ensmusg00000020037 (Rfx4)

mus musculus

regulatory factor X, 4 (influences HLA class II expression)

Filter your results

Mus musculus
Organism part
Showing 56 experiments:
Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumdorsal raphe nucleusheartleft cardiac atriummuscle (biceps femoris)preoptic areastriatumwhite adipose tissueblood plasmabronchuscorpora quadrigeminadiaphragmepididymisfloor platehypothalamusintestinemammary glandmedial prefrontal cortexolfactory bulboviductsaliva-secreting glandsmall intestinethymusuterus
T
49 FANTOM5 project - adult
T
49 FANTOM5 project - neonate
T
49 FANTOM5 project - juvenile
T
49 FANTOM5 project - embryonic day 18
T
49 FANTOM5 project - embryonic day 17
T
49 FANTOM5 project - embryonic day 16
T
49 FANTOM5 project - embryonic day 15
T
49 FANTOM5 project - embryonic day 14
T
9 in 3 strains - DBA/2J
T
9 in 3 strains - CD1
T
9
T
9 in 3 strains - C57BL/6
T
49 FANTOM5 project - embryonic day 12
T
14 - embryonic day 10.5
T
49 FANTOM5 project - embryonic day 13
T
Mammalian Kaessmann
T
6
T
Vertebrates
T
4
T
14 - embryonic day 9.5
T
14 - embryonic day 8.5
T
4 Bonthuis et al - CastEiJ
T
4 Bonthuis et al - (CastEiJ X …
T
4 Bonthuis et al - (C57BL/6J X …
T
Fat and muscle
T
Developing gut
T
49 FANTOM5 project - embryonic day 11
T
3 Soumillon et al
T
3
T
Sun et al., 2020 - Organism part
T
Gregg et al - CAST/EiJ
T
Gregg et al - C57BL/6J
T
Gregg et al - (CAST/EiJ X C57BL/6J)F1
T
Gregg et al - (C57BL/6J X CAST/EiJ)F1
T
4 Bonthuis et al - C57BL/6J
T
Mernberger et al 2019 - Organism Part
T
49 FANTOM5 project - pregnant adult day …
T
49 FANTOM5 project - pregnant adult day …
T
2
T
49 FANTOM5 project - pregnant adult day …
T
49 FANTOM5 project - pregnant adult day …
T
49 FANTOM5 project - lactating adult …
T
49 FANTOM5 project - embryonic day 17.5
T
49 FANTOM5 project - embryonic day 14.5
T
49 FANTOM5 project - embryo
T
4 Bonthuis et al - Idaho derived wild …
P
Organism part - Geiger et al
P
Organism part - Huttlin et al
P
Huttlin et al., 2010 - tissues - brain, …
P
Organism part - Malmstrom et al -
P
Linscheid et al., 2021 - tissue - heart …
P
Meierhofer et al., 2016 - organism part
P
Linscheid et al. 2019 - organism part
P
Deshmukh et al., 2015 - organism part
P
Zhao et al., 2019 - tissue - lens
P
Proteomics
T
Transcriptomics
High
Medium
Low
Below cutoff
No data available

Filter your results

Kingdom
Species
Experiment type
Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
6.3134 × 10-23-6.6
Rfx4'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.0452 × 10-179-6.1
Rfx4'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
3.3057 × 10-125
Rfx4'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.1801 × 10-654.9
Rfx4'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
1.9173 × 10-84.8
Rfx4'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
7.3872 × 10-7-4.6
Rfx4'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.2178 × 10-6-4.5
Rfx4'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.592 × 10-5-4.4
Rfx4'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
4.016 × 10-5-3.9
Rfx4'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.469 × 10-4-3
Rfx4'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
3.4851 × 10-42.9
Rfx4'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
6.9895 × 10-3-2.9
Rfx4'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.8769 × 10-6-2.7
Rfx4'Malathion; 14800 part per million; rodent chow' vs 'none; ; rodent chow'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
1.8612 × 10-32.7
Rfx4'cut nerve; 7 day' vs 'none'injury, protocol, timeChanges in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury
Adjusted p-valueLog2-fold change
2.2187 × 10-3-2.7
Rfx4'control; 36 hour after partial hepatechtomy' vs 'control; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
1.1388 × 10-32.5
Rfx4'diphtheria toxin; 30 nanogram per gram' vs 'none'stimulusRNA-seq of mouse brain tissue repopulating microglia in response to traumatic brain injury
Adjusted p-valueLog2-fold change
1.9112 × 10-32.5
Rfx4'fasted' vs 're-fed' in 'db/db; control miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.4756 × 10-52.3
Rfx4'fasted' vs 're-fed' in 'db/db; Gabpa miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.4526 × 10-5-2.3
Rfx4'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
4.4744 × 10-5-2.1
Rfx4'bisphenol AF; 10 micromolar' vs 'vehicle'compoundTranscriptomic analyses of 11.5 dpc female germ cell (mouse) exposed or not to Bisphenol A analogues (BPAF and BADGE)
Adjusted p-valueLog2-fold change
8.644 × 10-4-2.1
Rfx4'Plasmodium chabaudi infection' vs 'no infection' in 'vaccination'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
1.8355 × 10-3-2
Rfx4'conditional UPF2 knockout; before partial hepatechtomy' vs 'control; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
1.0854 × 10-2-1.9
Rfx4'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
5.2232 × 10-5-1.8
Rfx4'glioblastoma multiforme' vs 'normal'diseaseAnalysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus.
Adjusted p-valueLog2-fold change
6.261 × 10-3-1.8
Rfx4'dexamethasome' vs 'methyl beta-clodextrin' in 'Nr1d1 homozygous knockout; 1 milligram per kilogram; ZT6'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
3.0039 × 10-2-1.8
Rfx4'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
4.523 × 10-61.7
Rfx4'high fat' vs 'chow' in 'NZO/HILtJ'diet, strainTranscription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ
Adjusted p-valueLog2-fold change
7.6315 × 10-4-1.7
Rfx4'dexamethasome' vs 'methyl beta-clodextrin' in 'wild type genotype; 1 milligram per kilogram; ZT6'compound, genotype, timeRNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment
Adjusted p-valueLog2-fold change
2.381 × 10-31.7
Rfx4'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
1.9465 × 10-2-1.7
Rfx4'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector'genotypeRNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice
Adjusted p-valueLog2-fold change
9.1914 × 10-51.6
Rfx4'fasted' vs 're-fed' in 'wild type genotype; control miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
2.6521 × 10-3-1.5
Rfx4'fear conditioning' vs 'none'stimulusGene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage
Adjusted p-valueLog2-fold change
1.0121 × 10-21.4
Rfx4'high fat diet' vs 'regular chow diet' in 'liver-specific Pit1 knockout'diet, genotypeTranscription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet
Adjusted p-valueLog2-fold change
1.39 × 10-10-1.3
Rfx4'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.8876 × 10-61.3
Rfx4'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
5.6662 × 10-31.3
Rfx4'fasted' vs 're-fed' in 'wild type genotype; Gabpa miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
7.5058 × 10-3-1.3
Rfx4'Nrl-/-' vs 'wild type'genotypeNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Nrl-/- Retinal Transcriptomes
Adjusted p-valueLog2-fold change
2.2187 × 10-2-1.3
Rfx4'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.866 × 10-21.3
Rfx4'Drosha -/-' vs 'wild type genotype'genotypeRNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs
Adjusted p-valueLog2-fold change
5.9591 × 10-17-1.2
Rfx4'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
8.2359 × 10-15-1.2
Rfx4'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
4.5048 × 10-13-1.2
Rfx4'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
4.6035 × 10-8-1.2
Rfx4'valproic acid; 1000 micromolar' vs 'none' at '4 day'compound, timeTranscription profiling by array of mouse embryonic multipotent stem cells treated with valproic acid, cyproconazole and hexaconazole
Adjusted p-valueLog2-fold change
2.2757 × 10-7-1.2
Rfx4'Trim24,Trp53 double knockdown' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of mouse embryonic stem cells following Trim24 and/or p53 knockdown
Adjusted p-valueLog2-fold change
6.6077 × 10-71.2
Rfx4'Zbtb2 -/-' vs 'wild type genotype' in 'EpiLC' at '1 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
5.2409 × 10-61.2
Rfx4'365 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.2926 × 10-5-1.2
Rfx4'carbamazepine; 100 micromolar' vs 'none' at '4-day differentiated'compound, sampling time pointTranscriptional profiling by array of mouse embryonic stem cells treated with six different compounds
Adjusted p-valueLog2-fold change
2.3344 × 10-51.2
Rfx4'Mettl6 knockout clone G6' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
1.6419 × 10-21.2
Rfx4'transgenic' vs 'wild type' in '160 day; C57BL/6'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
3.2013 × 10-2-1.2
Rfx4'anterior rostral migratory stream' vs 'posterior rostral migratory stream'organism partTranscription profiling of mouse postnatal neuroblasts from posterior and anterior rostral migratory streams
Adjusted p-valueLog2-fold change
3.8713 × 10-12-1.1
Rfx4'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
7.0529 × 10-10-1.1
Rfx4'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
3.4289 × 10-61.1
Rfx4'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.5238 × 10-41.1
Rfx4'Nr1d1-/-' vs 'wild type genotype'genotypeTranscription profiling by array of liver tissues from wild type and Rev-erb{alpha} knockout (Nr1d1-/-) mice to study direct targets of Nr1d1 in rhythmic (circadian) transcription
Adjusted p-valueLog2-fold change
5.3144 × 10-3-1.1
Rfx4'NEMO-TNFR1 double knockout' vs 'wild type'genotypeTNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice.
Adjusted p-valueLog2-fold change
7.2619 × 10-31.1
Rfx4'Crx knockout' vs 'control' at '20 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
2.0152 × 10-51
Rfx4'Zbtb2 -/-' vs 'wild type genotype' in 'SerumLIF' at '1 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
1.8637 × 10-3-1
Rfx4'NEMO knockout' vs 'wild type'genotypeTNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice.
Adjusted p-valueLog2-fold change
2.6749 × 10-31
Rfx4'Reverbα -/-' vs 'wild type genotype'genotypeAntibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq
Adjusted p-valueLog2-fold change
2.9917 × 10-3-1
Rfx4'metaphase II oocyte' vs 'germinal vesicle oocyte'cell typeTranscription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming
Adjusted p-valueLog2-fold change
3.5564 × 10-31
Rfx4'tumor' vs 'normal' in 'liver'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
7.73 × 10-3-1
Rfx4'1,2-Dibromoethane; 62 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
1.0722 × 10-21
Rfx4'CAR deficient; ethanol and ellagic acid' vs 'CAR deficient; control'genotype, treatmentNuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages
Adjusted p-valueLog2-fold change
1.0779 × 10-21
Rfx4'intermittent fasting every 16 hours' vs 'ad libitum'dietGenome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver
Adjusted p-valueLog2-fold change
1.1145 × 10-2-1
Rfx4'AKR/J mice co-housed 1:1 with C57BL/6 mice' vs 'AKR/J mice in single housing'growth conditionGut microbiota and gallstone formation - cohousing study
Adjusted p-valueLog2-fold change
1.5604 × 10-2-1
Rfx4'db/db' vs 'wild type genotype' in 'control miRNA; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.7128 × 10-2-1
Rfx4'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'conditional UPF2 knockout; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy