4.1 | | Spryd7 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
3.1 | | Spryd7 | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
2.9 | | Spryd7 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
2.9 | | Spryd7 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.9 | | Spryd7 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
2.8 | | Spryd7 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
2.8 | | Spryd7 | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.7 | | Spryd7 | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
2.6 | | Spryd7 | 'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.6 | | Spryd7 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
2.3 | | Spryd7 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.2 | | Spryd7 | 'granulocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
-2.1 | | Spryd7 | 'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs' | growth condition | RNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs |
2 | | Spryd7 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2 | | Spryd7 | 'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-' | compound, genotype | Inhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2) |
2 | | Spryd7 | 'expanded on HUVEC and m5GF in the presence of mD1R for 7 days' vs 'control' | treatment | Expression data from cultured c-Kit+Sca-1+Lin- (KSL)cells |
-1.9 | | Spryd7 | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
-1.9 | | Spryd7 | 'myelocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
-1.9 | | Spryd7 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.9 | | Spryd7 | 'Lgr6-positive hair follicle/sebaceous gland cell' vs 'Lgr6-positive basal interfollicular epidermis cell' | cell type | Transcription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle |
1.8 | | Spryd7 | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'CD36 knockout' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
-1.7 | | Spryd7 | 'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.7 | | Spryd7 | 'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; STI571 treated' vs 'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; untreated' | cell type, treatment | Gene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice |
1.7 | | Spryd7 | 'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'wild type' | compound, genotype | Inhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2) |
-1.7 | | Spryd7 | 'Bcl6 -/- BCR-ABL1-transformed B cell precursors; STI571 treated' vs 'Bcl6 -/- BCR-ABL1-transformed B cell precursors; untreated' | cell type, treatment | Gene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice |
-1.7 | | Spryd7 | '24 hour' vs '4 hour' | time | Transcription profiling of mouse rhythmic mRNA expression in the distal colon |
-1.6 | | Spryd7 | 'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.6 | | Spryd7 | 'lipopolysaccharide' vs 'none' in 'bone marrow; wild type' | cell type, compound, genotype | Transcription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice |
-1.6 | | Spryd7 | '120 day; Sod1 G93A' vs '120 day; wild type genotype' | age, genotype | Transcription profiling of astrocytes from the symptomatic and late-stage time points of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis (ALS) |
1.5 | | Spryd7 | 'Debaryomyces hansenii' at '6 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
-1.5 | | Spryd7 | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.5 | | Spryd7 | 'clear cell sarcoma; Rosa26CreER' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.5 | | Spryd7 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-1.5 | | Spryd7 | 'transgenic' vs 'wild type' in '121 day; 129Sv' | age, genotype, strain | Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models |
1.5 | | Spryd7 | 'SOD1-G93A transgenic' vs 'wild type' at 'day 130/end-stage' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
-1.5 | | Spryd7 | 'hippocampus' vs 'cerebellum' | organism part | Expression data from adult Shh-responding astroglia cells in mice |
1.5 | | Spryd7 | 'PS2APP transgenic' vs 'non transgenic' in 'microglia cell' at '13 month' | age, cell type, genotype | Transcription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model |
-1.5 | | Spryd7 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.4 | | Spryd7 | 'Debaryomyces hansenii' at '2 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
1.4 | | Spryd7 | 'SARS coronavirus MA15' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1.4 | | Spryd7 | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.4 | | Spryd7 | 'synovial sarcoma' vs 'normal' | disease | Transcription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice |
1.3 | | Spryd7 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.3 | | Spryd7 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.3 | | Spryd7 | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1.3 | | Spryd7 | 'NrlGFP positive' vs 'NrlGFP negative' | phenotype | Transcription profiling by array of photoreceptor precursor cells selected via cell surface antigen expression. |
1.3 | | Spryd7 | 'SARS coronavirus MA15 dORF6' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1.3 | | Spryd7 | 'infarct and border region of left ventricle 5 days post-myocardial infarction; C57BL/6J' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; C57BL/6J' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
-1.3 | | Spryd7 | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1.2 | | Spryd7 | 'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
1.2 | | Spryd7 | 'oxidized low density lipoprotein; 25 microgram per milliliter' vs 'none' in 'wild type genotype' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
-1.2 | | Spryd7 | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
1.2 | | Spryd7 | 'CXCR3 knockout; SARS MA15; 2 day' vs 'CXCR3 knockout; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
1.2 | | Spryd7 | 'SARS coronavirus MA15' vs 'mock' in 'TLR3 knockout' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
-1.2 | | Spryd7 | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
1.2 | | Spryd7 | 'lipid nanoparticle complexed with ribonucleic acid expressing respiratory synctial virus F protein' vs 'phosphate buffered saline' | stimulus | Microarray analysis of mouse whole genome using self-amplifying messenger (SAM) RNA delivered with different formulations compared to controls |
-1.2 | | Spryd7 | 'infarct and border region of left ventricle 5 days post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
1.2 | | Spryd7 | "Evi1-GFP positive" vs "Evi1-GFP negative" | phenotype | Whole genome expression profiling of Evi1-GFP positive and negative murine hematopoietic stem cell sub-populations. |
1.1 | | Spryd7 | 'wild type; SARS MA15; 2 day' vs 'wild type; mock' | genotype, infect, time | Infection of wild type and CXCR3 knockout C57BL6/J mice with SARS MA15 |
1.1 | | Spryd7 | 'Porphyromonas gingivalis; hyperlipidemia' vs 'normal' | infect, phenotype | hyperlipidemia impaired innate response |
-1.1 | | Spryd7 | 'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.1 | | Spryd7 | '180 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
1.1 | | Spryd7 | '90 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
1.1 | | Spryd7 | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1.1 | | Spryd7 | 'MED23 knockout' vs 'wild type' | genotype | Mediator Med23-deficiency Enhances Neural Differentiation of Embryonic Stem Cells through Modulating BMP Signaling |
1.1 | | Spryd7 | 'DKO' vs 'wild type' | genotype | Transcription profiling by array of wild type and Hdac1 and 2 knockout lymphocytes |
1.1 | | Spryd7 | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.1 | | Spryd7 | 'SARS coronavirus MA15; 10^4 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.1 | | Spryd7 | 'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'BALB/cByJ' | infect, strain, time | Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans |
-1.1 | | Spryd7 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.1 | | Spryd7 | 'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
-1.1 | | Spryd7 | 'Tetrafluororethane; 50000 part per million; air' vs 'none; ; air' | compound, treatment | Transcription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals |
1 | | Spryd7 | 'Debaryomyces hansenii' at '12 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
1 | | Spryd7 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1 | | Spryd7 | 'Adjuvant System 03' at '8 hour' vs 'none' | compound, time | RNA-Seq of RAW 264.7 cells stimulated with the AS03 adjuvant after 4 and 8 hours |
1 | | Spryd7 | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
1 | | Spryd7 | 'Adjuvant System 03' at '4 hour' vs 'none' | compound, time | RNA-Seq of RAW 264.7 cells stimulated with the AS03 adjuvant after 4 and 8 hours |
1 | | Spryd7 | 'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day' | genotype, infect, time | Mouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice |
-1 | | Spryd7 | 'MEF2A knockout' vs 'wild type genotype' in 'Hoxb8-FL; none' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1 | | Spryd7 | 'Porphyromonas gingivalis; normal' vs 'normal' | infect, phenotype | hyperlipidemia impaired innate response |
-1 | | Spryd7 | 'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1 | | Spryd7 | 'SARS coronavirus MA15' vs 'none' at '2 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
-1 | | Spryd7 | 'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1 | | Spryd7 | 'cardiac-specific constitutive expression of an activated Akt (caAkt)' vs 'wild type genotype' | genotype | Transcription profiling by array of cardic ventricle tissues from mice with cardiac-specific constitutive expression of an activated Akt (caAkt) and wild-type controls to test whether Akt activation contributes to mitochondrial dysfunction in pathological cardiac hypertrophy |
1 | | Spryd7 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Spryd7 | 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day' | cell type, compound, time | Drug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs |
1 | | Spryd7 | 'Lsd1fl/fl Mx1Cre' vs 'Lsd1fl/fl' | genotype | Gene expression data of Lsd1fl/fl and Lsd1fl/fl Mx1Cre Gr1dim Mac1 granulocytic progenitor cells. |
1 | | Spryd7 | 'trichostatin A and LIF' at '12 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A |
-1 | | Spryd7 | 'Yin Yang 1 (YY1) knockout' vs 'wild type' | genotype | Expression data from mouse skeletal muscle |
-1 | | Spryd7 | 'renin-expression' vs 'control' | phenotype | Expression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein. |
-1 | | Spryd7 | 'infarct and border region of left ventricle 1 day post-myocardial infarction; MRL/MpJ' vs 'left ventricle at baseline (no myocardial infarction) in the same region as the infarct in post-myocardial infarction hearts; MRL/MpJ' | clinical information, strain | Expression data from C57BL/6J and MRL/MpJ hearts following acute myocardial infarction |
-1 | | Spryd7 | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
-1 | | Spryd7 | 'Taf10-/-' vs 'wild type' | genotype | Transcription profiling by array of liver from Taf10 knock out mice |
1 | | Spryd7 | 'lipid nanoparticle alone' vs 'phosphate buffered saline' | stimulus | Microarray analysis of mouse whole genome using self-amplifying messenger (SAM) RNA delivered with different formulations compared to controls |
-1 | | Spryd7 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
