ensmusg00000043857 (Mgat5b)

mus musculus

mannoside acetylglucosaminyltransferase 5, isoenzyme B

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Mus musculus
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Showing 4 experiments:
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9 in 3 strains - CD1
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2
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14 - embryonic day 10.5
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Gregg et al - C57BL/6J
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Proteomics
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Transcriptomics
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-9.1
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4
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
6.4404 × 10-4-9.1
Mgat5b'Cox6a2 knockout' vs 'wild type'phenotypeRNA-seq of PV+ interneurons in WT and Cox6a2-/- mice to unravel the molecular signaling that contributes to the increase in oxidative stress and metabolic dysregulation following Cox6a2 knockout.
Adjusted p-valueLog2-fold change
3.7223 × 10-94
Mgat5b'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
4.0794 × 10-93.9
Mgat5b'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
1.1012 × 10-53.8
Mgat5b'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
6.8821 × 10-443.5
Mgat5b'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
1.1317 × 10-73.5
Mgat5b'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
2.0034 × 10-63.5
Mgat5b'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
3.4255 × 10-2-3.1
Mgat5b'neural stem cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
7.217 × 10-132.9
Mgat5b'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
7.4733 × 10-6-2.9
Mgat5b'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
4.1579 × 10-3-2.6
Mgat5b'Trp53 knockout' vs 'wild type genotype' in 'Nutlin-3a; 10 micromolar'compound, phenotypeResidual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy
Adjusted p-valueLog2-fold change
1.5917 × 10-22.6
Mgat5b'colitis' at '8 day' vs 'normal' at '0 day'disease, timeTemporal transcriptomic changes during DSS colitis development and resolution.
Adjusted p-valueLog2-fold change
2.2942 × 10-2-2.6
Mgat5b'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.7106 × 10-75-2.5
Mgat5b'proliferating progenitor' vs 'differentiating progenitor'cell typeTranscription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line
Adjusted p-valueLog2-fold change
1.5808 × 10-22.5
Mgat5b'soticlestat; 30 milligram per kilogram' vs 'none' in 'astrocyte; none'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
1.8432 × 10-2-2.5
Mgat5b'status epilepticus' vs 'none' in 'astrocyte; soticlestat; 30 milligram per kilogram'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
9.6286 × 10-4-2.4
Mgat5b'Trp53 Arg178Asp' vs 'wild type genotype' in 'Nutlin-3a; 10 micromolar'compound, phenotypeResidual tumor suppressor activities of tumorigenic p53 mutants enhance survival under chemotherapy
Adjusted p-valueLog2-fold change
3.4678 × 10-62.2
Mgat5b'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle'age, genotype, organism partTranscription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse
Adjusted p-valueLog2-fold change
1.2219 × 10-42.2
Mgat5b'P19; transduced with NeuroD2 lentivirus' vs 'P19; control'cell line, treatmentGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
Adjusted p-valueLog2-fold change
2.0791 × 10-42.2
Mgat5b'stabilization-competent' vs 'stabilization-incompetent' in '22 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
2.3713 × 10-6-1.9
Mgat5b'7 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
2.7573 × 10-21.9
Mgat5b'uterine-specific Tsc2-null' vs 'wild type' in 'oopherectomized'genotype, treatmentTranscription profiling by high throughput sequencing of uterine-specific Tsc2-null mice
Adjusted p-valueLog2-fold change
3.2022 × 10-8-1.8
Mgat5b'6 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.2158 × 10-6-1.8
Mgat5b'10 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
2.4575 × 10-2-1.8
Mgat5b'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
3.2931 × 10-51.7
Mgat5b'Crx knockout' vs 'control' at '6 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
2.5638 × 10-51.6
Mgat5b'transplanted secondary tumors' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.9225 × 10-3-1.6
Mgat5b'mir181a1/b1 Knockout' vs 'wild type'genotypeMouse CD4+/CD8+ thymocytes from miR-181a1/b1 KO vs WT
Adjusted p-valueLog2-fold change
1.7519 × 10-21.6
Mgat5b'carotid body' vs 'adrenal medulla'organism partExpression profile of mouse carotid body and adrenal medulla [RNA-Seq]
Adjusted p-valueLog2-fold change
9.621 × 10-31.5
Mgat5b'stabilization-competent' vs 'stabilization-incompetent' in '21 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
2.7075 × 10-5-1.4
Mgat5b'diabetic pregnancy' vs 'normal'diseaseTranscription profiling by array of E10.5 embryos from diabetic pregnancies and matched controls from normal pregnancies to study the effect of maternal diabetes on transcription in the developing embryo
Adjusted p-valueLog2-fold change
2.0139 × 10-2-1.4
Mgat5b'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
4.2339 × 10-6-1.3
Mgat5b'5 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.273 × 10-5-1.3
Mgat5b'4 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
5.2987 × 10-31.3
Mgat5b'stabilization-competent' vs 'stabilization-incompetent' in '27 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
7.3934 × 10-41.1
Mgat5b'Crx knockout' vs 'control' at '20 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
1.4687 × 10-2-1.1
Mgat5b'R6/2 transgenic' vs 'wild type' in '12 week; striatum'age, genotype, organism partTranscription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks.
Adjusted p-valueLog2-fold change
2.8763 × 10-12-1
Mgat5b'Mettl6 knockout clone G6' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
3.811 × 10-7-1
Mgat5b'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
8.0346 × 10-51
Mgat5b'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
7.9137 × 10-31
Mgat5b'SARS coronavirus MA15 E protein mutant Δ5' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
2.2134 × 10-2-1
Mgat5b'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Synonym
GnT-IX
Ortholog
ENSCING00000011301 (Ciona intestinalis), MGAT5B (Danio rerio), MGAT5B (Equus caballus), mgat5b (Xenopus tropicalis), MGAT5B (Bos taurus), mtch2 (Xenopus tropicalis), ENSACAG00000027671 (Anolis carolinensis), MGAT5B (Anas platyrhynchos), ENSTNIG00000019529 (Ciona savignyi), ENSCSAVG00000005575 (Ciona savignyi), gly-2 (Caenorhabditis elegans), MGAT5B (Sus scrofa), MGAT5B (Homo sapiens), MGAT5B (Macaca mulatta), MGAT5B (Monodelphis domestica), ENSOARG00020016194 (Salmo salar), MGAT5B (Gallus gallus), MGAT5B (Chlorocebus sabaeus), MGAT5B (Dasypus novemcinctus), ENSTNIG00000011598 (Ciona savignyi), Mgat5b (Rattus norvegicus), MGAT5B (Pongo abelii), ENSOCUG00000023451 (Oryctolagus cuniculus), MGAT5B (Gorilla gorilla), ENSCING00000003581 (Ciona intestinalis), ENSACAG00000016117 (Anolis carolinensis), ENSPANG00000019997 (Papio anubis), MGAT5B (Pan troglodytes)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
5568693, 17258683, 4840907, 4524284, 4712894, 4745997, A_55_P2022509, 105107_at, 5501759, 4382993, 5372886, 1434531_at, 4692043, A_52_P7538, 4315552, 5603766, 5206816, 4742476, 5053099, 5217691, ILMN_2607740, ILMN_1248130, ILMN_2489103, 5144843, 4924860, 4406518, 4897719, 4422941, 10382866, 4729873, 5191061, 5571846, 5486380, A_51_P261388, 5458036