ensmusg00000023902 (Zscan10)

mus musculus

zinc finger and SCAN domain containing 10

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Mus musculus
Organism part
Showing 29 experiments:
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Created with Highcharts 6.2.0adrenal glandbraincerebellumdiencephaloneyeball of camera-type eyeileumlateral prominence neural epitheliummedial prefrontal cortexolfactory brainpituitary glandstomachtonguevomeronasal organaxillary lymph nodecaecumcorpora quadrigeminaepidermal ectodermheartintestinemandibular archmuscle (biceps femoris)olfactory pitskeletal muscle tissuesubventricular zoneuterus
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9
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9 in 3 strains - C57BL/6
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14 - embryonic day 10.5
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Mammalian Kaessmann
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6
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Vertebrates
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4
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Developing gut
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3 Soumillon et al
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3
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Sun et al., 2020 - Organism part
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - C57BL/6J
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Mernberger et al 2019 - Organism Part
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Fat and muscle
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2
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - adult
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4 Bonthuis et al - Idaho derived wild …
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Proteomics
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Transcriptomics
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
4.4699 × 10-74.6
Zscan10'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.7461 × 10-54.4
Zscan10'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.7215 × 10-54.3
Zscan10'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
4.5467 × 10-54.3
Zscan10'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.2342 × 10-24.1
Zscan10'soticlestat; 30 milligram per kilogram' vs 'none' in 'astrocyte; none'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
1.7545 × 10-2-4
Zscan10'status epilepticus' vs 'none' in 'astrocyte; soticlestat; 30 milligram per kilogram'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
5.9855 × 10-27-3.8
Zscan10'Rfx2 knock out' vs 'wild type genotype'genotypeNext Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes at post natal day 30 [RNA-Seq P30]
Adjusted p-valueLog2-fold change
5.4369 × 10-113.5
Zscan10'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
1.0226 × 10-53.2
Zscan10'V6.5; embryonic stem cell’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
6.0084 × 10-9-2.7
Zscan10'7 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
5.882 × 10-9-2.6
Zscan10'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
4.9845 × 10-32.6
Zscan10'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
2.1771 × 10-85-2.5
Zscan10'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
2.2436 × 10-10-2.5
Zscan10'6 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
4.1065 × 10-62.5
Zscan10'stabilization-competent' vs 'stabilization-incompetent' in '22 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
6.1253 × 10-102.4
Zscan10'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2 and Egr3 knockout'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
8.5102 × 10-52.3
Zscan10'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.6025 × 10-122.2
Zscan10'Tumor Necrosis Factor' vs 'none'stimulusTranscription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor
Adjusted p-valueLog2-fold change
9.4819 × 10-11-2.2
Zscan10'26 day' vs '0 day'ageGene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26)
Adjusted p-valueLog2-fold change
7.6874 × 10-10-2.2
Zscan10'16 day' vs '0 day'ageGene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26)
Adjusted p-valueLog2-fold change
3.2993 × 10-2-2.1
Zscan10'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
8.2017 × 10-3-2
Zscan10'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
7.0326 × 10-9-1.9
Zscan10'5 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.9493 × 10-31.9
Zscan10'tumor' vs 'normal' in 'liver'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
1.1073 × 10-5-1.8
Zscan10'trichostatin A and LIF' at '12 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
4.8544 × 10-7-1.7
Zscan10'336 hour' vs '0 hour' on 'Affymetrix MOE430B Array'timeTranscription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
1.4334 × 10-5-1.6
Zscan10'trichostatin A and LIF' at '6 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
4.8335 × 10-21.6
Zscan10'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.8199 × 10-2-1.5
Zscan10'upf3 knockout' vs 'wild type' in 'testis'cell type, genotypeUPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs
Adjusted p-valueLog2-fold change
4.4574 × 10-6-1.4
Zscan10'168 hour' vs '0 hour' on 'Affymetrix MOE430B Array'timeTranscription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
6.3759 × 10-51.4
Zscan10'Egr2 and Egr3 knockout' vs 'Egr2-GFP knockin; Egr2-GFP high' in 'CD4-positive T cell'cell type, genotype, phenotypeRNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection
Adjusted p-valueLog2-fold change
6.2859 × 10-41.4
Zscan10'stabilization-competent' vs 'stabilization-incompetent' in '21 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
4.6681 × 10-41.3
Zscan10'stabilization-competent' vs 'stabilization-incompetent' in '27 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
6.4525 × 10-4-1.3
Zscan10'embryoid body' vs 'embryonic stem cell' on 'Affymetrix GeneChip Array MOE430B'developmental stageGene expression profile of J1 embryonic stem cells and J1 embryoid bodies
Adjusted p-valueLog2-fold change
1.7693 × 10-3-1.3
Zscan10'Rfx2 knock out' vs 'wild type genotype'genotypeNext Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes at post natal day 21 [RNA-Seq P21]
Adjusted p-valueLog2-fold change
8.3692 × 10-7-1.2
Zscan10'4 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
4.6795 × 10-3-1.2
Zscan10'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens
Adjusted p-valueLog2-fold change
2.8822 × 10-51.1
Zscan10'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.0222 × 10-41
Zscan10'nmf205 mutant' vs 'wild type'genotypeTranscription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/-
Adjusted p-valueLog2-fold change
2.8762 × 10-31
Zscan10'nmf205, Gcn2 double mutant' vs 'wild type'genotypeTranscription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/-
Adjusted p-valueLog2-fold change
1.2295 × 10-21
Zscan10'19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day'cell line, growth condition, timeNatural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines
Synonym
Zfp206, Zscan10
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
5221693, 4384168, 5325593, 4340388, 4980990, 5250122, 5293522, 4661165, A_55_P1970274, 5073760, 5038920, A_55_P1970279, 4811660, A_52_P84674, 5184935, 10442302, 5441938, 5486170, 1438787_at, 4524476, 4430599, ILMN_2858050, 4670345, 17334065