-7.5 | | Nupl2 | 'Cox6a2 knockout' vs 'wild type' | phenotype | RNA-seq of PV+ interneurons in WT and Cox6a2-/- mice to unravel the molecular signaling that contributes to the increase in oxidative stress and metabolic dysregulation following Cox6a2 knockout. |
-5.3 | | Nupl2 | 'Lin- Dapi-EpCAM- CD31+td-tomato+' vs 'Lin- Dapi-EpCAM- CD31+td-tomato-' in 'vascular endothelial cell' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
5.1 | | Nupl2 | '19 to 22 month' vs '3 to 4 month' in 'endothelial cell' | age, cell type | RNA-seq of 5 populations from the regenerative region of the brain of young and old mice |
-2.5 | | Nupl2 | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
-2.1 | | Nupl2 | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
-2 | | Nupl2 | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.7 | | Nupl2 | 'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
-1.7 | | Nupl2 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.4 | | Nupl2 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.4 | | Nupl2 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.3 | | Nupl2 | 'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
-1.3 | | Nupl2 | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.3 | | Nupl2 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-1.2 | | Nupl2 | 'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.2 | | Nupl2 | 'granulocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
1.1 | | Nupl2 | 'db/db' vs 'wild type genotype' in 'Gabpa miRNA; fasted' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
-1.1 | | Nupl2 | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-1.1 | | Nupl2 | 'B6.Sle1a.1' vs 'wild type' | genotype | Transcription profiling by array of mouse CD4+ T cells mutant for Sle1a.1 |
-1.1 | | Nupl2 | 'bER knockout' vs 'wild type' in 'human chorionic gonadotropin; 5 International Unit' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
-1 | | Nupl2 | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
1 | | Nupl2 | 'Lmna G609G/G609G knock in' vs 'wild type' | genotype | Transcription profiling by array of mouse liver with Lmna Gly609Gly knock in |
-1 | | Nupl2 | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
1 | | Nupl2 | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-1 | | Nupl2 | 'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar' | compound, genotype | Overexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment |
