ensmusg00000030744 (Rps3)

mus musculus

ribosomal protein S3

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Mus musculus
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Showing 29 experiments:
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Created with Highcharts 6.2.0adrenal glandbraincerebral cortexdorsal control neural epitheliumheartlateral nasal prominencemedial nasal prominenceolfactory bulbprostate glandstriatumtracheazone of skinaxillary lymph nodecaecumcorpus striatumepididymis and seminiferous tubuleintestinal mucosalungmuscle (biceps femoris)pancreasspinal cordtestisvagina
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9 in 3 strains - CD1
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9
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9 in 3 strains - DBA/2J
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9 in 3 strains - C57BL/6
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Mammalian Kaessmann
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Vertebrates
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49 FANTOM5 project - adult
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3 Soumillon et al
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - C57BL/6J
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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3
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14 - embryonic day 10.5
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4 Bonthuis et al - Idaho derived wild …
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Organism part - Huttlin et al
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Huttlin et al., 2010 - tissues - brain, …
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Proteomics
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Transcriptomics
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-1
-4.6
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.7728 × 10-4-4.6
Rps3'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
4.8112 × 10-7-4.4
Rps3'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+'compound, genotypePolycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos)
Adjusted p-valueLog2-fold change
1.0098 × 10-1134
Rps3'pabpn1l -/-' vs 'wild type genotype' in 'zygote'genotype, organism partRNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice
Adjusted p-valueLog2-fold change
6.7059 × 10-3-3.3
Rps3'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.255 × 10-4-2.3
Rps3'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.4286 × 10-13-2.1
Rps3'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
6.7689 × 10-4-2.1
Rps3'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
3.4455 × 10-6-2
Rps3'polarized with E coli lipopolysacharide and INF-gamma' vs 'untreated'compound, treatmentExpression data from polarized macrophages: effect of p53
Adjusted p-valueLog2-fold change
3.5392 × 10-61.9
Rps3'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.7838 × 10-31.9
Rps3'AhCre Apc Floxed Cited1 knockout' vs 'control'genotypeCited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis
Adjusted p-valueLog2-fold change
1.4455 × 10-21.9
Rps3'AhCre Apc Floxed' vs 'control'genotypeCited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis
Adjusted p-valueLog2-fold change
1.7268 × 10-58-1.8
Rps3'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
2.0945 × 10-71.7
Rps3'2'-fucosyllactose supplementation' vs 'control' in '8 weeks post-ileocecal resection'diet, treatmentTranscriptomic characterization of the impact of 2'-fucosyllactose supplementation on intestinal adaptation following ileocecal resection.
Adjusted p-valueLog2-fold change
1.6292 × 10-41.7
Rps3'spontaneous lung tumor' vs 'normal'disease state, diseaseTranscription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer
Adjusted p-valueLog2-fold change
5.8701 × 10-81.6
Rps3'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
3.8202 × 10-6-1.6
Rps3'Lactobacillus acidophilus NCFM and Bifidobacterium bifidum Z9' vs 'control'infectTranscription profiling by array of mouse dendritic cells after infection with Bifidobacterium bifidum and Lactobacillus acidophilus
Adjusted p-valueLog2-fold change
4.4832 × 10-61.6
Rps3'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
7.5662 × 10-61.6
Rps3'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
8.3809 × 10-61.6
Rps3'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.6225 × 10-51.6
Rps3'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.6361 × 10-5-1.6
Rps3'granulocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
2.3557 × 10-4-1.6
Rps3'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
1.353 × 10-21.6
Rps3'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'control; 36 hour after partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
2.6748 × 10-71-1.5
Rps3'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
6.4033 × 10-81.5
Rps3'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.5359 × 10-61.5
Rps3'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
7.7904 × 10-6-1.5
Rps3'Lactobacillus acidophilus NCFM' vs 'control'infectTranscription profiling by array of mouse dendritic cells after infection with Bifidobacterium bifidum and Lactobacillus acidophilus
Adjusted p-valueLog2-fold change
2.0489 × 10-51.5
Rps3'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.0289 × 10-5-1.5
Rps3'Lin- Dapi-EpCAM- CD31+td-tomato+' vs 'Lin- Dapi-EpCAM- CD31+td-tomato-' in 'vascular endothelial cell'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
6.9483 × 10-4-1.5
Rps3'subventicular zone of the lateral ventricle' vs 'cerebellum'organism partExpression data from adult Shh-responding astroglia cells in mice
Adjusted p-valueLog2-fold change
7.6238 × 10-39-1.4
Rps3'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
6.7327 × 10-12-1.4
Rps3'12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
4.7437 × 10-61.4
Rps3'methionine- and choline-deficient, high fat diet mixed with 0.1% metformin' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
1.9079 × 10-51.4
Rps3'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.5538 × 10-51.4
Rps3'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.3894 × 10-4-1.4
Rps3'dominant active mutant DREAM transgenic' vs 'wild type'genotypeTranscription profiling by array of hippocampus from transgenic mice expressing a Ca2+-insensitive/CREB-independent dominant active mutant DREAM
Adjusted p-valueLog2-fold change
1.7467 × 10-41.4
Rps3'CCl4; 1.6 gram per kilogram' at '24 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
4.1496 × 10-41.4
Rps3'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
1.5271 × 10-3-1.4
Rps3'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha'genotype, stimulusRNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment
Adjusted p-valueLog2-fold change
2.7711 × 10-91.3
Rps3'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day'compound, phenotype, timeRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
Adjusted p-valueLog2-fold change
1.7558 × 10-61.3
Rps3'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
4.8332 × 10-51.3
Rps3'confluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.8213 × 10-5-1.3
Rps3'Bifidobacterium bifidum Z9' vs 'control'infectTranscription profiling by array of mouse dendritic cells after infection with Bifidobacterium bifidum and Lactobacillus acidophilus
Adjusted p-valueLog2-fold change
1.1943 × 10-31.3
Rps3'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
4.9492 × 10-31.3
Rps3'Tfc knockout; thymic lymphoma' vs 'control'disease, genotypeGene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor.
Adjusted p-valueLog2-fold change
3.9523 × 10-43-1.2
Rps3'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
3.0591 × 10-14-1.2
Rps3'LDB1 knock-down with full-length Ldb1 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
2.0568 × 10-61.2
Rps3'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
3.248 × 10-6-1.2
Rps3'none; wasp knockout' vs 'none; wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
1.3581 × 10-31.2
Rps3'Taf10-/-' vs 'wild type'genotypeTranscription profiling by array of liver from Taf10 knock out mice
Adjusted p-valueLog2-fold change
1.2947 × 10-41.1
Rps3'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.9923 × 10-41.1
Rps3'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.373 × 10-41.1
Rps3'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
7.6641 × 10-4-1.1
Rps3'NOD' vs 'C57BL/6' in 'steady state' at '0 hour'strain, time, treatmentExpression data from NOD and C57BL/6 mouse pancreas CD8α- Dendritic Cells (DCs) under steady-state and after in-vitro LPS stimulation
Adjusted p-valueLog2-fold change
8.3115 × 10-3-1.1
Rps3'9V/null' vs 'wild type' in 'saline; spleen'compound, genotype, organism partGaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Mouse Model Treated with velaglucerase alfa or imiglucerase [RNA-Seq]
Adjusted p-valueLog2-fold change
9.7933 × 10-31.1
Rps3'12 hour' vs '0 hour' on 'Affymetrix MOE430B Array'timeTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
3.6349 × 10-21.1
Rps3'neuronal stem cell; positive staining for GFP and prominin' vs 'astrocyte; positive staining for GFP'cell type, phenotypeTranscription profiling by array of adult neural stem cells (hGFAP-GFP+/prominin1+ cells) compared to parenchymal astrocytes that are not neurogenic (hGFAP-GFP+ cells from the diencephalon)
Adjusted p-valueLog2-fold change
4.1949 × 10-21.1
Rps3"Evi1-GFP positive" vs "Evi1-GFP negative"phenotypeWhole genome expression profiling of Evi1-GFP positive and negative murine hematopoietic stem cell sub-populations.
Adjusted p-valueLog2-fold change
1.9318 × 10-25-1
Rps3'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.1794 × 10-131
Rps3'epithelium-specific mutant beta-catenin expression' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
3.1929 × 10-6-1
Rps3'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
3.7713 × 10-6-1
Rps3'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
6.6791 × 10-61
Rps3'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.7394 × 10-51
Rps3'methionine- and choline-deficient, high fat diet' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
8.268 × 10-5-1
Rps3'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
1.1806 × 10-41
Rps3'mutant MyoD expression' at '6 hour' vs 'control' at '6 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
2.8313 × 10-4-1
Rps3'trichostatin A and LIF' at '12 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
6.315 × 10-41
Rps3'18 hour' vs '0 hour' on 'Affymetrix MOE430B Array'timeTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
7.2882 × 10-41
Rps3'HDAC4het' vs 'wild type genotype'genotypeGene expression data from cortex of 15 week old wild type, R6/2, HDAC4het and R6/2::HDAC4het mice
Adjusted p-valueLog2-fold change
1.8566 × 10-31
Rps3'PS2APP transgenic' vs 'non transgenic' in 'microglia cell' at '13 month'age, cell type, genotypeTranscription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model
Adjusted p-valueLog2-fold change
3.2105 × 10-31
Rps3'96 hour' vs '0 hour' on 'Affymetrix MOE430B Array'timeTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
4.5445 × 10-31
Rps3'doxycicline-mediated expression of c-Jun' vs 'control'phenotypeTranscription profiling by array of mouse whole bone marrow after c-Jun induction
Adjusted p-valueLog2-fold change
1.9018 × 10-21
Rps3'eIF6+/-' vs 'wild type genotype'genotypeRNA-seq of liver biopsies of eIF6 wild type and eIF6 heterozygous mice
Adjusted p-valueLog2-fold change
2.5374 × 10-21
Rps3'cardiotoxin; 10 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq comparison of fibro-adipogenic progenitors (FAPs) from wild type, mdx and cardiotoxin-injured mice
Adjusted p-valueLog2-fold change
2.7137 × 10-2-1
Rps3'induction of polymicrobial sepsis' vs 'control' at '2 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
2.7977 × 10-2-1
Rps3'malignant peritoneal mesothelioma; hi SV40 virus large TAg genotype (hiTAg)' vs 'malignant peritoneal mesothelioma; wild type genotype'disease, genotypeGene expression profiles in MexTAg transgenic mouse and wild type mouse asbestos-induced mesothelioma
Adjusted p-valueLog2-fold change
4.087 × 10-21
Rps3'Tet2 knockout' vs 'wild type' in 'hematopoietic stem cell'cell type, genotypeTranscription profiling by high throughput sequencing of bone marrow stem and progenitor cells from Tet2 depleted mice
Adjusted p-valueLog2-fold change
4.6998 × 10-21
Rps3'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Synonym
D7Ertd795e
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
1455600_at, aa265222_s_at, A_52_P768, 4358421, 10565802, 101137_at, 4468524, 4423540, ILMN_2594103, ILMN_2637639, 4929796, 4337319, A_55_P2038237, 17493668, X76772_f_at
Reactome pathway ID
Nonsense-Mediated Decay (NMD), Eukaryotic Translation Initiation, Ribosomal scanning and start codon recognition, L13a-mediated translational silencing of Ceruloplasmin expression, Metabolism of RNA, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC), Translation, rRNA processing in the nucleus and cytosol, Major pathway of rRNA processing in the nucleolus and cytosol, rRNA processing, SRP-dependent cotranslational protein targeting to membrane, Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, Translation initiation complex formation, Formation of a pool of free 40S subunits, GTP hydrolysis and joining of the 60S ribosomal subunit, Metabolism of proteins, Formation of the ternary complex, and subsequently, the 43S complex, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC), Cap-dependent Translation Initiation