-4.2 | | Opn3 | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
3.3 | | Opn3 | 'Duchenne muscular dystrophy' vs 'normal' | disease | RNA-seq comparison of immortalised myoblasts from dystrophic and WT mice |
3.2 | | Opn3 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-2.8 | | Opn3 | 'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
-2.8 | | Opn3 | 'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week' | age, genotype | Prevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA |
-2.4 | | Opn3 | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
2.4 | | Opn3 | 'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-2.4 | | Opn3 | '70 week' vs '6 week' in 'none; none; | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
-2.2 | | Opn3 | 'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
2.2 | | Opn3 | 'Tet2 knockout' vs 'wild type' in 'hematopoietic stem cell' | cell type, genotype | Transcription profiling by high throughput sequencing of bone marrow stem and progenitor cells from Tet2 depleted mice |
-2.2 | | Opn3 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
2.1 | | Opn3 | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
2.1 | | Opn3 | 'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
-2.1 | | Opn3 | 'Yin Yang 1 adipose tissue specific deletion' vs 'wild type phenotype' | phenotype | Brown fat-specific YY1 deficiency effect on subcutaneous white adipose tissue |
2 | | Opn3 | 'Trichuris muris' vs 'control' in 'non wormy; caecum' | environmental stress, infect, organism part | RNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris |
2 | | Opn3 | 'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.9 | | Opn3 | 'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1.9 | | Opn3 | 'Id2_Id3_double knockout' vs 'wild type' in 'CD4+TCRb+CD8– cell; thymus' | cell type, genotype, organism part | Transcription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells |
-1.9 | | Opn3 | '30 month' vs '5 month' in 'male' | age, block, sex | Expression data from tail skin in young (5 months) and old (30 months) CB6F1 mice |
-1.8 | | Opn3 | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
1.8 | | Opn3 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.8 | | Opn3 | 'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
-1.8 | | Opn3 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.8 | | Opn3 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.7 | | Opn3 | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'inguinal fat pad' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
1.7 | | Opn3 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
1.7 | | Opn3 | 'Fhl1 knockdown by siRNA' vs 'wild type' at '3 day' | phenotype, time | 3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1 |
-1.6 | | Opn3 | 'clear cell sarcoma; Rosa26CreER' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.6 | | Opn3 | 'cut nerve; 7 day' vs 'none' | injury, protocol, time | Changes in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury |
1.6 | | Opn3 | '21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
1.6 | | Opn3 | 'CKIαΔgut/p53R172H' vs 'CKIαΔgut/p53Δgut' in 'jejunum' | compound, genotype, organism part | RNAseq of enterocytes of the jejunum and Ileum from transgene C57BL/6 mice harboring a CKIαΔgut knock-out |
1.5 | | Opn3 | 'Cnot3 knockout' vs 'wild type' | phenotype | RNA-seq of mouse islets from Ins1-cre driven Cnot3 KO and control islets |
1.5 | | Opn3 | 'old neuronal stem cells' vs 'young neuronal stem cells' | age | A mechanism for the segregation of age in mammalian neural stem cells |
1.4 | | Opn3 | 'pabpn1l -/-' vs 'wild type genotype' in 'zygote' | genotype, organism part | RNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice |
1.4 | | Opn3 | 'Stat5abfl/fl;MMTV-Cre' vs 'wild type' at 'pregnancy' | genotype, sampling time point | Transcription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy |
-1.4 | | Opn3 | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1.4 | | Opn3 | 'dexamethasone; 1 micromolar' vs 'none' | compound | RNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS |
-1.4 | | Opn3 | 'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
1.4 | | Opn3 | 'TGFβ, 5 nanogram per milliliter' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
1.4 | | Opn3 | 'Tumor Necrosis Factor' vs 'none' | stimulus | Transcription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor |
1.4 | | Opn3 | 'tumor' vs 'normal' in 'liver' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-1.4 | | Opn3 | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-1.4 | | Opn3 | 'inh-alpha/Tag transgenic' vs 'wild type' in 'none' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
1.4 | | Opn3 | '21 percent oxygen, 37 degree Celsius, no serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
1.3 | | Opn3 | 'Trim24,Trp53 double knockdown' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of mouse embryonic stem cells following Trim24 and/or p53 knockdown |
-1.3 | | Opn3 | 'dexamethasone (1 μM) and GW7647 (0.5 μM)' vs 'none' | compound | RNA-seq of primary hepatocytes treated with GR and PPARalpha agonists in the presence of LPS |
-1.3 | | Opn3 | 'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1.3 | | Opn3 | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.3 | | Opn3 | 'LDB1 knock-down with full-length Ldb1 construct' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
-1.3 | | Opn3 | 'LDB1 knock-down' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
1.2 | | Opn3 | 'induced neuronal cell' vs 'pluripotent embryonic stem cell' | phenotype | Transcription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells |
-1.2 | | Opn3 | 'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1.2 | | Opn3 | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
1.2 | | Opn3 | 'tumor' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-1.2 | | Opn3 | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'white adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1.2 | | Opn3 | 'Nippostrongylus brasiliensis' vs 'none' | infect | RNAseq of small intestinal epithelium extracted from mice infected with Nippostrongylus brasiliensis |
-1.2 | | Opn3 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.1 | | Opn3 | 'LKB1 knockout; floxed LKB1 with RIP-Cre' vs 'floxed LKB1 without RIP-Cre; wild type' | genotype, phenotype | Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice |
-1.1 | | Opn3 | 'West Nile virus; late stage encephalitis' vs 'mock infection' | infect, time | Transcriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection |
-1.1 | | Opn3 | 'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1.1 | | Opn3 | 'West Nile virus; late stage encephalitis' vs 'early stage encephalitis' | infect, time | Transcriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection |
-1.1 | | Opn3 | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-1.1 | | Opn3 | 'Abcc8-/-' vs 'wild type genotype' in 'normal; female' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
-1.1 | | Opn3 | 'Abcc8-/-' vs 'wild type genotype' in 'high fat; male' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
-1.1 | | Opn3 | 'acute graft vs. host disease' vs 'normal' | compound, disease | Transcription profiling by array of murine thymus medulla in the absence and presence of acute graft-versus-host disease |
1.1 | | Opn3 | 'Mettl6 knockout clone D1' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
1.1 | | Opn3 | 'HoxA11 HoxD11 null' vs 'wild type' in 'metanephric mesenchyme' | genotype, organism part | Transcription profiling by array of wild type and HoxA11 metenephric mesenchyme and ureteric bud from embryonic day 11.5 mice |
-1.1 | | Opn3 | 'Irx3 knockout' vs 'control' at '7 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
-1.1 | | Opn3 | '19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '5 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
-1 | | Opn3 | 'interleukin-22 (Mus Musculus); 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1 | | Opn3 | '0.45 micromolar; 5-fluourouracil' vs 'none' at '24 hour' | compound, time | Transcription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid |
-1 | | Opn3 | 'adipose tissue specific Trim28 knockout' vs 'wild type genotype' in 'male' | genotype, sex | RNA-seq of gonadal adipose tissue from male and female Trim28-WT and Trim28 adipose specific KO mice |
-1 | | Opn3 | 'Stella maternal / zygotic knockout' vs 'wild type genotype' in '1-cell embryo' | developmental stage, genotype | Transcription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development |
-1 | | Opn3 | 'CHOP-/-' vs 'wild type' in 'DMSO' | compound, genotype | Microarray to find CHOP dependent genes in response to proteasome inhibition |
1 | | Opn3 | '4 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-1 | | Opn3 | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
1 | | Opn3 | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
1 | | Opn3 | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
1 | | Opn3 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1 | | Opn3 | 'Crx knockout' vs 'control' at '6 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
-1 | | Opn3 | 'Abcc8-/-' vs 'wild type genotype' in 'high fat; female' | diet, genotype, sex | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
1 | | Opn3 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Opn3 | 'Mettl6 knockout clone G6' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
1 | | Opn3 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Opn3 | 'beta cell specific Pax6 knockout' vs 'wild type' | phenotype | RNA-Seq of pancreatic islets from beta cell-specific Pax6 knockout mice |
1 | | Opn3 | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-1 | | Opn3 | 'MEF2A knockout' vs 'wild type genotype' in 'Hoxb8-FL; none' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |