ensmusg00000030082 (Sec61a1)

mus musculus

Sec61 alpha 1 subunit (S. cerevisiae)

Filter your results

Mus musculus
Organism part
Showing 3 experiments:
Created with Highcharts 6.2.0braincentral neural epitheliumcerebellumdorsal control neural epitheliumepidermal ectodermhead mesenchymeheartkidneylateral nasal prominencelateral prominence neural epitheliumlivermandibular archmaxillary archmedial nasal prominenceolfactory pittestis
P
Proteomics
T
Transcriptomics
High
Medium
Low
Below cutoff
No data available

Filter your results

Kingdom
Species
Experiment type
Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.0034 × 10-303.5
Sec61a1'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
3.8335 × 10-33.4
Sec61a1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.0196 × 10-133
Sec61a1'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal'diseaseTranscription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma
Adjusted p-valueLog2-fold change
1.1755 × 10-42.9
Sec61a1'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
5.365 × 10-252.7
Sec61a1'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
5.9361 × 10-432.5
Sec61a1'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
7.4622 × 10-222.4
Sec61a1'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
4.5627 × 10-282.3
Sec61a1'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
5.2 × 10-4-2.1
Sec61a1'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
1.6313 × 10-201.9
Sec61a1'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
9.0938 × 10-41-1.8
Sec61a1'extracellular vesicle; EMT cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
7.9421 × 10-28-1.7
Sec61a1'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
3.6149 × 10-8-1.5
Sec61a1'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
4.3574 × 10-71.5
Sec61a1'CCl4; 1.6 gram per kilogram' at '24 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
4.4755 × 10-61.5
Sec61a1'transgenic' vs 'wild type' in '121 day; 129Sv'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
1.7432 × 10-41.5
Sec61a1'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
1.5469 × 10-181.4
Sec61a1'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.3677 × 10-14-1.4
Sec61a1'extracellular vesicle; MET cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
7.6248 × 10-61.4
Sec61a1'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
2.8281 × 10-51.4
Sec61a1'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.2412 × 10-31.4
Sec61a1'infarct and border region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ'clinical information, strainExpression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction
Adjusted p-valueLog2-fold change
4.9068 × 10-71.3
Sec61a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
7.3969 × 10-51.3
Sec61a1'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day'compound, genotype, timeTranscription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin
Adjusted p-valueLog2-fold change
1.643 × 10-31.3
Sec61a1'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
1.4193 × 10-21.3
Sec61a1'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
8.7675 × 10-37-1.2
Sec61a1'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
4.9578 × 10-341.2
Sec61a1'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
3.9624 × 10-211.2
Sec61a1'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
1.8792 × 10-171.2
Sec61a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
7.2913 × 10-71.2
Sec61a1'Plasmodium berghei' vs 'none' in 'none'compound, infectTranscription profiling by array of mouse blood infected with Plasmodium berghei after treatment with activated charcoal
Adjusted p-valueLog2-fold change
4.5977 × 10-6-1.2
Sec61a1'hematopoietic stem cell and hematopoietic multipotent progenitor cell' vs 'common myeloid progenitor'cell typeTranscription profiling by high throughput sequencing between multipotent hematopoietic stem progenitor cells LS+K) and myeloid committed cells (LS−K) of the mouse bone marrow
Adjusted p-valueLog2-fold change
1.0782 × 10-41.2
Sec61a1'heart-specific Mdm2 knockout; 14 day' vs 'heart-specific Mdm2 knockout; 7 day'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
1.2067 × 10-41.2
Sec61a1'wild type; treated with angiotensin II and a combination of hydralazine and hydrochlorothiazide' vs 'wild type; vehicle'genotype, treatmentEffect of Hypertension of Dendritic Cell Gene Expression
Adjusted p-valueLog2-fold change
4.6108 × 10-21.2
Sec61a1'induction of polymicrobial sepsis' vs 'control' at '72 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
1.033 × 10-89-1.1
Sec61a1'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.8801 × 10-79-1.1
Sec61a1'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
4.7134 × 10-181.1
Sec61a1'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar'compound, genotypeOverexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment
Adjusted p-valueLog2-fold change
1.9345 × 10-161.1
Sec61a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
5.2575 × 10-101.1
Sec61a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.0815 × 10-7-1.1
Sec61a1'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
2.1868 × 10-7-1.1
Sec61a1'3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
3.9976 × 10-71.1
Sec61a1'Trichuris muris' vs 'control' in 'non wormy; caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
8.8743 × 10-71.1
Sec61a1'seizure-preconditioning followed by intra-amygdala kainic acid' vs 'sham-preconditioning followed by intra-amygdala vehicle'clinical treatmentTranscription profiling by array of mice with epileptic tolerance
Adjusted p-valueLog2-fold change
1.0629 × 10-61.1
Sec61a1'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'A/J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
1.5403 × 10-51.1
Sec61a1'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.8301 × 10-41.1
Sec61a1'Staphylococcus aureus Sanger476; 6 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
2.0344 × 10-4-1.1
Sec61a1'chronic cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
4.8641 × 10-31.1
Sec61a1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
8.9847 × 10-44-1
Sec61a1'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
4.7311 × 10-211
Sec61a1'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
4.6399 × 10-14-1
Sec61a1'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
6.7353 × 10-141
Sec61a1'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
1.4303 × 10-121
Sec61a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.568 × 10-81
Sec61a1'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.008 × 10-71
Sec61a1'CCl4; 1.6 gram per kilogram' at '8 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
5.5865 × 10-7-1
Sec61a1'6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
6.9799 × 10-71
Sec61a1'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
1.0991 × 10-61
Sec61a1'5 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
2.5425 × 10-61
Sec61a1'Staphylococcus aureus Sanger476; 12 hour' vs 'none; 0 hour' in 'C57BL/6J'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Adjusted p-valueLog2-fold change
3.3263 × 10-51
Sec61a1'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day'phenotype, timeTranscription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2
Adjusted p-valueLog2-fold change
1.7387 × 10-41
Sec61a1'Cbfb knockout' vs 'control of Cbfb knockout'genotypeTranscription profiling by array of Mus musculus expressing Cbfb-MYH11
Adjusted p-valueLog2-fold change
4.0649 × 10-41
Sec61a1'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 18.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
2.0331 × 10-3-1
Sec61a1'Pcl2 knockdown' vs 'control'genotypeGene expression profile in mouse embryonic stem cells in which endogenous Pcl2 expression was stably knocked down using short hairpin RNA
Adjusted p-valueLog2-fold change
1.1752 × 10-21
Sec61a1'Pax7 driven ablation of miR-1/133a' vs 'wild type'phenotypeMetabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk-Dio3 mega gene cluster.
Adjusted p-valueLog2-fold change
4.1411 × 10-21
Sec61a1'5 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance