# ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NWW5	uniprotkb:P11912	uniprotkb:A8K560|uniprotkb:Q6IAB1|uniprotkb:Q96SR0|uniprotkb:B4DDH6|ensembl:ENSP00000249806.5|intact:EBI-6165897|uniprotkb:Q9NWW5	ensembl:ENSP00000221972.3|intact:MINT-6491159|uniprotkb:A0N775|uniprotkb:Q53FB8|intact:EBI-7797864|uniprotkb:P11912	psi-mi:cln6_human(display_short)|psi-mi:Ceroid-lipofuscinosis neuronal protein 6(display_long)|uniprotkb:CLN6(gene name)|IntAct:CLN6(author assigned name)|IntAct:"CCSB ORF ID: 2651"(author assigned name)	psi-mi:cd79a_human(display_short)|psi-mi:B-cell antigen receptor complex-associated protein alpha chain(display_long)|uniprotkb:CD79A(gene name)|uniprotkb:Membrane-bound immunoglobulin-associated protein(gene name synonym)|uniprotkb:Surface IgM-associated protein(gene name synonym)|uniprotkb:MB-1 membrane glycoprotein(gene name synonym)|uniprotkb:Ig-alpha(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:IGA(gene name synonym)|IntAct:CD79A(author assigned name)|IntAct:"CCSB ORF ID: 53890"(author assigned name)	psi-mi:"MI:1112"(two hybrid prey pooling approach)	Luck K. et al.(2017)	intact:EBI-11784632|pubmed:32296183|imex:IM-25472	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(European Bioinformatics Institute)	intact:EBI-23855345|imex:IM-25472-85143	intact-miscore:0.56|author-based confidence:0.696132052564	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	panther:PTHR16244(orthology-group)|efo:"Orphanet:228363"|refseq:NP_060352.1|refseq:NP_001397997.1|interpro:IPR029255|ensembl:ENSG00000128973.13(gene)|ensembl:ENST00000249806.11(transcript)|go:"GO:0001573"|go:"GO:0005730"|go:"GO:0005769"|go:"GO:0005783"|go:"GO:0005788"|go:"GO:0005789"|go:"GO:0007040"|go:"GO:0007042"|go:"GO:0007601"|go:"GO:0008203"|go:"GO:0016020"|go:"GO:0030163"|go:"GO:0030203"|go:"GO:0031987"|go:"GO:0035727"|go:"GO:0042803"|go:"GO:0043231"|go:"GO:0045121"|go:"GO:0045862"|go:"GO:0120146"|iedb:1042751(see-also)|iedb:1049878(see-also)|iedb:1570128(see-also)|iedb:1585659(see-also)|iedb:176507(see-also)|iedb:217678(see-also)|iedb:601286(see-also)|iedb:633686(see-also)|iedb:638407(see-also)|iedb:705804(see-also)|iedb:713069(see-also)|iedb:715985(see-also)|iedb:730476(see-also)|iedb:899170(see-also)|iedb:926143(see-also)|iedb:948089(see-also)|iedb:996964(see-also)|ensembl:ENSG00000128973.12(identity)	panther:PTHR14334(orthology-group)|efo:"Orphanet:33110"|refseq:NP_067612.1|refseq:NP_001774.1|reactome:R-HSA-983695|reactome:R-HSA-9679191|reactome:R-HSA-5690714|rcsb pdb:7XT6|rcsb pdb:7XQ8|rcsb pdb:7WSP|rcsb pdb:7WSO|rcsb pdb:1CV9|mint:P11912|interpro:IPR036179|interpro:IPR013783|interpro:IPR007110|interpro:IPR003599|interpro:IPR003598|interpro:IPR003110|iedb:958006(see-also)|iedb:861608(see-also)|iedb:861498(see-also)|iedb:859903(see-also)|iedb:850280(see-also)|iedb:850279(see-also)|iedb:849140(see-also)|iedb:848141(see-also)|iedb:848140(see-also)|iedb:848139(see-also)|iedb:844331(see-also)|iedb:844329(see-also)|iedb:839950(see-also)|iedb:839753(see-also)|iedb:838498(see-also)|iedb:837892(see-also)|iedb:837543(see-also)|iedb:763870(see-also)|iedb:760676(see-also)|iedb:760675(see-also)|iedb:760674(see-also)|iedb:760673(see-also)|iedb:732019(see-also)|iedb:729647(see-also)|iedb:720806(see-also)|iedb:699994(see-also)|iedb:693295(see-also)|iedb:659241(see-also)|iedb:637690(see-also)|iedb:629677(see-also)|iedb:601712(see-also)|iedb:576214(see-also)|iedb:575103(see-also)|iedb:571437(see-also)|iedb:568343(see-also)|iedb:529445(see-also)|iedb:525301(see-also)|iedb:520416(see-also)|iedb:520415(see-also)|iedb:508963(see-also)|iedb:492943(see-also)|iedb:462833(see-also)|iedb:462832(see-also)|iedb:441730(see-also)|iedb:2022435(see-also)|iedb:1936638(see-also)|iedb:1936637(see-also)|iedb:1907431(see-also)|iedb:1866304(see-also)|iedb:1846346(see-also)|iedb:1746306(see-also)|iedb:1726210(see-also)|iedb:1726209(see-also)|iedb:163363(see-also)|iedb:1592855(see-also)|iedb:1592854(see-also)|iedb:1592853(see-also)|iedb:1592412(see-also)|iedb:1592411(see-also)|iedb:1592410(see-also)|iedb:1583410(see-also)|iedb:1583409(see-also)|iedb:1583408(see-also)|iedb:1583407(see-also)|iedb:1581228(see-also)|ensembl:ENSG00000105369.10(gene)|ensembl:ENST00000221972.8(transcript)|go:"GO:0002250"|go:"GO:0004888"|go:"GO:0005771"|go:"GO:0005886"|go:"GO:0009897"|go:"GO:0019815"|go:"GO:0030183"|go:"GO:0042100"|go:"GO:0042113"|go:"GO:0042802"|go:"GO:0045121"|go:"GO:0050853"|go:"GO:0071755"|iedb:1003586(see-also)|iedb:1014484(see-also)|iedb:1016832(see-also)|iedb:1035821(see-also)|iedb:1044989(see-also)|iedb:1046906(see-also)|iedb:1046907(see-also)|iedb:1050003(see-also)|iedb:1060866(see-also)|iedb:1093704(see-also)|iedb:1094203(see-also)|iedb:1103172(see-also)|iedb:1112845(see-also)|iedb:1124056(see-also)|iedb:1266505(see-also)|iedb:1326171(see-also)|iedb:1327555(see-also)|iedb:1339182(see-also)|iedb:1341191(see-also)|iedb:1392757(see-also)|iedb:1397319(see-also)|iedb:1567354(see-also)|iedb:1571521(see-also)|iedb:1576779(see-also)|iedb:1577361(see-also)|ensembl:ENSG00000105369.9(identity)		comment:This prey protein was expressed using pDEST-DB, a high copy number expression vector coding for an N-terminal Gal4 BD tag.	comment:mint|function:"Defects in CD79A are a cause of non-Bruton type agammaglobulinemia [MIM:601495]. Agammaglobulinemia is an immunodeficiency disease which results in developmental defects in the maturation pathway of B-cells. Two different mutations, one at the splice donor site of intron 2 and the other at the splice acceptor site for exon 3, have been identified. Both mutations give rise to a truncated protein"|function:"Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B cells"|comment:This prey protein was expressed using pDEST-AD-AR68, a high copy number expression vector coding for a C-terminal Gal4 AD tag.	figure legend:Supplementary Table 9|full coverage:Only protein-protein interactions	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/12/13	2025/03/19	crc64:C718E6F2DC20CE0F	crc64:6E5B837409969292	-	-	gal4 dna binding domain:n-n	gal4 activation domain:c-c	0	0	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)