-6.1 | | Bmper | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
-5.6 | | Bmper | 'Sox17.Epi' vs 'Sox17.Endo' | genotype | Transcription profiling by high throughput sequencing of Sox17.Epi and Endo cells from mouse embryos |
5.3 | | Bmper | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
5.2 | | Bmper | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
-5 | | Bmper | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
4.4 | | Bmper | 'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
4.4 | | Bmper | '4 hours after hCG treatment' vs 'control' in 'wild type' | genotype, treatment | The ISWI ATPase Snf2L is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells |
4.3 | | Bmper | '3 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
4 | | Bmper | 'neuronal stem cell; positive staining for GFP and prominin' vs 'astrocyte; positive staining for GFP' | cell type, phenotype | Transcription profiling by array of adult neural stem cells (hGFAP-GFP+/prominin1+ cells) compared to parenchymal astrocytes that are not neurogenic (hGFAP-GFP+ cells from the diencephalon) |
4 | | Bmper | '4 hours after hCG treatment' vs 'control' in 'Snfl2 Ex6DEL' | genotype, treatment | The ISWI ATPase Snf2L is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells |
-3.8 | | Bmper | '0.45 micromolar; 5-fluourouracil' vs 'none' at '24 hour' | compound, time | Transcription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid |
3.6 | | Bmper | 'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol' | genotype, treatment | Transcription profiling by high throughput sequencing of uterine-specific Tsc2-null mice |
3.5 | | Bmper | '4 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
3.4 | | Bmper | 'interleukin-3 and interleukin-33' vs 'interleukin-3' | growth condition | Stem cell factor programs the mast cell activation phenotype |
3.3 | | Bmper | 'control mice [Gp130f/f]; cecal ligation and puncture' vs 'control mice [Gp130f/f]; control' | genotype, treatment | Hepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function |
-3.2 | | Bmper | 'mutant MyoD expression' at '24 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
-3.2 | | Bmper | '5,9-endoperoxy-cholest-7-en-3β,6α-diol' vs 'vehicle (cyclodextrin)' | compound, time | Array results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol |
3.2 | | Bmper | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-3.1 | | Bmper | 'neuron' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
3.1 | | Bmper | '10 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
3.1 | | Bmper | 'db/db' vs 'wild type genotype' in 'Gabpa miRNA; fasted' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
3.1 | | Bmper | Synacthen vs sodium chloride control | compound | Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses. |
-3 | | Bmper | 'pkd1 knockout' vs 'wild type' in 'absence of fluid flow' | genotype, stimulus | Transcription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow |
3 | | Bmper | 'db/db' vs 'wild type genotype' in 'control miRNA; re-fed' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
-3 | | Bmper | '70 week' vs '6 week' in 'none; none; | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
-3 | | Bmper | 'Macrophage of F4/80+, CD11b+, CD11c-; obese leptin-deficient' vs 'Macrophage of F4/80+, CD11b+, CD11c-; control' | cell type, genotype | Expression data from mouse adipose tissue macrophage |
2.9 | | Bmper | '6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
2.8 | | Bmper | '21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
2.8 | | Bmper | 'ductus arteriosis' vs 'aorta' | organism part | Gene Profiling in Mouse Fetal Ductus Arteriosus |
2.8 | | Bmper | 'ulcer' vs 'distant normal tissue' in 'wild type genotype' | genotype, sampling site, time | Intestinal ulcers from biopsy-wounded wild-type and Bmp4-overexpressing mice |
2.7 | | Bmper | 'Lmna G609G/G609G knock in' vs 'wild type' | genotype | Transcription profiling by array of mouse liver with Lmna Gly609Gly knock in |
-2.7 | | Bmper | 'MED23 knockout' vs 'wild type' | genotype | Mediator Med23-deficiency Enhances Neural Differentiation of Embryonic Stem Cells through Modulating BMP Signaling |
2.7 | | Bmper | 'Gata6 knockout' vs 'wild type' | phenotype | Global gene expression in the adult Gata6 null mouse pancreas |
-2.7 | | Bmper | 'FXR KO' vs 'wild type genotype' | genotype | Transcription profiling by array of liver samples from FXR+/+ (wt) and liver-specific FXR KO (lKO) mice |
2.6 | | Bmper | 'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype' | genotype, treatment | Gene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice. |
2.6 | | Bmper | 'db/db' vs 'wild type genotype' in 'Gabpa miRNA; re-fed' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
2.5 | | Bmper | 'liver-specific Cnot1 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
-2.5 | | Bmper | 'CD2314' vs 'none' at '6 day' | age, compound | Transcription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors |
2.4 | | Bmper | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
2.4 | | Bmper | 'Mkl1-RFP with a mutated SRF-interaction site' vs 'full length Mkl1-RFP' | genotype | Transcription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1) |
-2.4 | | Bmper | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-2.4 | | Bmper | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
2.4 | | Bmper | 'db/db' vs 'wild type genotype' in 'control miRNA; fasted' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
-2.4 | | Bmper | 'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar' | compound, genotype | Overexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment |
-2.3 | | Bmper | 'mutant MyoD expression' at '12 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
2.3 | | Bmper | '5 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-2.3 | | Bmper | 'V6.5; embryonic stem cell’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
2.3 | | Bmper | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.3 | | Bmper | '19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
-2.2 | | Bmper | 'induced neural stem cell' vs 'mouse embryonic fibroblast cell' | cell type | Gene expression profile of mouse induced neural stem cells |
-2.2 | | Bmper | 'spontaneous lung tumor' vs 'normal' | disease state, disease | Transcription profiling by array of spontaneous lung tumors in mice to compare to human non-small cell lung cancer |
2.2 | | Bmper | 'inh-alpha/Tag transgenic' vs 'wild type' in 'none' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
-2.2 | | Bmper | 'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week' | age, genotype | Prevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA |
2.2 | | Bmper | 'control; 36 hour after partial hepatechtomy' vs 'control; before partial hepatechtomy' | genotype, sampling time | Transcription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy |
2.2 | | Bmper | 'ulcer' vs 'distant normal tissue' in 'Bmp4 overexpression' | genotype, sampling site, time | Intestinal ulcers from biopsy-wounded wild-type and Bmp4-overexpressing mice |
-2.2 | | Bmper | 'CD2314 and BIO' vs 'none' at '6 day' | age, compound | Transcription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors |
2.1 | | Bmper | 'chronic pancreatitis' vs 'control' | disease | Pancreatic gene expression associated with cerulein induced chronic pancreatitis in mice |
-2.1 | | Bmper | '6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
2.1 | | Bmper | 'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
2.1 | | Bmper | 'Foxd3 knockout' vs 'control' | phenotype | Expression data from embryonic stem cells differentiation |
-2.1 | | Bmper | 'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
2.1 | | Bmper | 'liver-specific Gp130 knockout mice [Gp130delta(hepa)]; cecal ligation and puncture' vs 'liver-specific Gp130 knockout mice [Gp130delta(hepa)]; control' | genotype, treatment | Hepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function |
-2.1 | | Bmper | '129S1 allele at SNP rs50454566' vs 'wild type genotype' | genotype | RNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene |
2.1 | | Bmper | 'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'wild type' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
2 | | Bmper | 'InsR, Igf1R double knockout' vs 'wild type' in 'postnatal day 5' | developmental stage, genotype | Transcriptional profiling by array of mouse wild-type and Insulin receptor (InsR)/Igf1 receptor (Igf1R) double knockout mutant Sertoli cells from testis at embryonic day E17.5 and Postnatal day 5 |
2 | | Bmper | '6 day' vs '0 day' | time | Transcription profiling by array of mouse colon tissues under dextran sodium sulphate induction for 2, 4 and 6 days against uninduced controls at day 0 |
-2 | | Bmper | 'pkd1 knockout' vs 'wild type' in 'presence of fluid flow' | genotype, stimulus | Transcription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow |
2 | | Bmper | 'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1.9 | | Bmper | '6 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
1.9 | | Bmper | 'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype' | genotype, treatment | Gene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice. |
1.9 | | Bmper | '21 percent oxygen, 37 degree Celsius, no serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
-1.9 | | Bmper | 'total RNA; HRasV12 and c-Myc overexpression and Eif4e wild type' vs 'total RNA; wild type' | fraction, genotype | Redefining the role of eIF4E dose in development, cancer, and protein synthesis |
-1.9 | | Bmper | '120 day; Sod1 G93A' vs '120 day; wild type genotype' | age, genotype | Transcription profiling of astrocytes from the symptomatic and late-stage time points of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis (ALS) |
1.9 | | Bmper | 'dextran sodium sulphate induced colitis' at '7 day' vs 'normal' at '0 day' | disease, time | Transcription profiling by array of Mus musculus colonic mucosa after treatment with dextran sodium sulphate (DSS) for 2 or 7 days which induces experimental colitis |
1.9 | | Bmper | 'p53 null mutant; plagL2 vector' vs 'p53 null mutant; empty vector' | genotype | Transcription profiling by array of mouse primary neural stem cells mutant for p53 after infection with retrovirus expressing PLAGL2 |
1.8 | | Bmper | '10 month' vs '2 month' | age | RNA-seq of adipocyte progenitor cells derived from old and young mice to investigate the molecular signature of aging |
1.8 | | Bmper | 'CD36 knockout' vs 'wild type genotype' in 'oxidized low density lipoprotein; 25 microgram per milliliter' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
-1.8 | | Bmper | 'MEF; transduced with MyoD lentivirus' vs 'MEF; control' | cell line, treatment | Genetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling] |
1.8 | | Bmper | 'liver-specific Cnot3 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
1.8 | | Bmper | 'Mettl6 knockout clone G6' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
1.8 | | Bmper | 'dextran sodium sulfate' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq analysis of colonic intestinal epithelial cells (IECs) isolated from naive wild-type C57BL/6 mice, DSS-treated wild-type C57BL/6 mice, Il10-/- C57BL/6 mice and Il10-/- C57BL/6 mice with IEC-specific Rabgef1 deletion |
-1.8 | | Bmper | 'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
1.8 | | Bmper | 'H9; undifferentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; undifferentiated embryonic stem cell' at '0 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
1.8 | | Bmper | 'S6K1 knockout' vs 'wild type' in 'liver' | genotype, organism part | Transcription profiling of mouse long-lived S6K1 -/- strain females compared to wild types |
-1.8 | | Bmper | 'BIO' vs 'none' at '6 day' | age, compound | Transcription profiling of mouse embryonic stem cell line CGR8 during differentiation to mesenchymal stem cells and then adipocyte precursors |
1.8 | | Bmper | 'liver specific SMARCB1 knockout' vs 'wild type' | phenotype | TP53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors |
1.7 | | Bmper | 'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.7 | | Bmper | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
1.7 | | Bmper | 'follicle stimulating hormone and epidermal growth factor' vs '293H control medium' | growth condition | Transcription profiling by array of mouse cumulus cells after culture with growth differentiation factor 9 or follicle stimulating hormone and epidermal growth factor |
1.7 | | Bmper | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
1.7 | | Bmper | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.7 | | Bmper | 'total RNA; HRasV12 and c-Myc overexpression and Eif4e heterozygous knockout' vs 'total RNA; wild type' | fraction, genotype | Redefining the role of eIF4E dose in development, cancer, and protein synthesis |
-1.7 | | Bmper | 'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
1.7 | | Bmper | 'high fat diet' vs 'regular chow diet' in 'wild type genotype' | diet, genotype | Transcription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet |
1.7 | | Bmper | 'TGFβ, 5 nanogram per milliliter' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-1.6 | | Bmper | 'oral hard palate epithelium' vs 'tail skin epithelium' | organism part | Transcriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression |
1.6 | | Bmper | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-1.6 | | Bmper | 'Rb^{lox/lox}; p130^{lox/lox}; p107+/-' vs 'wild type' | genotype | Transcription profiling by array of livers from the mouse model of human hepatocellular carcinoma |
1.5 | | Bmper | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-1.5 | | Bmper | 'MG132; 1 micromolar' vs 'DMSO' in 'CHOP-/-' | compound, genotype | Microarray to find CHOP dependent genes in response to proteasome inhibition |
-1.5 | | Bmper | '12 nanomolar; retinoic acid' vs 'none' at '24 hour' | compound, time | Transcription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid |
1.5 | | Bmper | 'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1.5 | | Bmper | 'cholesterol' vs 'vehicle (cyclodextrin)' | compound, time | Array results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol |
-1.5 | | Bmper | 'Sall4 homozygous knockout' vs 'wild type genotype' | genotype | RNA-Seq of Sall4 mutants in mouse embryonic stem cells |
1.5 | | Bmper | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
1.5 | | Bmper | 'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
1.5 | | Bmper | '6 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-1.5 | | Bmper | 'R1_Pax4+' at '0 day' vs 'wild type' at '0 day' | phenotype, time | Transcription profiling of mouse wild type R1 and cells expressing Pax4 following induction of pacreatic differentitation |
-1.5 | | Bmper | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
1.5 | | Bmper | '7 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
1.5 | | Bmper | 'tumor' vs 'normal' in 'liver' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
1.5 | | Bmper | 'Mettl6 knockout clone D1' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
-1.5 | | Bmper | 'TLR4 mutant' vs 'wild type genotype' in 'CCl4 and diethylnitrosamine' | genotype, treatment | Gene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice. |
1.5 | | Bmper | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.5 | | Bmper | '30 month' vs '5 month' in 'male' | age, block, sex | Expression data from tail skin in young (5 months) and old (30 months) CB6F1 mice |
1.4 | | Bmper | 'CD36 knockout' vs 'wild type genotype' in 'none' | compound, genotype | Quantitative analysis of wild type and cd36-/- murine peritoneal macrophage transcriptomes |
1.4 | | Bmper | 'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.4 | | Bmper | 'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.4 | | Bmper | 'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.4 | | Bmper | 'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1.4 | | Bmper | 'Alk5 fl/fl; Wnt1-Cre' vs 'control' | genotype | Gene expression profiling of the tongue bud from Alk5 mutant mouse models |
1.4 | | Bmper | 'mutant MyoD expression' at '6 hour' vs 'control' at '6 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
1.4 | | Bmper | 'TGF-beta; 15 nanogram per milliliter' vs 'control' | compound | TGF beta Dosage Experiment |
-1.4 | | Bmper | 'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'co-culture' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
1.4 | | Bmper | 'IL-6' at '4 hour' vs 'none' at '0 hour' | compound, time | Time-series of IL-6 stimulated primary mouse hepatocytes |
-1.4 | | Bmper | 'carcinoma' vs 'normal' | disease | Gene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse |
1.4 | | Bmper | 'tumor' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
1.4 | | Bmper | 'Stella maternal / zygotic knockout' vs 'wild type genotype' in '1-cell embryo' | developmental stage, genotype | Transcription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development |
1.4 | | Bmper | 'BMP4 40 nanograms per milliliter' vs 'none' | compound, dose | TGF-beta and BMP mediated gene expression in cultured sclerotome. |
-1.4 | | Bmper | 'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control' | phenotype | Temporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice |
1.4 | | Bmper | 'SARS coronavirus MA15 E protein mutant Δ3' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1.4 | | Bmper | '4 joule per square meter ultraviolet light' vs 'none' in 'wild type' | genotype, irradiate | Transcription profiling by array of mouse wild type and DNA-repair-deficient primary dermal fibroblasts after treatment with ultraviolet radiation |
-1.4 | | Bmper | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
1.3 | | Bmper | 'proliferating progenitor' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
1.3 | | Bmper | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1.3 | | Bmper | 'Pbx1 -/-; Pbx2 -/-' vs 'wild type genotype' at '12 hour' | genotype, time | RNA-seq of wild-type, Pbx1/Pbx2 double-knockout and pMsgn1-mut EpiSCs differentiated in vitro to pre-somitic mesoderm in the first 24 hours of differentiation. |
-1.3 | | Bmper | 'Reverbα-/- global knockout' vs 'Reverbα wild type' in 'not applicable; 13 week' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
1.3 | | Bmper | '168 hour' vs '0 hour' on 'Affymetrix MOE430B Array' | time | Transcription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
1.3 | | Bmper | 'Crx knockout' vs 'control' at '6 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
-1.3 | | Bmper | 'FusΔNLS/+' vs 'wild type genotype' at '12 hour' | genotype, time | Mutant FUS triggers age-dependent synaptic impairment in presymptomatic ALS-FUS mice (RNA-seq part2) |
1.3 | | Bmper | 'Gata3 knock out' vs 'wild type' | genotype | Transcription profiling by array of Gata3 knock-out mice |
-1.3 | | Bmper | 'left ventricle' vs 'right ventricle' in 'embryonic day 12.5' | developmental stage, organism part | Transcriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome |
1.3 | | Bmper | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.3 | | Bmper | 'Dicer knock out' vs 'wild type' | genotype | Transcription profiling by array of mouse Dicer-deficient ooctyes |
1.3 | | Bmper | 'fasted' vs 're-fed' in 'wild type genotype; control miRNA' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
1.3 | | Bmper | 'CD47 knockdown; endothelial’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
1.3 | | Bmper | 'high fat diet' vs 'regular chow diet' in 'liver-specific Pit1 knockout' | diet, genotype | Transcription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet |
1.2 | | Bmper | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1.2 | | Bmper | 'Ink4a/Arf-/-; EGFRvIII' vs 'wild type genotype' in 'separate' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
1.2 | | Bmper | 'Mkl1-RFP with a deletion of the SAP domain' vs 'full length Mkl1-RFP' | genotype | Transcription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1) |
-1.2 | | Bmper | 'mutant MyoD expression' at '6 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
1.2 | | Bmper | 'IL-6' at '2 hour' vs 'none' at '0 hour' | compound, time | Time-series of IL-6 stimulated primary mouse hepatocytes |
-1.2 | | Bmper | 'left ventricle' vs 'right ventricle' in 'embryonic day 9.5' | developmental stage, organism part | Transcriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome |
1.2 | | Bmper | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.2 | | Bmper | 'tape stripping' vs 'control' | treatment | Transcription profiling by array of mouse dorsal skin after tape stripping and treatment with winged bean extract. |
1.2 | | Bmper | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '7 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1.2 | | Bmper | 'Setd5 homozygous (null) knockout' vs 'Setd5 heterozygous knockout' | genotype | Transcriptional profiling of Setd5 heterozygous and knockout mouse embryonic stem cells |
1.2 | | Bmper | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1.1 | | Bmper | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.1 | | Bmper | 'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.1 | | Bmper | '3 day; myogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn378' | cell line, growth condition, time | Effect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation |
-1.1 | | Bmper | '10 day' vs '0 day' | age | Transcriptional profiling by array of mouse cerebellar cortex during postnatal development |
1.1 | | Bmper | 'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1.1 | | Bmper | 'GW501516' at '48 hour' vs 'none' | compound, time | PPARd target genes in MEFs |
1.1 | | Bmper | '336 hour' vs '0 hour' on 'Affymetrix MOE430B Array' | time | Transcription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
1.1 | | Bmper | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
-1.1 | | Bmper | 'shRNA mediated Brd4 knockdown' vs 'control shRNA' | treatment | Expression Data For BRD4 Inhibition |
1.1 | | Bmper | 'methionine- and choline-deficient, high fat diet' vs 'normal' | diet | Expression data from mouse liver treated with metformin |
1.1 | | Bmper | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
1.1 | | Bmper | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
1.1 | | Bmper | 'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte' | cell type, compound, genotype | Transcription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin |
1.1 | | Bmper | 'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only' | infect, treatment | Protective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase |
1.1 | | Bmper | 'Crx knockout' vs 'control' at '20 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
-1.1 | | Bmper | '2% curcumin' vs 'control' in 'trinitrobenzene sulfonic acid-induced experimental colitis' on 'Affymetrix MOE430B' | diet, disease | Transcription profiling by array of colon tissues from mice with or without trinitrobenzene-sulfonic acid induced colitis fed on standard diet or on anti-inflammatory compound Curcumin |
1.1 | | Bmper | '14M1.4; Leishmania donovani infected' at '48 hour' vs '14M1.4; normal' at '48 hour' | cell line, infect, time | Transcription profiling of 3 mouse cell lines infected with Leishmania |
1.1 | | Bmper | 'dextran sodium sulphate induced colitis' vs 'normal' in 'water' | compound, disease | Transcription profiling by array of murine colon tissue after exposure to 4% dextran sodium sulphate (DSS) for 6 days followed by 4 days of water or 1% L-arginine to study the effect of L-arginine on DSS-induced colitis |
-1 | | Bmper | 'MG132; 1 micromolar' vs 'DMSO' in 'wild type' | compound, genotype | Microarray to find CHOP dependent genes in response to proteasome inhibition |
1 | | Bmper | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'WSB/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1 | | Bmper | 'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1 | | Bmper | '7 day' vs '0 day' | age | Transcriptional profiling by array of mouse cerebellar cortex during postnatal development |
1 | | Bmper | 'homozygous Cav1.1 mutant' vs 'Cav1.1 wild type' in 'embryonic day 18.5' | developmental stage, genotype | Microarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels |
-1 | | Bmper | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1 | | Bmper | 'transgenic hepatic growth hormone' vs 'wild type genotype' in '12 week' | age, genotype | Hepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice |
1 | | Bmper | 'high fat' vs 'chow' in 'C57BL/6J' | diet, strain | Transcription profiling by high throughput sequencing of a Diversity Outbred mice population and the eight founder strains: A/J, 129S1/SvImJ, C57BL/6J, NOD/ShiLtJ, NZO/HlLtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ |
-1 | | Bmper | 'HDM allergen; IL-13 knockout' vs 'PBS control; IL-13 knockout' on 'Affymetrix MOE430B Array' | compound, genotype | Transcription profiling of wild type and IL13 knock out mice treated with allergen vs. control to investigate the IL13 role in allergic asthma |
1 | | Bmper | 'oxygen/glucose-deprivation followed by restoration of oxygen/glucose' vs 'none' in 'wild type genotype; undifferentiated' | genotype, growth condition, stimulus | SUMOylation promotes survival and integration of neural stem cell grafts in stroke |
1 | | Bmper | 'PAI1 knockout; SARS MA15; 4 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1 | | Bmper | 'trinitrobenzene sulfonic acid-induced experimental colitis' vs 'normal' in 'control' on 'Affymetrix MOE430B' | diet, disease | Transcription profiling by array of colon tissues from mice with or without trinitrobenzene-sulfonic acid induced colitis fed on standard diet or on anti-inflammatory compound Curcumin |
1 | | Bmper | 'Fxr -/-' vs 'wild type' | diet, genotype, pregnancy | Transcription profiling by array of mouse liver from control, pregnant, cholate fed mice and Frx null mice |
1 | | Bmper | 'CAR deficient; ethanol and trans-resveratrol' vs 'wild type; ethanol and trans-resveratrol' | genotype, treatment | Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages |
-1 | | Bmper | 'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '12 month' | age, genotype | ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression] |
1 | | Bmper | 'S-(1,2-dichlorovinyl)-L-cysteine; 15 milligram per kilogram; renal injury; 1 week' vs 'none; normal' | compound, disease, time | Expression profiling experiment on Pkd1-mutant mice and mice induced with nephrotoxin DCVC |
1 | | Bmper | 'PAI1 knockout; SARS MA15; 7 day' vs 'PAI1 knockout; mock' | genotype, infect, time | SARS infection of C57BL6, TIMP1 and Serpine1 knock-out mice |
1 | | Bmper | 'Insig1 -/-' vs 'wild type genotype' in 'none; standard diet; acute liver damage' | compound, diet, disease, genotype | INSIG1 in NASH pathophysiology and in the hepatic wound-healing response |
1 | | Bmper | 'SARS coronavirus MA15' vs 'mock' | infect | Host responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains |
-1 | | Bmper | 'colitis' vs 'normal' in 'wild type' | compound, disease, genotype | Transcription profiling by array of wild-type or Thrombospondin 1 (TSP-1) null mouse dextran sulphate sodium (DSS)-induced colitis treated with various forms of TSP-1, a protein with regulatory functions in inflammation and cancer |
1 | | Bmper | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
