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Interaction | |
EBI-34585634 | |
MI Features | |
P42336:p.Cys971Arg | |
flag tag |
Interaction Details
Accession
EBI-34585634Type
Detection Method
Host Organism
Homo sapiens SCC-25 tongue squamous carcinoma cellPositive Interaction
✔️External Cross References (1)
Database | Identifier |
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Annotations (6)
Topic | Description |
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Cancer - Interactions investigated in the context of cancer | |
imex curation | |
The total list of candidate PPIs was filtered to those that met the following criteria: SAINTexpress BFDR =< 0.05, WD percentile by bait >= 0.95, and Z-score percentile by bait >= 0.95. PPIs passing all 3 of these criteria were considered to be high-confidence PPIs. To enable visualization and analysis of PPIs by confidence score among these 3 criteria, we also calculated a PPI score: [(WD percentile by bait + Z-score percentile by bait)/2) + (1-BFDR)] / 2. | |
dd-Mon-yyyy(19-Oct-2023): Contacted by IntAct-Help. | |
ST2 ST3 | |
Accepted 2023-SEP-03 AT 10:46 BST AT 10:46 BST by KALPANAP |
Publication
Title
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.Journal
Science (New York, N.Y.)Authors
Swaney DL.,Ramms DJ.,Wang Z.,Park J.,Goto Y.,Soucheray M.,Bhola N.,Kim K.,Zheng F.,Zeng Y.,McGregor M.,Herrington KA.,O'Keefe R.,Jin N.,VanLandingham NK.,Foussard H.,Von Dollen J.,Bouhaddou M.,Jimenez-Morales D.,Obernier K.,Kreisberg JF.,Kim M.,Johnson DE.,Jura N.,Grandis JR.,Gutkind JS.,Ideker T.,Krogan NJ.Publication date
01/01/2021Publication reference
PubMed: 34591642External Cross References (1)
Database | Identifier |
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Annotations (1)
Topic | Description |
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tideker@ucsd.edu, nevan.krogan@ucsf.edu |
Showing 1 to 10 of 11 entries
Expand | Name | AC | Type | Identifier | Aliases | Description | Species | Expression System | Detection Methods | Experimental Role | Biological Role | Experimental Preparations | Parameters | Confidences | Cross References | Annotations |
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Expand | Name | AC | Type | Identifier | Aliases | Description | Species | Expression System | Detection Methods | Experimental Role | Biological Role | Experimental Preparations | Parameters | Confidences | Cross References | Annotations |
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cdc23_human | EBI-34585650 | protein | Cell division cycle protein 23 homolog | Homo sapiens | prey | unspecified role | ||||||||||
il1ap_human | EBI-34585649 | protein | Interleukin-1 receptor accessory protein | Homo sapiens | prey | unspecified role | ||||||||||
yipf3_human | EBI-34585648 | protein | Protein YIPF3 | Homo sapiens | prey | unspecified role | ||||||||||
fut8_human | EBI-34585647 | protein | Alpha-(1,6)-fucosyltransferase | Homo sapiens | prey | unspecified role | ||||||||||
irf7_human | EBI-34585646 | protein | Interferon regulatory factor 7 | Homo sapiens | prey | unspecified role | ||||||||||
p55g_human | EBI-34585645 | protein | Phosphatidylinositol 3-kinase regulatory subunit gamma | Homo sapiens | prey | unspecified role | ||||||||||
rpb7_human | EBI-34585644 | protein | DNA-directed RNA polymerase II subunit RPB7 | Homo sapiens | prey | unspecified role | ||||||||||
2aab_human | EBI-34585643 | protein | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform | Homo sapiens | prey | unspecified role | ||||||||||
p85a_human | EBI-34585642 | protein | Phosphatidylinositol 3-kinase regulatory subunit alpha | Homo sapiens | prey | unspecified role | ||||||||||
p85b_human | EBI-34585641 | protein | Phosphatidylinositol 3-kinase regulatory subunit beta | Homo sapiens | prey | unspecified role |
Showing 1 to 2 of 2 entries
AC | Name | Type | Role | Range Positions | Linked Features | Participant Name | Participant Identifier | Participant AC | Detection Methods | Parameters | Identifiers | Cross References | Annotations |
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