ensmusg00000030098 (Grip2)

mus musculus

glutamate receptor interacting protein 2

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Mus musculus
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Showing 42 experiments:
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.9041 × 10-2-7.1
Grip2'Cox6a2 knockout' vs 'wild type'phenotypeRNA-seq of PV+ interneurons in WT and Cox6a2-/- mice to unravel the molecular signaling that contributes to the increase in oxidative stress and metabolic dysregulation following Cox6a2 knockout.
Adjusted p-valueLog2-fold change
2.0151 × 10-56.1
Grip2'Lin- Dapi-EpCAM- CD31+td-tomato+' vs 'Lin- Dapi-EpCAM- CD31+td-tomato-' in 'vascular endothelial cell'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
3.637 × 10-4-5.8
Grip2'Zbtb10 knockdown' vs 'control' at '2 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
1.3341 × 10-1965.5
Grip2'neuron' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
2.9856 × 10-13-5.3
Grip2'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
4.2155 × 10-3-4.9
Grip2'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
4.2084 × 10-24.9
Grip2'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
3.0054 × 10-3-4.6
Grip2'Zbtb10 knockdown' vs 'control' at '6 hour'genotype, timeRNA-seq of Zbtb10 Knockdown and Control cDC1 dendritic cells (Cd8+)
Adjusted p-valueLog2-fold change
7.3301 × 10-7-3.9
Grip2'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.8024 × 10-3-3.9
Grip2'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
4.5086 × 10-7-3.3
Grip2'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.2639 × 10-23.2
Grip2'dexamethasone; 10 microgram per milliliter' vs 'none'compoundRNA-seq of mouse sciatic peripheral nerve of injured mouse with implant: control (untreated) vs local delivery of MCC950 (NLRP3inh) vs standard FBR treatment dexamethasone (Dex). .
Adjusted p-valueLog2-fold change
1.454 × 10-32.9
Grip2'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
6.3841 × 10-72.6
Grip2'10 Gy Gray; x-ray' vs 'none' in 'tumor and stromal cell'cell type, irradiateRNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated
Adjusted p-valueLog2-fold change
1.5693 × 10-22.6
Grip2'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
3.4783 × 10-22.6
Grip2'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
4.9756 × 10-62.5
Grip2'carotid body' vs 'adrenal medulla'organism partExpression profile of mouse carotid body and adrenal medulla [RNA-Seq]
Adjusted p-valueLog2-fold change
5.3885 × 10-6-2.5
Grip2'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
3.7857 × 10-3-2.5
Grip2'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
6.0609 × 10-3-2.5
Grip2'21 percent oxygen, 37 degree Celsius, no serum' vs 'none'growth conditionRNA sequencing of native and ex vivo cultured murine tail tendon fascicles
Adjusted p-valueLog2-fold change
2.8055 × 10-22.4
Grip2'T-cell depleted bone marrow transplant' vs 'none' in 'normal'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
5.3997 × 10-10-2.3
Grip2'Abcc8-/-' vs 'wild type genotype' in 'normal; male'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
3.0206 × 10-3-2.1
Grip2'Irx3 knockout' vs 'control' at '1 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.3971 × 10-4-2
Grip2'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.5637 × 10-13-1.9
Grip2'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.8834 × 10-7-1.9
Grip2'Abcc8-/-' vs 'wild type genotype' in 'normal; female'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
7.6887 × 10-5-1.9
Grip2'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
4.7576 × 10-21.9
Grip2'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
4.0415 × 10-101.8
Grip2'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
8.711 × 10-10-1.8
Grip2'Abcc8 knockout' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of pancreatic beta cells from wild type and Abcc8 knockout mice
Adjusted p-valueLog2-fold change
7.402 × 10-6-1.7
Grip2'SARS coronavirus MA15; 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.6721 × 10-5-1.7
Grip2'H-Ras expression; c-Myc activation' vs 'wild type'phenotypeRNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.
Adjusted p-valueLog2-fold change
2.2448 × 10-51.7
Grip2'1810027O10Rik knockout; gonad adipose tissue' vs 'wild type genotype; gonad adipose tissue'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
4.3127 × 10-6-1.6
Grip2'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
3.7154 × 10-21.6
Grip2'Nutlin-3a; 150 milligram per kilogram per day' vs 'none' in 'p53 heterozygous mutant'compound, phenotypeRNA-seq of mouse colon to investigate how suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity
Adjusted p-valueLog2-fold change
5.1768 × 10-22-1.5
Grip2'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
7.4743 × 10-4-1.5
Grip2'ductus arteriosis' vs 'aorta'organism partGene Profiling in Mouse Fetal Ductus Arteriosus
Adjusted p-valueLog2-fold change
4.1848 × 10-6-1.3
Grip2'3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
2.2718 × 10-5-1.3
Grip2'Notch3 homozygous knockout' vs 'wild type genotype' in 'cerebellar microvascular fragments'genotype, organism partTranscription profiling by array of cerebral and cerebellar microvascular fragments from mice with Notch3 homozygous knockout vs samples from control, wild-type littermates
Adjusted p-valueLog2-fold change
4.9051 × 10-5-1.3
Grip2'Notch3 knockout' vs 'wild type'genotypeExpression data from caudal artery of Notch3WT and Notch3KO mice
Adjusted p-valueLog2-fold change
4.8348 × 10-2-1.3
Grip2'SARS coronavirus MA15; 2 day' vs 'mock' in '129S1/SvImJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
2.9226 × 10-5-1.2
Grip2'Notch3 homozygous knockout' vs 'wild type genotype' in 'cerebral microvascular fragments'genotype, organism partTranscription profiling by array of cerebral and cerebellar microvascular fragments from mice with Notch3 homozygous knockout vs samples from control, wild-type littermates
Adjusted p-valueLog2-fold change
3.3309 × 10-3-1.2
Grip2'Reverbα-/- global knockout' vs 'Reverbα wild type' in 'not applicable; 13 week'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
1.0775 × 10-2-1.2
Grip2'120 day; Sod1 G93A' vs '120 day; wild type genotype'age, genotypeTranscription profiling of astrocytes from the symptomatic and late-stage time points of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis (ALS)
Adjusted p-valueLog2-fold change
2.9332 × 10-2-1.2
Grip2'SARS coronavirus MA15; 2 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
1.256 × 10-5-1.1
Grip2'Adrb1, Adrb2 and Adrb3 knockout' vs 'wild type genotype' in '15 degree celsius'genotype, temperatureRNA-seq of cold-induced transcriptome changes in skeletal muscle of beta-adrenergic receptor knockout mice
Adjusted p-valueLog2-fold change
6.2618 × 10-3-1.1
Grip2'Abcc8-/-' vs 'wild type genotype' in 'high fat; female'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
1.2949 × 10-2-1.1
Grip2'cut nerve; 7 day' vs 'none'injury, protocol, timeChanges in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury
Adjusted p-valueLog2-fold change
2.8543 × 10-2-1.1
Grip2'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.5896 × 10-61
Grip2'MEF; transduced with MyoD lentivirus' vs 'MEF; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
6.4836 × 10-5-1
Grip2'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
5.967 × 10-3-1
Grip2'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 4 day' vs 'mock' in 'PWK/PhJ'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
7.4511 × 10-31
Grip2'LKB1 knockout; floxed LKB1 with RIP-Cre' vs 'floxed LKB1 without RIP-Cre; wild type'genotype, phenotypeTranscription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice