-3.2 | | Lemd3 | 'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+' | compound, genotype | Polycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos) |
-2.7 | | Lemd3 | 'Yersinia pestis' vs 'control' in 'neutrophil' | cell type, infect, sampling site | Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague |
-2.3 | | Lemd3 | 'normobaric hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo. |
1.9 | | Lemd3 | 'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice' | age, time, treatment | Aged Mice are Unable to Mount an Effective Myeloid Response to Sepsis |
-1.9 | | Lemd3 | '120 day; Sod1 G93A' vs '120 day; wild type genotype' | age, genotype | Transcription profiling of astrocytes from the symptomatic and late-stage time points of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis (ALS) |
1.8 | | Lemd3 | 'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
1.8 | | Lemd3 | 'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
-1.8 | | Lemd3 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
1.6 | | Lemd3 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.3 | | Lemd3 | 'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.3 | | Lemd3 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; MEF2C/D knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.2 | | Lemd3 | 'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1.2 | | Lemd3 | 'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-' | compound, genotype | Inhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2) |
1.2 | | Lemd3 | 'control mice [Gp130f/f]; cecal ligation and puncture' vs 'control mice [Gp130f/f]; control' | genotype, treatment | Hepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function |
1.2 | | Lemd3 | 'Fhl1 knockdown by siRNA' vs 'wild type' at '3 day' | phenotype, time | 3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1 |
1.2 | | Lemd3 | 'induction of polymicrobial sepsis' vs 'control' at '72 hour' in '1.5 to 3 month mice' | age, time, treatment | Aged Mice are Unable to Mount an Effective Myeloid Response to Sepsis |
-1.1 | | Lemd3 | 'none; wasp knockout' vs 'none; wild type' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
-1.1 | | Lemd3 | 'tristetrapolin knockout' vs 'wild type' in 'actinomycin D' at '90 minute' | compound, genotype, time | Transcription profiling by array of fibroblasts from TTP knock out mice |
1.1 | | Lemd3 | 'untreated; Csf2rb-/-' vs 'untreated; wild type' | clinical history, genotype | Mouse GM-CSF-related alveolar macrophage genome-wide expression data |
1.1 | | Lemd3 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-1.1 | | Lemd3 | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
1.1 | | Lemd3 | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1 | | Lemd3 | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-1 | | Lemd3 | 'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1 | | Lemd3 | 'renin-expression' vs 'control' | phenotype | Expression data from mouse bone marrow cells expressing renin driven expression of green fluorescent protein. |
-1 | | Lemd3 | 'acute oropharyngeal candidiasis' vs 'healthy' in wild type mice | compound, disease, genotype, sex | Transcription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis |
-1 | | Lemd3 | 'glioblastoma multiforme' vs 'normal' | disease | Analysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus. |
-1 | | Lemd3 | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-1 | | Lemd3 | 'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day' | growth condition, time | Transcription profiling of primary mouse hepatocytes under different culture conditions |
1 | | Lemd3 | '4-oxoretinoic acid; 5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA Seq of wildtype and Rarb KO HSCs after 24h of in vitro culture and treatment |
1 | | Lemd3 | 'Mxd1 knockdown by siRNA' vs 'wild type' at '3 day' | phenotype, time | 3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1 |
1 | | Lemd3 | 'erythroblast' vs 'hematopoietic stem cell' | cell type | Transcription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells |
1 | | Lemd3 | 'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '20 to 24 month mice' | age, time, treatment | Aged Mice are Unable to Mount an Effective Myeloid Response to Sepsis |
