'myeloid progenitor cell; FoxO1/3/4 triple knockout' vs 'myeloid progenitor cell; wild type genotype'cell type, genotypeTranscription profiling of bone marrow hematopoietic stem cells and myeloid progenitors from mice with conditional deletion of Forkhead O (FoxO) family of transcription factors
Adjusted p-valueLog2-fold change
9.1642 × 10-51.4
Nfkbie'Staphylococcus aureus Sanger476; 4 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.1822 × 10-41.4
Nfkbie'lung carcinoma' vs 'normal' in 'Epcam+CD11b-CD11c- epithelial cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
1.6217 × 10-41.4
Nfkbie'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day'genotype, infect, timeSM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Adjusted p-valueLog2-fold change
3.2836 × 10-41.4
Nfkbie'5 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
3.6078 × 10-4-1.4
Nfkbie'erythroblast' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
4.2376 × 10-41.4
Nfkbie'cecal ligation and puncture surgery' vs 'sham surgery' in 'wild type'clinical treatment, genotypeGene expression profile in lung tissue 8 h after inducing polymicrobial sepsis in preprotachykinin-A (PPTA) knockout mice and wild type
Adjusted p-valueLog2-fold change
8.7769 × 10-4-1.4
Nfkbie'Nix knock out' vs 'wild type'genotypeTranscription profiling by array of spleens from mice with Nix knocked out.
Adjusted p-valueLog2-fold change
2.2865 × 10-31.4
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'NZO/HILtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
5.3068 × 10-31.4
Nfkbie'HDM allergen; IL-13 knockout' vs 'PBS control; IL-13 knockout' on 'Affymetrix MOE430B Array'compound, genotypeTranscription profiling of wild type and IL13 knock out mice treated with allergen vs. control to investigate the IL13 role in allergic asthma
Adjusted p-valueLog2-fold change
1.1048 × 10-21.4
Nfkbie'interleukin-1 beta (Mus musculus)' at '4 hour' vs 'control' at '4 hour'stimulus, timeGenome-wide comparison between IL-17 and combined TNF-alpha/ IL-17 induced genes in primary murine hepatocytes
Adjusted p-valueLog2-fold change
2.3325 × 10-21.4
Nfkbie'20 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance
Adjusted p-valueLog2-fold change
2.3413 × 10-21.4
Nfkbie'Gata6 knockout' vs 'wild type'phenotypeGlobal gene expression in the adult Gata6 null mouse pancreas
Adjusted p-valueLog2-fold change
2.3438 × 10-21.4
Nfkbie'cecal ligation and puncture surgery' vs 'sham surgery' in 'PPTA knockout'clinical treatment, genotypeGene expression profile in lung tissue 8 h after inducing polymicrobial sepsis in preprotachykinin-A (PPTA) knockout mice and wild type
Adjusted p-valueLog2-fold change
2.9411 × 10-21.4
Nfkbie'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
2.9543 × 10-21.4
Nfkbie'5 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance
Adjusted p-valueLog2-fold change
1.8373 × 10-311.3
Nfkbie'KRas siRNA' vs 'non-targeting siRNA'RNA interferenceRNA-SEQ analysis of KMC murine pancreatic ductal adenocarcinoma (PDAC) cell line upon siRNA depletion of MYC, KRas or Miz1 (aka Zbtb17)
Adjusted p-valueLog2-fold change
1.5473 × 10-271.3
Nfkbie'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
8.0771 × 10-181.3
Nfkbie'interleukin-36 gamma; 30 microgram per liter' vs 'none; 'compoundTranscriptional profiling of colonic mouse fibroblasts stimulated with interleukin-36 gamma
Adjusted p-valueLog2-fold change
2.2696 × 10-141.3
Nfkbie'high GLUT1 expression' vs 'low GLUT1 expression' in 'wild type genotype'genotype, phenotypeRNA-seq analysis of normoxic and hypoxic tumor-associated macrophages from wild type or REDD1 knockout mice
Adjusted p-valueLog2-fold change
5.5861 × 10-131.3
Nfkbie'interferon gamma' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
2.2995 × 10-81.3
Nfkbie'ATF5 knockdown' vs 'wild type' in 'DMSO'compound, genotypeMicroarray to find ATF5 dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
7.9943 × 10-71.3
Nfkbie'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
8.0217 × 10-71.3
Nfkbie'dorsal+ventral thalamus' at 'rheumatoid arthritis model expressing hsTNFɑ' vs 'wild type'disease, organism part, phenotypeRegional CNS immune fingerprint in chronic peripheral inflammation
Adjusted p-valueLog2-fold change
1.0716 × 10-61.3
Nfkbie'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; STI571 treated' vs 'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; untreated'cell type, treatmentGene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice
Adjusted p-valueLog2-fold change
2.7704 × 10-61.3
Nfkbie"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "A/J"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
2.9288 × 10-61.3
Nfkbie'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
4.9776 × 10-61.3
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.0294 × 10-51.3
Nfkbie'Pkhd1Cre; Pkd2 F/F; miR-21null' vs 'wild type'genotypeNext Generation Sequencing of PKD2 mutant mice kidneys
Adjusted p-valueLog2-fold change
1.6996 × 10-51.3
Nfkbie'SARS coronavirus MA15; 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.4587 × 10-51.3
Nfkbie'Metarhizium anisopliae crude antigen' vs 'vehicle' at '12 hour'compound, timeTranscription profiling of mouse lungs following exposure to agents of high or low allergenicity
Adjusted p-valueLog2-fold change
1.017 × 10-41.3
Nfkbie'ATF3 -/-' vs 'wild type' in '10 nanogram per milliliter; lipopolysaccharide' at '1 hour'compound, genotype, timeTranscription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide
Adjusted p-valueLog2-fold change
2.872 × 10-41.3
Nfkbie'confluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.9649 × 10-41.3
Nfkbie'5-azacytidine 10 micromolar' vs 'none'compoundTranscription profiling by array of mouse C2C12 cells treated with 5-azacytidine
Adjusted p-valueLog2-fold change
3.889 × 10-41.3
Nfkbie'TIMP1 knockout; SARS MA15; 7 day' vs 'TIMP1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
6.6696 × 10-41.3
Nfkbie'21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
8.3953 × 10-41.3
Nfkbie'smoke; 1500 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.035 × 10-31.3
Nfkbie'West Nile virus; early stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
1.4971 × 10-31.3
Nfkbie'9 day' vs '0 day'timeTranscription profiling by array of mineralising murine vascular smooth muscle cell cultures over a nine day culture period to identify new regulators of vascular mineralization
Adjusted p-valueLog2-fold change
3.323 × 10-31.3
Nfkbie'SARS coronavirus MA15; 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
6.0981 × 10-31.3
Nfkbie'acute DSS-induced colitis; 1x DSS, no recovery' vs 'none; none'clinical treatment, diseaseTranscription profiling by array of colon tissues isolated from mice with acute and chronic dextran sodium sulphate (DSS)-induced colitis
Adjusted p-valueLog2-fold change
2.4242 × 10-21.3
Nfkbie'SARS coronavirus MA15 E protein mutant Δ3' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
3.4097 × 10-2-1.3
Nfkbie'TRIM28(flox/flox):Mx1Cre' vs 'TRIM28(flox/flox)' in 'CD71(hi)TER119-'genotype, phenotypeTranscription profiling by high throughput sequencing of bone marrow immature erythroid cells from Trim28flox/flox:TgMx1Cre congenic mice
Adjusted p-valueLog2-fold change
3.4127 × 10-2-1.3
Nfkbie'Cbir-flagellin' vs 'none' in 'B6-interleukin 10-/-'stimulus, strainTranscription profiling of bone marrow-derived macrophages from colitis-resistant and colitis-susceptible interleukin-10-deficient strains stimulated with Cbir-flagellin
Adjusted p-valueLog2-fold change
4.4196 × 10-21.3
Nfkbie'SARS coronavirus MA15; 10^2 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
1.4158 × 10-61-1.2
Nfkbie'Ts1Rhr; KRASG12D' vs 'wild type genotype'genotypeRNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D
Adjusted p-valueLog2-fold change
2.742 × 10-301.2
Nfkbie'Debaryomyces hansenii' at '24 hour' vs 'none' at '0 hour'stimulus, timeRNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls
Adjusted p-valueLog2-fold change
7.9523 × 10-161.2
Nfkbie'S-(1,2-dichlorovinyl)-L-cysteine; 15 milligram per kilogram; renal injury; 1 week' vs 'none; normal'compound, disease, timeExpression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC
Adjusted p-valueLog2-fold change
4.4273 × 10-131.2
Nfkbie'8.5 millimolar; methoxyacetic acid' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid
Adjusted p-valueLog2-fold change
8.5901 × 10-121.2
Nfkbie'SARS coronavirus MA15; 4 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.3318 × 10-11-1.2
Nfkbie'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
6.2696 × 10-81.2
Nfkbie'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.7007 × 10-71.2
Nfkbie'wild type; SARS MA15; 7 day' vs 'wild type; mock'genotype, infect, timeInfection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15
Adjusted p-valueLog2-fold change
9.9456 × 10-71.2
Nfkbie'tamoxifen; autosomal dominant polycystic kidney disease' vs 'none; normal'compound, disease, timeExpression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC
Adjusted p-valueLog2-fold change
1.7009 × 10-61.2
Nfkbie'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.2464 × 10-61.2
Nfkbie'SARS coronavirus MA15; 4 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.5341 × 10-51.2
Nfkbie'Influenza A virus' vs 'mock' in 'IgG1'infect, stimulusTranscription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza
Adjusted p-valueLog2-fold change
4.7744 × 10-51.2
Nfkbie'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '7 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
7.0627 × 10-5-1.2
Nfkbie'stromal cell; E2' vs 'stromal cell; vehicle'cell type, treatmentAffymetrix gene chip analysis for the whole mouse genome transcripts of epithelial and stromal cells from mouse uterine primary co-culture treated with either vehicle or E2
Adjusted p-valueLog2-fold change
7.5701 × 10-51.2
Nfkbie'sham-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle'clinical treatmentTranscription profiling by array of mice with epileptic tolerance
Adjusted p-valueLog2-fold change
1.1462 × 10-41.2
Nfkbie'smoke; 1500 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 1 day post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.3438 × 10-41.2
Nfkbie'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.0241 × 10-41.2
Nfkbie'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
2.8641 × 10-41.2
Nfkbie'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day'genotype, infect, timeSM020 - Infection with SARS MA15 of C57BL/6J mice and KEPI (ppp1r14c) knockouts
Adjusted p-valueLog2-fold change
3.0924 × 10-41.2
Nfkbie'4 week' vs '0 week'timeTranscription profiling by array of mouse colon tissues with T cell transfer-induced colitis at week 0, 2, 4 and 6 post-transfer
Adjusted p-valueLog2-fold change
3.2609 × 10-41.2
Nfkbie'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '4 day'genotype, infect, timeSM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Adjusted p-valueLog2-fold change
3.8074 × 10-41.2
Nfkbie'smoke; 2250 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
4.1304 × 10-41.2
Nfkbie'SARS coronavirus MA15' vs 'none' at '7 day'infect, timeSM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
7.0753 × 10-4-1.2
Nfkbie'5,9-endoperoxy-cholest-7-en-3β,6α-diol' vs 'vehicle (cyclodextrin)'compound, timeArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
Adjusted p-valueLog2-fold change
8.0706 × 10-4-1.2
Nfkbie'dexamethasone (1 μM) and GW7647 (0.5 μM)' vs 'none'compoundRNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS
Adjusted p-valueLog2-fold change
8.4372 × 10-41.2
Nfkbie'trehalose dimycolated (TDM)' at '24 hour' vs 'phosphatidylglycerol (PG) control' at '24 hour'stimulus, timeTranscription profiling by array of mouse bone marrow-derived macrophages stimulated by trehalose dimycolated (TDM) or phosphatidylglycerol (PG) control to study how mycobacterial TDM reprograms macrophage global gene expression
Adjusted p-valueLog2-fold change
9.3465 × 10-41.2
Nfkbie'21 percent oxygen, 37 degree Celsius, no serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
9.6079 × 10-41.2
Nfkbie'PAI1 knockout; SARS MA15; 7 day' vs 'PAI1 knockout; mock'genotype, infect, timeSARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice
Adjusted p-valueLog2-fold change
1.4907 × 10-31.2
Nfkbie'overexpression of SRC-2' vs 'control'phenotypeA pivotal role of SRC-2 in Metastatic and Castration Resistant Prostate Cancer
Adjusted p-valueLog2-fold change
2.247 × 10-31.2
Nfkbie'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NZO/HILtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.2752 × 10-31.2
Nfkbie'Tetrafluororethane; 50000 part per million; air' vs 'none; ; air'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
2.8352 × 10-31.2
Nfkbie'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '4 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
3.0927 × 10-31.2
Nfkbie'lipid nanoparticle complexed with ribonucleic acid expressing respiratory synctial virus F protein' vs 'phosphate buffered saline'stimulusMicroarray analysis of mouse whole genome using self-amplifying messenger (SAM) RNA delivered with different formulations compared to controls
Adjusted p-valueLog2-fold change
3.7601 × 10-31.2
Nfkbie'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure and 15 days post-exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
4.1434 × 10-31.2
Nfkbie'Pten knockout' vs 'wild type' at '15 month'genotype, timeTranscription profiling by array of Pten knockout liver cells of mouse
Adjusted p-valueLog2-fold change
6.8273 × 10-31.2
Nfkbie'expanded on HUVEC and m5GF in the presence of mD1R for 7 days' vs 'control'treatmentExpression data from cultured c-Kit+Sca-1+Lin- (KSL)cells
Adjusted p-valueLog2-fold change
2.1909 × 10-21.2
Nfkbie'tumor necrosis factor-alpha/interleukin-17 (Mus musculus)' at '4 hour' vs 'control' at '4 hour'stimulus, timeGenome-wide comparison between IL-17 and combined TNF-alpha/ IL-17 induced genes in primary murine hepatocytes
Adjusted p-valueLog2-fold change
2.2488 × 10-2-1.2
Nfkbie'19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Adjusted p-valueLog2-fold change
2.4496 × 10-21.2
Nfkbie'SARS coronavirus MA15; 4 day' vs 'mock' in 'CAST/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.0108 × 10-21.2
Nfkbie'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'AKR/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
4.0288 × 10-2-1.2
Nfkbie'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Adjusted p-valueLog2-fold change
4.1528 × 10-21.2
Nfkbie'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
4.2678 × 10-21.2
Nfkbie'status epilepticus' vs 'none' in 'astrocyte; soticlestat; 30 milligram per kilogram'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
4.4133 × 10-2-1.2
Nfkbie'dexamethasome' vs 'methyl beta-clodextrin' in 'wild type genotype; 1 milligram per kilogram; ZT6'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
8.7263 × 10-161.1
Nfkbie'9V/null' vs 'wild type' in 'saline; lung'compound, genotype, organism partGaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase [RNA-Seq]
Adjusted p-valueLog2-fold change
1.1648 × 10-13-1.1
Nfkbie'dexamethasone; 100 nanomolar' vs 'none'compound, stimulusRNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone
Adjusted p-valueLog2-fold change
3.4308 × 10-9-1.1
Nfkbie'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
3.6816 × 10-91.1
Nfkbie'trans-tympanically injected with Hemophilus influenza' vs 'control'treatmentOtitis Media Impact on Middle Ear
Adjusted p-valueLog2-fold change
1.2292 × 10-7-1.1
Nfkbie'M-CSF' at '3 day' vs 'none' at '0 day'compound, timeMicroarray profiling of polyploid macrophage progeny
Adjusted p-valueLog2-fold change
1.9082 × 10-71.1
Nfkbie'anti-CD3/anti-CD28' vs 'none' in 'empty vector'genotype, stimulusTranscription profiling by array of FOXP3 overexpression in resting and activated mouse CD4+ T cells
Adjusted p-valueLog2-fold change
2.8505 × 10-7-1.1
Nfkbie'proliferating progenitor' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
4.3978 × 10-71.1
Nfkbie'10 Gy Gray; x-ray' vs 'none' in 'tumor and stromal cell'cell type, irradiateRNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated
Adjusted p-valueLog2-fold change
9.5272 × 10-71.1
Nfkbie'RBM20 antisense oligonucleotide' vs 'none' in 'Titin-N2B knockout'RNA interference, genotypeHeart RNA-seq of therapeutic RBM20 antisense oligonucleotide (ASO) treatment in a mouse model of heart failure with preserved ejection fraction (HFpEF)
Adjusted p-valueLog2-fold change
3.7781 × 10-61.1
Nfkbie'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.4883 × 10-51.1
Nfkbie'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
3.9297 × 10-51.1
Nfkbie'seizure-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle'clinical treatmentTranscription profiling by array of mice with epileptic tolerance
Adjusted p-valueLog2-fold change
7.8355 × 10-51.1
Nfkbie'2 day' vs '1 day' in 'influenza A infected C57BL/6J'disease, strain, timeTranscription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection
Adjusted p-valueLog2-fold change
1.5045 × 10-4-1.1
Nfkbie'14 days P. chabaudi infected' vs 'uninfected' in 'intact male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
1.5049 × 10-41.1
Nfkbie'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'wild type'compound, genotypeInhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2)
Adjusted p-valueLog2-fold change
4.3222 × 10-41.1
Nfkbie'trichostatin A and LIF' at '12 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
4.9684 × 10-41.1
Nfkbie'Pkhd1Cre; Pkd2 F/F' vs 'wild type'genotypeNext Generation Sequencing of PKD2 mutant mice kidneys
Adjusted p-valueLog2-fold change
5.6292 × 10-41.1
Nfkbie'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
8.18 × 10-41.1
Nfkbie'Adjuvant System 03' vs 'PBS' in 'hindlimb muscle' at '4 hour'organism part, stimulus, timeExpression data from draining lymph node and muscle of mice immunised with AS03 or PBS
Adjusted p-valueLog2-fold change
1.8225 × 10-31.1
Nfkbie'PLAT knockout; SARS MA15; 7 day' vs 'PLAT knockout; mock'genotype, infect, timeSARS infection of C57BL6, and PLAT knock-out mice
Adjusted p-valueLog2-fold change
1.9759 × 10-31.1
Nfkbie'transgenic C3(1)-SV40Tag; 16 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
2.5165 × 10-31.1
Nfkbie'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.9305 × 10-31.1
Nfkbie'transgenic C3(1)-SV40Tag; 12 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
4.7642 × 10-31.1
Nfkbie'acute graft vs. host disease' vs 'normal'compound, diseaseTranscription profiling by array of murine thymus medulla in the absence and presence of acute graft-versus-host disease
Adjusted p-valueLog2-fold change
6.993 × 10-3-1.1
Nfkbie'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
9.1709 × 10-3-1.1
Nfkbie'Nrf knockout; air; 2 day' vs 'control; air; 2 day'genotype, growth condition, timeGene expression profile of NRf knockout newborn rodents exposed to hyperoxia
Adjusted p-valueLog2-fold change
1.5554 × 10-2-1.1
Nfkbie'dorsolateral nucleus motor neuron' vs 'lumbar motor neurons'cell typeComparison of gene expression in motor pools with differential vulnerability in ALS
Adjusted p-valueLog2-fold change
1.797 × 10-21.1
Nfkbie'colitis' at '19 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
1.8911 × 10-2-1.1
Nfkbie'Id3 knockout' vs 'wild type' in 'Tet+CD24-CD44+NK1.1- Invariant natural killer T'cell type, genotypeEssential functions for ID proteins at multiple checkpoints in natural killer T cell development
Adjusted p-valueLog2-fold change
2.3237 × 10-21.1
Nfkbie'SARS coronavirus MA15; 10^3 PFU' vs 'none' at '7 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
2.7463 × 10-21.1
Nfkbie'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '7 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
2.7673 × 10-21.1
Nfkbie'extensive self renewing erythroblast' vs 'restrictive self renewing erythroblast'cell typeRestrictive and extensively self-renewing erythroblast
Adjusted p-valueLog2-fold change
4.8024 × 10-21.1
Nfkbie'Akt1 -/-' vs 'wild type'genotypeTranscription profiling by array of mouse mammary glands at postnatal day 70 in Akt1 wildtype and Akt1 deficient mice
Adjusted p-valueLog2-fold change
1.3332 × 10-45-1
Nfkbie'KRASG12D' vs 'wild type genotype'genotypeRNA-Seq of murine trisomic B cell precursors expressing KRAS_G12D
Adjusted p-valueLog2-fold change
4.901 × 10-101
Nfkbie'Aatf homozygous knockout' vs 'wild type genotype'genotypeRNA-seq experiment to investigate the effect of inactivating the Apoptosis Antagonizing Transcription Factor (Aatf)
Adjusted p-valueLog2-fold change
2.6127 × 10-8-1
Nfkbie"muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP negative"organism part, phenotypeBulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages
Adjusted p-valueLog2-fold change
1.4031 × 10-61
Nfkbie'6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.4765 × 10-6-1
Nfkbie'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
2.6063 × 10-61
Nfkbie'anti-CD3/anti-CD28' vs 'none' in 'FOXP3 overexpression'genotype, stimulusTranscription profiling by array of FOXP3 overexpression in resting and activated mouse CD4+ T cells
Adjusted p-valueLog2-fold change
1.3989 × 10-51
Nfkbie'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '4 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
1.5129 × 10-51
Nfkbie'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.5459 × 10-51
Nfkbie'lung carcinoma' vs 'normal' in 'lung cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
2.3039 × 10-51
Nfkbie'ATF3 -/-' vs 'wild type' in '10 nanogram per milliliter; lipopolysaccharide' at '2 hour'compound, genotype, timeTranscription profiling by array of mouse bone marrow macrophages mutant for ATF3 after treatment with lipopolysaccharide
Adjusted p-valueLog2-fold change
2.7744 × 10-51
Nfkbie'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
3.0227 × 10-5-1
Nfkbie'induce erythroid differentiation' vs 'none' in 'wild type'genotype, stimulusTranscription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor
Adjusted p-valueLog2-fold change
1.1208 × 10-41
Nfkbie'chronic DSS-induced colitis; 1x DSS, recovery' vs 'none; none'clinical treatment, diseaseTranscription profiling by array of colon tissues isolated from mice with acute and chronic dextran sodium sulphate (DSS)-induced colitis
Adjusted p-valueLog2-fold change
1.1504 × 10-41
Nfkbie'chronic cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
1.4412 × 10-41
Nfkbie'trehalose dimycolated (TDM)' at '2 hour' vs 'phosphatidylglycerol (PG) control' at '2 hour'stimulus, timeTranscription profiling by array of mouse bone marrow-derived macrophages stimulated by trehalose dimycolated (TDM) or phosphatidylglycerol (PG) control to study how mycobacterial TDM reprograms macrophage global gene expression
Adjusted p-valueLog2-fold change
1.7333 × 10-41
Nfkbie'STAT1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '9 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
2.2751 × 10-41
Nfkbie'SARS coronavirus MA15' vs 'none' in 'STAT1 -/-' at '5 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
2.3793 × 10-41
Nfkbie'SARS coronavirus MA15' vs 'none' in 'Tnfrsf1a/1b -/-' at '7 day'genotype, infect, timeSM015 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1a/1b knockouts
Adjusted p-valueLog2-fold change
7.6947 × 10-41
Nfkbie'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day'genotype, infect, timeSM015 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1a/1b knockouts
Adjusted p-valueLog2-fold change
7.6962 × 10-41
Nfkbie'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
7.9383 × 10-41
Nfkbie'methionine- and choline-deficient, high fat diet' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
1.9977 × 10-31
Nfkbie'curdlan' vs 'none' in 'IL2 knockout'compound, genotypeDendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway
Adjusted p-valueLog2-fold change
3.062 × 10-31
Nfkbie'6 day' vs '0 day'timeTranscription profiling by array of mouse colon tissues under dextran sodium sulphate induction for 2, 4 and 6 days against uninduced controls at day 0
Adjusted p-valueLog2-fold change
3.2759 × 10-31
Nfkbie'SARS coronavirus MA15 dORF6' vs 'none' at '4 day'infect, timeSM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course
Adjusted p-valueLog2-fold change
3.5257 × 10-31
Nfkbie'doxycicline-mediated expression of c-Jun' vs 'control'phenotypeTranscription profiling by array of mouse whole bone marrow after c-Jun induction
Adjusted p-valueLog2-fold change
4.706 × 10-31
Nfkbie'missense mutation (T2996C) in Mucin 2 (Muc2)' vs 'wild type genotype'genotypeTranscription profiling of mouse intestine in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
Adjusted p-valueLog2-fold change
5.0776 × 10-31
Nfkbie'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
5.3586 × 10-31
Nfkbie'smoke; 1500 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
6.7995 × 10-31
Nfkbie'Tfc knockout; normal' vs 'control'disease, genotypeGene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor.
Adjusted p-valueLog2-fold change
7.4617 × 10-31
Nfkbie'TMEV infected' at '98 day' vs 'mock control' at '98 day'disease, timeTranscription profiling of mouse spinal cord from mock-infected and Theilers murine encephalomyelitis (TME)-virus infected animals - time series
Adjusted p-valueLog2-fold change
1.1145 × 10-21
Nfkbie'smoke; 2250 microgram' vs 'control; 0 microgram' in 'Nrf2 knockout' at 'after 5 month exposure'compound, genotype, sampling time pointTranscription profiling by array of Nrf2 knockout mice exposed to cigarette smoke
Adjusted p-valueLog2-fold change
1.6211 × 10-2-1
Nfkbie'dox-induced over-expression of oncogenes for 5 days then off 7 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
1.8182 × 10-21
Nfkbie'interleukin-36 alpha and beta and gamma' vs 'none'stimulusTranscriptional profiling of long-term stimulated primary murine intestinal fibroblasts with interleukin-36.
Adjusted p-valueLog2-fold change
1.8705 × 10-21
Nfkbie'colitis' at '12 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
4.8193 × 10-2-1
Nfkbie'Nr4a1 Nr4a3 double knockout' vs 'wild type genotype'genotypeExpression data of mouse hematopoietic cells, Nr4a1/3 wild type and double mutant
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4846130, 5466119, 5524910, 1458299_s_at, 5338027, 10445412, ILMN_1238752, A_51_P235123, 17337927, 107985_at, 101727_at, 5427946, 5080768, 4459949, 5415474, ILMN_2690551, 1431843_a_at, 4677337, 4712319
Reactome pathway ID