ensmusg00000006373 (Pgrmc1)

mus musculus

progesterone receptor membrane component 1

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Mus musculus
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
4.1819 × 10-6-6.9
Pgrmc1'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
5.6557 × 10-5-4.2
Pgrmc1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.276 × 10-82-3.2
Pgrmc1'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.1716 × 10-7-2.8
Pgrmc1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
3.1343 × 10-8-2.3
Pgrmc1'induced neural stem cell' vs 'mouse embryonic fibroblast cell'cell typeGene expression profile of mouse induced neural stem cells
Adjusted p-valueLog2-fold change
7.6185 × 10-78-2.2
Pgrmc1'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
8.8214 × 10-5-2.2
Pgrmc1'spontaneous lung tumor' vs 'normal'disease state, diseaseTranscription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer
Adjusted p-valueLog2-fold change
5.0746 × 10-1182.1
Pgrmc1'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
3.4796 × 10-752.1
Pgrmc1'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
2.18 × 10-41-2.1
Pgrmc1'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
3.0918 × 10-32
Pgrmc1'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
6.4654 × 10-3-2
Pgrmc1'subventicular zone of the lateral ventricle' vs 'cerebellum'organism partExpression data from adult Shh-responding astroglia cells in mice
Adjusted p-valueLog2-fold change
1.1501 × 10-3-1.9
Pgrmc1'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs'growth conditionRNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs
Adjusted p-valueLog2-fold change
8.9885 × 10-3-1.9
Pgrmc1'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 15.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
3.5542 × 10-131.8
Pgrmc1'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.791 × 10-81.8
Pgrmc1'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal'diseaseTranscription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma
Adjusted p-valueLog2-fold change
2.5111 × 10-3-1.8
Pgrmc1'neural stem cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
3.097 × 10-12-1.7
Pgrmc1'KrasG12D' vs 'wild type'genotypeAn oncogenic Kras expression signature identified by cross-species
Adjusted p-valueLog2-fold change
1.0553 × 10-9-1.6
Pgrmc1'MEF; transduced with MyoD lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
1.6079 × 10-6-1.6
Pgrmc1'carotid body' vs 'adrenal medulla'organism partExpression profile of mouse carotid body and adrenal medulla [RNA-Seq]
Adjusted p-valueLog2-fold change
2.9356 × 10-5-1.6
Pgrmc1'granulocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
2.9204 × 10-2-1.6
Pgrmc1'neural progenitor cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
9.2672 × 10-201.5
Pgrmc1'upf3 knockout' vs 'wild type' in 'testis'cell type, genotypeUPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs
Adjusted p-valueLog2-fold change
1.5414 × 10-141.5
Pgrmc1'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
2.2985 × 10-61.5
Pgrmc1'acute myeloid leukemia' vs 'myeloproliferative disorder'diseaseTranscription profiling by high throughput sequencing of c-KIT+ splenocytes from murine acute myeloid leukemia and myeloproliferative neoplasm
Adjusted p-valueLog2-fold change
3.5936 × 10-2-1.5
Pgrmc1'24 hour' vs '4 hour'timeTranscription profiling of mouse rhythmic mRNA expression in the distal colon
Adjusted p-valueLog2-fold change
1.4649 × 10-29-1.4
Pgrmc1'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.2413 × 10-271.4
Pgrmc1'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
4.8491 × 10-17-1.4
Pgrmc1'epithelium-specific Apc knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
1.5312 × 10-31.4
Pgrmc1'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
3.0855 × 10-31.4
Pgrmc1'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.8141 × 10-2-1.4
Pgrmc1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.6809 × 10-311.3
Pgrmc1'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.9658 × 10-25-1.3
Pgrmc1'extracellular vesicle; MET cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
4.9846 × 10-11-1.3
Pgrmc1'MyD88 homozygous knockout' vs 'wild type genotype' in 'TLR9 ligand CpG ODN (1826)'genotype, stimulusTranscription profiling by sequencing of murine MyD88 -/- and MyD88 +/+ mTECs stimulated with a TLR9 ligand
Adjusted p-valueLog2-fold change
1.3867 × 10-6-1.3
Pgrmc1'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.9313 × 10-6-1.3
Pgrmc1'mutant MyoD expression' at '24 hour' vs 'control' at '24 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
8.6914 × 10-6-1.3
Pgrmc1'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.2513 × 10-41.3
Pgrmc1'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day'compound, genotype, timeTranscription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin
Adjusted p-valueLog2-fold change
1.6882 × 10-4-1.3
Pgrmc1'myelocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
1.8583 × 10-41.3
Pgrmc1'chemical hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo.
Adjusted p-valueLog2-fold change
3.2749 × 10-31.3
Pgrmc1'calorie restricted diet' vs 'normal diet' at '15 month'age, dietTranscription profiling by array of cochleae from mice fed a calorie-restricted diet
Adjusted p-valueLog2-fold change
1.7099 × 10-21.3
Pgrmc1'megakaryocyte' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
2.3102 × 10-2-1.3
Pgrmc1'Escherichia coli O18:K1:H7; 2 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
8.1869 × 10-19-1.2
Pgrmc1'epithelium-specific mutant beta-catenin expression' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
1.9817 × 10-71.2
Pgrmc1'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
3.268 × 10-7-1.2
Pgrmc1'Mycobacterium tuberculosis H37Rv' vs 'none' in 'TNF-alpha knockout'compound, genotype, infect4-week mouse comparative study on effect of neutralizing IL-17A, IL-17F and TNFa antibodies
Adjusted p-valueLog2-fold change
1.4749 × 10-6-1.2
Pgrmc1'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.2674 × 10-6-1.2
Pgrmc1'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.3685 × 10-41.2
Pgrmc1'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
1.9267 × 10-21.2
Pgrmc1'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.9397 × 10-2-1.2
Pgrmc1'Ezh2 knockout' vs 'control'genotypeExpression profiling of secondary wild type (WT) and Ezh2-null murine MLL-AF9 AML
Adjusted p-valueLog2-fold change
1.8526 × 10-19-1.1
Pgrmc1'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
8.2087 × 10-17-1.1
Pgrmc1'extracellular vesicle; EMT cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
8.6055 × 10-141.1
Pgrmc1'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
5.149 × 10-12-1.1
Pgrmc1'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.618 × 10-71.1
Pgrmc1'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.0121 × 10-6-1.1
Pgrmc1'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil'cell type, genotypeRNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice
Adjusted p-valueLog2-fold change
5.0281 × 10-6-1.1
Pgrmc1'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.8224 × 10-6-1.1
Pgrmc1'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.2601 × 10-51.1
Pgrmc1'Cbfb knockout' vs 'control of Cbfb knockout'genotypeTranscription profiling by array of Mus musculus expressing Cbfb-MYH11
Adjusted p-valueLog2-fold change
3.4262 × 10-41.1
Pgrmc1'Dicer knockout' vs 'wild type genotype'genotypeTranscription profiling by array of mouse Dicer-knockout CD4 T cells against wild type controls
Adjusted p-valueLog2-fold change
7.8894 × 10-31.1
Pgrmc1'expanded on HUVEC and m5GF in the presence of mD1R for 7 days' vs 'control'treatmentExpression data from cultured c-Kit+Sca-1+Lin- (KSL)cells
Adjusted p-valueLog2-fold change
1.0835 × 10-21.1
Pgrmc1'side population cells' vs 'main population cells' in 'bone marrow'cell type, organism partGene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow
Adjusted p-valueLog2-fold change
1.1158 × 10-2-1.1
Pgrmc1'Tetrafluororethane; 50000 part per million; air' vs 'none; ; air'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
7.2053 × 10-8-1
Pgrmc1'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.2279 × 10-71
Pgrmc1'180 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.5059 × 10-61
Pgrmc1'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
3.0552 × 10-61
Pgrmc1'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
9.0614 × 10-61
Pgrmc1'16 day' vs '0 day'ageGene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26)
Adjusted p-valueLog2-fold change
8.8261 × 10-5-1
Pgrmc1'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
8.9846 × 10-5-1
Pgrmc1'chronic cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
9.1574 × 10-5-1
Pgrmc1'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
9.5213 × 10-5-1
Pgrmc1'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control'phenotypeTemporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice
Adjusted p-valueLog2-fold change
2.3979 × 10-41
Pgrmc1'E2f1, E2f2, E2f3 triple knockout' vs 'control' at 'neonate'developmental stage, genotypeExpression data from lenses triply deficient for E2F1, E2F2, and E2F3 transcription factors
Adjusted p-valueLog2-fold change
4.6902 × 10-4-1
Pgrmc1'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day'cell type, compound, timeDrug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs
Adjusted p-valueLog2-fold change
5.6722 × 10-41
Pgrmc1'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
5.2543 × 10-31
Pgrmc1'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
5.7722 × 10-31
Pgrmc1'infarct and border region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
2.3282 × 10-21
Pgrmc1'colitis' vs 'normal' in 'wild type'compound, disease, genotypeTranscription profiling by array of wild-type or Thrombospondin 1 (TSP-1) null mouse dextran sulphate sodium (DSS)-induced colitis treated with various forms of TSP-1, a protein with regulatory functions in inflammation and cancer
Adjusted p-valueLog2-fold change
2.3913 × 10-21
Pgrmc1"Evi1-GFP positive" vs "Evi1-GFP negative"phenotypeWhole genome expression profiling of Evi1-GFP positive and negative murine hematopoietic stem cell sub-populations.