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ComplexViewer 2.2.1by Rappsilber LaboratoryPIK3CAPIK3R2PIK3R1PPP2R1BPOLR2GPIK3R3IRF7FUT8YIPF3IL1RAPCDC23tooltip

Legend

Node Shape
Protein: click to switch
Interaction
EBI-34585634
MI Features
P42336:p.Cys971Arg
flag tag

Interaction Details

Accession
EBI-34585634
Detection Method
anti tag coip
Positive Interaction
✔️
External Cross References (1)
DatabaseIdentifier
imex
Annotations (6)
TopicDescription
dataset Cancer - Interactions investigated in the context of cancer
curation depth imex curation
data-processing The total list of candidate PPIs was filtered to those that met the following criteria: SAINTexpress BFDR =< 0.05, WD percentile by bait >= 0.95, and Z-score percentile by bait >= 0.95. PPIs passing all 3 of these criteria were considered to be high-confidence PPIs. To enable visualization and analysis of PPIs by confidence score among these 3 criteria, we also calculated a PPI score: [(WD percentile by bait + Z-score percentile by bait)/2) + (1-BFDR)] / 2.
author-announcement dd-Mon-yyyy(19-Oct-2023): Contacted by IntAct-Help.
figure legend ST2 ST3
accepted Accepted 2023-SEP-03 AT 10:46 BST AT 10:46 BST by KALPANAP

Publication

Title
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.
Journal
Science (New York, N.Y.)
Authors
Swaney DL.,Ramms DJ.,Wang Z.,Park J.,Goto Y.,Soucheray M.,Bhola N.,Kim K.,Zheng F.,Zeng Y.,McGregor M.,Herrington KA.,O'Keefe R.,Jin N.,VanLandingham NK.,Foussard H.,Von Dollen J.,Bouhaddou M.,Jimenez-Morales D.,Obernier K.,Kreisberg JF.,Kim M.,Johnson DE.,Jura N.,Grandis JR.,Gutkind JS.,Ideker T.,Krogan NJ.
Publication date
01/01/2021
Publication reference
PubMed: 34591642
External Cross References (1)
DatabaseIdentifier
imex
Annotations (1)
TopicDescription
contact-email tideker@ucsd.edu, nevan.krogan@ucsf.edu