5.6 | | Tlcd4 | 'erythroblast' vs 'hematopoietic stem cell' | cell type | Transcription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells |
-5.5 | | Tlcd4 | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
-5.3 | | Tlcd4 | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
5.2 | | Tlcd4 | 'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-5.2 | | Tlcd4 | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
-4.9 | | Tlcd4 | 'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week' | age, genotype | Prevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA |
4.8 | | Tlcd4 | 'Cbs knockout' vs 'wild type' | genotype | Gene expression profile of CD4-positive T cells from mouse Cbs knockout |
4.5 | | Tlcd4 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-4.5 | | Tlcd4 | 'Lkb1 -/- Pten-/-' vs 'wild type' | genotype | Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells |
-4.5 | | Tlcd4 | 'synovial sarcoma' vs 'normal' | disease | Transcription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice |
-4.4 | | Tlcd4 | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
4.3 | | Tlcd4 | 'wild type; mature luminal' vs 'wild type; MaSC/basal' | cell type, genotype | Expression data from sorted control and Pygo2-null mouse mammary stem/basal cells |
4.3 | | Tlcd4 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-4.2 | | Tlcd4 | 'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
4.2 | | Tlcd4 | 'Er1F/-' vs 'wild type genotype' | genotype | RNA-Seq profiling of ERCC1-XPF DNA repair defect (Er1F/-) versus wild type (Er1F/+) macrophages |
-4.1 | | Tlcd4 | 'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
4 | | Tlcd4 | '130 week' vs '13 week' in 'spleen' | age, organism part | Transcription profiling by array of liver, lung, spleen and kidney from young and old mice. |
-3.9 | | Tlcd4 | 'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
3.9 | | Tlcd4 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
3.8 | | Tlcd4 | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
-3.8 | | Tlcd4 | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
3.8 | | Tlcd4 | 'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens |
-3.8 | | Tlcd4 | 'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-3.8 | | Tlcd4 | 'oral hard palate epithelium' vs 'tail skin epithelium' | organism part | Transcriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression |
-3.6 | | Tlcd4 | 'renin-expression' vs 'control' | phenotype | Expression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein. |
-3.5 | | Tlcd4 | 'PGC-1 beta knock in' vs 'wild type' | genotype | Transcription profiling by array of skeletal muscle from PGC-1 beta transgenic mice |
-3.4 | | Tlcd4 | 'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-3.3 | | Tlcd4 | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
3.2 | | Tlcd4 | 'normobaric hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo. |
-3.2 | | Tlcd4 | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-3.2 | | Tlcd4 | '5 day; Ad-VEGF-A164' vs '0 day; control' | time, treatment | Transcription profiling by array of stromal-based signatures for the classification of gastric cance |
3.1 | | Tlcd4 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
3.1 | | Tlcd4 | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-3 | | Tlcd4 | 'cut nerve; 7 day' vs 'none' | injury, protocol, time | Changes in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury |
-3 | | Tlcd4 | 'Tbx5;Nkx2-5 knockout' vs 'wild type' | genotype | Transcription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse |
3 | | Tlcd4 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-2.9 | | Tlcd4 | 'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-2.7 | | Tlcd4 | 'clear cell sarcoma; Rosa26CreER' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-2.7 | | Tlcd4 | 'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
2.7 | | Tlcd4 | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.6 | | Tlcd4 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.5 | | Tlcd4 | 'Insm1-expressing endocrine progenitor cell' vs 'Insm1-lacking endocrine progenitor cell' in 'embryonic day 15.5' | cell type, developmental stage | Transcriptional regulation of endocrine cell differentiation by Insm1 |
2.5 | | Tlcd4 | '16 day' vs '0 day' | age | Gene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26) |
-2.5 | | Tlcd4 | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
-2.5 | | Tlcd4 | 'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
2.5 | | Tlcd4 | '14 days P. chabaudi infected' vs 'uninfected' in 'intact male' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-2.5 | | Tlcd4 | 'collagen sandwich' at '1 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
2.5 | | Tlcd4 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-2.5 | | Tlcd4 | 'Mst1/2 knockout' vs 'control' | genotype | Microarray of Mst1/2 deleted epithelial cells from E18.5 mouse lungs |
2.5 | | Tlcd4 | 'inducible deletion of Mll' vs 'control' | treatment | MLL regulated genes in LSK/CD48- hematopoietic stem cells |
2.5 | | Tlcd4 | 'Nix knock out' vs 'wild type' | genotype | Transcription profiling by array of spleens from mice with Nix knocked out. |
-2.5 | | Tlcd4 | 'tumor' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-2.5 | | Tlcd4 | 'Tet2 knockout' vs 'wild type' in 'hematopoietic stem cell' | cell type, genotype | Transcription profiling by high throughput sequencing of bone marrow stem and progenitor cells from Tet2 depleted mice |
-2.5 | | Tlcd4 | 'Nkx2-5 knockout' vs 'wild type' | genotype | Transcription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse |
2.4 | | Tlcd4 | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
2.4 | | Tlcd4 | '14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized male' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-2.4 | | Tlcd4 | 'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
2.4 | | Tlcd4 | '14 days P. chabaudi infected' vs 'uninfected' in 'intact female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
2.4 | | Tlcd4 | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'inguinal fat pad' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
-2.3 | | Tlcd4 | '21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
-2.3 | | Tlcd4 | 'glioblastoma multiforme' vs 'normal' | disease | Analysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus. |
-2.3 | | Tlcd4 | 'inh-alpha/Tag transgenic' vs 'wild type' in 'none' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
2.3 | | Tlcd4 | '45 percent caloric restriction' vs 'control' | diet | Gene expression profile from short-term caloric restriction in mouse adipose tissue |
-2.3 | | Tlcd4 | '120 day; Sod1 G93A' vs '120 day; wild type genotype' | age, genotype | Transcription profiling of astrocytes from the symptomatic and late-stage time points of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis (ALS) |
2.3 | | Tlcd4 | 'T-cell depleted bone marrow transplant' vs 'none' in 'normal' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
2.2 | | Tlcd4 | 'proliferating progenitor' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
2.2 | | Tlcd4 | '14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
2.2 | | Tlcd4 | 'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
2.2 | | Tlcd4 | 'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
-2.2 | | Tlcd4 | 'B.D(Chr5)' vs 'C57BL/6' | strain | Gene expression in Lineage negative bone marrow cells of C57B/L6 and B.D(Chr5) mice |
2.2 | | Tlcd4 | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
2.2 | | Tlcd4 | '30 percent caloric restriction' vs 'control' | diet | Gene expression profile from short-term caloric restriction in mouse adipose tissue |
-2.2 | | Tlcd4 | '20 day; Ad-VEGF-A164' vs '0 day; control' | time, treatment | Transcription profiling by array of stromal-based signatures for the classification of gastric cance |
-2.2 | | Tlcd4 | 'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs' | growth condition | RNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs |
-2.2 | | Tlcd4 | 'uterine-specific Tsc2-null' vs 'wild type' in '17beta-estradiol' | genotype, treatment | Transcription profiling by high throughput sequencing of uterine-specific Tsc2-null mice |
2.1 | | Tlcd4 | 'LDB1 knock-down with full-length Ldb1 construct' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
-2.1 | | Tlcd4 | 'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+' | compound, genotype | Polycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos) |
-2.1 | | Tlcd4 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
2.1 | | Tlcd4 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
2 | | Tlcd4 | 'Irx3 knockout' vs 'control' at '1 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
-2 | | Tlcd4 | 'lung carcinoma' vs 'normal' in 'lung cell' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
2 | | Tlcd4 | 'AZD7507; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
1.9 | | Tlcd4 | 'induced neuronal cell' vs 'pluripotent embryonic stem cell' | phenotype | Transcription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells |
-1.9 | | Tlcd4 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.9 | | Tlcd4 | 'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.9 | | Tlcd4 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
1.9 | | Tlcd4 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
1.9 | | Tlcd4 | 'cetrorelix; 3 milligram per kilogram' vs 'none' in 'inh-alpha/Tag transgenic' | compound, genotype | Novel genes involved in the pathophysiology of gonadotropin-dependent adrenocortical tumorigenesis in mice. |
-1.8 | | Tlcd4 | 'Npas4 shRNA' vs 'control shRNA' at '3 hour' | RNA interference, time | RNAi profiling of mouse hippocampal neurons infected with lentivirus expressing Npas4-RNAi or control-RNAi to study Npas4-regulated genes |
-1.8 | | Tlcd4 | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-1.8 | | Tlcd4 | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-1.8 | | Tlcd4 | 'high fat diet' vs 'normal' | diet | Gene expression changes in Ahnak knockout mice |
-1.8 | | Tlcd4 | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-1.8 | | Tlcd4 | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-1.7 | | Tlcd4 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'CAST/EiJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.7 | | Tlcd4 | 'confluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1.7 | | Tlcd4 | 'induce erythroid differentiation' vs 'none' in 'Runx1 knockdown' | genotype, stimulus | Transcription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor |
1.7 | | Tlcd4 | 'heart-specific p53 knockout; 7 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
1.7 | | Tlcd4 | 'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
1.6 | | Tlcd4 | 'interferon gamma; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
1.6 | | Tlcd4 | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-1.6 | | Tlcd4 | 'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1.6 | | Tlcd4 | 'Npas4 shRNA' vs 'control shRNA' at '1 hour' | RNA interference, time | RNAi profiling of mouse hippocampal neurons infected with lentivirus expressing Npas4-RNAi or control-RNAi to study Npas4-regulated genes |
-1.6 | | Tlcd4 | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-1.6 | | Tlcd4 | 'poly(I:C)' vs 'none' | stimulus | 3’-Seq of ex vivo isolated mouse multipotent steady state hematopoietic stem cells (sHSC) and proliferating HSCs |
1.6 | | Tlcd4 | 'Fancc-/-' vs 'wild type' | genotype | Transcription profiling by array of bone marrow cells from wild type, Fancc-deficient, Fancg-deficient, and doubly deficient (Fancc/Fancg) mice |
-1.6 | | Tlcd4 | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1.6 | | Tlcd4 | 'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte' | cell type, compound, genotype | Transcription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin |
1.5 | | Tlcd4 | 'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
1.5 | | Tlcd4 | 'interferon gamma; 10 nanogram per milliliter and interleukin-22; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
1.5 | | Tlcd4 | 'overexpression of alpha- and beta- Hb chains' vs 'control vector' | genotype | Unexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells |
-1.5 | | Tlcd4 | 'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
-1.5 | | Tlcd4 | 'dinitrofluorobenzene' vs 'control' in 'Cnr1 -/- /Cnr2 -/-' | compound, genotype | Transcription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity |
-1.5 | | Tlcd4 | 'Npas4 shRNA' vs 'control shRNA' at '6 hour' | RNA interference, time | RNAi profiling of mouse hippocampal neurons infected with lentivirus expressing Npas4-RNAi or control-RNAi to study Npas4-regulated genes |
1.5 | | Tlcd4 | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
1.5 | | Tlcd4 | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
1.5 | | Tlcd4 | 'Zfx fl/y CreER; infected with Myc expressing and control retrovirus with GFP selectable marker' vs 'wild type; infected with Myc expressing and control retrovirus with GFP selectable marker' | genotype, treatment | Effect of genetic Zfx deletion on Myc induced gene expression in bone marrrow myeloid progenitors |
1.5 | | Tlcd4 | 'PTIP knockout' vs 'control' | genotype | Transcription profiling by array of mouse cardiac tissue mutant for PTIP |
-1.4 | | Tlcd4 | 'upf3 knockout' vs 'wild type' in 'testis' | cell type, genotype | UPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs |
-1.4 | | Tlcd4 | 'hyperthermia' vs 'control' | treatment | Transcription profiling of mouse Jardine SIDS Model |
1.4 | | Tlcd4 | 'mutant (Pdgfc-/-; Pdgfra GFP/+)' vs 'control' | genotype | Cerebral gene expression changes in Pdgfc and Pdgfra mutant |
1.4 | | Tlcd4 | '10 day' vs '0 day' | age | Transcriptional profiling by array of mouse cerebellar cortex during postnatal development |
-1.4 | | Tlcd4 | 'chronic cystitis' vs 'none' in 'C57/Bl6' | disease, strain | Chronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression |
-1.4 | | Tlcd4 | 'Npas4 shRNA' vs 'control shRNA' at '0 hour' | RNA interference, time | RNAi profiling of mouse hippocampal neurons infected with lentivirus expressing Npas4-RNAi or control-RNAi to study Npas4-regulated genes |
-1.4 | | Tlcd4 | 'lymphocytic choriomeningitis virus WE' vs 'normal' | disease | Transcription profiling by array of lymphocytic choriomeningitis virus-strain WE (LCMV-WE) infected mice versus naive mice. |
1.4 | | Tlcd4 | 'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-' | age, diet, genotype | Tissue-autonomous regulation of adipose expansion by core clock protein REVERBα |
1.4 | | Tlcd4 | '11beta-HSD knockout' vs 'wild type' in 'subcutaneous adipose tissue' | genotype, organism part | Transcription profiling of adipose tissue from mesenteric and subcutaneous depots from 11beta-HSD1 knockout and wild type mice |
-1.3 | | Tlcd4 | 'CEBPa K159R/K298R expression' vs 'wild type CEBPa expression' | genotype | Transcriptome profiling of wild type, K159/298Q- and K159/298R- C/EBPα expressing mouse cells |
-1.3 | | Tlcd4 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in '129S1/SvImJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
1.3 | | Tlcd4 | 'NHD13 mutant' vs 'wild type' | genotype | Myelodysplastic syndrome: NUP98-HoxD13 (NHD13) expression effect on hematopoietic stem cells |
1.3 | | Tlcd4 | 'ATF5 knockdown' vs 'wild type' in 'DMSO' | compound, genotype | Microarray to find ATF5 dependent genes in response to proteasome inhibition |
1.3 | | Tlcd4 | '7 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-1.3 | | Tlcd4 | 'parous' vs 'virgin' | clinical history | Transcription profiling of mammary glands from virgin or parous FVB strain mice |
1.3 | | Tlcd4 | 'osteoblast culture 27 day' vs '0 day' | time | Transcription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation |
1.3 | | Tlcd4 | 'stromal cell; E2' vs 'stromal cell; vehicle' | cell type, treatment | Affymetrix gene chip analysis for the whole mouse genome transcripts of epithelial and stromal cells from mouse uterine primary co-culture treated with either vehicle or E2 |
1.3 | | Tlcd4 | 'calorie restricted diet' vs 'normal diet' at '15 month' | age, diet | Transcription profiling by array of cochleae from mice fed a calorie-restricted diet |
1.3 | | Tlcd4 | 'CD47 knockdown; endothelial’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
-1.3 | | Tlcd4 | 'damaged by neuropathy' vs 'control' | sampling site | Transcriptional profiling of damaged and adjacent but intact dorsal root ganglia neurons against DRG cells from contralacteral control regions from mice with neuropathy |
1.3 | | Tlcd4 | 'double Fancc-/- Fancg-/-' vs 'wild type' | genotype | Transcription profiling by array of bone marrow cells from wild type, Fancc-deficient, Fancg-deficient, and doubly deficient (Fancc/Fancg) mice |
1.3 | | Tlcd4 | '22 to 23 month' vs '2 to 3 month' | age | Transcription profiling by array of long-term haematopoietic stem cells from old and young mice |
-1.2 | | Tlcd4 | '129S1 allele at SNP rs50454566' vs 'wild type genotype' | genotype | RNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene |
-1.2 | | Tlcd4 | 'mdx' vs 'wild type' in 'postnatal day 56' | developmental stage, genotype | Transcription profiling of mouse hindlimb muscle, comparison of wild type and mdx mice, 7 to 112 Day |
1.2 | | Tlcd4 | 'fasted' vs 're-fed' in 'wild type genotype; Gabpa miRNA' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
-1.2 | | Tlcd4 | 'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.2 | | Tlcd4 | '18 week; Str/ort' vs '18 week; CBA' | age, strain | Expression data of cartiliage from CBA and STR/ORT mice |
1.2 | | Tlcd4 | 'Fancg-/-' vs 'wild type' | genotype | Transcription profiling by array of bone marrow cells from wild type, Fancc-deficient, Fancg-deficient, and doubly deficient (Fancc/Fancg) mice |
1.2 | | Tlcd4 | 'Sik1 knockout; gonad adipose tissue' vs 'wild type genotype; gonad adipose tissue' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
-1.2 | | Tlcd4 | 'heart-specific p53 and Mdm2 knockout; 7 day' vs 'heart-specific p53 and Mdm2 knockout; 1 day' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
1.1 | | Tlcd4 | 'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
1.1 | | Tlcd4 | 'intermittent fasting every 16 hours' vs 'ad libitum' | diet | Genome-Wide Transcriptome Analysis Reveals Intermittent Fasting-Induced Metabolic Rewiring in the Liver |
-1.1 | | Tlcd4 | 'Psen 1 and 2 null' vs 'wild type' | genotype | Quantitative Analysis of Notch mutant (Notch1&2-null, Psen1&2-null, RBPjk-null) and wild-type hair follicle transcriptomes by NGS |
-1.1 | | Tlcd4 | 'Tgfbeta inhibitor 20 micromolar' vs 'none' | compound | Expression data from intestinal organoids altered for Tgfbeta signaling |
-1.1 | | Tlcd4 | 'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1.1 | | Tlcd4 | 'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day' | compound, genotype, time | Transcription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin |
1.1 | | Tlcd4 | 'Pax7 driven Mef2a overexpression' vs 'wild type' | phenotype | Metabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk-Dio3 mega gene cluster. |
1.1 | | Tlcd4 | 'Meis1; Meis2 conditional knockout' vs 'wild type phenotype' | phenotype | Meis homeobox genes control cell competence within the eye-specified neuroepithelium (RNA-seq) |
-1.1 | | Tlcd4 | 'R6/2 transgenic' vs 'wild type' in '8 week; brain cortex' | age, genotype, organism part | Transcription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks. |
-1.1 | | Tlcd4 | 'myeloid progenitor cell; FoxO1/3/4 triple knockout' vs 'myeloid progenitor cell; wild type genotype' | cell type, genotype | Transcription profiling of bone marrow hematopoietic stem cells and myeloid progenitors from mice with conditional deletion of Forkhead O (FoxO) family of transcription factors |
-1.1 | | Tlcd4 | '9 day' vs '0 day' | time | Transcription profiling by array of mineralising murine vascular smooth muscle cell cultures over a nine day culture period to identify new regulators of vascular mineralization |
-1.1 | | Tlcd4 | 'tumor' vs 'normal' in 'liver' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
1.1 | | Tlcd4 | 'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; embryonic day 14.5' vs 'Lin- CD44+ CD25- c-Kit+ thymocyte progenitor cell; adult' | cell type, developmental stage | Transcription profiling of mouse adult and fetal T cell progenitors |
-1.1 | | Tlcd4 | 'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1.1 | | Tlcd4 | 'p48-Cre;KrasG12D;Ela-Tgfa' vs 'wild type' | genotype | Transcription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice |
-1.1 | | Tlcd4 | 'CD34+ keratinocyte' vs 'CD34-keratinocyte' | cell type | Akt signalling leads to stem cell activation and promotes tumour development in epidermis. |
1.1 | | Tlcd4 | 'embryonic day 16.5' vs 'embryonic day 11.5' | developmental stage | Gene expression profile of diaphragm morphogenesis at different developmental stages |
-1.1 | | Tlcd4 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.1 | | Tlcd4 | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.1 | | Tlcd4 | "chronic exposure to downstream water" vs "chronic exposure to control water" | environmental history, generation | Toxicogenomic analysis in liver of mice exposed to polluted groundwater |
1 | | Tlcd4 | 'postnatal day 4' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1 | | Tlcd4 | 'beta cell specific Pax6 knockout' vs 'wild type' | phenotype | RNA-Seq of pancreatic islets from beta cell-specific Pax6 knockout mice |
-1 | | Tlcd4 | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1 | | Tlcd4 | 'epithelium-specific mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
1 | | Tlcd4 | 'phosgene - carbonyl chloride' at '48 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury |
-1 | | Tlcd4 | 'Influenza A virus' vs 'mock' in 'interleukin-22' | infect, stimulus | Transcription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza |
-1 | | Tlcd4 | 'Rev-erb alpha knockout' vs 'wild type' | genotype | Transcription profiling by array of epididymal white adipose tissue of Rev-erb alpha knockout mouse |
-1 | | Tlcd4 | 'Alk5 fl/fl; Wnt1-Cre' vs 'control' | genotype | Gene expression profiling of the tongue bud from Alk5 mutant mouse models |
-1 | | Tlcd4 | 'AR3 transgenic' vs 'wild type' | genotype | Expression data from AR3 transgenic and wild-type mouse prostates |
-1 | | Tlcd4 | '4 day' vs '1 day' in 'influenza A infected DBA/2J' | disease, strain, time | Transcription profiling by array of flu-infected lungs of DBA/2J and C57BL/6J mice 1 to 4 days post infection |
-1 | | Tlcd4 | 'left ventricle' vs 'right ventricle' in 'embryonic day 9.5' | developmental stage, organism part | Transcriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome |
1 | | Tlcd4 | 'active Sendai virus' vs 'UV-inactivated Sendai virus' at '49 day' on 'Affymetrix Mouse430_2 Array' | infect, time | Transcription profiling by array of lungs from C57BL/6J mice infected with Sendai virus |
-1 | | Tlcd4 | 'Crx knockout' vs 'control' at '6 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
1 | | Tlcd4 | 'control mice [Gp130f/f]; cecal ligation and puncture' vs 'control mice [Gp130f/f]; control' | genotype, treatment | Hepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function |
1 | | Tlcd4 | 'heart-specific p53 knockout; 28 day' vs 'wild type phenotype' | phenotype, time | Transcription profiling of heart tissue from mice with heart-specific knockout of p53 and Mdm2 |
-1 | | Tlcd4 | 'utrophin/distrophin double knockout' vs 'distrophin knockout' in 'hindlimb muscle' | genotype, organism part | Transcription profiling of extraocular, hindlimb and cardiac muscles from dKO and MDX mice |
1 | | Tlcd4 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1 | | Tlcd4 | 'sciatic nerves at the midtight level crushed by compression' vs 'none' in 'wild type; gastrocnemius' | clinical treatment, genotype, organism part | Gene expression profiling of muscles from transgenic humanSODG93A mice at symptomatic stage |
-1 | | Tlcd4 | 'beta(3)-adrenergic agonist Cl316,243' vs 'none' at '76 week' | age, stimulus | RNA-seq of age-associated transcriptome changes in brown adipose tissue |
1 | | Tlcd4 | 'inhibitor of kappaB kinase beta constitutively active' vs 'wild type' | phenotype | Transcription profiling by array of primary murine cardiomyocytes with and without expression of constitutively active IKK2 |
-1 | | Tlcd4 | 'Gata6 knockout' vs 'wild type' | phenotype | Global gene expression in the adult Gata6 null mouse pancreas |
1 | | Tlcd4 | 'adipose tissue specific Trim28 knockout' vs 'wild type genotype' in 'male' | genotype, sex | RNA-seq of gonadal adipose tissue from male and female Trim28-WT and Trim28 adipose specific KO mice |
-1 | | Tlcd4 | 'Albumin Cre+/-;Hnf4a fl/fl' vs 'wild type genotype' | genotype | Transcription profiling by array of liver-specific Hnf4alpha knock-out mice |
