IPR000875
Cecropin
InterPro entry
Short name | Cecropin |
family relationships |
Description
Cecropins
[1, 2, 3] are potent antibacterial proteins that constitute a main part of the cell-free immunity of insects. Cecropins are small proteins of about 35 amino acid residues active against both Gram-positive and Gram-negative bacteria. They seem to exert a lytic action on bacterial membranes. Cecropins have been given various names, including bactericidin, lepidopteran and sarcotoxin. All of these peptides are structurally related.
References
1.Cell-free immunity in insects. Boman HG, Hultmark D. Annu. Rev. Microbiol. 41, 103-26, (1987). View articlePMID: 3318666
2.Antibacterial peptides: key components needed in immunity. Boman HG. Cell 65, 205-7, (1991). View articlePMID: 2015623
3.Cell-free immunity in Cecropia. A model system for antibacterial proteins. Boman HG, Faye I, Gudmundsson GH, Lee JY, Lidholm DA. Eur. J. Biochem. 201, 23-31, (1991). View articlePMID: 1915368
4.Rapid evolution of the male-specific antibacterial protein andropin gene in Drosophila. Date-Ito A, Kasahara K, Sawai H, Chigusa SI. J. Mol. Evol. 54, 665-70, (2002). View articlePMID: 11965438
GO terms
biological process
molecular function
- None
cellular component
Cross References
PROSITE Doc
Contributing Member Database Entry
- Pfam:PF00272