ensmusg00000024091 (Vapa)

mus musculus

vesicle-associated membrane protein, associated protein A

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Mus musculus
Organism part
Showing 24 experiments:
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Created with Highcharts 6.2.0arcuate nucleus of hypothalamusbrainbrown adipose tissuecaudal brain neural epitheliumcerebellumdentate gyrus of hippocampal formationdorsal raphe nucleusfloor plateheartileumkidneylateral prominence neural epitheliumlungmaxillary archmedial prefrontal cortexmuscle tissueolfactory bulbolfactory pitskeletal muscle tissuestriatumtestistracheawhite adipose tissue
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9 in 3 strains - CD1
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9 in 3 strains - DBA/2J
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9 in 3 strains - C57BL/6
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14 - embryonic day 10.5
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Mammalian Kaessmann
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9
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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Fat and muscle
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3 Soumillon et al
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Sun et al., 2020 - Organism part
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4 Bonthuis et al - (CastEiJ X …
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Mernberger et al 2019 - Organism Part
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Developing gut
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4 Bonthuis et al - C57BL/6J
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4 Bonthuis et al - (C57BL/6J X …
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Vertebrates
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3
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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4 Bonthuis et al - CastEiJ
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Proteomics
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Transcriptomics
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Regulation
-1.1
-5.8
1
1.4
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
7.4966 × 10-7-5.8
Vapa'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
4.7451 × 10-8-1.6
Vapa'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
4.8959 × 10-4-1.6
Vapa'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha'genotype, stimulusRNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment
Adjusted p-valueLog2-fold change
2.0216 × 10-2-1.6
Vapa'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
1.4216 × 10-4-1.4
Vapa'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
8.6593 × 10-4-1.4
Vapa'Fhl1 knockdown by siRNA' vs 'wild type' at '1 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
1.9762 × 10-21.4
Vapa'interferon gamma; 1 nanogram per milliliter' vs 'none'stimulusAnalysis of transcriptomes in intestinal stem cells in response to Interferon gamma
Adjusted p-valueLog2-fold change
2.2245 × 10-61.3
Vapa'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.7107 × 10-3-1.3
Vapa'Mxd1 knockdown by siRNA' vs 'wild type' at '1 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
3.7378 × 10-21.3
Vapa'4 hours after hCG treatment' vs 'control' in 'wild type'genotype, treatmentThe ISWI ATPase Snf2L is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells
Adjusted p-valueLog2-fold change
3.1538 × 10-73-1.2
Vapa'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
2.3946 × 10-371.2
Vapa'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.9642 × 10-5-1.2
Vapa'UO126; 0.2 milligram per kilogram; miR-1-133a_dKO' vs 'miR-1-133a_dKO'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
8.9501 × 10-4-1.2
Vapa'miR-1-133a_OSMR_tKO' vs 'miR-1-133a_dKO'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
1.1396 × 10-3-1.2
Vapa'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
5.1377 × 10-641.1
Vapa'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
3.148 × 10-91.1
Vapa'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.5969 × 10-81.1
Vapa'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.2404 × 10-5-1.1
Vapa'PGC-1 beta knock in' vs 'wild type'genotypeTranscription profiling by array of skeletal muscle from PGC-1 beta transgenic mice
Adjusted p-valueLog2-fold change
1.0809 × 10-4-1.1
Vapa'miR-1-133a_FGFR1_tKO' vs 'miR-1-133a_dKO'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
1.4339 × 10-41.1
Vapa'Staphylococcus aureus Sanger476; 6 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
3.567 × 10-2-1.1
Vapa'24 hour' vs '4 hour'timeTranscription profiling of mouse rhythmic mRNA expression in the distal colon
Adjusted p-valueLog2-fold change
4.9595 × 10-2-1.1
Vapa'Cebpa L/L mutant' vs 'wild type'genotypeTranscription profiling by array of mouse LSK hematopoietic stem cells from Cebpa K/K, K/L, and L/L knock-in mutants
Adjusted p-valueLog2-fold change
1.3232 × 10-341
Vapa'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
4.0113 × 10-281
Vapa'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout'infect, phenotypeWhole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach
Adjusted p-valueLog2-fold change
1.6818 × 10-171
Vapa'SARS coronavirus MA15; 2 day' vs 'mock' in 'C57BL/6J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.5269 × 10-61
Vapa'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
4.2197 × 10-61
Vapa'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.634 × 10-51
Vapa'collagen sandwich' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.8235 × 10-41
Vapa'interferon beta' vs 'none' in 'wild type; uninfected'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
5.821 × 10-41
Vapa'fear conditioning' vs 'none'stimulusGene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage