Interaction Viewer

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Interaction
EBI-26178737

Interaction Details

Accession
EBI-26178737
Detection Method
validated two hybrid
Positive Interaction
✔️
External Cross References (2)
DatabaseIdentifier
doi 10.1016/j.celrep.2020.108050
imex
Annotations (9)
TopicDescription
curation depth imex curation
dataset Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
figure legend Table S2
dataset Huntington's - Publications describing interactions involved in Huntington's disease
accepted Accepted 2020-SEP-18 AT 08:17 BST AT 08:17 BST by KALPANAP
dataset Alzheimers - Interactions investigated in the context of Alzheimers disease
dataset Parkinsons - Interactions investigated in the context of Parkinsons disease
author-announcement 28-Sep-2020: Contacted by IntAct-Help.
data-processing Additional detail about bait/prey roles and clone information regarding all yeast-two hybrid experiments was provided directly by the authors as part of the submission process. Mutation effects were inferred by IntAct curators by comparing interaction detections of screened clones. Clones related to GeneID 6237 were not entered in the entry by author's request, since a potential mis-annotation issue may have arisen with those. The entry will be updated once the issue is resolved.

Publication

Title
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Journal
Cell reports
Authors
Haenig C.,Atias N.,Taylor AK.,Mazza A.,Schaefer MH.,Russ J.,Riechers SP.,Jain S.,Coughlin M.,Fontaine JF.,Freibaum BD.,Brusendorf L.,Zenkner M.,Porras P.,Stroedicke M.,Schnoegl S.,Arnsburg K.,Boeddrich A.,Pigazzini L.,Heutink P.,Taylor JP.,Kirstein J.,Andrade-Navarro MA.,Sharan R.,Wanker EE.
Publication date
01/01/2020
Publication reference
PubMed: 32814053
External Cross References (1)
DatabaseIdentifier
imex
Annotations (1)
TopicDescription
contact-email erich.w@mdc-berlin.de