ensmusg00000036442 (Thap11)

mus musculus

THAP domain containing 11

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Mus musculus
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Showing 31 experiments:
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Created with Highcharts 6.2.0adrenal glandbraincerebral cortexdiencephalonepididymis and seminiferous tubuleheartlateral nasal prominencemedial nasal prominencenon-floor plate neural epitheliumpancreasskeletal muscle tissuetestisvesicular glandaxillary lymph nodecaudal brain neural epitheliumcorpus striatumduodenumfloor plateintestinal mucosalungmidbrainolfactory pitrenal medullaspleenurinary bladderzone of skin
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - adult
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 18
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Vertebrates
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Mammalian Kaessmann
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9
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6
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 13
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3 Soumillon et al
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14 - embryonic day 8.5
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14 - embryonic day 10.5
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - C57BL/6J
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Organism part - Huttlin et al
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Organism part - Malmstrom et al - , …
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Organism part - Geiger et al
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Huttlin et al., 2010 - tissues - brain, …
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Organism part - Malmstrom et al - , …
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Organism part - Malmstrom et al - , …
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Meierhofer et al., 2016 - organism part
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Proteomics
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Transcriptomics
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-3.8
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.0326 × 10-4-3.8
Thap11'metaphase II oocyte' vs 'germinal vesicle oocyte'cell typeTranscription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming
Adjusted p-valueLog2-fold change
4.4789 × 10-3-2.1
Thap11'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.2171 × 10-4-1.9
Thap11'cycloheximide and 100 unit per milliliter interferon gamma' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
9.5491 × 10-3-1.9
Thap11'subventicular zone of the lateral ventricle' vs 'cerebellum'organism partExpression data from adult Shh-responding astroglia cells in mice
Adjusted p-valueLog2-fold change
1.6741 × 10-7-1.7
Thap11'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
6.9818 × 10-4-1.7
Thap11'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
7.2092 × 10-61.5
Thap11'TUT4 deficiency; TUT7 knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
2.0465 × 10-41.5
Thap11'chemical hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo.
Adjusted p-valueLog2-fold change
2.4055 × 10-30-1.4
Thap11'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
2.9125 × 10-23-1.4
Thap11'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.6297 × 10-4-1.4
Thap11'cycloheximide and 100 unit per milliliter interferon alpha' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
2.6421 × 10-4-1.4
Thap11'cycloheximide' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
2.2184 × 10-2-1.4
Thap11'hippocampus' vs 'cerebellum'organism partExpression data from adult Shh-responding astroglia cells in mice
Adjusted p-valueLog2-fold change
1.9653 × 10-151.3
Thap11'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.5197 × 10-8-1.3
Thap11'Kit ligand' vs 'none' in 'wasp knockout'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
6.0632 × 10-5-1.3
Thap11'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-'compound, genotypeInhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2)
Adjusted p-valueLog2-fold change
9.176 × 10-31.3
Thap11'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
2.2404 × 10-32-1.2
Thap11'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
4.652 × 10-10-1.2
Thap11'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
3.4261 × 10-7-1.2
Thap11'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
7.0375 × 10-71.2
Thap11'butyrate' vs 'none'compoundHDAC inhibition by TSA and Butyrate In Flt3L-elicited DC
Adjusted p-valueLog2-fold change
1.4422 × 10-51.2
Thap11'TUT4; TUT7 double knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
1.5937 × 10-4-1.2
Thap11'polarized with E coli lipopolysacharide and INF-gamma' vs 'untreated'compound, treatmentExpression data from polarized macrophages: effect of p53
Adjusted p-valueLog2-fold change
3.9521 × 10-41.2
Thap11'E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
5.2572 × 10-41.2
Thap11'Rb;E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.5842 × 10-16-1.1
Thap11'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.4082 × 10-101.1
Thap11'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.2425 × 10-7-1.1
Thap11'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
8.8425 × 10-71.1
Thap11'trichostatin A' vs 'none'compoundHDAC inhibition by TSA and Butyrate In Flt3L-elicited DC
Adjusted p-valueLog2-fold change
2.1053 × 10-5-1.1
Thap11'Porphyromonas gingivalis; normal' vs 'normal'infect, phenotypehyperlipidemia impaired innate response
Adjusted p-valueLog2-fold change
1.0078 × 10-4-1.1
Thap11'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
6.0031 × 10-8-1
Thap11'Kit ligand' vs 'none' in 'wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
4.7463 × 10-41
Thap11'dibenzazapine 10 micromoles per kilogram' vs 'none'compound, doseTranscription profiling by array of pancreatic cells from C57BL/6 mice following dibenzazepine treatment
Adjusted p-valueLog2-fold change
7.4142 × 10-4-1
Thap11'control mice [Gp130f/f]; cecal ligation and puncture' vs 'control mice [Gp130f/f]; control'genotype, treatmentHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Adjusted p-valueLog2-fold change
6.1394 × 10-31
Thap11'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
6.379 × 10-31
Thap11'Stella maternal / zygotic knockout' vs 'wild type genotype' in '1-cell embryo'developmental stage, genotypeTranscription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development
Adjusted p-valueLog2-fold change
6.4335 × 10-31
Thap11'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '120 minute'compound, genotype, timeTranscription profiling by array of fibroblasts from TTP knock out mice
Adjusted p-valueLog2-fold change
7.3391 × 10-3-1
Thap11'megakaryocyte' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
2.9808 × 10-2-1
Thap11'recombinant human interleukin-2; 100 unit per milliliter; 2 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2