ensmusg00000056158 (Car10)

mus musculus

carbonic anhydrase 10

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Mus musculus
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Showing 4 experiments:
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T
9 in 3 strains - CD1
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2
T
14 - embryonic day 10.5
T
Gregg et al - C57BL/6J
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Proteomics
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Transcriptomics
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-1
-8.9
1
5.1
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.1493 × 10-4-8.9
Car10'Cox6a2 knockout' vs 'wild type'phenotypeRNA-seq of PV+ interneurons in WT and Cox6a2-/- mice to unravel the molecular signaling that contributes to the increase in oxidative stress and metabolic dysregulation following Cox6a2 knockout.
Adjusted p-valueLog2-fold change
9.9954 × 10-7-5.2
Car10'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
4.0142 × 10-205.1
Car10'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
1.0635 × 10-6-4.8
Car10'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.4081 × 10-6-4.8
Car10'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.929 × 10-194.3
Car10'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.308 × 10-63.9
Car10"98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young"age, phenotypeRNAseq of whole ovarian follicles from young and old mice.
Adjusted p-valueLog2-fold change
3.7609 × 10-3-3.9
Car10'neural progenitor cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
5.1873 × 10-53.8
Car10'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 15.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
7.9388 × 10-3-3.8
Car10'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
1.3381 × 10-103.7
Car10'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.6747 × 10-173.2
Car10'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
2.9581 × 10-33.1
Car10'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
5.8811 × 10-3-3
Car10'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.814 × 10-3-2.6
Car10'subventicular zone of the lateral ventricle' vs 'cerebellum'organism partExpression data from adult Shh-responding astroglia cells in mice
Adjusted p-valueLog2-fold change
3.0155 × 10-452.5
Car10'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
3.2703 × 10-252.5
Car10'4-hydroxytamoxifen-mediated deletion of Prmt5' vs 'wild type' in 'mouse neural progenitor cell'cell type, phenotypeTranscription profiling by high throughput sequencing of murine neural stem/progenitor cells lacking PRMT5 over control
Adjusted p-valueLog2-fold change
2.2144 × 10-92.5
Car10'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.7829 × 10-72.5
Car10'10 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
1.8512 × 10-172.4
Car10'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
6.6533 × 10-3-2.4
Car10'hippocampus' vs 'cerebellum'organism partExpression data from adult Shh-responding astroglia cells in mice
Adjusted p-valueLog2-fold change
2.2077 × 10-22.4
Car10'AZD7507; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
7.6855 × 10-72.2
Car10'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.7855 × 10-42.2
Car10'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
8.9498 × 10-42.1
Car10'calorie restricted diet' vs 'normal diet' at '15 month'age, dietTranscription profiling by array of cochleae from mice fed a calorie-restricted diet
Adjusted p-valueLog2-fold change
1.9125 × 10-32.1
Car10'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
1.0624 × 10-2-2.1
Car10'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector'genotypeRNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice
Adjusted p-valueLog2-fold change
1.6681 × 10-22
Car10'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'wild type genotype'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
1.376 × 10-121.9
Car10'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
3.506 × 10-21.9
Car10'PDE10 inhibitor; PDE10A knockout; striatum' vs 'PDE10 inhibitor; wild type; striatum'compound, genotype, organism partMicroarray profiling of WT or PDE10A KO mice treated with vehicle or a PDE10 inhibitor
Adjusted p-valueLog2-fold change
7.0524 × 10-51.8
Car10'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+'compound, genotypePolycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos)
Adjusted p-valueLog2-fold change
2.7829 × 10-2-1.8
Car10'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar'compound, genotypeOverexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment
Adjusted p-valueLog2-fold change
4.8427 × 10-21.8
Car10'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 18.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
4.4525 × 10-53-1.7
Car10'beta cell specific Pax6 knockout' vs 'wild type'phenotypeRNA-Seq of pancreatic islets from beta cell-specific Pax6 knockout mice
Adjusted p-valueLog2-fold change
1.4471 × 10-3-1.6
Car10'metaphase II oocyte' vs 'germinal vesicle oocyte'cell typeTranscription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming
Adjusted p-valueLog2-fold change
1.8377 × 10-41.5
Car10'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
4.8173 × 10-41.5
Car10'Crx knockout' vs 'control' at '6 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
2.0661 × 10-21.5
Car10'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
3.8851 × 10-21.5
Car10'Insm1-expressing endocrine progenitor cell' vs 'Insm1-lacking endocrine progenitor cell' in 'embryonic day 15.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
1.782 × 10-4-1.4
Car10'permanent neonatal diabetes mellitus' vs 'normal'diseaseMicroarray comparing gene expression changes between control, normoglycaemic mice, and mice expressing the human neonatal diabetes mutation Kir6.2-V59M in pancreatic beta-cells left diabetic for 2 weeks
Adjusted p-valueLog2-fold change
7.8807 × 10-3-1.4
Car10'Hnf4a-pKO;Hnf1aHET double mutant' vs 'wild type genotype'genotypeTranscription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice
Adjusted p-valueLog2-fold change
7.584 × 10-5-1.3
Car10'glioblastoma multiforme' vs 'normal'diseaseAnalysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus.
Adjusted p-valueLog2-fold change
7.8318 × 10-3-1.3
Car10'dorsolateral nucleus motor neuron' vs 'lumbar motor neurons'cell typeComparison of gene expression in motor pools with differential vulnerability in ALS
Adjusted p-valueLog2-fold change
1.5602 × 10-2-1.3
Car10'proliferating progenitor' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
3.7423 × 10-2-1.3
Car10'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1'cell type, growth condition, phenotypeTranscription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture
Adjusted p-valueLog2-fold change
4.4443 × 10-5-1.2
Car10'Chikungunya virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
1.279 × 10-2-1.2
Car10'pancreas-specific Hnf4alpha knockout' vs 'wild type genotype'genotypeTranscription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice
Adjusted p-valueLog2-fold change
1.6958 × 10-21.2
Car10'Crx knockout' vs 'control' at '20 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
1.0837 × 10-21.1
Car10'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL'genotype, sampling time point, strainTranscription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
Adjusted p-valueLog2-fold change
3.1264 × 10-2-1.1
Car10'120 day; Sod1 G93A' vs '120 day; wild type genotype'age, genotypeTranscription profiling of astrocytes from the symptomatic and late-stage time points of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis (ALS)
Adjusted p-valueLog2-fold change
1.4149 × 10-31
Car10'7 day' vs '0 day'ageTranscriptional profiling by array of mouse cerebellar cortex during postnatal development
Adjusted p-valueLog2-fold change
2.1173 × 10-2-1
Car10'Hnf1a knock out' vs 'wild type'genotypeTranscription profiling of pancreatic islets from Hnf1a-deficient and wild type mice
Synonym
CA-RP X, 2700029L05Rik
Ortholog
ca10a (Danio rerio), cah-5 (Caenorhabditis elegans), cah-6 (Caenorhabditis elegans), CA10 (Bos taurus), ENSCSAVG00000003049 (Ciona savignyi), ENSTNIG00000014012 (Bos taurus), ENSACAG00000017362 (Anolis carolinensis), CARPB (Drosophila melanogaster), CA10 (Anas platyrhynchos), ENSTNIG00000005272 (Bos taurus), CA10 (Equus caballus), ENSMODG00000033172 (Monodelphis domestica), CAH4 (Drosophila melanogaster), ENSTNIG00000006082 (Bos taurus), CA10 (Macaca mulatta), CAH15 (Drosophila melanogaster), CA10 (Pongo abelii), cah-1 (Caenorhabditis elegans), ca10 (Xenopus tropicalis), CA10 (Sus scrofa), ENSOARG00020021387 (Salmo salar), CA10 (Gallus gallus), ca10b (Danio rerio), CA10 (Pan troglodytes), Car10 (Rattus norvegicus), CA10 (Oryctolagus cuniculus), CAH13 (Drosophila melanogaster), CAH14 (Drosophila melanogaster), CA10 (Homo sapiens), CA10 (Gorilla gorilla), ENSTNIG00000019532 (Bos taurus), CA10 (Ornithorhynchus anatinus), CAH7 (Drosophila melanogaster), CA10 (Chlorocebus sabaeus), CA10 (Papio anubis), CA10 (Dasypus novemcinctus), ENSCING00000000176 (Salmo salar)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
5375571, 17255097, 5503610, 1431288_at, 4308047, ILMN_1257999, A_55_P1952091, 5602938, ILMN_1221323, 5419070, ILMN_1217693, 4728751, 5467470, 4915295, 5064104, 4364439, 4963827, 1424547_at, A_55_P1952101, ILMN_2594325, 5532198, 5579011, A_52_P256997, 4455539, A_51_P268863, 5582818, ILMN_1217638, 4934198, 5519423, 5018777, ILMN_1254267, 4678192, 5468821, 4327701, A_55_P2397904, 5001466, 4618720, 4790531, 167747_f_at, A_55_P1952086, 4983198, 4957441, 5522785, 5577451, 5001707, 166211_at, 4451110, 4886406, 4804782, 10380303