Interaction Viewer
Legend
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Interaction Details
Accession
EBI-2515634Type
Detection Method
Host Organism
Homo sapiens HEK293T embryonic kidney cellPositive Interaction
✔️Annotations (8)
Topic | Description |
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imex curation | |
Accepted 2010-FEB-6 by ORCHARD. | |
submitted by author | |
Harper Wade: 28th Oct 2009, Department of Pathology, Harvard Medical School, 77 Avenue Louis Pasteur, NRB 940, Boston, MA 02115 | |
23-Feb-2010: Contacted by JYOTI. | |
100 | |
orchard | |
Interactors scored using the D score which incorporates the uniqueness, the abundance of the interactor (TSC), and the reproducibility of the interaction to assign a score to each protein within each IP (the same protein in two different IPs may have distinct D scores since its TSC and reproducibility could differ). In this way, the highest scores are given to proteins in each IP that are found rarely, found in duplicate runs, and have high TSCs-all characteristics of proteins that would be considered candidate interactors. A global D score threshold (DT) is determined and all raw D scores (DR) are normalized to this value, producing DN scores. |
Publication
Title
Defining the Human Deubiquitinating Enzyme Interaction LandscapeJournal
Cell (0092-8674)Authors
Sowa ME.,Bennett EJ.,Gygi SP.,Harper JW.Publication date
01/01/2009Publication reference
PubMed: 19615732External Cross References (1)
Database | Identifier |
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Annotations (1)
Topic | Description |
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wade_harper@hms.harvard.edu,mathew_sowa@hms.harvard.edu |
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AC | Name | Type | Role | Range Positions | Linked Features | Participant Name | Participant Identifier | Participant AC | Detection Methods | Parameters | Identifiers | Cross References | Annotations |
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