ensmusg00000036892 (Prodh2)

mus musculus

proline dehydrogenase (oxidase) 2

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Mus musculus
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Showing 35 experiments:
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - neonate
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 14
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Mammalian Kaessmann
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9
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 13
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Vertebrates
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Developing gut
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6
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49 FANTOM5 project - adult
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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3 Soumillon et al
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - C57BL/6J
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Organism part - Geiger et al
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Organism part - Huttlin et al
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Organism part - Malmstrom et al - , …
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Huttlin et al., 2010 - tissues - brain, …
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Organism part - Malmstrom et al - …
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Organism part - Malmstrom et al - , …
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Meierhofer et al., 2016 - organism part
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
2.6068 × 10-46.3
Prodh2'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
5.081 × 10-18-5.4
Prodh2'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
2.0244 × 10-314.3
Prodh2'Ffar3 knockout' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of pancreatic islets isolated from free fatty acid receptor 3 knockout (Ffar3 KO) and wild type (Ffar3 WT) male mice
Adjusted p-valueLog2-fold change
1.1293 × 10-11-4
Prodh2'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells'age, cell typeTranscriptional profiling of nascent and mature pancreatic beta cells
Adjusted p-valueLog2-fold change
3.8387 × 10-5-4
Prodh2'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
8.2477 × 10-11-3.9
Prodh2'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.9174 × 10-10-3.5
Prodh2'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.779 × 10-8-3.5
Prodh2'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.009 × 10-8-3.4
Prodh2'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.6843 × 10-6-3.4
Prodh2'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
5.0684 × 10-5-3
Prodh2'Albumin Cre+/-;Hnf4a fl/fl' vs 'wild type genotype'genotypeTranscription profiling by array of liver-specific Hnf4alpha knock-out mice
Adjusted p-valueLog2-fold change
2.1338 × 10-23
Prodh2'AZD5069; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
2.7086 × 10-12-2.9
Prodh2'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
1.2185 × 10-9-2.9
Prodh2'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.4477 × 10-9-2.9
Prodh2'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.7379 × 10-44-2.8
Prodh2'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.3862 × 10-2-2.8
Prodh2'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
4.8671 × 10-22.7
Prodh2'vaccination' vs 'adjuvant only' in 'Plasmodium chabaudi infection'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
1.141 × 10-8-2.6
Prodh2'confluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.3614 × 10-8-2.6
Prodh2'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
7.3621 × 10-4-2.6
Prodh2'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
5.9288 × 10-3-2.5
Prodh2'pabpn1l -/-' vs 'wild type genotype' in 'zygote'genotype, organism partRNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice
Adjusted p-valueLog2-fold change
1.7714 × 10-22.4
Prodh2'TRIM28(flox/flox):Mx1Cre' vs 'TRIM28(flox/flox)' in 'CD71(hi)TER119+'genotype, phenotypeTranscription profiling by high throughput sequencing of bone marrow immature erythroid cells from Trim28flox/flox:TgMx1Cre congenic mice
Adjusted p-valueLog2-fold change
1.4206 × 10-7-2.3
Prodh2'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.7168 × 10-22.3
Prodh2'AZD7507; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
2.8183 × 10-7-2.2
Prodh2'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
4.5231 × 10-2-2.2
Prodh2'H-Ras expression' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
1.3571 × 10-4-2
Prodh2'Nippostrongylus brasiliensis' vs 'none'infectRNAseq of small intestinal epithelium extracted from mice infected with Nippostrongylus brasiliensis
Adjusted p-valueLog2-fold change
2.1675 × 10-2-2
Prodh2'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector'genotypeRNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice
Adjusted p-valueLog2-fold change
7.2328 × 10-4-1.9
Prodh2'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.7784 × 10-41.8
Prodh2'Nrl-/-' vs 'wild type'genotypeNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Nrl-/- Retinal Transcriptomes
Adjusted p-valueLog2-fold change
3.8676 × 10-3-1.8
Prodh2'tumor' vs 'normal' in 'liver'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.6989 × 10-7-1.7
Prodh2'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.4795 × 10-2-1.6
Prodh2'epithelium-specific Apc knockout' vs 'wild type'phenotypeRNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin
Adjusted p-valueLog2-fold change
1.4926 × 10-5-1.4
Prodh2'ko cyld-/-' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Cyld inactivation
Adjusted p-valueLog2-fold change
9.6335 × 10-4-1.4
Prodh2'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
1.773 × 10-2-1.4
Prodh2'Alb-Cre;VHLf/f' vs 'Alb-Cre'genotypeTranscription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor
Adjusted p-valueLog2-fold change
2.0098 × 10-2-1.4
Prodh2'Alb-Cre;HIF1dPA/HIF2dPA' vs 'Alb-Cre'genotypeTranscription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor
Adjusted p-valueLog2-fold change
8.2293 × 10-5-1.3
Prodh2'methionine- and choline-deficient, high fat diet' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
1.9537 × 10-3-1.3
Prodh2'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
1.1842 × 10-2-1.3
Prodh2'hepatocyte-specific Pten knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
8.7185 × 10-61.2
Prodh2'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
1.1546 × 10-4-1.2
Prodh2'postnatal day 4' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
9.9384 × 10-3-1.2
Prodh2'Pten knockout' vs 'wild type' at '15 month'genotype, timeTranscription profiling by array of Pten knockout liver cells of mouse
Adjusted p-valueLog2-fold change
4.7872 × 10-2-1.2
Prodh2'14 month; QH2; kidney' vs '14 month; control; kidney'age, compound, organism partCoenzyme Q10-dependent gene expression in SAMP1 mice tissues
Adjusted p-valueLog2-fold change
7.9062 × 10-16-1.1
Prodh2'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
2.6347 × 10-5-1.1
Prodh2'methionine- and choline-deficient, high fat diet mixed with 0.1% metformin' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
3.6982 × 10-5-1.1
Prodh2'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
1.7082 × 10-4-1.1
Prodh2'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
6.2541 × 10-41.1
Prodh2'14 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.2629 × 10-2-1.1
Prodh2'Insm1-expressing endocrine progenitor cell' vs 'Insm1-lacking endocrine progenitor cell' in 'embryonic day 15.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
4.2221 × 10-21.1
Prodh2'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
2.7128 × 10-31
Prodh2'7 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
3.4623 × 10-2-1
Prodh2'Rb^{lox/lox}; p130^{lox/lox}; p107+/-' vs 'wild type'genotypeTranscription profiling by array of livers from the mouse model of human hepatocellular carcinoma
Adjusted p-valueLog2-fold change
4.025 × 10-2-1
Prodh2'Timp3-/-' vs 'wild type genotype'genotypeTranscription profiling by array of kidneys from diabetic wild type and T3-/- mice